Tal-Singer Ruth

Top coauthors of Tal-Singer Ruth

Lomas David A (39 papers)

Silverman Edwin K (32 papers)

Miller Bruce E (31 papers)

Vestbo Jørgen (30 papers)

Rennard Stephen I (28 papers)

List of Tal-Singer Ruth publications

2017

Wang Zhang, Singh Richa, Miller Bruce E, Tal-Singer Ruth, Van Horn Stephanie, et al. 2017. "Sputum microbiome temporal variability and dysbiosis in chronic obstructive pulmonary disease exacerbations: an analysis of the COPDMAP study." Thorax doi:10.1136/thoraxjnl-2017-210741
Coello Christopher, Fisk Marie, Mohan Divya, Wilson Frederick J, Brown Andrew P, et al. 2017. "Quantitative analysis of dynamic 18F-FDG PET/CT for measurement of lung inflammation." EJNMMI research 7 (1) doi:10.1186/s13550-017-0291-2
Mesquita Rafael, Spina Gabriele, Pitta Fabio, Donaire-Gonzalez David, Deering Brenda M, et al. 2017. "Physical activity patterns and clusters in 1001 patients with COPD." Chronic respiratory disease 14 (3) doi:10.1177/1479972316687207
Spina Gabriele, Spruit Martijn A, Alison Jennifer, Benzo Roberto P, Calverley Peter M A, et al. 2017. "Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity." Thorax 72 (8) doi:10.1136/thoraxjnl-2016-208900
Busch-Petersen Jakob, Carpenter Donald C, Burman Miriam, Foley James, Hunsberger Gerald E, et al. 2017. "Danirixin: A Reversible and Selective Antagonist of the CXC Chemokine Receptor 2." The Journal of pharmacology and experimental therapeutics 362 (2) doi:10.1124/jpet.117.240705
Busch Robert, Hobbs Brian D, Zhou Jin, Castaldi Peter J, McGeachie Michael J, et al. 2017. "Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects." American journal of respiratory cell and molecular biology 57 (1) doi:10.1165/rcmb.2016-0331OC
Fuhlbrigge Anne L, Bengtsson Thomas, Peterson Stefan, Jauhiainen Alexandra, Eriksson Göran, et al. 2017. "A novel endpoint for exacerbations in asthma to accelerate clinical development: a post-hoc analysis of randomised controlled trials." The Lancet. Respiratory medicine 5 (7) doi:10.1016/S2213-2600(17)30218-7
Zemans Rachel L, Jacobson Sean, Keene Jason, Kechris Katerina, Miller Bruce E, et al. 2017. "Multiple biomarkers predict disease severity, progression and mortality in COPD." Respiratory research 18 (1) doi:10.1186/s12931-017-0597-7
Jones Paul W, Gelhorn Heather, Wilson Hilary, Benson Victoria S, Karlsson Niklas, et al. 2017. "Socioeconomic Status as a Determinant of Health Status Treatment Response in COPD Trials." Chronic obstructive pulmonary diseases (Miami, Fla.) 4 (2) doi:10.15326/jcopdf.4.2.2017.0132
Müllerova Hana, Gelhorn Heather, Wilson Hilary, Benson Victoria S, Karlsson Niklas, et al. 2017. "St George's Respiratory Questionnaire Score Predicts Outcomes in Patients with COPD: Analysis of Individual Patient Data in the COPD Biomarkers Qualification Consortium Database." Chronic obstructive pulmonary diseases (Miami, Fla.) 4 (2) doi:10.15326/jcopdf.4.2.2017.0131
Jones Paul W, Gelhorn Heather, Karlsson Niklas, Menjoge Shailendra, Müllerova Hana, et al. 2017. "Baseline Severity as Predictor of Change in St George's Respiratory Questionnaire Scores in Trials of Long-acting Bronchodilators with COPD Patients." Chronic obstructive pulmonary diseases (Miami, Fla.) 4 (2) doi:10.15326/jcopdf.4.2.2017.0129
Tabberer Maggie, Benson Victoria S, Gelhorn Heather, Wilson Hilary, Karlsson Niklas, et al. 2017. "The COPD Biomarkers Qualification Consortium Database: Baseline Characteristics of the St George's Respiratory Questionnaire Dataset." Chronic obstructive pulmonary diseases (Miami, Fla.) 4 (2) doi:10.15326/jcopdf.4.2.2017.0128
Jones Paul W, Gelhorn Heather, Wilson Hilary, Karlsson Niklas, Menjoge Shailendra, et al. 2017. "Responder Analyses for Treatment Effects in COPD Using the St George's Respiratory Questionnaire." Chronic obstructive pulmonary diseases (Miami, Fla.) 4 (2) doi:10.15326/jcopdf.4.2.2017.0130
Yang Lucy, Cheriyan Joseph, Gutterman David D, Mayer Ruth J, Ament Zsuzsanna, et al. 2017. "Mechanisms of Vascular Dysfunction in COPD and Effects of a Novel Soluble Epoxide Hydrolase Inhibitor in Smokers." Chest 151 (3) doi:10.1016/j.chest.2016.10.058
Hobbs Brian D, de Jong Kim, Lamontagne Maxime, Bossé Yohan, Shrine Nick, et al. 2017. "Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis." Nature genetics 49 (3) doi:10.1038/ng.3752
Chen Delphine L, Cheriyan Joseph, Chilvers Edwin R, Choudhury Gourab, Coello Christopher, et al. 2017. "Quantification of Lung PET Images: Challenges and Opportunities." Journal of nuclear medicine : official publication, Society of Nuclear Medicine 58 (2) doi:10.2967/jnumed.116.184796

2016

Sand Jannie M B, Leeming Diana J, Byrjalsen Inger, Bihlet Asger R, Lange Peter, et al. 2016. "High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD - results from the ECLIPSE study." Respiratory research 17 (1) doi:10.1186/s12931-016-0440-6
Andrianopoulos Vasileios, Celli Bartolome R, Franssen Frits M E, Pinto-Plata Victor M, Calverley Peter M A, et al. 2016. "Determinants of exercise-induced oxygen desaturation including pulmonary emphysema in COPD: Results from the ECLIPSE study." Respiratory medicine 119 doi:10.1016/j.rmed.2016.08.023
Celli Bartolome, Tetzlaff Kay, Criner Gerard, Polkey Michael I, Sciurba Frank, et al. 2016. "The 6-minute Walk Test as a COPD Stratification Tool: Insights From the COPD Biomarker Qualification Consortium." American journal of respiratory and critical care medicine doi:10.1164/rccm.201508-1653OC
Joppa Pavol, Tkacova Ruzena, Franssen Frits M E, Hanson Corrine, Rennard Stephen I, et al. 2016. "Sarcopenic Obesity, Functional Outcomes, and Systemic Inflammation in Patients With Chronic Obstructive Pulmonary Disease." Journal of the American Medical Directors Association doi:10.1016/j.jamda.2016.03.020
Lazaar Aili L, Yang Lucy, Boardley Rebecca L, Goyal Navin S, Robertson Jonathan, et al. 2016. "Pharmacokinetics, pharmacodynamics and adverse event profile of GSK2256294, a novel soluble epoxide hydrolase inhibitor." British journal of clinical pharmacology 81 (5) doi:10.1111/bcp.12855
Wang Zhang, Bafadhel Mona, Haldar Koirobi, Spivak Aaron, Mayhew David, et al. 2016. "Lung microbiome dynamics in COPD exacerbations." The European respiratory journal 47 (4) doi:10.1183/13993003.01406-2015
Yohannes Abebaw M, Müllerová Hana, Hanania Nicola A, Lavoie Kim, Tal-Singer Ruth, et al. 2016. "Long-term Course of Depression Trajectories in Patients With COPD: A 3-Year Follow-up Analysis of the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints Cohort." Chest 149 (4) doi:10.1016/j.chest.2015.10.081
Rabinovich Roberto A, Miller Bruce E, Wrobel Karolina, Ranjit Kareshma, Williams Michelle C, et al. 2016. "Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD." The European respiratory journal doi:10.1183/13993003.01824-2015
Miller Bruce E, Tal-Singer Ruth, Rennard Stephen I, Furtwaengler Armin, Leidy Nancy, et al. 2016. "Plasma Fibrinogen Qualification as a Drug Development Tool in Chronic Obstructive Pulmonary Disease. Perspective of the Chronic Obstructive Pulmonary Disease Biomarker Qualification Consortium." American journal of respiratory and critical care medicine 193 (6) doi:10.1164/rccm.201509-1722PP
Chang Yale, Glass Kimberly, Liu Yang-Yu, Silverman Edwin K, Crapo James D, et al. 2016. "COPD subtypes identified by network-based clustering of blood gene expression." Genomics 107 (2-3) doi:10.1016/j.ygeno.2016.01.004
Faner Rosa, Cruz Tamara, Casserras Teresa, López-Giraldo Alejandra, Noell Guillaume, et al. 2016. "Network Analysis of Lung Transcriptomics Reveals a Distinct B Cell Signature in Emphysema." American journal of respiratory and critical care medicine doi:10.1164/rccm.201507-1311OC
Kreindler James L, Watkins Michael L, Lettis Sally, Tal-Singer Ruth, Locantore Nicholas 2016. "Effect of inhaled corticosteroids on blood eosinophil count in steroid-naïve patients with COPD." BMJ open respiratory research 3 (1) doi:10.1136/bmjresp-2016-000151

2015

Yonchuk John G, Silverman Edwin K, Bowler Russell P, Agustí Alvar, Lomas David A, et al. 2015. "Circulating soluble receptor for advanced glycation end products (sRAGE) as a biomarker of emphysema and the RAGE axis in the lung." American journal of respiratory and critical care medicine 192 (7) doi:10.1164/rccm.201501-0137PP
Spina Gabriele, Casale Pierluigi, Albert Paul S, Alison Jennifer, Garcia-Aymerich Judith, et al. 2015. "Identifying Physical Activity Profiles in COPD Patients Using Topic Models." IEEE journal of biomedical and health informatics 19 (5) doi:10.1109/JBHI.2015.2432033
Andrianopoulos Vasileios, Wouters Emiel F M, Pinto-Plata Victor M, Vanfleteren Lowie E G W, Bakke Per S, et al. 2015. "Prognostic value of variables derived from the six-minute walk test in patients with COPD: Results from the ECLIPSE study." Respiratory medicine 109 (9) doi:10.1016/j.rmed.2015.06.013
Cho Michael H, Castaldi Peter J, Hersh Craig P, Hobbs Brian D, Barr R Graham, et al. 2015. "A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes." American journal of respiratory and critical care medicine 192 (5) doi:10.1164/rccm.201501-0148OC
Thomsen Laura H, Shaker Saher B, Dirksen Asger, Pedersen Jesper H, Tal-Singer Ruth, et al. 2015. "Correlation Between Emphysema and Lung Function in Healthy Smokers and Smokers With COPD." Chronic obstructive pulmonary diseases (Miami, Fla.) 2 (3) doi:10.15326/jcopdf.2.3.2014.0154
Wilke Sarah, Jones Paul W, Müllerova H, Vestbo Jørgen, Tal-Singer Ruth, et al. 2015. "One-year change in health status and subsequent outcomes in COPD." Thorax 70 (5) doi:10.1136/thoraxjnl-2014-205697
Rennard Stephen I, Locantore Nicholas, Delafont Bruno, Tal-Singer Ruth, Silverman Edwin K, et al. 2015. "Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis." Annals of the American Thoracic Society 12 (3) doi:10.1513/AnnalsATS.201403-125OC
Castaldi Peter J, Cho Michael H, Zhou Xiaobo, Qiu Weiliang, Mcgeachie Michael, et al. 2015. "Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci." Human molecular genetics 24 (4) doi:10.1093/hmg/ddu525
Betts Joanna C, Mayer Ruth J, Tal-Singer Ruth, Warnock Linda, Clayton Chris, et al. 2015. "Gene expression changes caused by the p38 MAPK inhibitor dilmapimod in COPD patients: analysis of blood and sputum samples from a randomized, placebo-controlled clinical trial." Pharmacology research & perspectives 3 (1) doi:10.1002/prp2.94
Miller Bruce E, Mistry Sunil, Smart Kevin, Connolly Paul, Carpenter Donald C, et al. 2015. "The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756)--a selective CXCR2 antagonist --in healthy adult subjects." BMC pharmacology & toxicology 16 doi:10.1186/s40360-015-0017-x
Kohli Puja, Pinto-Plata Victor, Divo Miguel, Malhotra Atul, Harris R Scott, et al. 2015. "Functional capacity, health status, and inflammatory biomarker profile in a cohort of patients with chronic obstructive pulmonary disease." Journal of cardiopulmonary rehabilitation and prevention 35 (5) doi:10.1097/HCR.0000000000000123
Mannino David M, Tal-Singer Ruth, Lomas David A, Vestbo Jorgen, Graham Barr R, et al. 2015. "Plasma Fibrinogen as a Biomarker for Mortality and Hospitalized Exacerbations in People with COPD." Chronic obstructive pulmonary diseases (Miami, Fla.) 2 (1) doi:10.15326/jcopdf.2.1.2014.0138

2014

Janssen Daisy J A, Müllerova Hana, Agusti Alvar, Yates Julie C, Tal-Singer Ruth, et al. 2014. "Persistent systemic inflammation and symptoms of depression among patients with COPD in the ECLIPSE cohort." Respiratory medicine 108 (11) doi:10.1016/j.rmed.2014.07.013
McDonald Merry-Lynn N, Cho Michael H, Sørheim Inga-Cecilie, Lutz Sharon M, Castaldi Peter J, et al. 2014. "Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 51 (5) doi:10.1165/rcmb.2014-0135OC
Johansson Sofie Lock, Roberts Nassim Bazeghi, Schlosser Anders, Andersen Claus B, Carlsen Jørn, et al. 2014. "Microfibrillar-associated protein 4: a potential biomarker of chronic obstructive pulmonary disease." Respiratory medicine 108 (9) doi:10.1016/j.rmed.2014.06.003
Mohan Divya, Gale Nichola S, McEniery Carmel M, Bolton Charlotte E, Cockcroft John R, et al. 2014. "Evaluating the role of inflammation in chronic airways disease: the ERICA study." COPD 11 (5) doi:10.3109/15412555.2014.898031
Williams Michelle C, Murchison John T, Edwards Lisa D, Agustí Alvar, Bakke Per, et al. 2014. "Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality." Thorax 69 (8) doi:10.1136/thoraxjnl-2012-203151
Wells J Michael, O'Reilly Philip J, Szul Tomasz, Sullivan Daniel I, Handley Guy, et al. 2014. "An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 190 (1) doi:10.1164/rccm.201401-0145OC
Faner Rosa, Tal-Singer Ruth, Riley John H, Celli Bartolomé, Vestbo Jørgen, et al. 2014. "Lessons from ECLIPSE: a review of COPD biomarkers." Thorax 69 (7) doi:10.1136/thoraxjnl-2013-204778
Vestbo Jørgen, Agusti Alvar, Wouters Emiel F M, Bakke Per, Calverley Peter M A, et al. 2014. "Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team." American journal of respiratory and critical care medicine 189 (9) doi:10.1164/rccm.201311-2006PP
Cho Michael H, McDonald Merry-Lynn N, Zhou Xiaobo, Mattheisen Manuel, Castaldi Peter J, et al. 2014. "Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis." The Lancet. Respiratory medicine 2 (3) doi:10.1016/S2213-2600(14)70002-5
Hersh Craig P, Make Barry J, Lynch David A, Barr R Graham, Bowler Russell P, et al. 2014. "Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus." BMC pulmonary medicine 14 doi:10.1186/1471-2466-14-164
O'Neal Wanda K, Anderson Wayne, Basta Patricia V, Carretta Elizabeth E, Doerschuk Claire M, et al. 2014. "Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study." Journal of translational medicine 12 doi:10.1186/1479-5876-12-9
Singh Dave, Fox Steven M, Tal-Singer Ruth, Bates Stewart, Riley John H, Celli Bartolome 2014. "Altered gene expression in blood and sputum in COPD frequent exacerbators in the ECLIPSE cohort." PloS one 9 (9) doi:10.1371/journal.pone.0107381
Menche Jörg, Sharma Amitabh, Cho Michael H, Mayer Ruth J, Rennard Stephen I, et al. 2014. "A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease." BMC systems biology 8 Suppl 2 doi:10.1186/1752-0509-8-S2-S8

2013

Cheng Donavan T, Kim Deog Kyeom, Cockayne Debra A, Belousov Anton, Bitter Hans, et al. 2013. "Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 188 (8) doi:10.1164/rccm.201302-0247OC
Miller Joy, Edwards Lisa D, Agustí Alvar, Bakke Per, Calverley Peter M A, et al. 2013. "Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort." Respiratory medicine 107 (9) doi:10.1016/j.rmed.2013.05.001
Cahn Anthony, Tal-Singer Ruth, Pouliquen Isabelle J, Mehta Rashmi, Preece Andrew, et al. 2013. "Safety, tolerability, pharmacokinetics and pharmacodynamics of single and repeat inhaled doses of umeclidinium in healthy subjects: two randomized studies." Clinical drug investigation 33 (7) doi:10.1007/s40261-013-0088-7
Agusti Alvar, Edwards Lisa D, Celli Bartolomé, Macnee William, Calverley Peter M A, et al. 2013. "Characteristics, stability and outcomes of the gold 2011 copd groups in the eclipse cohort." The European respiratory journal doi:10.1183/09031936.00195212
Casaburi Richard, Celli Bartolome, Crapo James, Criner Gerard, Croxton Thomas, et al. 2013. "The COPD Biomarker Qualification Consortium (CBQC)." COPD 10 (3) doi:10.3109/15412555.2012.752807
Moss Richard B, Mistry Sunil J, Konstan Michael W, Pilewski Joseph M, Kerem Eitan, et al. 2013. "Safety and early treatment effects of the CXCR2 antagonist SB-656933 in patients with cystic fibrosis." Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 12 (3) doi:10.1016/j.jcf.2012.08.016
Coxson Harvey O, Dirksen Asger, Edwards Lisa D, Yates Julie C, Agusti Alvar, et al. 2013. "The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: a prospective analysis from the ECLIPSE study." The Lancet. Respiratory medicine 1 (2) doi:10.1016/S2213-2600(13)70006-7
Polkey Michael I, Spruit Martijn A, Edwards Lisa D, Watkins Michael L, Pinto-Plata Victor, et al. 2013. "Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization." American journal of respiratory and critical care medicine 187 (4) doi:10.1164/rccm.201209-1596OC
Tal-Singer Ruth, Cahn Anthony, Mehta Rashmi, Preece Andrew, Crater Glenn, et al. 2013. "Initial assessment of single and repeat doses of inhaled umeclidinium in patients with chronic obstructive pulmonary disease: two randomised studies." European journal of pharmacology 701 (1-3) doi:10.1016/j.ejphar.2012.12.019
Natanek Samantha A, Gosker Harry R, Slot Ilse Gm, Marsh Gemma S, Hopkinson Nicholas S, et al. 2013. "Heterogeneity of quadriceps muscle phenotype in chronic obstructive pulmonary disease (COPD); implications for stratified medicine?" Muscle & nerve doi:10.1002/mus.23784
Rutten Erica P A, Calverley Peter M A, Casaburi Richard, Agusti Alvar, Bakke Per, et al. 2013. "Changes in body composition in patients with chronic obstructive pulmonary disease: do they influence patient-related outcomes?" Annals of nutrition & metabolism 63 (3) doi:10.1159/000353211

2012

Kim Deog Kyeom, Cho Michael H, Hersh Craig P, Lomas David A, Miller Bruce E, et al. 2012. "Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 186 (12) doi:10.1164/rccm.201206-1013OC
Steiner Michael C, Roubenoff Ronenn, Tal-Singer Ruth, Polkey Michael I 2012. "Prospects for the development of effective pharmacotherapy targeted at the skeletal muscles in chronic obstructive pulmonary disease: a translational review." Thorax 67 (12) doi:10.1136/thoraxjnl-2012-201765
Ubhi Baljit K, Cheng Kian Kai, Dong Jiyang, Janowitz Tobias, Jodrell Duncan, et al. 2012. "Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD." Molecular bioSystems 8 (12) doi:10.1039/c2mb25194a
Ubhi Baljit K, Riley John H, Shaw Paul A, Lomas David A, Tal-Singer Ruth, et al. 2012. "Metabolic profiling detects biomarkers of protein degradation in COPD patients." The European respiratory journal 40 (2) doi:10.1183/09031936.00112411
Albert Paul, Agusti Alvar, Edwards Lisa, Tal-Singer Ruth, Yates Julie, et al. 2012. "Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease." Thorax 67 (8) doi:10.1136/thoraxjnl-2011-201458
Mannino David M, Valvi Deepa, Mullerova Hana, Tal-Singer Ruth 2012. "Fibrinogen, COPD and mortality in a nationally representative U.S. cohort." COPD 9 (4) doi:10.3109/15412555.2012.668249
Duvoix Annelyse, Dickens Jenny, Haq Imran, Mannino David, Miller Bruce, et al. 2012. "Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease." Thorax doi:10.1136/thoraxjnl-2012-201871
Celli Bartolome R, Locantore Nicholas, Yates Julie, Tal-Singer Ruth, Miller Bruce E, et al. 2012. "Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 185 (10) doi:10.1164/rccm.201110-1792OC
Waschki Benjamin, Spruit Martijn A, Watz Henrik, Albert Paul S, Shrikrishna Dinesh, et al. 2012. "Physical activity monitoring in COPD: compliance and associations with clinical characteristics in a multicenter study." Respiratory medicine 106 (4) doi:10.1016/j.rmed.2011.10.022
Riddoch-Contreras Joanna, George Tomasz, Natanek Samantha A, Marsh Gemma S, Hopkinson Nicholas S, et al. 2012. "p38 mitogen-activated protein kinase is not activated in the quadriceps of patients with stable chronic obstructive pulmonary disease." COPD 9 (2) doi:10.3109/15412555.2011.644359
Spruit Martijn A, Polkey Michael I, Celli Bartolome, Edwards Lisa D, Watkins Michael L, et al. 2012. "Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease." Journal of the American Medical Directors Association 13 (3) doi:10.1016/j.jamda.2011.06.009
Lomas David A, Lipson David A, Miller Bruce E, Willits Lisa, Keene Oliver, et al. 2012. "An oral inhibitor of p38 MAP kinase reduces plasma fibrinogen in patients with chronic obstructive pulmonary disease." Journal of clinical pharmacology 52 (3) doi:10.1177/0091270010397050
Cho Michael H, Castaldi Peter J, Wan Emily S, Siedlinski Mateusz, Hersh Craig P, et al. 2012. "A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13." Human molecular genetics 21 (4) doi:10.1093/hmg/ddr524
Valvi Deepa, Mannino David M, Müllerova Hana, Tal-Singer Ruth 2012. "Fibrinogen, chronic obstructive pulmonary disease (COPD) and outcomes in two United States cohorts." International journal of chronic obstructive pulmonary disease 7 doi:10.2147/COPD.S29892
Agustí Alvar, Edwards Lisa D, Rennard Stephen I, MacNee William, Tal-Singer Ruth, et al. 2012. "Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype." PloS one 7 (5) doi:10.1371/journal.pone.0037483

2011

Vestbo Jørgen, Edwards Lisa D, Scanlon Paul D, Yates Julie C, Agusti Alvar, et al. 2011. "Changes in forced expiratory volume in 1 second over time in COPD." The New England journal of medicine 365 (13) doi:10.1056/NEJMoa1105482
Lazaar Aili L, Sweeney Lisa E, MacDonald Alexander J, Alexis Neil E, Chen Chao, Tal-Singer Ruth 2011. "SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans." British journal of clinical pharmacology 72 (2) doi:10.1111/j.1365-2125.2011.03968.x
Crim Courtney, Celli Bartolome, Edwards Lisa D, Wouters Emiel, Coxson Harvey O, et al. 2011. "Respiratory system impedance with impulse oscillometry in healthy and COPD subjects: ECLIPSE baseline results." Respiratory medicine 105 (7) doi:10.1016/j.rmed.2011.01.010
MacNee William, Rennard Stephen I, Hunt John F, Edwards Lisa D, Miller Bruce E, et al. 2011. "Evaluation of exhaled breath condensate pH as a biomarker for COPD." Respiratory medicine 105 (7) doi:10.1016/j.rmed.2011.02.009
Singh Dave, Fox Steven M, Tal-Singer Ruth, Plumb Jonathan, Bates Stewart, et al. 2011. "Induced sputum genes associated with spirometric and radiological disease severity in COPD ex-smokers." Thorax 66 (6) doi:10.1136/thx.2010.153767
Sin Don D, Miller Bruce E, Duvoix Annelyse, Man S F Paul, Zhang Xuekui, et al. 2011. "Serum PARC/CCL-18 concentrations and health outcomes in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 183 (9) doi:10.1164/rccm.201008-1220OC
Foreman Marilyn G, Kong Xiangyang, DeMeo Dawn L, Pillai Sreekumar G, Hersh Craig P, et al. 2011. "Polymorphisms in surfactant protein-D are associated with chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 44 (3) doi:10.1165/rcmb.2009-0360OC
Qiu Weiliang, Cho Michael H, Riley John H, Anderson Wayne H, Singh Dave, et al. 2011. "Genetics of sputum gene expression in chronic obstructive pulmonary disease." PloS one 6 (9) doi:10.1371/journal.pone.0024395
Dickens Jennifer A, Miller Bruce E, Edwards Lisa D, Silverman Edwin K, Lomas David A, Tal-Singer Ruth 2011. "COPD association and repeatability of blood biomarkers in the ECLIPSE cohort." Respiratory research 12 doi:10.1186/1465-9921-12-146

2010

Hurst John R, Vestbo Jørgen, Anzueto Antonio, Locantore Nicholas, Müllerova Hana, et al. 2010. "Susceptibility to exacerbation in chronic obstructive pulmonary disease." The New England journal of medicine 363 (12) doi:10.1056/NEJMoa0909883
Spruit Martijn A, Watkins Michael L, Edwards Lisa D, Vestbo Jørgen, Calverley Peter M A, et al. 2010. "Determinants of poor 6-min walking distance in patients with COPD: the ECLIPSE cohort." Respiratory medicine 104 (6) doi:10.1016/j.rmed.2009.12.007
Cho Michael H, Boutaoui Nadia, Klanderman Barbara J, Sylvia Jody S, Ziniti John P, et al. 2010. "Variants in FAM13A are associated with chronic obstructive pulmonary disease." Nature genetics 42 (3) doi:10.1038/ng.535
Basanta Maria, Jarvis Roger M, Xu Yun, Blackburn Gavin, Tal-Singer Ruth, et al. 2010. "Non-invasive metabolomic analysis of breath using differential mobility spectrometry in patients with chronic obstructive pulmonary disease and healthy smokers." The Analyst 135 (2) doi:10.1039/b916374c
Singh Dave, Edwards Lisa, Tal-Singer Ruth, Rennard Stephen 2010. "Sputum neutrophils as a biomarker in COPD: findings from the ECLIPSE study." Respiratory research 11 doi:10.1186/1465-9921-11-77
Singh Dave, Smyth Lucy, Borrill Zoe, Sweeney Lisa, Tal-Singer Ruth 2010. "A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients." Journal of clinical pharmacology 50 (1) doi:10.1177/0091270009347873
Agusti Alvar, Calverley Peter M A, Celli Bartolome, Coxson Harvey O, Edwards Lisa D, et al. 2010. "Characterisation of COPD heterogeneity in the ECLIPSE cohort." Respiratory research 11 doi:10.1186/1465-9921-11-122

2008

Alexis Neil E, Lay John C, Haczku Angela, Gong Henry, Linn William, et al. 2008. "Fluticasone propionate protects against ozone-induced airway inflammation and modified immune cell activation markers in healthy volunteers." Environmental health perspectives 116 (6) doi:10.1289/ehp.10981
Borrill Zoë L, Houghton Catherine M, Tal-Singer Ruth, Vessey S Rupert, Faiferman Isidore, et al. 2008. "The use of plethysmography and oscillometry to compare long-acting bronchodilators in patients with COPD." British journal of clinical pharmacology 65 (2) doi:10.1111/j.1365-2125.2007.03013.x

2007

Nicholson Grant C, Tennant Rachel C, Carpenter Donald C, Sarau Henry M, Kon Onn Min, et al. 2007. "A novel flow cytometric assay of human whole blood neutrophil and monocyte CD11b levels: upregulation by chemokines is related to receptor expression, comparison with neutrophil shape change, and effects of a chemokine receptor (CXCR2) antagonist." Pulmonary pharmacology & therapeutics 20 (1) doi:10.1016/j.pupt.2005.11.009

2005

Holz Olaf, Tal-Singer Ruth, Kanniess Frank, Simpson Kathy J, Gibson Anthony, et al. 2005. "Validation of the human ozone challenge model as a tool for assessing anti-inflammatory drugs in early development." Journal of clinical pharmacology 45 (5) doi:10.1177/0091270004273527

2003

Hess Simone, Peters Jan, Bartling Gerda, Rheinheimer Claudia, Hegde Priti, et al. 2003. "More than just innate immunity: comparative analysis of Chlamydophila pneumoniae and Chlamydia trachomatis effects on host-cell gene regulation." Cellular microbiology 5 (11) doi: