Sin Don D

Top coauthors of Sin Don D

Man S F Paul (76 papers)

Paré Peter D (27 papers)

Coxson Harvey O (25 papers)

Bossé Yohan (24 papers)

Hogg James C (22 papers)

List of Sin Don D publications

2017

Leitao Filho Fernando Sergio, Alotaibi Nawaf M, Yamasaki Kei, Ngan David A, Sin Don D 2017. "The role of beta-blockers in the management of chronic obstructive pulmonary disease." Expert review of respiratory medicine doi:10.1080/17476348.2018.1419869
de Vries Maaike, Faiz Alen, Woldhuis Roy R, Postma Dirkje S, de Jong Tristan V, et al. 2017. "Lung tissue gene-expression signature for the ageing lung in COPD." Thorax doi:10.1136/thoraxjnl-2017-210074
Roberts James M, Dai Darlene L Y, Hollander Zsuzsanna, Ng Raymond T, Tebbutt Scott J, et al. 2017. "Multiple reaction monitoring mass spectrometry to identify novel plasma protein biomarkers of treatment response in cystic fibrosis pulmonary exacerbations." Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society doi:10.1016/j.jcf.2017.10.013
Allen Richard J, Porte Joanne, Braybrooke Rebecca, Flores Carlos, Fingerlin Tasha E, et al. 2017. "Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study." The Lancet. Respiratory medicine 5 (11) doi:10.1016/S2213-2600(17)30387-9
Tammemagi Martin C, Schmidt Heidi, Martel Simon, McWilliams Annette, Goffin John R, et al. 2017. "Participant selection for lung cancer screening by risk modelling (the Pan-Canadian Early Detection of Lung Cancer [PanCan] study): a single-arm, prospective study." The Lancet. Oncology 18 (11) doi:10.1016/S1470-2045(17)30597-1
Obeidat Ma'en, Li Xuan, Burgess Stephen, Zhou Guohai, Fishbane Nick, et al. 2017. "Surfactant protein D is a causal risk factor for COPD: results of Mendelian randomisation." The European respiratory journal 50 (5) doi:10.1183/13993003.00657-2017
Burgel Pierre-Régis, Paillasseur Jean-Louis, Janssens Wim, Piquet Jacques, Ter Riet Gerben, et al. 2017. "A simple algorithm for the identification of clinical COPD phenotypes." The European respiratory journal 50 (5) doi:10.1183/13993003.01034-2017
Brown Kirstin E, Sin Don D, Voelker Helen, Connett John E, Niewoehner Dennis E, Kunisaki Ken M 2017. "Serum bilirubin and the risk of chronic obstructive pulmonary disease exacerbations." Respiratory research 18 (1) doi:10.1186/s12931-017-0664-0
Reed Robert M, Cabral Howard J, Dransfield Mark T, Eberlein Michael, Merlo Christian A, et al. 2017. "Survival of Lung Transplant Candidates with COPD: BODE Score Reconsidered." Chest doi:10.1016/j.chest.2017.10.008
Obeidat Ma'en, Nie Yunlong, Fishbane Nick, Li Xuan, Bossé Yohan, et al. 2017. "Integrative Genomics of Emphysema-Associated Genes Reveals Potential Disease Biomarkers." American journal of respiratory cell and molecular biology 57 (4) doi:10.1165/rcmb.2016-0284OC
Leung Janice M, Sin Don D 2017. "Asthma-COPD overlap syndrome: pathogenesis, clinical features, and therapeutic targets." BMJ (Clinical research ed.) 358 doi:
Kirby Miranda, Tanabe Naoya, Tan Wan C, Zhou Guohai, Obeidat Ma'en, et al. 2017. "Total Airway Count on Computed Tomography and the Risk of COPD Progression: Findings from a Population-based Study." American journal of respiratory and critical care medicine doi:10.1164/rccm.201704-0692OC
Raymakers Adam J N, Sadatsafavi Mohsen, Sin Don D, De Vera Mary A, Lynd Larry D 2017. "The Impact of Statin Drug Use on All-Cause Mortality in Patients With COPD: A Population-Based Cohort Study." Chest 152 (3) doi:10.1016/j.chest.2017.02.002
Aaron Shawn D, Tan Wan C, Bourbeau Jean, Sin Don D, Loves Robyn H, et al. 2017. "Diagnostic Instability and Reversals of Chronic Obstructive Pulmonary Disease Diagnosis in Individuals with Mild to Moderate Airflow Obstruction." American journal of respiratory and critical care medicine 196 (3) doi:10.1164/rccm.201612-2531OC
Hirano Yuki, Choi Alex, Tsuruta Masashi, Jaw Jen Erh, Oh Yeni, et al. 2017. "Surfactant protein-D deficiency suppresses systemic inflammation and reduces atherosclerosis in ApoE knockout mice." Cardiovascular research 113 (10) doi:10.1093/cvr/cvx067
Cressman Sonya, Peacock Stuart J, Tammemägi Martin C, Evans William K, Leighl Natasha B, et al. 2017. "The Cost-Effectiveness of High-Risk Lung Cancer Screening and Drivers of Program Efficiency." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 12 (8) doi:10.1016/j.jtho.2017.04.021
Woodruff Prescott G, van den Berge Maarten, Boucher Richard C, Brightling Christopher, Burchard Esteban G, et al. 2017. "American Thoracic Society/National Heart, Lung, and Blood Institute Asthma-Chronic Obstructive Pulmonary Disease Overlap Workshop Report." American journal of respiratory and critical care medicine 196 (3) doi:10.1164/rccm.201705-0973WS
Chen Wenjia, FitzGerald J Mark, Sin Don D, Sadatsafavi Mohsen 2017. "Excess economic burden of comorbidities in COPD: a 15-year population-based study." The European respiratory journal 50 (1) doi:10.1183/13993003.00393-2017
Ra Seung Won, Sze Marc A, Lee Eun Chong, Tam Sheena, Oh Yeni, et al. 2017. "Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori." Respiratory research 18 (1) doi:10.1186/s12931-017-0594-x
Kirby Miranda, Eddy Rachel L, Pike Damien, Svenningsen Sarah, Coxson Harvey O, et al. 2017. "MRI ventilation abnormalities predict quality-of-life and lung function changes in mild-to-moderate COPD: longitudinal TINCan study." Thorax 72 (5) doi:10.1136/thoraxjnl-2016-209770
Li Xuan, Obeidat Ma'en, Zhou Guohai, Leung Janice M, Tashkin Donald, et al. 2017. "Responsiveness to Ipratropium Bromide in Male and Female Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease." EBioMedicine 19 doi:10.1016/j.ebiom.2017.04.020
Obeidat Ma'en, Nie Yunlong, Chen Virginia, Shannon Casey P, Andiappan Anand Kumar, et al. 2017. "Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease." Respiratory research 18 (1) doi:10.1186/s12931-017-0558-1
Vogelmeier Claus F, Criner Gerard J, Martinez Fernando J, Anzueto Antonio, Barnes Peter J, et al. 2017. "Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary." Respirology (Carlton, Vic.) 22 (3) doi:10.1111/resp.13012
Vogelmeier Claus F, Criner Gerard J, Martínez Fernando J, Anzueto Antonio, Barnes Peter J, et al. 2017. "Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary." Archivos de bronconeumologia 53 (3) doi:10.1016/j.arbres.2017.02.001
Tsai Amy Po Yu, English John C, Murphy Darra, Sin Don D 2017. "Recurrent pneumothorax related to diffuse dendriform pulmonary ossification in genetically predisposed individual." Respirology case reports 5 (2) doi:10.1002/rcr2.211
Wain Louise V, Shrine Nick, Artigas María Soler, Erzurumluoglu A Mesut, Noyvert Boris, et al. 2017. "Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets." Nature genetics 49 (3) doi:10.1038/ng.3787
Vogelmeier Claus F, Criner Gerard J, Martinez Fernando J, Anzueto Antonio, Barnes Peter J, et al. 2017. "Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary." The European respiratory journal 49 (3) doi:10.1183/13993003.00214-2017
Vogelmeier Claus F, Criner Gerard J, Martinez Fernando J, Anzueto Antonio, Barnes Peter J, et al. 2017. "Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary." American journal of respiratory and critical care medicine 195 (5) doi:10.1164/rccm.201701-0218PP
Leung Janice M, Fishbane Nick, Jones Meaghan, Morin Alexander, Xu Stella, et al. 2017. "Longitudinal study of surrogate aging measures during human immunodeficiency virus seroconversion." Aging 9 (3) doi:10.18632/aging.101184
Shannon Casey P, Balshaw Robert, Chen Virginia, Hollander Zsuzsanna, Toma Mustafa, et al. 2017. "Enumerateblood - an R package to estimate the cellular composition of whole blood from Affymetrix Gene ST gene expression profiles." BMC genomics 18 (1) doi:10.1186/s12864-016-3460-1
Kirby Miranda, Yin Youbing, Tschirren Juerg, Tan Wan C, Leipsic Jonathon, et al. 2017. "A Novel Method of Estimating Small Airway Disease Using Inspiratory-to-Expiratory Computed Tomography." Respiration; international review of thoracic diseases 94 (4) doi:10.1159/000478865
Chen Yu-Wei Roy, Chen Virginia, Hollander Zsuzsanna, Leipsic Jonathon A, Hague Cameron J, et al. 2017. "C-reactive protein and N-terminal prohormone brain natriuretic peptide as biomarkers in acute exacerbations of COPD leading to hospitalizations." PloS one 12 (3) doi:10.1371/journal.pone.0174063
Martin Mickaël, Almeras Natalie, Després Jean-Pierre, Coxson Harvey O, Washko George R, et al. 2017. "Ectopic fat accumulation in patients with COPD: an ECLIPSE substudy." International journal of chronic obstructive pulmonary disease 12 doi:10.2147/COPD.S124750
Zafari Zafar, Bryan Stirling, Sin Don D, Conte Tania, Khakban Rahman, Sadatsafavi Mohsen 2017. "A Systematic Review of Health Economics Simulation Models of Chronic Obstructive Pulmonary Disease." Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20 (1) doi:10.1016/j.jval.2016.08.003
Alshabanat Abdulmajeed, Otterstatter Michael C, Sin Don D, Road Jeremy, Rempel Carmen, et al. 2017. "Impact of a COPD comprehensive case management program on hospital length of stay and readmission rates." International journal of chronic obstructive pulmonary disease 12 doi:10.2147/COPD.S124385
Sin Don D 2017. "Asthma-COPD Overlap Syndrome: What We Know and What We Don't." Tuberculosis and respiratory diseases 80 (1) doi:10.4046/trd.2017.80.1.11

2016

Shannon Casey P, Chen Virginia, Takhar Mandeep, Hollander Zsuzsanna, Balshaw Robert, et al. 2016. "SABRE: a method for assessing the stability of gene modules in complex tissues and subject populations." BMC bioinformatics 17 (1) doi:10.1186/s12859-016-1319-8
Sze Marc A, Xu Stella, Leung Janice M, Vucic Emily A, Shaipanich Tawimas, et al. 2016. "The bronchial epithelial cell bacterial microbiome and host response in patients infected with human immunodeficiency virus." BMC pulmonary medicine 16 (1) doi:10.1186/s12890-016-0303-4
Sadatsafavi Mohsen, Sin Don D, Zafari Zafar, Criner Gerard, Connett John E, et al. 2016. "The Association Between Rate and Severity of Exacerbations in Chronic Obstructive Pulmonary Disease: An Application of a Joint Frailty-Logistic Model." American journal of epidemiology doi:10.1093/aje/kww085
Hollander Zsuzsanna, DeMarco Mari L, Sadatsafavi Mohsen, McManus Bruce M, Ng Raymond T, Sin Don D 2016. "Biomarker Development in COPD: Moving from P-Values to Products to Impact Patient Care." Chest doi:10.1016/j.chest.2016.09.012
Lam Stephen, Mandrekar Sumithra J, Gesthalter Yaron, Allen Ziegler Katie L, Seisler Drew K, et al. 2016. "A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia." Cancer prevention research (Philadelphia, Pa.) doi:10.1158/1940-6207.CAPR-15-0254
Khakban Amir, Sin Don D, FitzGerald J Mark, McManus Bruce, Ng Raymond, et al. 2016. "The Projected Epidemic of COPD Hospitalizations Over the Next 15 Years: A Population Based Perspective." American journal of respiratory and critical care medicine doi:10.1164/rccm.201606-1162PP
van der Plaat Diana A, de Jong Kim, Lahousse Lies, Faiz Alen, Vonk Judith M, et al. 2016. "Genome-wide association study on the FEV1/FVC-ratio in never-smokers identifies HHIP and FAM13A." The Journal of allergy and clinical immunology doi:10.1016/j.jaci.2016.06.062
Roversi Sara, Fabbri Leonardo M, Sin Don D, Hawkins Nathaniel M, Agusti Alvar 2016. "Chronic Obstructive Pulmonary Disease and Cardiac Diseases: An Urgent Need for Integrated Care." American journal of respiratory and critical care medicine doi:10.1164/rccm.201604-0690SO
Zafari Zafar, Sin Don D, Postma Dirkje S, Löfdahl Md Claes-Göran, Vonk Judith, et al. 2016. "Individualized prediction of lung-function decline in chronic obstructive pulmonary disease." CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne doi:10.1503/cmaj.151483
Sin Don D, Miravitlles Marc, Mannino David M, Soriano Joan B, Price David, et al. 2016. "What is asthma-COPD overlap syndrome? Towards a consensus definition from a round table discussion." The European respiratory journal doi:10.1183/13993003.00436-2016
Tkacova Ruzena, Dai Darlene L Y, Vonk Judith M, Leung Janice M, Hiemstra Pieter S, et al. 2016. "Airway hyperresponsiveness in chronic obstructive pulmonary disease: A marker of asthma-chronic obstructive pulmonary disease overlap syndrome?" The Journal of allergy and clinical immunology doi:10.1016/j.jaci.2016.04.022
Obeidat Ma'en, Ding Xiaoting, Fishbane Nick, Hollander Zsuzsanna, Ng Raymond T, et al. 2016. "The Effect of Different Case Definitions of Current Smoking on the Discovery of Smoking-Related Blood Gene Expression Signatures in Chronic Obstructive Pulmonary Disease." Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco doi:10.1093/ntr/ntw129
Tam Anthony, Churg Andrew, Wright Joanne L, Zhou Steven, Kirby Miranda, et al. 2016. "Sex Differences in Airway Remodeling in a Mouse Model of Chronic Obstructive Pulmonary Disease." American journal of respiratory and critical care medicine 193 (8) doi:10.1164/rccm.201503-0487OC
Spanjer Anita I R, Menzen Mark H, Dijkstra Akkelies E, van den Berge Maarten, Boezen H Marike, et al. 2016. "A pro-inflammatory role for the Frizzled-8 receptor in chronic bronchitis." Thorax 71 (4) doi:10.1136/thoraxjnl-2015-206958
Biagioni Bradly J, Tam Sheena, Chen Yu-Wei Roy, Sin Don D, Carlsten Christopher 2016. "Effect of controlled human exposure to diesel exhaust and allergen on airway surfactant protein D, myeloperoxidase, and club (Clara) cell secretory protein 16." Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology doi:10.1111/cea.12732
Jaw Jen Erh, Tsuruta Masashi, Oh Yeni, Schipilow John, Hirano Yuki, et al. 2016. "Lung exposure to lipopolysaccharide causes atherosclerotic plaque destabilisation." The European respiratory journal doi:10.1183/13993003.00972-2015
Quon Bradley S, Dai Darlene L Y, Hollander Zsuzsanna, Ng Raymond T, Tebbutt Scott J, et al. 2016. "Discovery of novel plasma protein biomarkers to predict imminent cystic fibrosis pulmonary exacerbations using multiple reaction monitoring mass spectrometry." Thorax 71 (3) doi:10.1136/thoraxjnl-2014-206710
Studart Leitao Fernando Sergio, Hang Chen Hao, Ngan David A, Tam Anthony, Kirby Miranda, Sin Don D 2016. "Current methods to diagnose small airways disease in patients with COPD." Expert review of respiratory medicine doi:10.1586/17476348.2016.1155455
Luo Wei, Obeidat Ma'en, Di Narzo Antonio Fabio, Chen Rong, Sin Don D, et al. 2016. "Airway Epithelial Expression Quantitative Trait Loci Reveal Genes Underlying Asthma and Other Airway Diseases." American journal of respiratory cell and molecular biology 54 (2) doi:10.1165/rcmb.2014-0381OC
Adamson Simon L, Burns Jane, Camp Pat G, Sin Don D, van Eeden Stephan F 2016. "Impact of individualized care on readmissions after a hospitalization for acute exacerbation of COPD." International journal of chronic obstructive pulmonary disease 11 doi:10.2147/COPD.S93322
Park Hye Yun, Lee Hyun, Koh Won-Jung, Kim Seonwoo, Jeong Ina, et al. 2016. "Association of blood eosinophils and plasma periostin with FEV1 response after 3-month inhaled corticosteroid and long-acting beta2-agonist treatment in stable COPD patients." International journal of chronic obstructive pulmonary disease 11 doi:10.2147/COPD.S94797
Tam Anthony, Bates Jason H T, Churg Andrew, Wright Joanne L, Man S F Paul, Sin Don D 2016. "Sex-Related Differences in Pulmonary Function following 6 Months of Cigarette Exposure: Implications for Sexual Dimorphism in Mild COPD." PloS one 11 (10) doi:10.1371/journal.pone.0164835
Tan Wan C, Hague Cameron J, Leipsic Jonathon, Bourbeau Jean, Zheng Liyun, et al. 2016. "Findings on Thoracic Computed Tomography Scans and Respiratory Outcomes in Persons with and without Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study." PloS one 11 (11) doi:10.1371/journal.pone.0166745
Leung Janice M, Malagoli Andrea, Santoro Antonella, Besutti Giulia, Ligabue Guido, et al. 2016. "Emphysema Distribution and Diffusion Capacity Predict Emphysema Progression in Human Immunodeficiency Virus Infection." PloS one 11 (11) doi:10.1371/journal.pone.0167247
Chen Yu-Wei Roy, Leung Janice M, Sin Don D 2016. "A Systematic Review of Diagnostic Biomarkers of COPD Exacerbation." PloS one 11 (7) doi:10.1371/journal.pone.0158843
Leung Janice M, Chen Virginia, Hollander Zsuzsanna, Dai Darlene, Tebbutt Scott J, et al. 2016. "COPD Exacerbation Biomarkers Validated Using Multiple Reaction Monitoring Mass Spectrometry." PloS one 11 (8) doi:10.1371/journal.pone.0161129

2015

de Jong Kim, Vonk Judith M, Timens Wim, Bossé Yohan, Sin Don D, et al. 2015. "Genome-wide interaction study of gene-by-occupational exposure and effects on FEV1 levels." The Journal of allergy and clinical immunology 136 (6) doi:10.1016/j.jaci.2015.03.042
Kirby Miranda, Pike Damien, Sin Don D, Coxson Harvey O, McCormack David G, Parraga Grace 2015. "COPD: Do Imaging Measurements of Emphysema and Airway Disease Explain Symptoms and Exercise Capacity?" Radiology 277 (3) doi:10.1148/radiol.2015150037
Sin Don D, Hollander Zsuzsanna, DeMarco Mari L, McManus Bruce M, Ng Raymond T 2015. "Biomarker Development for Chronic Obstructive Pulmonary Disease. From Discovery to Clinical Implementation." American journal of respiratory and critical care medicine 192 (10) doi:10.1164/rccm.201505-0871PP
Saferali Aabida, Obeidat Ma'en, Bérubé Jean-Christophe, Lamontagne Maxime, Bossé Yohan, et al. 2015. "Polymorphisms associated with expression of BPIFA1/BPIFB1 and lung disease severity in cystic fibrosis." American journal of respiratory cell and molecular biology 53 (5) doi:10.1165/rcmb.2014-0182OC
Obeidat Ma'en, Hao Ke, Bossé Yohan, Nickle David C, Nie Yunlong, et al. 2015. "Molecular mechanisms underlying variations in lung function: a systems genetics analysis." The Lancet. Respiratory medicine 3 (10) doi:10.1016/S2213-2600(15)00380-X
Sze Marc A, Chen Yu-Wei Roy, Tam Sheena, Tashkin Donald, Wise Robert A, et al. 2015. "The relationship between Helicobacter pylori seropositivity and COPD." Thorax 70 (10) doi:10.1136/thoraxjnl-2015-207059
Khakban Amir, Sin Don D, FitzGerald J Mark, Ng Raymond, Zafari Zafar, et al. 2015. "Ten-Year Trends in Direct Costs of COPD: A Population-Based Study." Chest 148 (3) doi:10.1378/chest.15-0721
Sze Marc A, Dimitriu Pedro A, Suzuki Masaru, McDonough John E, Campbell Josh D, et al. 2015. "Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease." American journal of respiratory and critical care medicine 192 (4) doi:10.1164/rccm.201502-0223OC
Hansel Nadia N, Paré Peter D, Rafaels Nicholas, Sin Don D, Sandford Andrew, et al. 2015. "Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary Disease." American journal of respiratory cell and molecular biology 53 (2) doi:10.1165/rcmb.2014-0198OC
Oh Yeon-Mok, Jeong Byeong-Ho, Woo Sook-Young, Kim Su-Young, Kim Hojoong, et al. 2015. "Association of plasma adipokines with chronic obstructive pulmonary disease severity and progression." Annals of the American Thoracic Society 12 (7) doi:10.1513/AnnalsATS.201501-005OC
Apperley Scott, Park Hye Yun, Holmes Daniel T, Man S F Paul, Tashkin Donald, et al. 2015. "Serum Bilirubin and Disease Progression in Mild COPD." Chest 148 (1) doi:10.1378/chest.14-2150
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar A, et al. 2015. "An official American Thoracic Society/European Respiratory Society statement: research questions in COPD." European respiratory review : an official journal of the European Respiratory Society 24 (136) doi:10.1183/16000617.00000315
Soriano Joan B, Lamprecht Bernd, Ramírez Ana S, Martinez-Camblor Pablo, Kaiser Bernhard, et al. 2015. "Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2007 and 2011 staging systems: a pooled analysis of individual patient data." The Lancet. Respiratory medicine 3 (6) doi:10.1016/S2213-2600(15)00157-5
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar, et al. 2015. "An official American Thoracic Society/European Respiratory Society statement: research questions in COPD." The European respiratory journal 45 (4) doi:10.1183/09031936.00009015
Leung Janice M, Mayo John, Tan Wan, Tammemagi C Martin, Liu Geoffrey, et al. 2015. "Plasma pro-surfactant protein B and lung function decline in smokers." The European respiratory journal 45 (4) doi:10.1183/09031936.00184214
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar, et al. 2015. "An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 191 (7) doi:10.1164/rccm.201501-0044ST
Dijkstra Akkelies E, Postma Dirkje S, van Ginneken Bram, Wielpütz Mark O, Schmidt Michael, et al. 2015. "Novel genes for airway wall thickness identified with combined genome-wide association and expression analyses." American journal of respiratory and critical care medicine 191 (5) doi:10.1164/rccm.201405-0840OC
Poirier Julia G, Brennan Paul, McKay James D, Spitz Margaret R, Bickeböller Heike, et al. 2015. "Informed genome-wide association analysis with family history as a secondary phenotype identifies novel loci of lung cancer." Genetic epidemiology 39 (3) doi:10.1002/gepi.21882
Pike Damien, Kirby Miranda, Lindenmaier Tamas J, Sheikh Khadija, Neron Casey E, et al. 2015. "Pulmonary abnormalities and carotid atherosclerosis in ex-smokers without airflow limitation." COPD 12 (1) doi:10.3109/15412555.2014.908833
Leung Janice, Bhutani Mohit, Leigh Richard, Pelletier Dan, Good Cathy, Sin Don D 2015. "Empowering family physicians to impart proper inhaler teaching to patients with chronic obstructive pulmonary disease and asthma." Canadian respiratory journal : journal of the Canadian Thoracic Society 22 (5) doi:
Obeidat Ma'en, Fishbane Nick, Nie Yunlong, Chen Virginia, Hollander Zsuzsanna, et al. 2015. "The Effect of Statins on Blood Gene Expression in COPD." PloS one 10 (10) doi:10.1371/journal.pone.0140022
Soler Artigas María, Wain Louise V, Miller Suzanne, Kheirallah Abdul Kader, Huffman Jennifer E, et al. 2015. "Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation." Nature communications 6 doi:10.1038/ncomms9658
Lane Jérôme, van Eeden Stephan F, Obeidat Ma'en, Sin Don D, Tebbutt Scott J, et al. 2015. "Impact of Statins on Gene Expression in Human Lung Tissues." PloS one 10 (11) doi:10.1371/journal.pone.0142037
Wang Yu, Shumansky Karey, Sin Don D, Man Sf Paul, Akhabir Loubna, et al. 2015. "Associations of interleukin-1 gene cluster polymorphisms with C-reactive protein concentration and lung function decline in smoking-induced chronic obstructive pulmonary disease." International journal of clinical and experimental pathology 8 (10) doi:
Hirota Jeremy A, Gold Matthew J, Hiebert Paul R, Parkinson Leigh G, Wee Tracee, et al. 2015. "The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 μm." American journal of respiratory cell and molecular biology 52 (1) doi:10.1165/rcmb.2014-0158OC
Brandsma Corry-Anke, van den Berge Maarten, Postma Dirkje S, Jonker Marnix R, Brouwer Sharon, et al. 2015. "A large lung gene expression study identifying fibulin-5 as a novel player in tissue repair in COPD." Thorax 70 (1) doi:10.1136/thoraxjnl-2014-205091
Liu Joseph C Y, Leung Janice M, Ngan David A, Nashta Negar F, Guillemi Silvia, et al. 2015. "Absolute leukocyte telomere length in HIV-infected and uninfected individuals: evidence of accelerated cell senescence in HIV-associated chronic obstructive pulmonary disease." PloS one 10 (4) doi:10.1371/journal.pone.0124426

2014

Nguyen Justin Dang Uy, Lamontagne Maxime, Couture Christian, Conti Massimo, Paré Peter D, et al. 2014. "Susceptibility loci for lung cancer are associated with mRNA levels of nearby genes in the lung." Carcinogenesis 35 (12) doi:10.1093/carcin/bgu184
Hague Cameron J, Krowchuk Natasha, Alhassan Donya, Ho Kevin, Leipsic Jonathon, et al. 2014. "Qualitative and quantitative assessment of smoking-related lung disease: effect of iterative reconstruction on low-dose computed tomographic examinations." Journal of thoracic imaging 29 (6) doi:10.1097/RTI.0000000000000118
Lamontagne Maxime, Timens Wim, Hao Ke, Bossé Yohan, Laviolette Michel, et al. 2014. "Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction." Thorax 69 (11) doi:10.1136/thoraxjnl-2014-205630
Cressman Sonya, Lam Stephen, Tammemagi Martin C, Evans William K, Leighl Natasha B, et al. 2014. "Resource utilization and costs during the initial years of lung cancer screening with computed tomography in Canada." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 9 (10) doi:10.1097/JTO.0000000000000283
Hirota Jeremy A, Alexis Neil E, Pui Mandy, Wong SzeWing, Fung Elkie, et al. 2014. "PM10-stimulated airway epithelial cells activate primary human dendritic cells independent of uric acid: application of an in vitro model system exposing dendritic cells to airway epithelial cell-conditioned media." Respirology (Carlton, Vic.) 19 (6) doi:10.1111/resp.12316
Coxson Harvey O, Leipsic Jonathon, Parraga Grace, Sin Don D 2014. "Using pulmonary imaging to move chronic obstructive pulmonary disease beyond FEV1." American journal of respiratory and critical care medicine 190 (2) doi:10.1164/rccm.201402-0256PP
Criner Gerard J, Connett John E, Aaron Shawn D, Albert Richard K, Bailey William C, et al. 2014. "Simvastatin for the prevention of exacerbations in moderate-to-severe COPD." The New England journal of medicine 370 (23) doi:10.1056/NEJMoa1403086
Vucic Emily A, Chari Raj, Thu Kelsie L, Wilson Ian M, Cotton Allison M, et al. 2014. "DNA methylation is globally disrupted and associated with expression changes in chronic obstructive pulmonary disease small airways." American journal of respiratory cell and molecular biology 50 (5) doi:10.1165/rcmb.2013-0304OC
Wain Louise V, Sayers Ian, Soler Artigas María, Portelli Michael A, Zeggini Eleftheria, et al. 2014. "Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction." PLoS genetics 10 (5) doi:10.1371/journal.pgen.1004314
Leung Janice M, Liu Joseph C, Mtambo Andy, Ngan David, Nashta Negar, et al. 2014. "The determinants of poor respiratory health status in adults living with human immunodeficiency virus infection." AIDS patient care and STDs 28 (5) doi:10.1089/apc.2013.0373
Camp Pat G, Ramirez-Venegas Alejandra, Sansores Raul H, Alva Luis F, McDougall Jill E, et al. 2014. "COPD phenotypes in biomass smoke- versus tobacco smoke-exposed Mexican women." The European respiratory journal 43 (3) doi:10.1183/09031936.00206112
Agusti Alvar, Sin Don D 2014. "Biomarkers in COPD." Clinics in chest medicine 35 (1) doi:10.1016/j.ccm.2013.09.006
Zona Stefano, Santoro Antonella, Besutti Giulia, Ligabue Guido, Mussini Cristina, et al. 2014. "Burden of subclinical heart and lung disease detected on thoracic CT scans of HIV patients on HAART." Journal of the International AIDS Society 17 (4 Suppl 3) doi:
Guaraldi Giovanni, Besutti Giulia, Scaglioni Riccardo, Santoro Antonella, Zona Stefano, et al. 2014. "The burden of image based emphysema and bronchiolitis in HIV-infected individuals on antiretroviral therapy." PloS one 9 (10) doi:10.1371/journal.pone.0109027
Sze Marc A, Tsuruta Masashi, Yang Shun-Wei Julia, Oh Yeni, Man S F Paul, et al. 2014. "Changes in the bacterial microbiota in gut, blood, and lungs following acute LPS instillation into mice lungs." PloS one 9 (10) doi:10.1371/journal.pone.0111228
Stepaniants Sergey, Wang I-Ming, Boie Yves, Mortimer James, Kennedy Brian, et al. 2014. "Genes related to emphysema are enriched for ubiquitination pathways." BMC pulmonary medicine 14 doi:10.1186/1471-2466-14-187
Sze Marc A, Abbasi Meysam, Hogg James C, Sin Don D 2014. "A comparison between droplet digital and quantitative PCR in the analysis of bacterial 16S load in lung tissue samples from control and COPD GOLD 2." PloS one 9 (10) doi:10.1371/journal.pone.0110351
Sze Marc, Dimitriu Pedro A, Suzuki Masaru, McDonough John E, Gosselink John V, et al. 2014. "Host response to the lung microbiome in lung tissue undergoing emphysematous destruction." Annals of the American Thoracic Society 11 Suppl 1 doi:10.1513/AnnalsATS.201306-198MG
Sze Marc A, Hogg James C, Sin Don D 2014. "Bacterial microbiome of lungs in COPD." International journal of chronic obstructive pulmonary disease 9 doi:10.2147/COPD.S38932
Quon Bradley S, Ngan David A, Wilcox Pearce G, Man S F Paul, Sin Don D 2014. "Plasma sCD14 as a biomarker to predict pulmonary exacerbations in cystic fibrosis." PloS one 9 (2) doi:10.1371/journal.pone.0089341
Saferali Aabida, Lee Jee, Sin Don D, Rouhani Farshid N, Brantly Mark L, Sandford Andrew J 2014. "Longer telomere length in COPD patients with α1-antitrypsin deficiency independent of lung function." PloS one 9 (4) doi:10.1371/journal.pone.0095600
Tam Anthony, Wadsworth Samuel, Dorscheid Delbert, Man Shu-Fan Paul, Sin Don D 2014. "Estradiol increases mucus synthesis in bronchial epithelial cells." PloS one 9 (6) doi:10.1371/journal.pone.0100633

2013

Sin Don D, Tammemagi C Martin, Lam Stephen, Barnett Matt J, Duan Xiaobo, et al. 2013. "Pro-surfactant protein B as a biomarker for lung cancer prediction." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 31 (36) doi:10.1200/JCO.2013.50.6105
Park Hye Yun, Churg Andrew, Wright Joanne L, Li Yuexin, Tam Sheena, et al. 2013. "Club cell protein 16 and disease progression in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 188 (12) doi:10.1164/rccm.201305-0892OC
Hakimi Shoki Alborz, Mayer-Hamblett Nicole, Wilcox Pearce G, Sin Don D, Quon Bradley S 2013. "Systematic Review of Blood Biomarkers in Cystic Fibrosis Pulmonary Exacerbations." Chest doi:10.1378/chest.13-0693
Miyata Ryohei, Hiraiwa Kunihiko, Cheng Jui Chih, Bai Ni, Vincent Renaud, et al. 2013. "Statins attenuate the development of atherosclerosis and endothelial dysfunction induced by exposure to urban particulate matter (PM10)." Toxicology and applied pharmacology doi:10.1016/j.taap.2013.05.033
Sayiner Abdullah, Hague Cameron, Ajlan Amr, Leipsic Jonathon, Wierenga Lauren, et al. 2013. "Bronchiolitis in young female smokers." Respiratory medicine 107 (5) doi:10.1016/j.rmed.2012.12.023
Kim Won-Dong, Chi Hyun-Sook, Choe Kang-Hyeon, Oh Yeon-Mok, Lee Sang-Do, et al. 2013. "A possible role for CD8+ and non-CD8+ cell granzyme B in early small airway wall remodelling in centrilobular emphysema." Respirology (Carlton, Vic.) 18 (4) doi:10.1111/resp.12069
Vestbo Jørgen, Hurd Suzanne S, Agustí Alvar G, Jones Paul W, Vogelmeier Claus, et al. 2013. "Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary." American journal of respiratory and critical care medicine 187 (4) doi:10.1164/rccm.201204-0596PP
Aaron Shawn D, Vandemheen Katherine L, Maltais François, Field Stephen K, Sin Don D, et al. 2013. "TNFα antagonists for acute exacerbations of COPD: a randomised double-blind controlled trial." Thorax 68 (2) doi:10.1136/thoraxjnl-2012-202432
Miyata Ryohei, Bai Ni, Vincent Renaud, Sin Don D, Van Eeden Stephan F 2013. "Statins reduce ambient particulate matter-induced lung inflammation by promoting the clearance of particulate matter, < 10 μm from lung tissues." Chest 143 (2) doi:10.1378/chest.12-1237
Winstone Tiffany A, Man S F Paul, Hull Mark, Montaner Julio S, Sin Don D 2013. "Epidemic of lung cancer in patients with HIV infection." Chest 143 (2) doi:10.1378/chest.12-1699
Hansel Nadia N, Ruczinski Ingo, Rafaels Nicholas, Sin Don D, Daley Denise, et al. 2013. "Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD." Human genetics 132 (1) doi:10.1007/s00439-012-1219-6
Tan Wan C, Bourbeau Jean, Hernandez Paul, Chapman Kenneth R, Cowie Robert, et al. 2013. "Bronchodilator responsiveness and reported respiratory symptoms in an adult population." PloS one 8 (3) doi:10.1371/journal.pone.0058932
Zhou Steven, Wright Joanne L, Liu Joseph, Sin Don D, Churg Andrew 2013. "Aging does not enhance experimental cigarette smoke-induced COPD in the mouse." PloS one 8 (8) doi:10.1371/journal.pone.0071410
Lamontagne Maxime, Couture Christian, Postma Dirkje S, Timens Wim, Sin Don D, et al. 2013. "Refining susceptibility loci of chronic obstructive pulmonary disease with lung eqtls." PloS one 8 (7) doi:10.1371/journal.pone.0070220
Um Soo Jung, Lam Stephen, Coxson Harvey, Man Shu Fan Paul, Sin Don D 2013. "Budesonide/formoterol enhances the expression of pro Surfactant Protein-B in lungs of COPD patients." PloS one 8 (12) doi:10.1371/journal.pone.0083881
Hui Phillip, Mattman Andre, Wilcox Pearce G, Wright Joanne L, Sin Don D 2013. "Immunoglobulin G4-related lung disease: a disease with many different faces." Canadian respiratory journal : journal of the Canadian Thoracic Society 20 (5) doi:
Park Hye Yun, Man S F Paul, Tashkin Donald, Wise Robert A, Connett John E, et al. 2013. "The Relation of Serum Myeloperoxidase to Disease Progression and Mortality in Patients with Chronic Obstructive Pulmonary Disease (COPD)." PloS one 8 (4) doi:10.1371/journal.pone.0061315

2012

Lee Hwa Mu, Lee Janet, Lee Katherine, Luo Yanting, Sin Don D, Wong Nathan D 2012. "Relation between COPD severity and global cardiovascular risk in US adults." Chest 142 (5) doi:10.1378/chest.11-2421
Yoon Ho Il, Li Yuexin, Man S F Paul, Tashkin Donald, Wise Robert A, et al. 2012. "The complex relationship of serum adiponectin to COPD outcomes COPD and adiponectin." Chest 142 (4) doi:10.1378/chest.11-2173
Miyata Ryohei, Bai Ni, Vincent Renaud, Sin Don D, Van Eeden Stephan F 2012. "Novel properties of statins: suppression of the systemic and bone marrow responses induced by exposure to ambient particulate matter (PM(10)) air pollution." American journal of physiology. Lung cellular and molecular physiology 303 (6) doi:10.1152/ajplung.00154.2012
Bossé Yohan, Postma Dirkje S, Sin Don D, Lamontagne Maxime, Couture Christian, et al. 2012. "Molecular signature of smoking in human lung tissues." Cancer research 72 (15) doi:10.1158/0008-5472.CAN-12-1160
Tam Anthony, Sin Don D 2012. "Pathobiologic mechanisms of chronic obstructive pulmonary disease." The Medical clinics of North America 96 (4) doi:10.1016/j.mcna.2012.04.012
Van Eeden Stephan, Leipsic Jonathon, Paul Man S F, Sin Don D 2012. "The relationship between lung inflammation and cardiovascular disease." American journal of respiratory and critical care medicine 186 (1) doi:10.1164/rccm.201203-0455PP
Sze Marc A, Dimitriu Pedro A, Hayashi Shizu, Elliott W Mark, McDonough John E, et al. 2012. "The lung tissue microbiome in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 185 (10) doi:10.1164/rccm.201111-2075OC
Zurawska Joanna H, Jen Rachel, Lam Stephen, Coxson Harvey O, Leipsic Jonathon, Sin Don D 2012. "What to do when a smoker's CT scan is "normal"?: Implications for lung cancer screening." Chest 141 (5) doi:10.1378/chest.11-1863
Hirota Jeremy A, Hirota Simon A, Warner Stephanie M, Stefanowicz Dorota, Shaheen Furquan, et al. 2012. "The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter." The Journal of allergy and clinical immunology 129 (4) doi:10.1016/j.jaci.2011.11.033
Jaw Jen Erh, Sin Don D 2012. "Unifying thoracic biomarkers: surfactant protein-D and beyond." Expert review of respiratory medicine 6 (2) doi:10.1586/ers.12.5
Bourbeau Jean, Tan Wan C, Benedetti Andrea, Aaron Shawn D, Chapman Kenneth R, et al. 2012. "Canadian Cohort Obstructive Lung Disease (CanCOLD): Fulfilling the Need for Longitudinal Observational Studies in COPD." COPD doi:10.3109/15412555.2012.665520
Churg Andrew, Marshall Caroline V, Sin Don D, Bolton Sarah, Zhou Steven, et al. 2012. "Late intervention with a myeloperoxidase inhibitor stops progression of experimental chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 185 (1) doi:10.1164/rccm.201103-0468OC
Oh Jin Young, Sin Don D 2012. "Lung inflammation in COPD: why does it matter?" F1000 medicine reports 4 doi:10.3410/M4-23
Hao Ke, Bossé Yohan, Nickle David C, Paré Peter D, Postma Dirkje S, et al. 2012. "Lung eQTLs to help reveal the molecular underpinnings of asthma." PLoS genetics 8 (11) doi:10.1371/journal.pgen.1003029
Shakoori Tania A, Sin Don D, Bokhari S Nazim Hussain, Ghafoor Farkhanda, Shakoori A R 2012. "SP-D polymorphisms and the risk of COPD." Disease markers 33 (2) doi:10.3233/DMA-2012-0909
Jen Rachel, Rennard Stephen I, Sin Don D 2012. "Effects of inhaled corticosteroids on airway inflammation in chronic obstructive pulmonary disease: a systematic review and meta-analysis." International journal of chronic obstructive pulmonary disease 7 doi:10.2147/COPD.S32765
Man S F Paul, Van Eeden Stephan, Sin Don D 2012. "Vascular risk in chronic obstructive pulmonary disease: role of inflammation and other mediators." The Canadian journal of cardiology 28 (6) doi:10.1016/j.cjca.2012.06.013
Ngan David A, Wilcox Pearce G, Aldaabil May, Li Yuexin, Leipsic Jonathon A, et al. 2012. "The relationship of systemic inflammation to prior hospitalization in adult patients with cystic fibrosis." BMC pulmonary medicine 12 doi:10.1186/1471-2466-12-3
Lee Jee, Sandford Andrew J, Connett John E, Yan Jin, Mui Tammy, et al. 2012. "The relationship between telomere length and mortality in chronic obstructive pulmonary disease (COPD)." PloS one 7 (4) doi:10.1371/journal.pone.0035567

2011

Churg Andrew, Sin Don D, Wright Joanne L 2011. "Everything prevents emphysema: are animal models of cigarette smoke-induced chronic obstructive pulmonary disease any use?" American journal of respiratory cell and molecular biology 45 (6) doi:10.1165/rcmb.2011-0087PS
McDonough John E, Yuan Ren, Suzuki Masaru, Seyednejad Nazgol, Elliott W Mark, et al. 2011. "Small-airway obstruction and emphysema in chronic obstructive pulmonary disease." The New England journal of medicine 365 (17) doi:10.1056/NEJMoa1106955
Suda Koichi, Eom Jihyoun, Jaw Jen-Erh, Mui Tammy, Bai Ni, et al. 2011. "Endotoxin-induced cardiovascular dysfunction in mice: effect of simvastatin." Journal of applied physiology (Bethesda, Md. : 1985) 111 (4) doi:10.1152/japplphysiol.00158.2011
Yoon Ho Il, Sin Don D 2011. "Biomarkers of therapeutic response in patients with chronic obstructive pulmonary disease: a critical review of the literature." Drugs 71 (14) doi:10.2165/11595180-000000000-00000
Suda Koichi, Tsuruta Masashi, Eom Jihyoun, Or Chris, Mui Tammy, et al. 2011. "Acute lung injury induces cardiovascular dysfunction: effects of IL-6 and budesonide/formoterol." American journal of respiratory cell and molecular biology 45 (3) doi:10.1165/rcmb.2010-0169OC
van Lier Felix, van der Geest Patrick J, Hoeks Sanne E, van Gestel Yvette R B M, Hol Jaap W, et al. 2011. "Epidural analgesia is associated with improved health outcomes of surgical patients with chronic obstructive pulmonary disease." Anesthesiology 115 (2) doi:10.1097/ALN.0b013e318224cc5c
Hill John, Heslop Claire, Man S F Paul, Frohlich Jiri, Connett John E, et al. 2011. "Circulating surfactant protein-D and the risk of cardiovascular morbidity and mortality." European heart journal 32 (15) doi:10.1093/eurheartj/ehr124
Tam Anthony, Wadsworth Samuel, Dorscheid Delbert, Man S F Paul, Sin Don D 2011. "The airway epithelium: more than just a structural barrier." Therapeutic advances in respiratory disease 5 (4) doi:10.1177/1753465810396539
Sin Don D, Miller Bruce E, Duvoix Annelyse, Man S F Paul, Zhang Xuekui, et al. 2011. "Serum PARC/CCL-18 concentrations and health outcomes in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 183 (9) doi:10.1164/rccm.201008-1220OC
Tammemagi Martin C, Lam Stephen C, McWilliams Annette M, Sin Don D 2011. "Incremental value of pulmonary function and sputum DNA image cytometry in lung cancer risk prediction." Cancer prevention research (Philadelphia, Pa.) 4 (4) doi:10.1158/1940-6207.CAPR-10-0183
Lee Jee, Sandford Andrew, Man Paul, Sin Don D 2011. "Is the aging process accelerated in chronic obstructive pulmonary disease?" Current opinion in pulmonary medicine 17 (2) doi:
Kido Takashi, Tamagawa Eiji, Bai Ni, Suda Koichi, Yang Huei-Hsin C, et al. 2011. "Particulate matter induces translocation of IL-6 from the lung to the systemic circulation." American journal of respiratory cell and molecular biology 44 (2) doi:10.1165/rcmb.2009-0427OC
Wu Jane, Sin Don D 2011. "Improved patient outcome with smoking cessation: when is it too late?" International journal of chronic obstructive pulmonary disease 6 doi:10.2147/COPD.S10771
Hackett Tillie-Louise, Stefanowicz Dorota, Aminuddin Farzian, Sin Don D, Connett John E, et al. 2011. "Effect of gene environment interactions on lung function and cardiovascular disease in COPD." International journal of chronic obstructive pulmonary disease 6 doi:10.2147/COPD.S18279
Tam Anthony, Morrish Don, Wadsworth Samuel, Dorscheid Delbert, Man S F Paul, Sin Don D 2011. "The role of female hormones on lung function in chronic lung diseases." BMC women's health 11 doi:10.1186/1472-6874-11-24
Wright Joanne L, Zhou Steven, Preobrazhenska Olena, Marshall Caroline, Sin Don D, et al. 2011. "Statin reverses smoke-induced pulmonary hypertension and prevents emphysema but not airway remodeling." American journal of respiratory and critical care medicine 183 (1) doi:10.1164/rccm.201003-0399OC
Coxson Harvey O, Eastwood Peter R, Williamson Jonathan P, Sin Don D 2011. "Phenotyping airway disease with optical coherence tomography." Respirology (Carlton, Vic.) 16 (1) doi:10.1111/j.1440-1843.2010.01888.x

2010

Tkacova Ruzena, McWilliams Annette, Lam Stephen, Sin Don D 2010. "Integrating lung and plasma expression of pneumo-proteins in developing biomarkers in COPD: a case study of surfactant protein D." Medical science monitor : international medical journal of experimental and clinical research 16 (11) doi:
van Gestel Yvette R B M, Flu Willem-Jan, van Kuijk Jan-Peter, Hoeks Sanne E, Bax Jeroen J, et al. 2010. "Association of COPD with carotid wall intima-media thickness in vascular surgery patients." Respiratory medicine 104 (5) doi:10.1016/j.rmed.2009.10.027
Flu Willem-Jan, van Gestel Yvette R B M, van Kuijk Jan-Peter, Hoeks Sanne E, Kuiper Ruud, et al. 2010. "Co-existence of COPD and left ventricular dysfunction in vascular surgery patients." Respiratory medicine 104 (5) doi:10.1016/j.rmed.2009.11.013
van Gestel Yvette R B M, Goei Dustin, Hoeks Sanne E, Sin Don D, Flu Willem-Jan, et al. 2010. "Predictive value of NT-proBNP in vascular surgery patients with COPD and normal left ventricular systolic function." COPD 7 (1) doi:10.3109/15412550903499472
Rizkallah Jacques, Sin Don D 2010. "Integrative approach to quality assessment of medical journals using impact factor, eigenfactor, and article influence scores." PloS one 5 (4) doi:10.1371/journal.pone.0010204
Kliber Agnes, Lynd Larry D, Sin Don D 2010. "The effects of long-acting bronchodilators on total mortality in patients with stable chronic obstructive pulmonary disease." Respiratory research 11 doi:10.1186/1465-9921-11-56
Hackett Tillie L, Knight Darryl A, Sin Don D 2010. "Potential role of stem cells in management of COPD." International journal of chronic obstructive pulmonary disease 5 doi:
Ryerson Christopher J, Nayar Shalini, Swiston John R, Sin Don D 2010. "Pharmacotherapy in pulmonary arterial hypertension: a systematic review and meta-analysis." Respiratory research 11 doi:10.1186/1465-9921-11-12
Yuan Ren, Nagao Taishi, Paré Peter D, Hogg James C, Sin Don D, et al. 2010. "Quantification of lung surface area using computed tomography." Respiratory research 11 doi:10.1186/1465-9921-11-153

2009

Churg Andrew, Sin Don D, Everett Douglas, Brown Kevin, Cool Carlyne 2009. "Pathologic patterns and survival in chronic hypersensitivity pneumonitis." The American journal of surgical pathology 33 (12) doi:10.1097/PAS.0b013e3181bb2538
Coxson Harvey O, Mayo John, Lam Stephen, Santyr Giles, Parraga Grace, Sin Don D 2009. "New and current clinical imaging techniques to study chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 180 (7) doi:10.1164/rccm.200901-0159PP
Sin Don D, Vestbo Jørgen 2009. "Biomarkers in chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 6 (6) doi:10.1513/pats.200904-019DS
Sin Don D, Tashkin Donald, Zhang Xuekui, Radner Finn, Sjöbring Ulf, et al. 2009. "Budesonide and the risk of pneumonia: a meta-analysis of individual patient data." Lancet 374 (9691) doi:10.1016/S0140-6736(09)61250-2
Tamagawa Eiji, Suda Koichi, Wei Yuan, Xing Li, Mui Tammy, et al. 2009. "Endotoxin-induced translocation of interleukin-6 from lungs to the systemic circulation." Innate immunity 15 (4) doi:10.1177/1753425909104782
Yee John, Sadar Marianne D, Sin Don D, Kuzyk Michael, Xing Li, et al. 2009. "Connective tissue-activating peptide III: a novel blood biomarker for early lung cancer detection." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27 (17) doi:10.1200/JCO.2008.19.4233
Ngan David A, Vickerman Shawna V, Granville David J, Man S F Paul, Sin Don D 2009. "The possible role of granzyme B in the pathogenesis of chronic obstructive pulmonary disease." Therapeutic advances in respiratory disease 3 (3) doi:10.1177/1753465809341965
Tan Wan C, Lo Christine, Jong Aimee, Xing Li, Fitzgerald Mark J, et al. 2009. "Marijuana and chronic obstructive lung disease: a population-based study." CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 180 (8) doi:10.1503/cmaj.081040
Man S F Paul, Xuekui Zhang, Vessey Rupert, Walker Terry, Lee Kwan, et al. 2009. "The effects of inhaled and oral corticosteroids on serum inflammatory biomarkers in COPD: an exploratory study." Therapeutic advances in respiratory disease 3 (2) doi:10.1177/1753465809336697
Rizkallah Jacques, Man S F Paul, Sin Don D 2009. "Prevalence of pulmonary embolism in acute exacerbations of COPD: a systematic review and metaanalysis." Chest 135 (3) doi:10.1378/chest.08-1516
van Gestel Yvette R B M, Hoeks Sanne E, Sin Don D, Stam Henk, Mertens Frans W, et al. 2009. "Beta-blockers and health-related quality of life in patients with peripheral arterial disease and COPD." International journal of chronic obstructive pulmonary disease 4 doi:
Shakoori Tania Ahmed, Sin Don D, Ghafoor Farkhanda, Bashir Saira, Bokhari S Nazim Hussain 2009. "Serum surfactant protein D during acute exacerbations of chronic obstructive pulmonary disease." Disease markers 27 (6) doi:10.3233/DMA-2009-0674

2008

Galal Wael, van Gestel Yvette R B M, Hoeks Sanne E, Sin Don D, Winkel Tamara A, et al. 2008. "The obesity paradox in patients with peripheral arterial disease." Chest 134 (5) doi:10.1378/chest.08-0418
Wong Alyson W M, Gan Wen Q, Burns Jane, Sin Don D, van Eeden Sephan F 2008. "Acute exacerbation of chronic obstructive pulmonary disease: influence of social factors in determining length of hospital stay and readmission rates." Canadian respiratory journal : journal of the Canadian Thoracic Society 15 (7) doi:
van Gestel Yvette R B M, Hoeks Sanne E, Sin Don D, Welten Gijs M J M, Schouten Olaf, et al. 2008. "Impact of cardioselective beta-blockers on mortality in patients with chronic obstructive pulmonary disease and atherosclerosis." American journal of respiratory and critical care medicine 178 (7) doi:10.1164/rccm.200803-384OC
Sin Don D, Man S F Paul, McWilliams Annette, Lam Stephen 2008. "Surfactant protein D and bronchial dysplasia in smokers at high risk of lung cancer." Chest 134 (3) doi:10.1378/chest.08-0600
Gan Wen Qi, Cohen Sigal Ben-Zaken, Man S F Paul, Sin Don D 2008. "Sex-related differences in serum cotinine concentrations in daily cigarette smokers." Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 10 (8) doi:10.1080/14622200802239132
van Gestel Yvette R B M, Hoeks Sanne E, Sin Don D, Simsek Cihan, Welten Gijs M J M, et al. 2008. "Effect of statin therapy on mortality in patients with peripheral arterial disease and comparison of those with versus without associated chronic obstructive pulmonary disease." The American journal of cardiology 102 (2) doi:10.1016/j.amjcard.2008.03.038
Tamagawa Eiji, Bai Ni, Morimoto Kiyoshi, Gray Claire, Mui Tammy, et al. 2008. "Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction." American journal of physiology. Lung cellular and molecular physiology 295 (1) doi:10.1152/ajplung.00048.2007
Coxson Harvey O, Quiney Brendan, Sin Don D, Xing Li, McWilliams Annette M, et al. 2008. "Airway wall thickness assessed using computed tomography and optical coherence tomography." American journal of respiratory and critical care medicine 177 (11) doi:10.1164/rccm.200712-1776OC
Sin Don D, Man S F Paul, Marciniuk Darcy D, Ford Gordon, FitzGerald Mark, et al. 2008. "The effects of fluticasone with or without salmeterol on systemic biomarkers of inflammation in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 177 (11) doi:10.1164/rccm.200709-1356OC
Mui Tammy Sy, Man Sf Paul, Sin Don D 2008. "Developments in drugs for the treatment of chronic obstructive pulmonary disease." Expert review of clinical immunology 4 (3) doi:10.1586/1744666X.4.3.365
Sin Don D, Pahlavan Payam S, Man S F Paul 2008. "Surfactant protein D: a lung specific biomarker in COPD?" Therapeutic advances in respiratory disease 2 (2) doi:10.1177/1753465808088903
Quon Bradley S, Gan Wen Qi, Sin Don D 2008. "Contemporary management of acute exacerbations of COPD: a systematic review and metaanalysis." Chest 133 (3) doi:10.1378/chest.07-1207
Sin Don D, Man S F Paul 2008. "Impact of cancers and cardiovascular diseases in chronic obstructive pulmonary disease." Current opinion in pulmonary medicine 14 (2) doi:10.1097/MCP.0b013e3282f45ffb
Briggs Andrew, Spencer Michael, Wang Hong, Mannino David, Sin Don D 2008. "Development and validation of a prognostic index for health outcomes in chronic obstructive pulmonary disease." Archives of internal medicine 168 (1) doi:10.1001/archinternmed.2007.37
van Eeden Stephan F, Sin Don D 2008. "Chronic obstructive pulmonary disease: a chronic systemic inflammatory disease." Respiration; international review of thoracic diseases 75 (2) doi:10.1159/000111820
Chee Alex, Sin Don D 2008. "Treatment of mild chronic obstructive pulmonary disease." International journal of chronic obstructive pulmonary disease 3 (4) doi:

2007

Sin Don D, Cohen Sigal Ben-Zaken, Day Anna, Coxson Harvey, Paré Peter D 2007. "Understanding the biological differences in susceptibility to chronic obstructive pulmonary disease between men and women." Proceedings of the American Thoracic Society 4 (8) doi:10.1513/pats.200706-082SD
Tkác Ján, Man S F Paul, Sin Don D 2007. "Systemic consequences of COPD." Therapeutic advances in respiratory disease 1 (1) doi:10.1177/1753465807082374
Hogg James C, Chu Fanny S F, Tan Wan C, Sin Don D, Patel Sanjay A, et al. 2007. "Survival after lung volume reduction in chronic obstructive pulmonary disease: insights from small airway pathology." American journal of respiratory and critical care medicine 176 (5) doi:10.1164/rccm.200612-1772OC
Ben-Zaken Cohen Sigal, Paré Peter D, Man S F Paul, Sin Don D 2007. "The growing burden of chronic obstructive pulmonary disease and lung cancer in women: examining sex differences in cigarette smoke metabolism." American journal of respiratory and critical care medicine 176 (2) doi:10.1164/rccm.200611-1655PP
Soriano Joan B, Sin Don D, Zhang Xuekui, Camp Pat G, Anderson Julie A, et al. 2007. "A pooled analysis of FEV1 decline in COPD patients randomized to inhaled corticosteroids or placebo." Chest 131 (3) doi:10.1378/chest.06-1696
Sin Don D, Man S F Paul 2007. "Do chronic inhaled steroids alone or in combination with a bronchodilator prolong life in chronic obstructive pulmonary disease patients?" Current opinion in pulmonary medicine 13 (2) doi:10.1097/MCP.0b013e3280142021
Sin Don D, Man S F Paul 2007. "Systemic inflammation and mortality in chronic obstructive pulmonary disease." Canadian journal of physiology and pharmacology 85 (1) doi:10.1139/y06-093
Yerman Todd, Gan Wen Q, Sin Don D 2007. "The influence of gender on the effects of aspirin in preventing myocardial infarction." BMC medicine 5 doi:10.1186/1741-7015-5-29
Sin Don D, Leung Rochelle, Gan Wen Q, Man Sf Paul 2007. "Circulating surfactant protein D as a potential lung-specific biomarker of health outcomes in COPD: a pilot study." BMC pulmonary medicine 7 doi:10.1186/1471-2466-7-13
Sin Don D, Wong Eric, Mayers Irvin, Lien Dale C, Feeny David, et al. 2007. "Effects of nocturnal noninvasive mechanical ventilation on heart rate variability of patients with advanced COPD." Chest 131 (1) doi:10.1378/chest.06-1423

2006

Sin Don D, Man S F Paul 2006. "Pharmacotherapy for mortality reduction in chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 3 (7) doi:10.1513/pats.200603-096SS
Cowie Robert L, Underwood Margot F, Sin Don D, Sharpe Heather M, Bell Neil R, Man S F Paul 2006. "Asthma control and management in the community: indices in 1997 compared with indices in 2002." Canadian family physician Médecin de famille canadien 52 doi:
Malhotra Samir, Man S F Paul, Sin Don D 2006. "Emerging drugs for the treatment of chronic obstructive pulmonary disease." Expert opinion on emerging drugs 11 (2) doi:10.1517/14728214.11.2.275
Sin Don D, Man S F Paul 2006. "Corticosteroids and adrenoceptor agonists: the compliments for combination therapy in chronic airways diseases." European journal of pharmacology 533 (1-3) doi:10.1016/j.ejphar.2005.12.049
Sin Don D, Man S F Paul, McWilliams Annette, Lam Stephen 2006. "Progression of airway dysplasia and C-reactive protein in smokers at high risk of lung cancer." American journal of respiratory and critical care medicine 173 (5) doi:10.1164/rccm.200508-1305OC
de Jong Pim A, Mayo John R, Golmohammadi Kamran, Nakano Yasutaka, Lequin Maarten H, et al. 2006. "Estimation of cancer mortality associated with repetitive computed tomography scanning." American journal of respiratory and critical care medicine 173 (2) doi:10.1164/rccm.200505-810OC
Sin Don D, Man S F Paul, Marciniuk Darcy D, Ford Gordon, FitzGerald Mark, et al. 2006. "Can inhaled fluticasone alone or in combination with salmeterol reduce systemic inflammation in chronic obstructive pulmonary disease? Study protocol for a randomized controlled trial [NCT00120978]." BMC pulmonary medicine 6 doi:10.1186/1471-2466-6-3
Malhotra Samir, Lam Stephen, Man S F Paul, Gan Wen Q, Sin Don D 2006. "The relationship between stage 1 and 2 non-small cell lung cancer and lung function in men and women." BMC pulmonary medicine 6 doi:10.1186/1471-2466-6-2
Gan Wen Qi, Man S F Paul, Postma Dirkje S, Camp Patricia, Sin Don D 2006. "Female smokers beyond the perimenopausal period are at increased risk of chronic obstructive pulmonary disease: a systematic review and meta-analysis." Respiratory research 7 doi:10.1186/1465-9921-7-52

2005

Borszcz Peter D, Befus Dean, Moqbel Redwan, Sin Don D, Adamko Darryl J, et al. 2005. "Effects of clarithromycin on inflammatory cell mediator release and survival." Chemotherapy 51 (4) doi:10.1159/000086922
Sin Don D, Wu LieLing, Man S F Paul 2005. "The relationship between reduced lung function and cardiovascular mortality: a population-based study and a systematic review of the literature." Chest 127 (6) doi:10.1378/chest.127.6.1952
Tsuyuki Ross T, Sin Don D, Sharpe Heather M, Cowie Robert L, Nilsson Carolyn, Man S F Paul 2005. "Management of asthma among community-based primary care physicians." The Journal of asthma : official journal of the Association for the Care of Asthma 42 (3) doi:
Sin Don D, Man S F Paul, Marrie Thomas J 2005. "Arterial carbon dioxide tension on admission as a marker of in-hospital mortality in community-acquired pneumonia." The American journal of medicine 118 (2) doi:10.1016/j.amjmed.2004.10.014
Gan Wen Qi, Man S F Paul, Sin Don D 2005. "The interactions between cigarette smoking and reduced lung function on systemic inflammation." Chest 127 (2) doi:10.1378/chest.127.2.558
Sin Don D, Man S F Paul 2005. "Chronic obstructive pulmonary disease as a risk factor for cardiovascular morbidity and mortality." Proceedings of the American Thoracic Society 2 (1) doi:10.1513/pats.200404-032MS
Gan Wen Qi, Man S F Paul, Sin Don D 2005. "Effects of inhaled corticosteroids on sputum cell counts in stable chronic obstructive pulmonary disease: a systematic review and a meta-analysis." BMC pulmonary medicine 5 doi:10.1186/1471-2466-5-3
Sin Don D, Man S F Paul 2005. "Chronic obstructive pulmonary disease: a novel risk factor for cardiovascular disease." Canadian journal of physiology and pharmacology 83 (1) doi:10.1139/y04-116
Man S F Paul, Sin Don D 2005. "Inhaled corticosteroids in chronic obstructive pulmonary disease: is there a clinical benefit?" Drugs 65 (5) doi:
Man S F Paul, Sin Don D 2005. "Effects of corticosteroids on systemic inflammation in chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 2 (1) doi:10.1513/pats.200406-034MS

2004

Sin Don D, Lacy Paige, York Ernest, Man S F Paul 2004. "Effects of fluticasone on systemic markers of inflammation in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 170 (7) doi:10.1164/rccm.200404-543OC
Sin Don D, Bell Neil R, Man S F Paul 2004. "Effects of increased primary care access on process of care and health outcomes among patients with asthma who frequent emergency departments." The American journal of medicine 117 (7) doi:10.1016/j.amjmed.2004.04.011
Sin Don D, Man Jonathan, Sharpe Heather, Gan Wen Qi, Man S F Paul 2004. "Pharmacological management to reduce exacerbations in adults with asthma: a systematic review and meta-analysis." JAMA : the journal of the American Medical Association 292 (3) doi:10.1001/jama.292.3.367
Sin Don D, Johnson Malcolm, Gan Wen Qi, Man S F Paul 2004. "Combination therapy of inhaled corticosteroids and long-acting beta2-adrenergics in management of patients with chronic obstructive pulmonary disease." Current pharmaceutical design 10 (28) doi:
Golmohammadi Kamran, Jacobs Philip, Sin Don D 2004. "Economic evaluation of a community-based pulmonary rehabilitation program for chronic obstructive pulmonary disease." Lung 182 (3) doi:
Sin Don D, Sharpe Heather M, Cowie Robert L, Man S F Paul 2004. "Spirometric findings among school-aged First Nations children on a reserve: a pilot study." Canadian respiratory journal : journal of the Canadian Thoracic Society 11 (1) doi:
Sin Don D, Spier Sheldon, Svenson Larry W, Schopflocher Don P, Senthilselvan Ambikaipakan, et al. 2004. "The relationship between birth weight and childhood asthma: a population-based cohort study." Archives of pediatrics & adolescent medicine 158 (1) doi:10.1001/archpedi.158.1.60
Corrigan Susan P, Cecillon David L, Sin Don D, Sharpe Heather M, Andrews Elaine M, et al. 2004. "The costs of implementing the 1999 Canadian Asthma Consensus Guidelines recommendation of asthma education and spirometry for the family physician." Canadian respiratory journal : journal of the Canadian Thoracic Society 11 (5) doi:
Sharpe Heather M, Sin Don D, Andrews Elaine M, Cowie Robert L, Man Paul 2004. "Alberta Strategy to Help Manage Asthma (ASTHMA): a provincial initiative to improve outcomes for individuals with asthma." Healthcare quarterly (Toronto, Ont.) 7 (3) doi:
Man Jonathan P, Weinkauf Justin G, Tsang Monica, Sin Don D 2004. "Why do some countries publish more than others? An international comparison of research funding, English proficiency and publication output in highly ranked general medical journals." European journal of epidemiology 19 (8) doi:

2003

Sin Don D, McAlister Finlay A, Man S F Paul, Anthonisen Nick R 2003. "Contemporary management of chronic obstructive pulmonary disease: scientific review." JAMA : the journal of the American Medical Association 290 (17) doi:10.1001/jama.290.17.2301
Man S F Paul, McAlister Finlay A, Anthonisen Nick R, Sin Don D 2003. "Contemporary management of chronic obstructive pulmonary disease: clinical applications." JAMA : the journal of the American Medical Association 290 (17) doi:10.1001/jama.290.17.2313
Sin Don D, Svenson Larry W, Cowie Robert L, Man S F Paul 2003. "Can universal access to health care eliminate health inequities between children of poor and nonpoor families?: A case study of childhood asthma in Alberta." Chest 124 (1) doi:
Sin Don D, Fitzgerald Fabia, Parker John D, Newton Gary E, Logan Alexander G, et al. 2003. "Relationship of systolic BP to obstructive sleep apnea in patients with heart failure." Chest 123 (5) doi:
Sin Don D, Man S F Paul 2003. "Why are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular diseases? The potential role of systemic inflammation in chronic obstructive pulmonary disease." Circulation 107 (11) doi:
Sin Don D, Man Jonathan P, Man S F Paul 2003. "The risk of osteoporosis in Caucasian men and women with obstructive airways disease." The American journal of medicine 114 (1) doi:
Sin Don D, Man S F Paul 2003. "Inhaled corticosteroids in the long-term management of patients with chronic obstructive pulmonary disease." Drugs & aging 20 (12) doi:

2002

Sin Don D, McAlister Finlay A 2002. "The effects of beta-blockers on morbidity and mortality in a population-based cohort of 11,942 elderly patients with heart failure." The American journal of medicine 113 (8) doi:
Sin Don D, Mayers Irvin, Man Godfrey C W, Ghahary Ali, Pawluk Lawrence 2002. "Can continuous positive airway pressure therapy improve the general health status of patients with obstructive sleep apnea?: a clinical effectiveness study." Chest 122 (5) doi:
Sin Don D, Man S F Paul 2002. "Low-dose inhaled corticosteroid therapy and risk of emergency department visits for asthma." Archives of internal medicine 162 (14) doi:
Sin Don D, Jones Richard L, Man S F Paul 2002. "Obesity is a risk factor for dyspnea but not for airflow obstruction." Archives of internal medicine 162 (13) doi:
Alsaeedi Abdullah, Sin Don D, McAlister Finlay A 2002. "The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review of randomized placebo-controlled trials." The American journal of medicine 113 (1) doi:
Sin Don D, Wells Heather, Svenson Lawrence W, Man S F Paul 2002. "Asthma and COPD among aboriginals in Alberta, Canada." Chest 121 (6) doi:
Sin Don D, Stafinski Tania, Ng Ying Chu, Bell Neil R, Jacobs Philip 2002. "The impact of chronic obstructive pulmonary disease on work loss in the United States." American journal of respiratory and critical care medicine 165 (5) doi:10.1164/ajrccm.165.5.2104055
Sin Don D, Mayers Irvin, Man Godfrey C W, Pawluk Larry 2002. "Long-term compliance rates to continuous positive airway pressure in obstructive sleep apnea: a population-based study." Chest 121 (2) doi:
Sin Don D, Bell Neil R, Svenson Lawrence W, Man S F Paul 2002. "The impact of follow-up physician visits on emergency readmissions for patients with asthma and chronic obstructive pulmonary disease: a population-based study." The American journal of medicine 112 (2) doi: