Saikku Pekka

Top coauthors of Saikku Pekka

Leinonen Maija (44 papers)

Silvennoinen-Kassinen Sylvi (14 papers)

Bloigu Aini (14 papers)

Paldanius Mika (12 papers)

Törmäkangas Liisa (7 papers)

List of Saikku Pekka publications


Lumme Sonja, Tenkanen Leena, Langseth Hilde, Gislefoss Randi, Hakama Matti, et al. 2016. "Longitudinal biobanks-based study on the joint effects of infections, nutrition and hormones on risk of prostate cancer." Acta oncologica (Stockholm, Sweden) doi:10.3109/0284186X.2016.1139178


Kauppila Jaana, Rönkkö Esa, Juvonen Raija, Saukkoriipi Annika, Saikku Pekka, et al. 2014. "Influenza C virus infection in military recruits--symptoms and clinical manifestation." Journal of medical virology 86 (5) doi:10.1002/jmv.23756


Hyvärinen Kati, Tuomainen Anita M, Laitinen Saara, Alfthan Georg, Salminen Irma, et al. 2013. "The effect of proatherogenic pathogens on adipose tissue transcriptome and fatty acid distribution in apolipoprotein E-deficient mice." BMC genomics 14 doi:10.1186/1471-2164-14-709


Salin Olli, Törmäkangas Liisa, Leinonen Maija, Saario Elise, Hagström Marja, et al. 2011. "Corn mint (Mentha arvensis) extract diminishes acute Chlamydia pneumoniae infection in vitro and in vivo." Journal of agricultural and food chemistry 59 (24) doi:10.1021/jf2032473
Salin Olli P, Pohjala Leena L, Saikku Pekka, Vuorela Heikki J, Leinonen Maija, Vuorela Pia M 2011. "Effects of coadministration of natural polyphenols with doxycycline or calcium modulators on acute Chlamydia pneumoniae infection in vitro." The Journal of antibiotics 64 (11) doi:10.1038/ja.2011.79
Tuomainen Anita M, Hyvärinen Kati, Ehlers Pauliina I, Mervaala Eero, Leinonen Maija, et al. 2011. "The effect of proatherogenic microbes on macrophage cholesterol homeostasis in apoE-deficient mice." Microbial pathogenesis 51 (3) doi:10.1016/j.micpath.2011.03.003
Gazvani Rafet, Coyne Lucy, Anttila Tarja, Saikku Pekka, Paavonen Jorma, Templeton Alan 2011. "Antibodies to Chlamydia trachomatis in serum and peritoneal fluid of women with endometriosis." Human fertility (Cambridge, England) 14 (1) doi:10.3109/14647273.2010.548846
Rantala Aino, Lajunen Taina, Juvonen Raija, Bloigu Aini, Paldanius Mika, et al. 2011. "Low mannose-binding lectin levels and MBL2 gene polymorphisms associate with Chlamydia pneumoniae antibodies." Innate immunity 17 (1) doi:10.1177/1753425909349759
Rantala Aino, Lajunen Taina, Juvonen Raija, Silvennoinen-Kassinen Sylvi, Peitso Ari, et al. 2011. "Association of IL-6 and IL-6R gene polymorphisms with susceptibility to respiratory tract infections in young Finnish men." Human immunology 72 (1) doi:10.1016/j.humimm.2010.10.010


Morin-Papunen Laure C, Duleba Antoni J, Bloigu Aini, Järvelin Marjo-Riitta, Saikku Pekka, Pouta Anneli 2010. "Chlamydia antibodies and self-reported symptoms of oligo-amenorrhea and hirsutism: a new etiologic factor in polycystic ovary syndrome?" Fertility and sterility 94 (5) doi:10.1016/j.fertnstert.2009.10.021
Yan Ying, Silvennoinen-Kassinen Sylvi, Leinonen Maija, Saikku Pekka 2010. "Rapamycin can inhibit the development of Chlamydia pneumoniae, which might partly contribute to the prevention of in-stent restenosis." Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 24 (3) doi:10.1007/s10557-010-6238-8
Vikatmaa Pirkka, Lajunen Taina, Ikonen Tuija S, Pussinen Pirkko J, Lepäntalo Mauri, et al. 2010. "Chlamydial lipopolysaccharide (cLPS) is present in atherosclerotic and aneurysmal arterial wall--cLPS levels depend on disease manifestation." Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 19 (1) doi:10.1016/j.carpath.2008.10.012
Poikonen Kari, Lajunen Taina, Silvennoinen-Kassinen Sylvi, Leinonen Maija, Saikku Pekka 2010. "Quantification of Chlamydia pneumoniae in cultured human macrophages and HL cells: comparison of real-time PCR, immunofluorescence and ELISA methods." APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 118 (1) doi:10.1111/j.1600-0463.2009.02557.x


Paakkanen Riitta, Palikhe Anil, Seppänen Mikko, Nieminen Markku S, Vauhkonen Hanna, et al. 2009. "Beneficial effect of clarithromycin in patients with acute coronary syndrome and complement C4 deficiencies." Scandinavian cardiovascular journal : SCJ 43 (6) doi:10.1080/14017430902874305
Hyvärinen Kati, Tuomainen Anita M, Laitinen Saara, Bykov Igor L, Törmäkangas Liisa, et al. 2009. "Chlamydial and periodontal pathogens induce hepatic inflammation and fatty acid imbalance in apolipoprotein E-deficient mice." Infection and immunity 77 (8) doi:10.1128/IAI.00389-09
Canoy Dexter, Pouta Anneli, Ruokonen Aimo, Hartikainen Anna-Liisa, Saikku Pekka, Järvelin Marjo-Riitta 2009. "Weight at birth and infancy in relation to adult leukocyte count: a population-based study of 5619 men and women followed from the fetal period to adulthood." The Journal of clinical endocrinology and metabolism 94 (6) doi:10.1210/jc.2008-2545
Palikhe Anil, Tiirola Terttu, Puolakkainen Mirja, Nieminen Markku S, Saikku Pekka, et al. 2009. "Chlamydia pneumoniae DNA is present in peripheral blood mononuclear cells during acute coronary syndrome and correlates with chlamydial lipopolysaccharide levels in serum." Scandinavian journal of infectious diseases 41 (3) doi:10.1080/00365540902737968
Pesonen Erkki, Tiirola Terttu, Andsberg Eeva, Jauhiainen Matti, Paldanius Matti, et al. 2009. "Serum chlamydial lipopolysaccharide as a prognostic factor for a new cardiovascular event." Heart & lung : the journal of critical care 38 (3) doi:10.1016/j.hrtlng.2008.06.001


Lajunen Taina, Vikatmaa Pirkka, Bloigu Aini, Ikonen Tuija, Lepäntalo Mauri, et al. 2008. "Chlamydial LPS and high-sensitivity CRP levels in serum are associated with an elevated body mass index in patients with cardiovascular disease." Innate immunity 14 (6) doi:10.1177/1753425908099172
Rantala Aino, Lajunen Taina, Juvonen Raija, Bloigu Aini, Silvennoinen-Kassinen Sylvi, et al. 2008. "Mannose-binding lectin concentrations, MBL2 polymorphisms, and susceptibility to respiratory tract infections in young men." The Journal of infectious diseases 198 (8) doi:10.1086/591912
Yan Ying, Silvennoinen-Kassinen Sylvi, Törmäkangas Liisa, Leinonen Maija, Saikku Pekka 2008. "Selective cyclooxygenase inhibitors prevent the growth of Chlamydia pneumoniae in HL cells." International journal of antimicrobial agents 32 (1) doi:10.1016/j.ijantimicag.2008.02.021
Juvonen Raija, Bloigu Aini, Peitso Ari, Silvennoinen-Kassinen Sylvi, Saikku Pekka, et al. 2008. "Risk factors for acute respiratory tract illness in military conscripts." Respirology (Carlton, Vic.) 13 (4) doi:10.1111/j.1440-1843.2008.01299.x
Lajunen Taina, Vikatmaa Pirkka, Ikonen Tuija, Lepäntalo Mauri, Lounatmaa Kari, et al. 2008. "Comparison of polymerase chain reaction methods, in situ hybridization, and enzyme immunoassay for detection of Chlamydia pneumoniae in atherosclerotic carotid plaques." Diagnostic microbiology and infectious disease 61 (2) doi:10.1016/j.diagmicrobio.2008.01.006
Erkkilä Leena, Saario Elise, Laitinen Kirsi, Saikku Pekka, Leinonen Maija 2008. "Intragastric primary infection sensitizes to lung reinfection in a Chlamydia pneumoniae mouse model." Vaccine 26 (20) doi:10.1016/j.vaccine.2008.03.034
Tzoulaki Ioanna, Jarvelin Marjo-Riitta, Hartikainen Anna-Liisa, Leinonen Maija, Pouta Anneli, et al. 2008. "Size at birth, weight gain over the life course, and low-grade inflammation in young adulthood: northern Finland 1966 Birth Cohort study." European heart journal 29 (8) doi:10.1093/eurheartj/ehn105
Juvonen Raija, Bloigu Aini, Peitso Ari, Silvennoinen-Kassinen Sylvi, Saikku Pekka, et al. 2008. "Training improves physical fitness and decreases CRP also in asthmatic conscripts." The Journal of asthma : official journal of the Association for the Care of Asthma 45 (3) doi:10.1080/02770900701883790
Palikhe Anil, Lokki Marja-Liisa, Saikku Pekka, Leinonen Maija, Paldanius Mika, et al. 2008. "Association of Chlamydia pneumoniae infection with HLA-B*35 in patients with coronary artery disease." Clinical and vaccine immunology : CVI 15 (1) doi:10.1128/CVI.00163-07
Karinen Liisa, Leinonen Maija, Bloigu Aini, Paldanius Mika, Koskela Pentti, et al. 2008. "Maternal serum Chlamydia pneumoniae antibodies and CRP levels in women with preeclampsia and gestational hypertension." Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy 27 (2) doi:10.1080/10641950701885188


Paldanius Mika, Juvonen Raija, Leinonen Maija, Bloigu Aini, Silvennoinen-Kassinen Sylvi, Saikku Pekka 2007. "Asthmatic persons are prone to the persistence of Chlamydia pneumoniae antibodies." Diagnostic microbiology and infectious disease 59 (2) doi:10.1016/j.diagmicrobio.2007.04.004
Tiirola Terttu, Sinisalo Juha, Nieminen Markku S, Silvennoinen-Kassinen Sylvi, Paldanius Mika, et al. 2007. "Chlamydial lipopolysaccharide is present in serum during acute coronary syndrome and correlates with CRP levels." Atherosclerosis 194 (2) doi:10.1016/j.atherosclerosis.2006.08.013
Madeleine Margaret M, Anttila Tarja, Schwartz Stephen M, Saikku Pekka, Leinonen Maija, et al. 2007. "Risk of cervical cancer associated with Chlamydia trachomatis antibodies by histology, HPV type and HPV cofactors." International journal of cancer. Journal international du cancer 120 (3) doi:10.1002/ijc.22325


Korhonen Taina, Grauling-Halama Silke, Halama Niels, Silvennoinen-Kassinen Sylvi, Leinonen Maija, Saikku Pekka 2006. "Rapid genotyping of lipopolysaccharide-binding protein (LBP) C(1341)-->T (Leu(436)-->Phe) polymorphism by LightCycler real-time PCR." Journal of immunological methods 317 (1-2) doi:10.1016/j.jim.2006.07.029
Paldanius Mika, Leinonen Maija, Virkkunen Hanna, Tenkanen Leena, Sävykoski Tiina, et al. 2006. "Chlamydia pneumoniae antibody levels before coronary events in the Helsinki Heart Study as measured by different methods." Diagnostic microbiology and infectious disease 56 (3) doi:10.1016/j.diagmicrobio.2006.04.007
Törmäkangas Liisa, Ketonen Juha, Leinonen Maija, Saikku Pekka, Paakkari Ilari 2006. "Increased prostanoid dependency of arterial relaxation in Chlamydia pneumoniae-infected mice." Journal of medical microbiology 55 (Pt 8) doi:10.1099/jmm.0.46516-0
Yan Ying, Silvennoinen-Kassinen Sylvi, Leinonen Maija, Saikku Pekka 2006. "Inhibitory effect of heparan sulfate-like glycosaminoglycans on the infectivity of Chlamydia pneumoniae in HL cells varies between strains." Microbes and infection / Institut Pasteur 8 (3) doi:10.1016/j.micinf.2005.10.010
Tiirola Terttu, Jaakkola Anne, Bloigu Aini, Paldanius Mika, Sinisalo Juha, et al. 2006. "Novel enzyme immunoassay utilizing lipopolysaccharide-binding protein as a capture molecule for the measurement of chlamydial lipopolysaccharide in serum." Diagnostic microbiology and infectious disease 54 (1) doi:10.1016/j.diagmicrobio.2005.09.001


Törmäkangas Liisa, Vuorela Pia, Saario Elise, Leinonen Maija, Saikku Pekka, Vuorela Heikki 2005. "In vivo treatment of acute Chlamydia pneumoniae infection with the flavonoids quercetin and luteolin and an alkyl gallate, octyl gallate, in a mouse model." Biochemical pharmacology 70 (8) doi:10.1016/j.bcp.2005.07.012
Törmäkangas Liisa, Erkkilä Leena, Korhonen Taina, Tiirola Terttu, Bloigu Aini, et al. 2005. "Effects of repeated Chlamydia pneumoniae inoculations on aortic lipid accumulation and inflammatory response in C57BL/6J mice." Infection and immunity 73 (10) doi:10.1128/IAI.73.10.6458-6466.2005
Erkkilä Leena, Jauhiainen Matti, Laitinen Kirsi, Haasio Kristiina, Tiirola Terttu, et al. 2005. "Effect of simvastatin, an established lipid-lowering drug, on pulmonary Chlamydia pneumoniae infection in mice." Antimicrobial agents and chemotherapy 49 (9) doi:10.1128/AAC.49.9.3959-3962.2005
Karinen Liisa, Pouta Anneli, Bloigu Aini, Koskela Pentti, Paldanius Mika, et al. 2005. "Serum C-reactive protein and Chlamydia trachomatis antibodies in preterm delivery." Obstetrics and gynecology 106 (1) doi:10.1097/01.AOG.0000164464.11979.5d
Paldanius Mika, Bloigu Aini, Alho Marianne, Leinonen Maija, Saikku Pekka 2005. "Prevalence and persistence of Chlamydia pneumoniae antibodies in healthy laboratory personnel in Finland." Clinical and diagnostic laboratory immunology 12 (5) doi:10.1128/CDLI.12.5.654-659.2005
Yan Ying, Silvennoinen-Kassinen Sylvi, Leinonen Maija, Saikku Pekka 2005. "Methodological aspects affecting the infectivity of Chlamydia pneumoniae in cell cultures in vitro." Journal of microbiological methods 61 (1) doi:10.1016/j.mimet.2004.11.003
Anttila Tarja, Tenkanen Leena, Lumme Sonja, Leinonen Maija, Gislefoss Randi Elin, et al. 2005. "Chlamydial antibodies and risk of prostate cancer." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 14 (2) doi:10.1158/1055-9965.EPI-03-0325


Törmäkangas Liisa, Alakärppä Hannu, David Denise Bem, Leinonen Maija, Saikku Pekka 2004. "Telithromycin treatment of chronic Chlamydia pneumoniae infection in C57BL/6J mice." Antimicrobial agents and chemotherapy 48 (10) doi:10.1128/AAC.48.10.3655-3661.2004


Lehtimäki Terho, Laaksonen Reijo, Janatuinen Tuula, Vesalainen Risto, Nuutila Pirjo, et al. 2003. "Interleukin-1B genotype modulates the improvement of coronary artery reactivity by lipid-lowering therapy with pravastatin: a placebo-controlled positron emission tomography study in young healthy men." Pharmacogenetics 13 (10) doi:10.1097/01.fpc.0000054130.14659.39
Jartti Laura, Raitakari Olli T, Järvisalo Mikko J, Hammar Niklas, Kaprio Jaakko, et al. 2003. "Higher prevalence of Chlamydia pneumoniae seropositivity in Finnish twins compared with co-twins living in Sweden: relationships with markers of subclinical atherosclerosis." Clinical science (London, England : 1979) 105 (3) doi:10.1042/CS20030001
Karppinen Jaro, Mikkonen Paula, Kurunlahti Mauno, Tervonen Osmo, Paldanius Mika, et al. 2003. "Chronic Chlamydia pneumoniae infection increases the risk of occlusion of lumbar segmental arteries of patients with sciatica: a 3-year follow-up study." Spine 28 (15) doi:10.1097/01.BRS.0000083229.42276.A0
Kervinen Helena, Huittinen Tiina, Vaarala Outi, Leinonen Maija, Saikku Pekka, et al. 2003. "Antibodies to human heat shock protein 60, hypertension and dyslipidemia. A study of joint effects on coronary risk." Atherosclerosis 169 (2) doi:
Huittinen Tiina, Leinonen Maija, Tenkanen Leena, Virkkunen Hanna, Mänttäri Matti, et al. 2003. "Synergistic effect of persistent Chlamydia pneumoniae infection, autoimmunity, and inflammation on coronary risk." Circulation 107 (20) doi:10.1161/01.CIR.0000068338.17948.22
Paldanius Mika, Bloigu Aini, Leinonen Maija, Saikku Pekka 2003. "Measurement of Chlamydia pneumoniae-specific immunoglobulin A (IgA) antibodies by the microimmunofluorescence (MIF) method: comparison of seven fluorescein-labeled anti-human IgA conjugates in an in-house MIF test using one commercial MIF and one enzyme immunoassay kit." Clinical and diagnostic laboratory immunology 10 (1) doi:


Erkkilä Leena, Laitinen Kirsi, Laurila Aino, Saikku Pekka, Leinonen Maija 2002. "Experimental Chlamydia pneumoniae infection in NIH/S mice: effect of reinoculation with chlamydial or cell preparation on culture, PCR and histological findings of lung tissue." Vaccine 20 (17-18) doi:
Lehto Seppo, Niskanen Leo, Suhonen Matti, Rönnemaa Tapani, Saikku Pekka, Laakso Markku 2002. "Association between Chlamydia pneumoniae antibodies and intimal calcification in femoral arteries of nondiabetic patients." Archives of internal medicine 162 (5) doi:
Huittinen Tiina, Leinonen Maija, Tenkanen Leena, Mänttäri Matti, Virkkunen Hanna, et al. 2002. "Autoimmunity to human heat shock protein 60, Chlamydia pneumoniae infection, and inflammation in predicting coronary risk." Arteriosclerosis, thrombosis, and vascular biology 22 (3) doi:
Leinonen Maija, Saikku Pekka 2002. "Evidence for infectious agents in cardiovascular disease and atherosclerosis." The Lancet infectious diseases 2 (1) doi:


Saikku Pekka 1998. "Diagnosis of Chlamydia pneumoniae." Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 4 Suppl 4 doi:


Saikku Pekka 1997. "Atypical respiratory pathogens." Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 3 (6) doi:


Saikku Pekka 1996. "Chlamydia pneumoniae and cardiovascular diseases." Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 1 Suppl 1 doi: