Rennard Stephen I

Top coauthors of Rennard Stephen I

Liu Xiangde (65 papers)

Kobayashi Tetsu (35 papers)

Silverman Edwin K (31 papers)

Tal-Singer Ruth (28 papers)

Wang Xingqi (28 papers)

List of Rennard Stephen I publications

2018

Bhatt Surya P, Kim Young-Il, Harrington Kathy F, Hokanson John E, Lutz Sharon M, et al. 2018. "Smoking duration alone provides stronger risk estimates of chronic obstructive pulmonary disease than pack-years." Thorax doi:10.1136/thoraxjnl-2017-210722
Bafadhel Mona, Peterson Stefan, De Blas Miguel A, Calverley Peter M, Rennard Stephen I, et al. 2018. "Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials." The Lancet. Respiratory medicine doi:10.1016/S2213-2600(18)30006-7

2017

McDonald Merry-Lynn N, Diaz Alejandro A, Rutten Erica, Lutz Sharon M, Harmouche Rola, et al. 2017. "Chest computed tomography-derived low fat-free mass index and mortality in COPD." The European respiratory journal 50 (6) doi:10.1183/13993003.01134-2017
Abdulai Raolat M, Jellesmark Jensen Tina, Patel Naimish R, Polkey Michael I, Jansson Paul, et al. 2017. "Deterioration of Limb Muscle Function During Acute Exacerbation of Chronic Obstructive Pulmonary Disease." American journal of respiratory and critical care medicine doi:10.1164/rccm.201703-0615CI
Thakare Rhishikesh, Chhonker Yashpal S, Gautam Nagsen, Nelson Amy, Casaburi Richard, et al. 2017. "Simultaneous LC-MS/MS analysis of eicosanoids and related metabolites in human serum, sputum and BALF." Biomedical chromatography : BMC doi:10.1002/bmc.4102
Quezada Wilson A, Whippo Beth A, Jellen Patricia A, Leidy Nancy K, Mannino David M, et al. 2017. "How Well Does CAPTURE Translate?: An Exploratory Analysis of a COPD Case-Finding Method for Spanish-Speaking Patients." Chest 152 (4) doi:10.1016/j.chest.2017.03.047
McCamley John D, Pisciotta Eric J, Yentes Jennifer M, Wurdeman Shane R, Rennard Stephen I, et al. 2017. "Gait deficiencies associated with peripheral artery disease are different than chronic obstructive pulmonary disease." Gait & posture 57 doi:10.1016/j.gaitpost.2017.06.018
Busch Robert, Hobbs Brian D, Zhou Jin, Castaldi Peter J, McGeachie Michael J, et al. 2017. "Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects." American journal of respiratory cell and molecular biology 57 (1) doi:10.1165/rcmb.2016-0331OC
Yentes Jennifer M, Rennard Stephen I, Schmid Kendra K, Blanke Daniel, Stergiou Nicholas 2017. "Patients with Chronic Obstructive Pulmonary Disease Walk with Altered Step Time and Step Width Variability as Compared with Healthy Control Subjects." Annals of the American Thoracic Society 14 (6) doi:10.1513/AnnalsATS.201607-547OC
McDonald Merry-Lynn Noelle, Won Sungho, Mattheisen Manuel, Castaldi Peter J, Cho Michael H, et al. 2017. "Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1." Journal of cachexia, sarcopenia and muscle 8 (3) doi:10.1002/jcsm.12171
Martinez Carlos H, Murray Susan, Barr R Graham, Bleecker Eugene, Bowler Russell P, et al. 2017. "Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort." Annals of the American Thoracic Society 14 (5) doi:10.1513/AnnalsATS.201610-815OC
Jones Paul W, Gelhorn Heather, Wilson Hilary, Benson Victoria S, Karlsson Niklas, et al. 2017. "Socioeconomic Status as a Determinant of Health Status Treatment Response in COPD Trials." Chronic obstructive pulmonary diseases (Miami, Fla.) 4 (2) doi:10.15326/jcopdf.4.2.2017.0132
Müllerova Hana, Gelhorn Heather, Wilson Hilary, Benson Victoria S, Karlsson Niklas, et al. 2017. "St George's Respiratory Questionnaire Score Predicts Outcomes in Patients with COPD: Analysis of Individual Patient Data in the COPD Biomarkers Qualification Consortium Database." Chronic obstructive pulmonary diseases (Miami, Fla.) 4 (2) doi:10.15326/jcopdf.4.2.2017.0131
Jones Paul W, Gelhorn Heather, Karlsson Niklas, Menjoge Shailendra, Müllerova Hana, et al. 2017. "Baseline Severity as Predictor of Change in St George's Respiratory Questionnaire Scores in Trials of Long-acting Bronchodilators with COPD Patients." Chronic obstructive pulmonary diseases (Miami, Fla.) 4 (2) doi:10.15326/jcopdf.4.2.2017.0129
Tabberer Maggie, Benson Victoria S, Gelhorn Heather, Wilson Hilary, Karlsson Niklas, et al. 2017. "The COPD Biomarkers Qualification Consortium Database: Baseline Characteristics of the St George's Respiratory Questionnaire Dataset." Chronic obstructive pulmonary diseases (Miami, Fla.) 4 (2) doi:10.15326/jcopdf.4.2.2017.0128
Jones Paul W, Gelhorn Heather, Wilson Hilary, Karlsson Niklas, Menjoge Shailendra, et al. 2017. "Responder Analyses for Treatment Effects in COPD Using the St George's Respiratory Questionnaire." Chronic obstructive pulmonary diseases (Miami, Fla.) 4 (2) doi:10.15326/jcopdf.4.2.2017.0130
Hobbs Brian D, de Jong Kim, Lamontagne Maxime, Bossé Yohan, Shrine Nick, et al. 2017. "Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis." Nature genetics 49 (3) doi:10.1038/ng.3752
Ikari Jun, Nelson Amy J, Obaid Jannah, Giron-Martinez Alvaro, Ikari Kumiko, et al. 2017. "Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease." PloS one 12 (9) doi:10.1371/journal.pone.0184039
Anderson Wayne H, Ha Jae Wook, Couper David J, O'Neal Wanda K, Barr R Graham, et al. 2017. "Variability in objective and subjective measures affects baseline values in studies of patients with COPD." PloS one 12 (9) doi:10.1371/journal.pone.0184606

2016

Andrianopoulos Vasileios, Celli Bartolome R, Franssen Frits M E, Pinto-Plata Victor M, Calverley Peter M A, et al. 2016. "Determinants of exercise-induced oxygen desaturation including pulmonary emphysema in COPD: Results from the ECLIPSE study." Respiratory medicine 119 doi:10.1016/j.rmed.2016.08.023
Martinez Fernando J, Rabe Klaus F, Sethi Sanjay, Pizzichini Emilio, McIvor Andrew, et al. 2016. "Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting β2-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE(2)SPOND). A Randomized Clinical Trial." American journal of respiratory and critical care medicine 194 (5) doi:10.1164/rccm.201607-1349OC
Keene Jason D, Jacobson Sean, Kechris Katerina, Kinney Gregory L, Foreman Marilyn G, et al. 2016. "Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts." American journal of respiratory and critical care medicine doi:10.1164/rccm.201607-1330OC
Sun Wei, Kechris Katerina, Jacobson Sean, Drummond M Bradley, Hawkins Gregory A, et al. 2016. "Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD." PLoS genetics 12 (8) doi:10.1371/journal.pgen.1006011
Kim Victor, Zhao Huaqing, Boriek Aladin M, Anzueto Antonio, Soler Xavier, et al. 2016. "Persistent and Newly Developed Chronic Bronchitis Are Associated with Worse Outcomes in Chronic Obstructive Pulmonary Disease." Annals of the American Thoracic Society doi:10.1513/AnnalsATS.201512-800OC
Joppa Pavol, Tkacova Ruzena, Franssen Frits M E, Hanson Corrine, Rennard Stephen I, et al. 2016. "Sarcopenic Obesity, Functional Outcomes, and Systemic Inflammation in Patients With Chronic Obstructive Pulmonary Disease." Journal of the American Medical Directors Association doi:10.1016/j.jamda.2016.03.020
Martinez Carlos H, Diaz Alejandro A, Parulekar Amit D, Rennard Stephen I, Kanner Richard E, et al. 2016. "Age-Related Differences in Health-Related Quality of Life in COPD: An Analysis of the COPDGene and SPIROMICS Cohorts." Chest 149 (4) doi:10.1016/j.chest.2015.11.025
Rabinovich Roberto A, Miller Bruce E, Wrobel Karolina, Ranjit Kareshma, Williams Michelle C, et al. 2016. "Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD." The European respiratory journal doi:10.1183/13993003.01824-2015
Miller Bruce E, Tal-Singer Ruth, Rennard Stephen I, Furtwaengler Armin, Leidy Nancy, et al. 2016. "Plasma Fibrinogen Qualification as a Drug Development Tool in Chronic Obstructive Pulmonary Disease. Perspective of the Chronic Obstructive Pulmonary Disease Biomarker Qualification Consortium." American journal of respiratory and critical care medicine 193 (6) doi:10.1164/rccm.201509-1722PP
Putcha Nirupama, Barr R Graham, Han Meilan K, Woodruff Prescott G, Bleecker Eugene R, et al. 2016. "Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort." Thorax doi:10.1136/thoraxjnl-2015-207487
Leidy Nancy K, Malley Karen G, Steenrod Anna W, Mannino David M, Make Barry J, et al. 2016. "Insight into Best Variables for COPD Case Identification: A Random Forests Analysis." Chronic obstructive pulmonary diseases (Miami, Fla.) 3 (1) doi:10.15326/jcopdf.3.1.2015.0144
Calverley Peter M A, Rennard Stephen I, Clerisme-Beaty Emmanuelle, Metzdorf Norbert, Zubek Valentina Bayer, ZuWallack Richard 2016. "Effect of tiotropium on night-time awakening and daily rescue medication use in patients with COPD." Respiratory research 17 (1) doi:10.1186/s12931-016-0340-9
Leung Janice M, Chen Virginia, Hollander Zsuzsanna, Dai Darlene, Tebbutt Scott J, et al. 2016. "COPD Exacerbation Biomarkers Validated Using Multiple Reaction Monitoring Mass Spectrometry." PloS one 11 (8) doi:10.1371/journal.pone.0161129
Rennard Stephen I, Martinez Fernando J, Rabe Klaus F, Sethi Sanjay, Pizzichini Emilio, et al. 2016. "Effects of roflumilast in COPD patients receiving inhaled corticosteroid/long-acting β2-agonist fixed-dose combination: RE(2)SPOND rationale and study design." International journal of chronic obstructive pulmonary disease 11 doi:10.2147/COPD.S109661

2015

Sato Tadashi, Baskoro Hario, Rennard Stephen I, Seyama Kuniaki, Takahashi Kazuhisa 2015. "MicroRNAs as Therapeutic Targets in Lung Disease: Prospects and Challenges." Chronic obstructive pulmonary diseases (Miami, Fla.) 3 (1) doi:10.15326/jcopdf.3.1.2015.0160
Andrianopoulos Vasileios, Wouters Emiel F M, Pinto-Plata Victor M, Vanfleteren Lowie E G W, Bakke Per S, et al. 2015. "Prognostic value of variables derived from the six-minute walk test in patients with COPD: Results from the ECLIPSE study." Respiratory medicine 109 (9) doi:10.1016/j.rmed.2015.06.013
Rennard Stephen I 2015. "The Promise of Observational Studies (ECLIPSE, SPIROMICS, and COPDGene) in Achieving the Goal of Personalized Treatment of Chronic Obstructive Pulmonary Disease." Seminars in respiratory and critical care medicine 36 (4) doi:10.1055/s-0035-1555609
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar A, et al. 2015. "An official American Thoracic Society/European Respiratory Society statement: research questions in COPD." European respiratory review : an official journal of the European Respiratory Society 24 (136) doi:10.1183/16000617.00000315
Rennard Stephen I, Drummond M Bradley 2015. "Early chronic obstructive pulmonary disease: definition, assessment, and prevention." Lancet (London, England) 385 (9979) doi:10.1016/S0140-6736(15)60647-X
Wilke Sarah, Jones Paul W, Müllerova H, Vestbo Jørgen, Tal-Singer Ruth, et al. 2015. "One-year change in health status and subsequent outcomes in COPD." Thorax 70 (5) doi:10.1136/thoraxjnl-2014-205697
Rennard Stephen I, Dale David C, Donohue James F, Kanniess Frank, Magnussen Helgo, et al. 2015. "CXCR2 Antagonist MK-7123. A Phase 2 Proof-of-Concept Trial for Chronic Obstructive Pulmonary Disease." American journal of respiratory and critical care medicine 191 (9) doi:10.1164/rccm.201405-0992OC
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar, et al. 2015. "An official American Thoracic Society/European Respiratory Society statement: research questions in COPD." The European respiratory journal 45 (4) doi:10.1183/09031936.00009015
Ikari Jun, Smith Lynette M, Nelson Amy J, Iwasawa Shunichiro, Gunji Yoko, et al. 2015. "Effect of culture conditions on microRNA expression in primary adult control and COPD lung fibroblasts in vitro." In vitro cellular & developmental biology. Animal 51 (4) doi:10.1007/s11626-014-9820-8
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar, et al. 2015. "An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 191 (7) doi:10.1164/rccm.201501-0044ST
Rennard Stephen I, Locantore Nicholas, Delafont Bruno, Tal-Singer Ruth, Silverman Edwin K, et al. 2015. "Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis." Annals of the American Thoracic Society 12 (3) doi:10.1513/AnnalsATS.201403-125OC
Ebbert Jon O, Hughes John R, West Robert J, Rennard Stephen I, Russ Cristina, et al. 2015. "Effect of varenicline on smoking cessation through smoking reduction: a randomized clinical trial." JAMA 313 (7) doi:10.1001/jama.2015.280
Mannino David M, Tal-Singer Ruth, Lomas David A, Vestbo Jorgen, Graham Barr R, et al. 2015. "Plasma Fibrinogen as a Biomarker for Mortality and Hospitalized Exacerbations in People with COPD." Chronic obstructive pulmonary diseases (Miami, Fla.) 2 (1) doi:10.15326/jcopdf.2.1.2014.0138
Yentes Jennifer M, Schmid Kendra K, Blanke Daniel, Romberger Debra J, Rennard Stephen I, Stergiou Nicholas 2015. "Gait mechanics in patients with chronic obstructive pulmonary disease." Respiratory research 16 doi:10.1186/s12931-015-0187-5
Li Ying-Ji, Kanaji Nobuhiro, Wang Xing-Qi, Sato Tadashi, Nakanishi Masanori, et al. 2015. "Prostaglandin E2 switches from a stimulator to an inhibitor of cell migration after epithelial-to-mesenchymal transition." Prostaglandins & other lipid mediators 116-117 doi:10.1016/j.prostaglandins.2014.10.003
Freeman Christine M, Crudgington Sean, Stolberg Valerie R, Brown Jeanette P, Sonstein Joanne, et al. 2015. "Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)." Journal of translational medicine 13 doi:10.1186/s12967-014-0374-z
Morrow Jarrett D, Qiu Weiliang, Chhabra Divya, Rennard Stephen I, Belloni Paula, et al. 2015. "Identifying a gene expression signature of frequent COPD exacerbations in peripheral blood using network methods." BMC medical genomics 8 doi:10.1186/s12920-014-0072-y
Han MeiLan K, Steenrod Anna W, Bacci Elizabeth D, Leidy Nancy K, Mannino David M, et al. 2015. "Identifying Patients with Undiagnosed COPD in Primary Care Settings: Insight from Screening Tools and Epidemiologic Studies." Chronic obstructive pulmonary diseases (Miami, Fla.) 2 (2) doi:10.15326/jcopdf.2.2.2014.0152
Leidy Nancy K, Kim Katherine, Bacci Elizabeth D, Yawn Barbara P, Mannino David M, et al. 2015. "Identifying cases of undiagnosed, clinically significant COPD in primary care: qualitative insight from patients in the target population." NPJ primary care respiratory medicine 25 doi:10.1038/npjpcrm.2015.24

2014

Janssen Daisy J A, Müllerova Hana, Agusti Alvar, Yates Julie C, Tal-Singer Ruth, et al. 2014. "Persistent systemic inflammation and symptoms of depression among patients with COPD in the ECLIPSE cohort." Respiratory medicine 108 (11) doi:10.1016/j.rmed.2014.07.013
McDonald Merry-Lynn N, Cho Michael H, Sørheim Inga-Cecilie, Lutz Sharon M, Castaldi Peter J, et al. 2014. "Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 51 (5) doi:10.1165/rcmb.2014-0135OC
Bhatt Surya P, Wells James M, Kim Victor, Criner Gerard J, Hersh Craig P, et al. 2014. "Radiological correlates and clinical implications of the paradoxical lung function response to β₂ agonists: an observational study." The Lancet. Respiratory medicine 2 (11) doi:10.1016/S2213-2600(14)70185-7
Kanaji Nobuhiro, Basma Hesham, Nelson Amy, Farid Maha, Sato Tadashi, et al. 2014. "Fibroblasts that resist cigarette smoke-induced senescence acquire profibrotic phenotypes." American journal of physiology. Lung cellular and molecular physiology 307 (5) doi:10.1152/ajplung.00041.2014
Wells J Michael, O'Reilly Philip J, Szul Tomasz, Sullivan Daniel I, Handley Guy, et al. 2014. "An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 190 (1) doi:10.1164/rccm.201401-0145OC
Faner Rosa, Tal-Singer Ruth, Riley John H, Celli Bartolomé, Vestbo Jørgen, et al. 2014. "Lessons from ECLIPSE: a review of COPD biomarkers." Thorax 69 (7) doi:10.1136/thoraxjnl-2013-204778
Kobayashi Tetsu, Kim HuiJung, Liu Xiangde, Sugiura Hisatoshi, Kohyama Tadashi, et al. 2014. "Matrix metalloproteinase-9 activates TGF-β and stimulates fibroblast contraction of collagen gels." American journal of physiology. Lung cellular and molecular physiology 306 (11) doi:10.1152/ajplung.00015.2014
Yentes Jennifer M, Blanke Daniel, Rennard Stephen I, Stergiou Nicholas 2014. "The Effect of a Short Duration, High Intensity Exercise Intervention on Gait Biomechanics in Patients With COPD: Findings From a Pilot Study." Chronic obstructive pulmonary diseases (Miami, Fla.) 1 (1) doi:10.15326/jcopdf.1.1.2013.0002
Vestbo Jørgen, Agusti Alvar, Wouters Emiel F M, Bakke Per, Calverley Peter M A, et al. 2014. "Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team." American journal of respiratory and critical care medicine 189 (9) doi:10.1164/rccm.201311-2006PP
Drummond M Bradley, Buist A Sonia, Crapo James D, Wise Robert A, Rennard Stephen I 2014. "Chronic obstructive pulmonary disease: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases." Annals of the American Thoracic Society 11 Suppl 3 doi:10.1513/AnnalsATS.201312-432LD
Basma Hesham, Gunji Yoko, Iwasawa Shunichiro, Nelson Amy, Farid Maha, et al. 2014. "Reprogramming of COPD lung fibroblasts through formation of induced pluripotent stem cells." American journal of physiology. Lung cellular and molecular physiology 306 (6) doi:10.1152/ajplung.00255.2013
Tan Lu, Dickens Jennifer A, Demeo Dawn L, Miranda Elena, Perez Juan, et al. 2014. "Circulating polymers in α1-antitrypsin deficiency." The European respiratory journal doi:10.1183/09031936.00111213
Rennard Stephen I, Daughton David M 2014. "Smoking cessation." Clinics in chest medicine 35 (1) doi:10.1016/j.ccm.2013.11.002
McDonald Merry-Lynn N, Diaz Alejandro A, Ross James C, San Jose Estepar Raul, Zhou Linfu, et al. 2014. "Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study." Annals of the American Thoracic Society 11 (3) doi:10.1513/AnnalsATS.201307-229OC
D'Urzo Anthony D, Rennard Stephen I, Kerwin Edward M, Mergel Victor, Leselbaum Anne R, Caracta Cynthia F 2014. "Efficacy and safety of fixed-dose combinations of aclidinium bromide/formoterol fumarate: the 24-week, randomized, placebo-controlled AUGMENT COPD study." Respiratory research 15 doi:10.1186/s12931-014-0123-0
Hersh Craig P, Make Barry J, Lynch David A, Barr R Graham, Bowler Russell P, et al. 2014. "Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus." BMC pulmonary medicine 14 doi:10.1186/1471-2466-14-164
Putcha Nirupama, Puhan Milo A, Drummond M Bradley, Han MeiLan K, Regan Elizabeth A, et al. 2014. "A simplified score to quantify comorbidity in COPD." PloS one 9 (12) doi:10.1371/journal.pone.0114438
Glass Kimberly, Quackenbush John, Silverman Edwin K, Celli Bartolome, Rennard Stephen I, et al. 2014. "Sexually-dimorphic targeting of functionally-related genes in COPD." BMC systems biology 8 doi:10.1186/s12918-014-0118-y
Liu Xiangde, Nelson Amy, Wang Xingqi, Farid Maha, Gunji Yoko, et al. 2014. "Vitamin D modulates prostaglandin E2 synthesis and degradation in human lung fibroblasts." American journal of respiratory cell and molecular biology 50 (1) doi:10.1165/rcmb.2013-0211OC
O'Neal Wanda K, Anderson Wayne, Basta Patricia V, Carretta Elizabeth E, Doerschuk Claire M, et al. 2014. "Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study." Journal of translational medicine 12 doi:10.1186/1479-5876-12-9
Rennard Stephen I, Sun Shawn X, Tourkodimitris Stavros, Rowe Paul, Goehring Udo M, et al. 2014. "Roflumilast and dyspnea in patients with moderate to very severe chronic obstructive pulmonary disease: a pooled analysis of four clinical trials." International journal of chronic obstructive pulmonary disease 9 doi:10.2147/COPD.S55738
Menche Jörg, Sharma Amitabh, Cho Michael H, Mayer Ruth J, Rennard Stephen I, et al. 2014. "A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease." BMC systems biology 8 Suppl 2 doi:10.1186/1752-0509-8-S2-S8

2013

Rennard Stephen I, Scanlon Paul D, Ferguson Gary T, Rekeda Ludmyla, Maurer Brian T, et al. 2013. "ACCORD COPD II: a randomized clinical trial to evaluate the 12-week efficacy and safety of twice-daily aclidinium bromide in chronic obstructive pulmonary disease patients." Clinical drug investigation 33 (12) doi:10.1007/s40261-013-0138-1
Cheng Donavan T, Kim Deog Kyeom, Cockayne Debra A, Belousov Anton, Bitter Hans, et al. 2013. "Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 188 (8) doi:10.1164/rccm.201302-0247OC
Dodmane Puttappa R, Arnold Lora L, Kakiuchi-Kiyota Satoko, Qiu Fang, Liu Xiangde, et al. 2013. "Cytotoxicity and gene expression changes induced by inorganic and organic trivalent arsenicals in human cells." Toxicology 312 doi:10.1016/j.tox.2013.07.008
Nagahama Kumi Yoneda, Togo Shinsaku, Holz Olaf, Magunussen Helgo, Liu Xiangde, et al. 2013. "Oncostatin M Modulates Fibroblast Function via STAT3." American journal of respiratory cell and molecular biology doi:10.1165/rcmb.2012-0460OC
Ikari Jun, Michalski Joel M, Iwasawa Shunichiro, Gunji Yoko, Nogel Steve, et al. 2013. "Phosphodiesterase 4 Inhibition Augments Human Lung Fibroblast VEGF Production Induced by PGE2." American journal of respiratory cell and molecular biology doi:10.1165/rcmb.2013-0004OC
Zhou Xiaobo, Qiu Weiliang, Sathirapongsasuti J Fah, Cho Michael H, Mancini John D, et al. 2013. "Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cells." Genomics 101 (5) doi:10.1016/j.ygeno.2013.02.010
Farid Maha, Kanaji Nobuhiro, Nakanishi Masanori, Gunji Yoko, Michalski Joel, et al. 2013. "Smad3 mediates cigarette smoke extract (CSE) induction of VEGF release by human fetal lung fibroblasts." Toxicology letters 220 (2) doi:10.1016/j.toxlet.2013.04.011
Siedlinski Mateusz, Tingley Dustin, Lipman Peter J, Cho Michael H, Litonjua Augusto A, et al. 2013. "Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility." Human genetics 132 (4) doi:10.1007/s00439-012-1262-3
Coxson Harvey O, Dirksen Asger, Edwards Lisa D, Yates Julie C, Agusti Alvar, et al. 2013. "The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: a prospective analysis from the ECLIPSE study." The Lancet. Respiratory medicine 1 (2) doi:10.1016/S2213-2600(13)70006-7
Rennard Stephen I, Flavin Susan K, Agarwal Prasheen K, Lo Kim Hung, Barnathan Elliot S 2013. "Long-term safety study of infliximab in moderate-to-severe chronic obstructive pulmonary disease." Respiratory medicine 107 (3) doi:10.1016/j.rmed.2012.11.008
Kanaji Nobuhiro, Nelson Amy, Wang Xingqi, Sato Tadashi, Nakanishi Masanori, et al. 2013. "Differential roles of JNK, ERK1/2, and p38 mitogen-activated protein kinases on endothelial cell tissue repair functions in response to tumor necrosis factor-α." Journal of vascular research 50 (2) doi:10.1159/000345525
Fang Qiuhong, Schulte Nancy A, Kim Huijung, Kobayashi Tetsu, Wang Xingqi, et al. 2013. "Effect of budesonide on fibroblast-mediated collagen gel contraction and degradation." Journal of inflammation research 6 doi:10.2147/JIR.S35136
Wang Xingqi, Nelson Amy, Weiler Zachary M, Patil Amol, Sato Tadashi, et al. 2013. "Anti-inflammatory effects of budesonide in human lung fibroblast are independent of histone deacetylase 2." Journal of inflammation research 6 doi:10.2147/JIR.S43736
Fang Qiuhong, Ma Yingmin, Wang Jing, Michalski Joel, Rennard Stephen I, Liu Xiangde 2013. "PGE 2 desensitizes β -agonist effect on human lung fibroblast-mediated collagen gel contraction through upregulating PDE4." Mediators of inflammation 2013 doi:10.1155/2013/145197

2012

Wan Emily S, Qiu Weiliang, Baccarelli Andrea, Carey Vincent J, Bacherman Helene, et al. 2012. "Systemic steroid exposure is associated with differential methylation in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 186 (12) doi:10.1164/rccm.201207-1280OC
Michalski Joel, Kanaji Nobuhiro, Liu Xiangde, Nogel Steve, Wang Xingqi, et al. 2012. "Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4." American journal of respiratory cell and molecular biology 47 (6) doi:10.1165/rcmb.2012-0057OC
Siedlinski Mateusz, Klanderman Barbara, Sandhaus Robert A, Barker Alan F, Brantly Mark L, et al. 2012. "Association of cigarette smoking and CRP levels with DNA methylation in α-1 antitrypsin deficiency." Epigenetics : official journal of the DNA Methylation Society 7 (7) doi:10.4161/epi.20319
Wan Emily S, Qiu Weiliang, Baccarelli Andrea, Carey Vincent J, Bacherman Helene, et al. 2012. "Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome." Human molecular genetics 21 (13) doi:10.1093/hmg/dds135
Kanaji Nobuhiro, Nelson Amy, Allen-Gipson Diane S, Sato Tadashi, Nakanishi Masanori, et al. 2012. "The p38 mitogen-activated protein kinases modulate endothelial cell survival and tissue repair." Inflammation research : official journal of the European Histamine Research Society ... [et al.] 61 (3) doi:10.1007/s00011-011-0405-7
D'Alessandro-Gabazza Corina N, Kobayashi Tetsu, Boveda-Ruiz Daniel, Takagi Takehiro, Toda Masaaki, et al. 2012. "Development and preclinical efficacy of novel transforming growth factor-β1 short interfering RNAs for pulmonary fibrosis." American journal of respiratory cell and molecular biology 46 (3) doi:10.1165/rcmb.2011-0158OC
Nakanishi Masanori, Sato Tadashi, Li Yingji, Nelson Amy J, Farid Maha, et al. 2012. "Prostaglandin E2 stimulates the production of vascular endothelial growth factor through the E-prostanoid-2 receptor in cultured human lung fibroblasts." American journal of respiratory cell and molecular biology 46 (2) doi:10.1165/rcmb.2010-0115OC
Kim Woo Jin, Wood Alice M, Barker Alan F, Brantly Mark L, Campbell Edward J, et al. 2012. "Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency." Respiratory research 13 doi:10.1186/1465-9921-13-16
Loza Matthew J, Watt Rosemary, Baribaud Frédéric, Barnathan Elliot S, Rennard Stephen I 2012. "Systemic inflammatory profile and response to anti-tumor necrosis factor therapy in chronic obstructive pulmonary disease." Respiratory research 13 doi:10.1186/1465-9921-13-12
Al-shair Khaled, Muellerova Hana, Yorke Janelle, Rennard Stephen I, Wouters Emiel F M, et al. 2012. "Examining fatigue in COPD: development, validity and reliability of a modified version of FACIT-F scale." Health and quality of life outcomes 10 doi:10.1186/1477-7525-10-100
Jen Rachel, Rennard Stephen I, Sin Don D 2012. "Effects of inhaled corticosteroids on airway inflammation in chronic obstructive pulmonary disease: a systematic review and meta-analysis." International journal of chronic obstructive pulmonary disease 7 doi:10.2147/COPD.S32765
Agustí Alvar, Edwards Lisa D, Rennard Stephen I, MacNee William, Tal-Singer Ruth, et al. 2012. "Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype." PloS one 7 (5) doi:10.1371/journal.pone.0037483

2011

Hughes John R, Russ Cristina I, Arteaga Carmen E, Rennard Stephen I 2011. "Efficacy of a flexible quit date versus an a priori quit date approach to smoking cessation: a cross-study analysis." Addictive behaviors 36 (12) doi:10.1016/j.addbeh.2011.08.001
Hughes John R, Rennard Stephen I, Fingar James R, Talbot Sandy K, Callas Peter W, Fagerstrom Karl O 2011. "Efficacy of varenicline to prompt quit attempts in smokers not currently trying to quit: a randomized placebo-controlled trial." Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 13 (10) doi:10.1093/ntr/ntr103
Siedlinski Mateusz, Cho Michael H, Bakke Per, Gulsvik Amund, Lomas David A, et al. 2011. "Genome-wide association study of smoking behaviours in patients with COPD." Thorax 66 (10) doi:10.1136/thoraxjnl-2011-200154
Vestbo Jørgen, Edwards Lisa D, Scanlon Paul D, Yates Julie C, Agusti Alvar, et al. 2011. "Changes in forced expiratory volume in 1 second over time in COPD." The New England journal of medicine 365 (13) doi:10.1056/NEJMoa1105482
Martinez Fernando J, Donohue James F, Rennard Stephen I 2011. "The future of chronic obstructive pulmonary disease treatment--difficulties of and barriers to drug development." Lancet 378 (9795) doi:10.1016/S0140-6736(11)61047-7
Rennard Stephen I 2011. "COPD heterogeneity: what this will mean in practice." Respiratory care 56 (8) doi:10.4187/respcare.01419
Rennard Stephen I, Wachenfeldt Karin von 2011. "Rationale and emerging approaches for targeting lung repair and regeneration in the treatment of chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 8 (4) doi:10.1513/pats.201102-019RM
Celli Bartolome R, Tashkin Donald P, Rennard Stephen I, McElhattan Jennifer, Martin Ubaldo J 2011. "Bronchodilator responsiveness and onset of effect with budesonide/formoterol pMDI in COPD." Respiratory medicine 105 (8) doi:10.1016/j.rmed.2011.02.020
Chapman Kenneth R, Rennard Stephen I, Dogra Angeli, Owen Roger, Lassen Cheryl, Kramer Benjamin 2011. "Long-term safety and efficacy of indacaterol, a long-acting β₂-agonist, in subjects with COPD: a randomized, placebo-controlled study." Chest 140 (1) doi:10.1378/chest.10-1830
MacNee William, Rennard Stephen I, Hunt John F, Edwards Lisa D, Miller Bruce E, et al. 2011. "Evaluation of exhaled breath condensate pH as a biomarker for COPD." Respiratory medicine 105 (7) doi:10.1016/j.rmed.2011.02.009
Sato Tadashi, Liu Xiangde, Basma Hesham, Togo Shinsaku, Sugiura Hisatoshi, et al. 2011. "IL-4 induces differentiation of human embryonic stem cells into fibrogenic fibroblast-like cells." The Journal of allergy and clinical immunology 127 (6) doi:10.1016/j.jaci.2011.01.049
Ding Jianqiang, Yannam Govardhana R, Roy-Chowdhury Namita, Hidvegi Tunda, Basma Hesham, et al. 2011. "Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytes." The Journal of clinical investigation 121 (5) doi:10.1172/JCI45260
Hanania Nicola A, Müllerova Hana, Locantore Nicholas W, Vestbo Jørgen, Watkins Michael L, et al. 2011. "Determinants of depression in the ECLIPSE chronic obstructive pulmonary disease cohort." American journal of respiratory and critical care medicine 183 (5) doi:10.1164/rccm.201003-0472OC
Togo Shinsaku, Sato Tadashi, Sugiura Hisatoshi, Wang Xingqi, Basma Hesham, et al. 2011. "Differentiation of embryonic stem cells into fibroblast-like cells in three-dimensional type I collagen gel cultures." In vitro cellular & developmental biology. Animal 47 (2) doi:10.1007/s11626-010-9367-2
Rennard Stephen I, Calverley Peter M A, Goehring Udo M, Bredenbröker Dirk, Martinez Fernando J 2011. "Reduction of exacerbations by the PDE4 inhibitor roflumilast--the importance of defining different subsets of patients with COPD." Respiratory research 12 doi:10.1186/1465-9921-12-18
Kanaji Nobuhiro, Sato Tadashi, Nelson Amy, Wang Xingqi, Li Yingji, et al. 2011. "Inflammatory cytokines regulate endothelial cell survival and tissue repair functions via NF-κB signaling." Journal of inflammation research 4 doi:10.2147/JIR.S19461
Jones Paul W, Rennard Stephen I, Agusti Alvar, Chanez Pascal, Magnussen Helgo, et al. 2011. "Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease." Respiratory research 12 doi:10.1186/1465-9921-12-55
Li Ying-Ji, Wang Xing-Qi, Sato Tadashi, Kanaji Nobuhiro, Nakanishi Masanori, et al. 2011. "Prostaglandin E₂ inhibits human lung fibroblast chemotaxis through disparate actions on different E-prostanoid receptors." American journal of respiratory cell and molecular biology 44 (1) doi:10.1165/rcmb.2009-0163OC
Rennard Stephen I 2011. "Pathogenesis of chronic obstructive pulmonary disease." Pneumonologia i alergologia polska 79 (2) doi:
Yentes Jennifer M, Sayles Harlan, Meza Jane, Mannino David M, Rennard Stephen I, Stergiou Nicholas 2011. "Walking abnormalities are associated with COPD: An investigation of the NHANES III dataset." Respiratory medicine 105 (1) doi:10.1016/j.rmed.2010.06.007

2010

Togo Shinsaku, Sugiura Hisa, Nelson Amy, Kobayashi Tetsu, Wang Xingqi, et al. 2010. "Hepatic growth factor (HGF) inhibits cigarette smoke extract induced apoptosis in human bronchial epithelial cells." Experimental cell research 316 (20) doi:10.1016/j.yexcr.2010.09.006
Simet Samantha M, Sisson Joseph H, Pavlik Jacqueline A, Devasure Jane M, Boyer Craig, et al. 2010. "Long-term cigarette smoke exposure in a mouse model of ciliated epithelial cell function." American journal of respiratory cell and molecular biology 43 (6) doi:10.1165/rcmb.2009-0297OC
Sørheim Inga-Cecilie, Bakke Per, Gulsvik Amund, Pillai Sreekumar G, Johannessen Ane, et al. 2010. "α₁-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts." Chest 138 (5) doi:10.1378/chest.10-0746
Sato Tadashi, Liu Xiangde, Nelson Amy, Nakanishi Masanori, Kanaji Nobuhiro, et al. 2010. "Reduced miR-146a increases prostaglandin E₂in chronic obstructive pulmonary disease fibroblasts." American journal of respiratory and critical care medicine 182 (8) doi:10.1164/rccm.201001-0055OC
Han MeiLan K, Agusti Alvar, Calverley Peter M, Celli Bartolome R, Criner Gerard, et al. 2010. "Chronic obstructive pulmonary disease phenotypes: the future of COPD." American journal of respiratory and critical care medicine 182 (5) doi:10.1164/rccm.200912-1843CC
Hersh Craig P, Pillai Sreekumar G, Zhu Guohua, Lomas David A, Bakke Per, et al. 2010. "Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene." American journal of respiratory and critical care medicine 182 (5) doi:10.1164/rccm.200910-1586OC
Gross Nicholas J, Giembycz Mark A, Rennard Stephen I 2010. "Treatment of chronic obstructive pulmonary disease with roflumilast, a new phosphodiesterase 4 inhibitor." COPD 7 (2) doi:10.3109/15412551003758304
Chandler Michael A, Rennard Stephen I 2010. "Smoking cessation." Chest 137 (2) doi:10.1378/chest.09-0124

2009

Sugiura Hisatoshi, Ichikawa Tomohiro, Liu Xiangde, Kobayashi Tetsu, Wang Xing Qi, et al. 2009. "N-acetyl-L-cysteine inhibits TGF-beta1-induced profibrotic responses in fibroblasts." Pulmonary pharmacology & therapeutics 22 (6) doi:10.1016/j.pupt.2009.04.002
Maciewicz Rose A, Warburton David, Rennard Stephen I 2009. "Can increased understanding of the role of lung development and aging drive new advances in chronic obstructive pulmonary disease?" Proceedings of the American Thoracic Society 6 (7) doi:10.1513/pats.200908-094RM
Sin Don D, Tashkin Donald, Zhang Xuekui, Radner Finn, Sjöbring Ulf, et al. 2009. "Budesonide and the risk of pneumonia: a meta-analysis of individual patient data." Lancet 374 (9691) doi:10.1016/S0140-6736(09)61250-2
Togo Shinsaku, Liu Xiangde, Wang Xingqi, Sugiura Hisatoshi, Kamio Koichiro, et al. 2009. "PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1-stimulated fibroblasts." American journal of physiology. Lung cellular and molecular physiology 296 (6) doi:10.1152/ajplung.00508.2007
Barr R Graham, Celli Bartolome R, Mannino David M, Petty Thomas, Rennard Stephen I, et al. 2009. "Comorbidities, patient knowledge, and disease management in a national sample of patients with COPD." The American journal of medicine 122 (4) doi:10.1016/j.amjmed.2008.09.042
Pillai Sreekumar G, Ge Dongliang, Zhu Guohua, Kong Xiangyang, Shianna Kevin V, et al. 2009. "A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci." PLoS genetics 5 (3) doi:10.1371/journal.pgen.1000421
Liu Xiangde, Nelson Amy, Wang Xingqi, Kanaji Nobuhiro, Kim Miok, et al. 2009. "MicroRNA-146a modulates human bronchial epithelial cell survival in response to the cytokine-induced apoptosis." Biochemical and biophysical research communications 380 (1) doi:10.1016/j.bbrc.2009.01.066
Kikuchi Kazuhiko, Kohyama Tadashi, Yamauchi Yasuhiro, Kato Jun, Takami Kazutaka, et al. 2009. "C-reactive protein modulates human lung fibroblast migration." Experimental lung research 35 (1) doi:10.1080/01902140802404138
Rennard Stephen I, Tashkin Donald P, McElhattan Jennifer, Goldman Mitchell, Ramachandran Sulabha, et al. 2009. "Efficacy and tolerability of budesonide/formoterol in one hydrofluoroalkane pressurized metered-dose inhaler in patients with chronic obstructive pulmonary disease: results from a 1-year randomized controlled clinical trial." Drugs 69 (5) doi:10.2165/00003495-200969050-00004

2008

Rennard Stephen I, Vestbo Jørgen 2008. "Natural histories of chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 5 (9) doi:10.1513/pats.200804-035QC
Rennard Stephen I 2008. "Lessons from multidisciplinary cross-fertilization: chronic obstructive pulmonary disease, lung cancer, and heart disease." Proceedings of the American Thoracic Society 5 (8) doi:10.1513/pats.200807-060TH
Rennard Stephen I, Vestbo Jørgen 2008. "The many "small COPDs": COPD should be an orphan disease." Chest 134 (3) doi:10.1378/chest.07-3059
Hashimoto Mitsu, Wang Xingqi, Mao Lijun, Kobayashi Tetsu, Kawasaki Shin, et al. 2008. "Sphingosine 1-phosphate potentiates human lung fibroblast chemotaxis through the S1P2 receptor." American journal of respiratory cell and molecular biology 39 (3) doi:10.1165/rcmb.2006-0427OC
Patel Bipen D, Coxson Harvey O, Pillai Sreekumar G, Agustí Alvar G N, Calverley Peter M A, et al. 2008. "Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 178 (5) doi:10.1164/rccm.200801-059OC
Togo Shinsaku, Holz Olaf, Liu Xiangde, Sugiura Hisatoshi, Kamio Koichiro, et al. 2008. "Lung fibroblast repair functions in patients with chronic obstructive pulmonary disease are altered by multiple mechanisms." American journal of respiratory and critical care medicine 178 (3) doi:10.1164/rccm.200706-929OC
Kamio Koichiro, Sato Tadashi, Liu Xiangde, Sugiura Hisatoshi, Togo Shinsaku, et al. 2008. "Prostacyclin analogs stimulate VEGF production from human lung fibroblasts in culture." American journal of physiology. Lung cellular and molecular physiology 294 (6) doi:10.1152/ajplung.00129.2007
Fang Qiuhong, Mao Lijun, Kobayashi Tetsu, Wang Xingqi, Wyatt Todd A, et al. 2008. "PKCdelta mediates thrombin-augmented fibroblast-mediated collagen gel contraction." Biochemical and biophysical research communications 369 (4) doi:10.1016/j.bbrc.2008.03.016
Wardyn Gina G, Rennard Stephen I, Brusnahan Susan K, McGuire Timothy R, Carlson Mary L, et al. 2008. "Effects of exercise on hematological parameters, circulating side population cells, and cytokines." Experimental hematology 36 (2) doi:10.1016/j.exphem.2007.10.003
Tashkin Donald P, Rennard Stephen I, Martin Paula, Ramachandran Sulabha, Martin Ubaldo J, et al. 2008. "Efficacy and safety of budesonide and formoterol in one pressurized metered-dose inhaler in patients with moderate to very severe chronic obstructive pulmonary disease: results of a 6-month randomized clinical trial." Drugs 68 (14) doi:
Houfek Julia Fisco, Atwood Jan R, Wolfe Rhonda M, Agrawal Sangeeta, Reiser Gwendolyn M, et al. 2008. "Knowledge and beliefs about genetics and smoking among visitors and staff at a health care facility." Public health nursing (Boston, Mass.) 25 (1) doi:10.1111/j.1525-1446.2008.00682.x
Merchant Deepali, Ertl Ronald L, Rennard Stephen I, Stanley David W, Miller Jon S 2008. "Eicosanoids mediate insect hemocyte migration." Journal of insect physiology 54 (1) doi:10.1016/j.jinsphys.2007.09.004
Demeo Dawn L, Campbell Edward J, Barker Alan F, Brantly Mark L, Eden Edward, et al. 2008. "IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency." American journal of respiratory cell and molecular biology 38 (1) doi:10.1165/rcmb.2007-0107OC

2007

Rennard Stephen I, Higenbottam Tim 2007. "Exacerbation-free COPD: a goal too far?" Proceedings of the American Thoracic Society 4 (8) doi:10.1513/pats.200707-098TH
Ohnishi Takamasa, Arnold Lora L, He Jun, Clark Nicole M, Kawasaki Shin, et al. 2007. "Inhalation of tobacco smoke induces increased proliferation of urinary bladder epithelium and endothelium in female C57BL/6 mice." Toxicology 241 (1-2) doi:10.1016/j.tox.2007.08.088
Sugiura Hisatoshi, Liu Xiangde, Duan Fenghai, Kawasaki Shin, Togo Shinsaku, et al. 2007. "Cultured lung fibroblasts from ovalbumin-challenged "asthmatic" mice differ functionally from normal." American journal of respiratory cell and molecular biology 37 (4) doi:10.1165/rcmb.2007-0089OC
Calverley Peter M A, Rennard Stephen I 2007. "What have we learned from large drug treatment trials in COPD?" Lancet 370 (9589) doi:10.1016/S0140-6736(07)61381-6
Liu Xiangde, Das Anuk M, Seideman Jonathan, Griswold Don, Afuh Chantal N, et al. 2007. "The CC chemokine ligand 2 (CCL2) mediates fibroblast survival through IL-6." American journal of respiratory cell and molecular biology 37 (1) doi:10.1165/rcmb.2005-0253OC
Kamio Koichiro, Liu Xiangde, Sugiura Hisatoshi, Togo Shinsaku, Kobayashi Tetsu, et al. 2007. "Prostacyclin analogs inhibit fibroblast contraction of collagen gels through the cAMP-PKA pathway." American journal of respiratory cell and molecular biology 37 (1) doi:10.1165/rcmb.2007-0009OC
Rennard Stephen I, Fogarty Charles, Kelsen Steven, Long William, Ramsdell Joe, et al. 2007. "The safety and efficacy of infliximab in moderate to severe chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 175 (9) doi:10.1164/rccm.200607-995OC
Foster Jill A, Yawn Barbara P, Maziar Abdolrasulnia, Jenkins Todd, Rennard Stephen I, Casebeer Linda 2007. "Enhancing COPD management in primary care settings." MedGenMed : Medscape general medicine 9 (3) doi:
Sugiura Hisatoshi, Liu Xiangde, Togo Shinsaku, Kobayashi Tetsu, Shen Lei, et al. 2007. "Prostaglandin E(2) protects human lung fibroblasts from cigarette smoke extract-induced apoptosis via EP(2) receptor activation." Journal of cellular physiology 210 (1) doi:10.1002/jcp.20825

2006

Fang Qiuhong, Liu Xiangde, Al-Mugotir Mona, Kobayashi Tetsu, Abe Shinji, et al. 2006. "Thrombin and TNF-alpha/IL-1beta synergistically induce fibroblast-mediated collagen gel degradation." American journal of respiratory cell and molecular biology 35 (6) doi:10.1165/rcmb.2005-0026OC
Rennard Stephen I, Togo Shinsaku, Holz Olaf 2006. "Cigarette smoke inhibits alveolar repair: a mechanism for the development of emphysema." Proceedings of the American Thoracic Society 3 (8) doi:10.1513/pats.200605-121SF
Rennard Stephen I, Glover Elbert D, Leischow Scott, Daughton David M, Glover Penny N, et al. 2006. "Efficacy of the nicotine inhaler in smoking reduction: A double-blind, randomized trial." Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 8 (4) doi:10.1080/14622200600789916
Hatsukami Dorothy K, Benowitz Neal L, Rennard Stephen I, Oncken Cheryl, Hecht Stephen S 2006. "Biomarkers to assess the utility of potential reduced exposure tobacco products." Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 8 (4) doi:10.1080/14622200600858166
Kapoun Ann M, Gaspar Nicholas J, Wang Ying, Damm Debby, Liu Yu-Wang, et al. 2006. "Transforming growth factor-beta receptor type 1 (TGFbetaRI) kinase activity but not p38 activation is required for TGFbetaRI-induced myofibroblast differentiation and profibrotic gene expression." Molecular pharmacology 70 (2) doi:10.1124/mol.105.021600
Gonzales David, Rennard Stephen I, Nides Mitchell, Oncken Cheryl, Azoulay Salomon, et al. 2006. "Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial." JAMA : the journal of the American Medical Association 296 (1) doi:10.1001/jama.296.1.47
Arany Praveen R, Flanders Kathleen C, Kobayashi Tetsu, Kuo Catherine K, Stuelten Christina, et al. 2006. "Smad3 deficiency alters key structural elements of the extracellular matrix and mechanotransduction of wound closure." Proceedings of the National Academy of Sciences of the United States of America 103 (24) doi:10.1073/pnas.0602473103
Sugiura Hisatoshi, Liu Xiangde, Kobayashi Tetsu, Togo Shinsaku, Ertl Ronald F, et al. 2006. "Reactive nitrogen species augment fibroblast-mediated collagen gel contraction, mediator production, and chemotaxis." American journal of respiratory cell and molecular biology 34 (5) doi:10.1165/rcmb.2005-0339OC
Rennard Stephen I 2006. "Chronic obstructive pulmonary disease: linking outcomes and pathobiology of disease modification." Proceedings of the American Thoracic Society 3 (3) doi:10.1513/pats.200512-129SF
Hatsukami Dorothy K, Benowitz Neal L, Rennard Stephen I, Oncken Cheryl, Hecht Stephen S 2006. "Biomarkers to assess the utility of potential reduced exposure tobacco products." Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 8 (2) doi:10.1080/14622200600576628
Kobayashi Tetsu, Liu Xiangde, Wen Fu-Qiang, Kohyama Tadashi, Shen Lei, et al. 2006. "Smad3 mediates TGF-beta1-induced collagen gel contraction by human lung fibroblasts." Biochemical and biophysical research communications 339 (1) doi:10.1016/j.bbrc.2005.10.209
Rennard Stephen I, Schachter Neil, Strek Mary, Rickard Kathy, Amit Ohad 2006. "Cilomilast for COPD: results of a 6-month, placebo-controlled study of a potent, selective inhibitor of phosphodiesterase 4." Chest 129 (1) doi:10.1378/chest.129.1.56

2005

Celli Bartolome R, Calverley Peter M A, Rennard Stephen I, Wouters Emiel F M, Agusti Alvar, et al. 2005. "Proposal for a multidimensional staging system for chronic obstructive pulmonary disease." Respiratory medicine 99 (12) doi:10.1016/j.rmed.2005.03.019
Barr R Graham, Celli Bartolome R, Martinez Fernando J, Ries Andrew L, Rennard Stephen I, et al. 2005. "Physician and patient perceptions in COPD: the COPD Resource Network Needs Assessment Survey." The American journal of medicine 118 (12) doi:10.1016/j.amjmed.2005.07.059
Kato Jun, Kohyama Tadashi, Okazaki Hitoshi, Desaki Masashi, Nagase Takahide, et al. 2005. "Leukotriene D4 potentiates fibronectin-induced migration of human lung fibroblasts." Clinical immunology (Orlando, Fla.) 117 (2) doi:10.1016/j.clim.2005.07.003
Liu Xiangde, Conner Heather, Kobayashi Tetsu, Kim Huijung, Wen Fuqiang, et al. 2005. "Cigarette smoke extract induces DNA damage but not apoptosis in human bronchial epithelial cells." American journal of respiratory cell and molecular biology 33 (2) doi:10.1165/rcmb.2003-0341OC
Freeman Thomas L, Haver Alvin, Duryee Michael J, Tuma Dean J, Klassen Lynell W, et al. 2005. "Aldehydes in cigarette smoke react with the lipid peroxidation product malonaldehyde to form fluorescent protein adducts on lysines." Chemical research in toxicology 18 (5) doi:10.1021/tx0500676
Spurzem John R, Rennard Stephen I 2005. "Pathogenesis of COPD." Seminars in respiratory and critical care medicine 26 (2) doi:10.1055/s-2005-869535
Rennard Stephen I 2005. "Minimal clinically important difference, clinical perspective: an opinion." COPD 2 (1) doi:
Kobayashi Tetsu, Liu Xiangde, Wen Fu-Qiang, Fang Qiuhong, Abe Shinji, et al. 2005. "Smad3 mediates TGF-beta1 induction of VEGF production in lung fibroblasts." Biochemical and biophysical research communications 327 (2) doi:10.1016/j.bbrc.2004.12.032
Kobayashi Tetsu, Liu Xiangde, Kim Hui Jung, Kohyama Tadashi, Wen Fu-Qiang, et al. 2005. "TGF-beta1 and serum both stimulate contraction but differentially affect apoptosis in 3D collagen gels." Respiratory research 6 doi:10.1186/1465-9921-6-141
Rennard Stephen I, Stoner Julie A 2005. "Challenges and opportunities for combination therapy in chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 2 (4) doi:10.1513/pats.200504-046SR
Rennard Stephen I 2005. "Clinical approach to patients with chronic obstructive pulmonary disease and cardiovascular disease." Proceedings of the American Thoracic Society 2 (1) doi:10.1513/pats.200410-051SF

2004

Abe Shinji, Boyer Craig, Liu Xiangde, Wen Fu Qiang, Kobayashi Tetsu, et al. 2004. "Cells derived from the circulation contribute to the repair of lung injury." American journal of respiratory and critical care medicine 170 (11) doi:10.1164/rccm.200307-908OC
Kim Huijung, Liu Xiangde, Kobayashi Tetsu, Conner Heather, Kohyama Tadashi, et al. 2004. "Reversible cigarette smoke extract-induced DNA damage in human lung fibroblasts." American journal of respiratory cell and molecular biology 31 (5) doi:10.1165/rcmb.2002-0300OC
Ohta Ken, Fukuchi Yoshinosuke, Grouse Lawrence, Mizutani Ryuji, Rabe Klaus F, et al. 2004. "A prospective clinical study of theophylline safety in 3810 elderly with asthma or COPD." Respiratory medicine 98 (10) doi:
Wen Fu-Qiang, Liu Xiangde, Kobayashi Tetsu, Abe Shinji, Fang Qiuhong, et al. 2004. "Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads." American journal of respiratory cell and molecular biology 30 (6) doi:10.1165/rcmb.2002-0249OC
Kohyama Tadashi, Liu Xiangde, Wen Fu-Qiang, Kobayashi Tetsu, Fang Qiuhong, et al. 2004. "Cytokines modulate cilomilast response in lung fibroblasts." Clinical immunology (Orlando, Fla.) 111 (3) doi:10.1016/j.clim.2004.01.007
Abe Shinji, Lauby Gina, Boyer Craig, Manouilova Lidia, Rennard Stephen I, Sharp J Graham 2004. "Lung cells transplanted to irradiated recipients generate lymphohematopoietic progeny." American journal of respiratory cell and molecular biology 30 (4) doi:10.1165/rcmb.2003-0140OC
Kim Huijung, Liu Xiangde, Kohyama Tadashi, Kobayashi Tetsu, Conner Heather, et al. 2004. "Cigarette smoke stimulates MMP-1 production by human lung fibroblasts through the ERK1/2 pathway." COPD 1 (1) doi:10.1081/COPD-120030164
Kohyama Tadashi, Liu Xiangde, Wen Fu-Qiang, Kobayashi Tetsu, Abe Shinji, Rennard Stephen I 2004. "IL-4 and IL-13 induce chemotaxis of human foreskin fibroblasts, but not human fetal lung fibroblasts." Inflammation 28 (1) doi:
Rennard Stephen I 2004. "Treatment of stable chronic obstructive pulmonary disease." Lancet 364 (9436) doi:10.1016/S0140-6736(04)16941-9
Rennard Stephen I, Farmer Stephen G 2004. "Exacerbations and progression of disease in asthma and chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 1 (2) doi:10.1513/pats.2306026
Rennard Stephen I 2004. "Antiinflammatory therapies other than corticosteroids." Proceedings of the American Thoracic Society 1 (3) doi:10.1513/pats.200402-020MS

2003

Leidy Nancy Kline, Rennard Stephen I, Schmier Jordana, Jones M Kathryn C, Goldman Mitch 2003. "The breathlessness, cough, and sputum scale: the development of empirically based guidelines for interpretation." Chest 124 (6) doi:
Gamble Elizabeth, Grootendorst Diana C, Brightling Christopher E, Troy Susannah, Qiu Yusheng, et al. 2003. "Antiinflammatory effects of the phosphodiesterase-4 inhibitor cilomilast (Ariflo) in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 168 (8) doi:10.1164/rccm.200212-1490OC
Wen Fu-Qiang, Liu Xiangde, Manda Winfred, Terasaki Yusuke, Kobayashi Tetsu, et al. 2003. "TH2 Cytokine-enhanced and TGF-beta-enhanced vascular endothelial growth factor production by cultured human airway smooth muscle cells is attenuated by IFN-gamma and corticosteroids." The Journal of allergy and clinical immunology 111 (6) doi:
Liu Xiangde, Kohyama Tadashi, Kobayashi Tetsu, Abe Shinji, Kim Hui Jung, et al. 2003. "Cigarette smoke extract inhibits chemotaxis and collagen gel contraction mediated by human bone marrow osteoprogenitor cells and osteoblast-like cells." Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 14 (3) doi:10.1007/s00198-002-1350-7
Liu Xiangde, Wen Fu-Qiang, Kobayashi Tetsu, Abe Shinji, Fang Qiuhong, et al. 2003. "Smad3 mediates the TGF-beta-induced contraction of type I collagen gels by mouse embryo fibroblasts." Cell motility and the cytoskeleton 54 (3) doi:10.1002/cm.10098
Wen Fu-Qiang, Kohyama Tadashi, Sköld C Magnus, Zhu Yun Kiu, Liu Xiangde, et al. 2003. "Glucocorticoids modulate TGF-beta production by human fetal lung fibroblasts." Inflammation 27 (1) doi:
Smith Stevens S, Jorenby Douglas E, Leischow Scott J, Nides Mitchell A, Rennard Stephen I, et al. 2003. "Targeting smokers at increased risk for relapse: treating women and those with a history of depression." Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 5 (1) doi:
Wang Hangjun, Liu Xiangde, Umino Takeshi, Kohyama Tadashi, Zhu Yun Kui, et al. 2003. "Effect of cigarette smoke on fibroblast-mediated gel contraction is dependent on cell density." American journal of physiology. Lung cellular and molecular physiology 284 (1) doi:10.1152/ajplung.00042.2002
Kim Huijung, Liu Xiangde, Kobayashi Tetsu, Kohyama Tadashi, Wen Fu-Qiang, et al. 2003. "Ultrafine carbon black particles inhibit human lung fibroblast-mediated collagen gel contraction." American journal of respiratory cell and molecular biology 28 (1) doi:10.1165/rcmb.4796
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