Rahman Irfan

Top coauthors of Rahman Irfan

Yao Hongwei (53 papers)

Sundar Isaac K (45 papers)

Rajendrasozhan Saravanan (17 papers)

Yang Se-Ran (16 papers)

Caito Samuel (14 papers)

List of Rahman Irfan publications

2017

Tang Maoping, Ji Changyi, Pallo Susanne, Rahman Irfan, Johnson Gail V W 2017. "Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner." Neurobiology of aging 63 doi:10.1016/j.neurobiolaging.2017.12.001
Sundar Isaac K, Rashid Kahkashan, Sellix Michael T, Rahman Irfan 2017. "The nuclear receptor and clock gene REV-ERBα regulates cigarette smoke-induced lung inflammation." Biochemical and biophysical research communications 493 (4) doi:10.1016/j.bbrc.2017.09.157
Sundar Isaac K, Sellix Michael T, Rahman Irfan 2017. "Redox regulation of circadian molecular clock in chronic airway diseases." Free radical biology & medicine doi:10.1016/j.freeradbiomed.2017.10.383
Javed Fawad, Abduljabbar Tariq, Vohra Fahim, Malmstrom Hans, Rahman Irfan, Romanos Georgios E 2017. "Comparison of Periodontal Parameters and Self-Perceived Oral Symptoms Among Cigarette Smokers, Individuals Vaping Electronic Cigarettes, and Never-Smokers." Journal of periodontology 88 (10) doi:10.1902/jop.2017.170197
Javed Fawad, ALHarthi Shatha Subhi, BinShabaib Munerah Saleh, Gajendra Sangeeta, Romanos Georgios E, Rahman Irfan 2017. "Toxicological impact of waterpipe smoking and flavorings in the oral cavity and respiratory system." Inhalation toxicology 29 (9) doi:10.1080/08958378.2017.1384084
Behrsing Holger, Hill Erin, Raabe Hans, Tice Raymond, Fitzpatrick Suzanne, et al. 2017. "In vitro exposure systems and dosimetry assessment tools for inhaled tobacco products: Workshop proceedings, conclusions and paths forward for in vitro model use." Alternatives to laboratory animals : ATLA 45 (3) doi:
Lee Hanbyeol, Park Jeong-Ran, Kim Woo Jin, Sundar Isaac K, Rahman Irfan, et al. 2017. "Blockade of RAGE ameliorates elastase-induced emphysema development and progression via RAGE-DAMP signaling." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 31 (5) doi:10.1096/fj.201601155R
Lei Wei, Lerner Chad, Sundar Isaac K, Rahman Irfan 2017. "Myofibroblast differentiation and its functional properties are inhibited by nicotine and e-cigarette via mitochondrial OXPHOS complex III." Scientific reports 7 doi:10.1038/srep43213
Gerloff Janice, Sundar Isaac K, Freter Robert, Sekera Emily R, Friedman Alan E, et al. 2017. "Inflammatory Response and Barrier Dysfunction by Different e-Cigarette Flavoring Chemicals Identified by Gas Chromatography-Mass Spectrometry in e-Liquids and e-Vapors on Human Lung Epithelial Cells and Fibroblasts." Applied in vitro toxicology 3 (1) doi:10.1089/aivt.2016.0030
Arbat Sameer, Dave Mitesh, Niranjane Vinit, Rahman Irfan, Arbat Ashok 2017. "Analyzing the clinical profile of swine flu/influenza A H1N1 infection in central India: a retrospective study." Virusdisease 28 (1) doi:10.1007/s13337-017-0363-y
Sundar Isaac K, Yin Qiangzong, Baier Brian S, Yan Li, Mazur Witold, et al. 2017. "DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD." Clinical epigenetics 9 doi:10.1186/s13148-017-0335-5

2016

Sundar Isaac Kirubakaran, Rahman Irfan 2016. "Gene expression profiling of epigenetic chromatin modification enzymes and histone marks by cigarette smoke: Implications for COPD and lung cancer." American journal of physiology. Lung cellular and molecular physiology doi:10.1152/ajplung.00253.2016
Sundar Isaac K, Javed Fawad, Romanos Georgios E, Rahman Irfan 2016. "E-cigarettes and flavorings induce inflammatory and pro-senescence responses in oral epithelial cells and periodontal fibroblasts." Oncotarget doi:10.18632/oncotarget.12857
Ahmad Tanveer, Sundar Isaac K, Tormos Ana M, Lerner Chad A, Gerloff Janice, et al. 2016. "Shelterin TPP1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirt1 Deacetylase in Chronic Obstructive Pulmonary Disease." American journal of respiratory cell and molecular biology doi:10.1165/rcmb.2016-0198OC
Lerner Chad A, Sundar Isaac K, Rahman Irfan 2016. "Mitochondrial redox system, dynamics, and dysfunction in lung inflammaging and COPD." The international journal of biochemistry & cell biology doi:10.1016/j.biocel.2016.07.026
Lerner Chad A, Rutagarama Pierrot, Ahmad Tanveer, Sundar Isaac K, Elder Alison, Rahman Irfan 2016. "Electronic cigarette aerosols and copper nanoparticles induce mitochondrial stress and promote DNA fragmentation in lung fibroblasts." Biochemical and biophysical research communications doi:10.1016/j.bbrc.2016.06.109
Pagano Todd, DiFrancesco A Gary, Smith Susan B, George Jerrin, Wink Gloria, et al. 2016. "Determination of Nicotine Content and Delivery in Disposable Electronic Cigarettes Available in the United States by Gas Chromatography-Mass Spectrometry." Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 18 (5) doi:10.1093/ntr/ntv120
Javed Fawad, Al-Kheraif Abdulaziz A, Rahman Irfan, Millan-Luongo Lorena Teresa, Feng Changyong, et al. 2016. "Comparison of Clinical and Radiographic Periodontal Status Between Habitual Water-Pipe Smokers and Cigarette Smokers." Journal of periodontology 87 (2) doi:10.1902/jop.2015.150235
Lerner Chad A, Lei Wei, Sundar Isaac K, Rahman Irfan 2016. "Genetic Ablation of CXCR2 Protects against Cigarette Smoke-Induced Lung Inflammation and Injury." Frontiers in pharmacology 7 doi:10.3389/fphar.2016.00391

2015

Yao Hongwei, Sundar Isaac K, Huang Yadi, Gerloff Janice, Sellix Michael T, et al. 2015. "Disruption of Sirtuin 1-Mediated Control of Circadian Molecular Clock and Inflammation in Chronic Obstructive Pulmonary Disease." American journal of respiratory cell and molecular biology 53 (6) doi:10.1165/rcmb.2014-0474OC
Sundar Isaac K, Yao Hongwei, Sellix Michael T, Rahman Irfan 2015. "Circadian molecular clock in lung pathophysiology." American journal of physiology. Lung cellular and molecular physiology 309 (10) doi:10.1152/ajplung.00152.2015
Sundar Isaac K, Yao Hongwei, Sellix Michael T, Rahman Irfan 2015. "Circadian clock-coupled lung cellular and molecular functions in chronic airway diseases." American journal of respiratory cell and molecular biology 53 (3) doi:10.1165/rcmb.2014-0476TR
Ahmad Tanveer, Sundar Isaac K, Lerner Chad A, Gerloff Janice, Tormos Ana M, et al. 2015. "Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 29 (7) doi:10.1096/fj.14-268276
Lerner Chad A, Sundar Isaac K, Watson Richard M, Elder Alison, Jones Ryan, et al. 2015. "Environmental health hazards of e-cigarettes and their components: Oxidants and copper in e-cigarette aerosols." Environmental pollution (Barking, Essex : 1987) 198 doi:10.1016/j.envpol.2014.12.033
Sundar Isaac K, Ahmad Tanveer, Yao Hongwei, Hwang Jae-woong, Gerloff Janice, et al. 2015. "Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD." Scientific reports 4 doi:10.1038/srep09927
Lerner Chad A, Sundar Isaac K, Yao Hongwei, Gerloff Janice, Ossip Deborah J, et al. 2015. "Vapors produced by electronic cigarettes and e-juices with flavorings induce toxicity, oxidative stress, and inflammatory response in lung epithelial cells and in mouse lung." PloS one 10 (2) doi:10.1371/journal.pone.0116732

2014

Yao Hongwei, Sundar Isaac K, Ahmad Tanveer, Lerner Chad, Gerloff Janice, et al. 2014. "SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism." American journal of physiology. Lung cellular and molecular physiology 306 (9) doi:10.1152/ajplung.00323.2013
Sundar Isaac K, Nevid Michael Z, Friedman Alan E, Rahman Irfan 2014. "Cigarette smoke induces distinct histone modifications in lung cells: implications for the pathogenesis of COPD and lung cancer." Journal of proteome research 13 (2) doi:10.1021/pr400998n
Sundar Isaac K, Yao Hongwei, Huang Yadi, Lyda Elizabeth, Sime Patricia J, et al. 2014. "Serotonin and corticosterone rhythms in mice exposed to cigarette smoke and in patients with COPD: implication for COPD-associated neuropathogenesis." PloS one 9 (2) doi:10.1371/journal.pone.0087999
Hwang Jae-Woong, Sundar Isaac K, Yao Hongwei, Sellix Michael T, Rahman Irfan 2014. "Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 28 (1) doi:10.1096/fj.13-232629
Jo Chulman, Gundemir Soner, Pritchard Susanne, Jin Youngnam N, Rahman Irfan, Johnson Gail V W 2014. "Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52." Nature communications 5 doi:10.1038/ncomms4496

2013

Lam Hilaire C, Cloonan Suzanne M, Bhashyam Abhiram R, Haspel Jeffery A, Singh Anju, et al. 2013. "Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction." The Journal of clinical investigation 123 (12) doi:10.1172/JCI69636
Gilels Felicia, Paquette Stephen T, Zhang Jingyuan, Rahman Irfan, White Patricia M 2013. "Mutation of Foxo3 causes adult onset auditory neuropathy and alters cochlear synapse architecture in mice." The Journal of neuroscience : the official journal of the Society for Neuroscience 33 (47) doi:10.1523/JNEUROSCI.2529-13.2013
Yao Hongwei, Hwang Jae-woong, Sundar Isaac K, Friedman Alan E, McBurney Michael W, et al. 2013. "SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPD." American journal of physiology. Lung cellular and molecular physiology 305 (9) doi:10.1152/ajplung.00249.2012
Sundar Isaac K, Yao Hongwei, Rahman Irfan 2013. "Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases." Antioxidants & redox signaling 18 (15) doi:10.1089/ars.2012.4863
Rahman Irfan 2013. "Retraction: cigarette smoke-induced oxidative/nitrosative stress impairs VEGF- and fluid shear stress-mediated signaling in endothelial cells. Edirisinghe I, Arunachalam G, Wong C, Yao H, Rahman A, Phipps RP, Jin ZG, and Rahman I. Antioxid Redox Signal 12: 1355-1369, 2010." Antioxidants & redox signaling 18 (12) doi:10.1089/ars.2012.5170
Hwang Jae-Woong, Yao Hongwei, Caito Samuel, Sundar Isaac K, Rahman Irfan 2013. "Redox regulation of SIRT1 in inflammation and cellular senescence." Free radical biology & medicine 61C doi:10.1016/j.freeradbiomed.2013.03.015
Yao Hongwei, Sundar Isaac K, Gorbunova Vera, Rahman Irfan 2013. "P21-PARP-1 pathway is involved in cigarette smoke-induced lung DNA damage and cellular senescence." PloS one 8 (11) doi:10.1371/journal.pone.0080007

2012

Yao Hongwei, Rahman Irfan 2012. "Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence." Biochemical pharmacology 84 (10) doi:10.1016/j.bcp.2012.06.031
Agarwal Amit R, Zhao Liqin, Sancheti Harsh, Sundar Isaac K, Rahman Irfan, Cadenas Enrique 2012. "Short-term cigarette smoke exposure induces reversible changes in energy metabolism and cellular redox status independent of inflammatory responses in mouse lungs." American journal of physiology. Lung cellular and molecular physiology 303 (10) doi:10.1152/ajplung.00219.2012
Yao Hongwei, Rahman Irfan 2012. "Role of histone deacetylase 2 in epigenetics and cellular senescence: implications in lung inflammaging and COPD." American journal of physiology. Lung cellular and molecular physiology 303 (7) doi:10.1152/ajplung.00175.2012
Basic Vladimir T, Tadele Elsa, Elmabsout Ali Ateia, Yao Hongwei, Rahman Irfan, et al. 2012. "Exposure to cigarette smoke induces overexpression of von Hippel-Lindau tumor suppressor in mouse skeletal muscle." American journal of physiology. Lung cellular and molecular physiology 303 (6) doi:10.1152/ajplung.00007.2012
Rahman Irfan, MacNee William 2012. "Antioxidant pharmacological therapies for COPD." Current opinion in pharmacology 12 (3) doi:10.1016/j.coph.2012.01.015
Yao Hongwei, Chung Sangwoon, Hwang Jae-woong, Rajendrasozhan Saravanan, Sundar Isaac K, et al. 2012. "SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice." The Journal of clinical investigation 122 (6) doi:10.1172/JCI60132
Yang Se-Ran, Rahman Irfan, Trosko James E, Kang Kyung-Sun 2012. "Oxidative stress-induced biomarkers for stem cell-based chemical screening." Preventive medicine 54 Suppl doi:10.1016/j.ypmed.2011.11.013
Rahman Irfan 2012. "Pharmacological antioxidant strategies as therapeutic interventions for COPD." Biochimica et biophysica acta 1822 (5) doi:10.1016/j.bbadis.2011.11.004
Rahman Irfan, Kinnula Vuokko L 2012. "Strategies to decrease ongoing oxidant burden in chronic obstructive pulmonary disease." Expert review of clinical pharmacology 5 (3) doi:10.1586/ecp.12.16
Rahman Irfan, Kinnula Vuokko L, Gorbunova Vera, Yao Hongwei 2012. "SIRT1 as a therapeutic target in inflammaging of the pulmonary disease." Preventive medicine 54 Suppl doi:10.1016/j.ypmed.2011.11.014
Klionsky Daniel J, Abdalla Fabio C, Abeliovich Hagai, Abraham Robert T, Acevedo-Arozena Abraham, et al. 2012. "Guidelines for the use and interpretation of assays for monitoring autophagy." Autophagy 8 (4) doi:
Sundar Isaac K, Chung Sangwoon, Hwang Jae-Woong, Lapek John D, Bulger Michael, et al. 2012. "Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-κB-dependent genes." PloS one 7 (2) doi:10.1371/journal.pone.0031378

2011

Nadtochiy Sergiy M, Yao Hongwei, McBurney Michael W, Gu Wei, Guarente Leonard, et al. 2011. "SIRT1-mediated acute cardioprotection." American journal of physiology. Heart and circulatory physiology 301 (4) doi:10.1152/ajpheart.00587.2011
Regan Elizabeth A, Mazur Witold, Meoni Eleonora, Toljamo Tuula, Millar Julie, et al. 2011. "Smoking and COPD increase sputum levels of extracellular superoxide dismutase." Free radical biology & medicine 51 (3) doi:10.1016/j.freeradbiomed.2011.05.008
Yao Hongwei, Rahman Irfan 2011. "Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease." Toxicology and applied pharmacology 254 (2) doi:10.1016/j.taap.2009.10.022
Hwang Jae-woong, Rajendrasozhan Saravanan, Yao Hongwei, Chung Sangwoon, Sundar Isaac K, et al. 2011. "FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease." Journal of immunology (Baltimore, Md. : 1950) 187 (2) doi:10.4049/jimmunol.1001861
Sundar Isaac K, Mullapudi Nandita, Yao Hongwei, Spivack Simon D, Rahman Irfan 2011. "Lung cancer and its association with chronic obstructive pulmonary disease: update on nexus of epigenetics." Current opinion in pulmonary medicine 17 (4) doi:10.1097/MCP.0b013e3283477533
Londhe Vedang A, Sundar Isaac K, Lopez Benjamin, Maisonet Tiffany M, Yu Yang, et al. 2011. "Hyperoxia impairs alveolar formation and induces senescence through decreased histone deacetylase activity and up-regulation of p21 in neonatal mouse lung." Pediatric research 69 (5 Pt 1) doi:10.1203/PDR.0b013e318211c917
Sundar Isaac K, Hwang Jae-Woong, Wu Shaoping, Sun Jun, Rahman Irfan 2011. "Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation." Biochemical and biophysical research communications 406 (1) doi:10.1016/j.bbrc.2011.02.011
Nadtochiy Sergiy M, Redman Emily, Rahman Irfan, Brookes Paul S 2011. "Lysine deacetylation in ischaemic preconditioning: the role of SIRT1." Cardiovascular research 89 (3) doi:10.1093/cvr/cvq287
Sundar Isaac K, Rahman Irfan 2011. "Vitamin d and susceptibility of chronic lung diseases: role of epigenetics." Frontiers in pharmacology 2 doi:10.3389/fphar.2011.00050
Chung Sangwoon, Sundar Isaac K, Hwang Jae-Woong, Yull Fiona E, Blackwell Timothy S, et al. 2011. "NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs." PloS one 6 (8) doi:10.1371/journal.pone.0023488

2010

Adenuga David, Caito Samuel, Yao Hongwei, Sundar Isaac K, Hwang Jae-Woong, et al. 2010. "Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction." Biochemical and biophysical research communications 403 (3-4) doi:10.1016/j.bbrc.2010.11.054
Singh Shruti, Vrishni Sonal, Singh Brijesh K, Rahman Irfan, Kakkar Poonam 2010. "Nrf2-ARE stress response mechanism: a control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases." Free radical research 44 (11) doi:10.3109/10715762.2010.507670
Sundar Isaac K, Chung Sangwoon, Hwang Jae-Woong, Arunachalam Gnanapragasam, Cook Suzanne, et al. 2010. "Peroxiredoxin 6 differentially regulates acute and chronic cigarette smoke–mediated lung inflammatory response and injury." Experimental lung research 36 (8) doi:10.3109/01902141003754128
Caito Samuel, Rajendrasozhan Saravanan, Cook Suzanne, Chung Sangwoon, Yao Hongwei, et al. 2010. "SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 24 (9) doi:10.1096/fj.09-151308
Chung Sangwoon, Yao Hongwei, Caito Samuel, Hwang Jae-Woong, Arunachalam Gnanapragasam, Rahman Irfan 2010. "Regulation of SIRT1 in cellular functions: role of polyphenols." Archives of biochemistry and biophysics 501 (1) doi:10.1016/j.abb.2010.05.003
Yao Hongwei, Arunachalam Gnanapragasam, Hwang Jae-Woong, Chung Sangwoon, Sundar Isaac K, et al. 2010. "Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM." Proceedings of the National Academy of Sciences of the United States of America 107 (35) doi:10.1073/pnas.1007625107
Hwang Jae-woong, Chung Sangwoon, Sundar Isaac K, Yao Hongwei, Arunachalam Gnanapragasam, et al. 2010. "Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD." Archives of biochemistry and biophysics 500 (2) doi:10.1016/j.abb.2010.05.013
Chung Sangwoon, Sundar Isaac Kirubakaran, Yao Hongwei, Ho Ye-Shih, Rahman Irfan 2010. "Glutaredoxin 1 regulates cigarette smoke-mediated lung inflammation through differential modulation of I{kappa}B kinases in mice: impact on histone acetylation." American journal of physiology. Lung cellular and molecular physiology 299 (2) doi:10.1152/ajplung.00426.2009
Edirisinghe Indika, Rahman Irfan 2010. "Cigarette smoke-mediated oxidative stress, shear stress, and endothelial dysfunction: role of VEGFR2." Annals of the New York Academy of Sciences 1203 doi:10.1111/j.1749-6632.2010.05601.x
Edirisinghe Indika, Arunachalam Gnanapragasam, Wong Chelsea, Yao Hongwei, Rahman Arshad, et al. 2010. "Cigarette-smoke-induced oxidative/nitrosative stress impairs VEGF- and fluid-shear-stress-mediated signaling in endothelial cells." Antioxidants & redox signaling 12 (12) doi:10.1089/ars.2009.2874
Rajendrasozhan Saravanan, Hwang Jae-Woong, Yao Hongwei, Kishore Nandini, Rahman Irfan 2010. "Anti-inflammatory effect of a selective IkappaB kinase-beta inhibitor in rat lung in response to LPS and cigarette smoke." Pulmonary pharmacology & therapeutics 23 (3) doi:10.1016/j.pupt.2010.01.002
Adenuga David, Rahman Irfan 2010. "Protein kinase CK2-mediated phosphorylation of HDAC2 regulates co-repressor formation, deacetylase activity and acetylation of HDAC2 by cigarette smoke and aldehydes." Archives of biochemistry and biophysics 498 (1) doi:10.1016/j.abb.2010.04.002
Vibhuti Arpana, Arif Ehtesham, Mishra Aastha, Deepak Desh, Singh Bhawani, et al. 2010. "CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD." Clinica chimica acta; international journal of clinical chemistry 411 (7-8) doi:10.1016/j.cca.2009.12.018
Arunachalam Gnanapragasam, Yao Hongwei, Sundar Isaac K, Caito Samuel, Rahman Irfan 2010. "SIRT1 regulates oxidant- and cigarette smoke-induced eNOS acetylation in endothelial cells: Role of resveratrol." Biochemical and biophysical research communications 393 (1) doi:10.1016/j.bbrc.2010.01.080
Yao Hongwei, Hwang Jae-woong, Moscat Jorge, Diaz-Meco Maria T, Leitges Michael, et al. 2010. "Protein kinase C zeta mediates cigarette smoke/aldehyde- and lipopolysaccharide-induced lung inflammation and histone modifications." The Journal of biological chemistry 285 (8) doi:10.1074/jbc.M109.041418
Caito Samuel, Hwang Jae-Woong, Chung Sangwoon, Yao Hongwei, Sundar Isaac K, Rahman Irfan 2010. "PARP-1 inhibition does not restore oxidant-mediated reduction in SIRT1 activity." Biochemical and biophysical research communications 392 (3) doi:10.1016/j.bbrc.2009.12.161
Rajendrasozhan Saravanan, Chung Sangwoon, Sundar Isaac K, Yao Hongwei, Rahman Irfan 2010. "Targeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling." American journal of physiology. Lung cellular and molecular physiology 298 (2) doi:10.1152/ajplung.00265.2009
Marwick John A, Edirisinghe Indika, Arunachalam Gnanapragasam, Stevenson Christopher S, Macnee William, et al. 2010. "Cigarette smoke regulates VEGFR2-mediated survival signaling in rat lungs." Journal of inflammation (London, England) 7 (1) doi:10.1186/1476-9255-7-11
Bancos Simona, Baglole Carolyn J, Rahman Irfan, Phipps Richard P 2010. "Induction of heme oxygenase-1 in normal and malignant B lymphocytes by 15-deoxy-Delta(12,14)-prostaglandin J(2) requires Nrf2." Cellular immunology 262 (1) doi:10.1016/j.cellimm.2009.12.003
Arunachalam Gnanapragasam, Sundar Isaac K, Hwang Jae-Woong, Yao Hongwei, Rahman Irfan 2010. "Emphysema is associated with increased inflammation in lungs of atherosclerosis-prone mice by cigarette smoke: implications in comorbidities of COPD." Journal of inflammation (London, England) 7 doi:10.1186/1476-9255-7-34
Ishikawa Nobuhisa, Ohlmeier Steffen, Salmenkivi Kaisa, Myllärniemi Marjukka, Rahman Irfan, et al. 2010. "Hemoglobin α and β are ubiquitous in the human lung, decline in idiopathic pulmonary fibrosis but not in COPD." Respiratory research 11 doi:10.1186/1465-9921-11-123
Sundar Isaac K, Caito Samuel, Yao Hongwei, Rahman Irfan 2010. "Oxidative stress, thiol redox signaling methods in epigenetics." Methods in enzymology 474 doi:10.1016/S0076-6879(10)74013-1

2009

Zakkar Mustafa, Van der Heiden Kim, Luong Le Anh, Chaudhury Hera, Cuhlmann Simon, et al. 2009. "Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state." Arteriosclerosis, thrombosis, and vascular biology 29 (11) doi:10.1161/ATVBAHA.109.193375
Rajendrasozhan Saravanan, Yao Hongwei, Rahman Irfan 2009. "Current perspectives on role of chromatin modifications and deacetylases in lung inflammation in COPD." COPD 6 (4) doi:
Yao Hongwei, Rahman Irfan 2009. "Current concepts on the role of inflammation in COPD and lung cancer." Current opinion in pharmacology 9 (4) doi:10.1016/j.coph.2009.06.009
Adenuga David, Yao Hongwei, March Thomas H, Seagrave Jeanclare, Rahman Irfan 2009. "Histone deacetylase 2 is phosphorylated, ubiquitinated, and degraded by cigarette smoke." American journal of respiratory cell and molecular biology 40 (4) doi:10.1165/rcmb.2008-0255OC
Yang Se-Ran, Yao Hongwei, Rajendrasozhan Saravanan, Chung Sangwoon, Edirisinghe Indika, et al. 2009. "RelB is differentially regulated by IkappaB Kinase-alpha in B cells and mouse lung by cigarette smoke." American journal of respiratory cell and molecular biology 40 (2) doi:10.1165/rcmb.2008-0207OC
Biswas Saibal K, Rahman Irfan 2009. "Environmental toxicity, redox signaling and lung inflammation: the role of glutathione." Molecular aspects of medicine 30 (1-2) doi:10.1016/j.mam.2008.07.001
Sarir Hadi, Mortaz Esmaeil, Karimi Khalil, Kraneveld Aletta D, Rahman Irfan, et al. 2009. "Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages." Journal of inflammation (London, England) 6 doi:10.1186/1476-9255-6-12

2008

Rahman Irfan 2008. "Antioxidant therapeutic advances in COPD." Therapeutic advances in respiratory disease 2 (6) doi:10.1177/1753465808098224
Debret Romain, Brassart-Pasco Sylvie, Lorin Johanna, Martoriati Alain, Deshorgue Aurelie, et al. 2008. "Ceramide inhibition of MMP-2 expression and human cancer bronchial cell invasiveness involve decreased histone acetylation." Biochimica et biophysica acta 1783 (10) doi:10.1016/j.bbamcr.2008.06.001
Meja Koremu K, Rajendrasozhan Saravanan, Adenuga David, Biswas Saibal K, Sundar Isaac K, et al. 2008. "Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2." American journal of respiratory cell and molecular biology 39 (3) doi:10.1165/rcmb.2008-0012OC
Biswas Saibal, Rahman Irfan 2008. "Modulation of steroid activity in chronic inflammation: a novel anti-inflammatory role for curcumin." Molecular nutrition & food research 52 (9) doi:10.1002/mnfr.200700259
Edirisinghe Indika, Yang Se-Ran, Yao Hongwei, Rajendrasozhan Saravanan, Caito Samuel, et al. 2008. "VEGFR-2 inhibition augments cigarette smoke-induced oxidative stress and inflammatory responses leading to endothelial dysfunction." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 22 (7) doi:10.1096/fj.07-099481
Yao Hongwei, Yang Se-Ran, Edirisinghe Indika, Rajendrasozhan Saravanan, Caito Samuel, et al. 2008. "Disruption of p21 attenuates lung inflammation induced by cigarette smoke, LPS, and fMLP in mice." American journal of respiratory cell and molecular biology 39 (1) doi:10.1165/rcmb.2007-0342OC
Yang Se-Ran, Valvo Samantha, Yao Hongwei, Kode Aruna, Rajendrasozhan Saravanan, et al. 2008. "IKK alpha causes chromatin modification on pro-inflammatory genes by cigarette smoke in mouse lung." American journal of respiratory cell and molecular biology 38 (6) doi:10.1165/rcmb.2007-0379OC
Yao Hongwei, Edirisinghe Indika, Rajendrasozhan Saravanan, Yang Se-Ran, Caito Samuel, et al. 2008. "Cigarette smoke-mediated inflammatory and oxidative responses are strain-dependent in mice." American journal of physiology. Lung cellular and molecular physiology 294 (6) doi:10.1152/ajplung.00439.2007
Yao Hongwei, Edirisinghe Indika, Yang Se-Ran, Rajendrasozhan Saravanan, Kode Aruna, et al. 2008. "Genetic ablation of NADPH oxidase enhances susceptibility to cigarette smoke-induced lung inflammation and emphysema in mice." The American journal of pathology 172 (5) doi:10.2353/ajpath.2008.070765
Rajendrasozhan Saravanan, Yang Se-Ran, Kinnula Vuokko L, Rahman Irfan 2008. "SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 177 (8) doi:10.1164/rccm.200708-1269OC
Rajendrasozhan Saravanan, Yang Se-Ran, Edirisinghe Indika, Yao Hongwei, Adenuga David, Rahman Irfan 2008. "Deacetylases and NF-kappaB in redox regulation of cigarette smoke-induced lung inflammation: epigenetics in pathogenesis of COPD." Antioxidants & redox signaling 10 (4) doi:10.1089/ars.2007.1938
Ryan Elizabeth P, Bushnell Timothy P, Friedman Alan E, Rahman Irfan, Phipps Richard P 2008. "Cyclooxygenase-2 independent effects of cyclooxygenase-2 inhibitors on oxidative stress and intracellular glutathione content in normal and malignant human B-cells." Cancer immunology, immunotherapy : CII 57 (3) doi:10.1007/s00262-007-0374-4
Kode Aruna, Rajendrasozhan Saravanan, Caito Samuel, Yang Se-Ran, Megson Ian L, Rahman Irfan 2008. "Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells." American journal of physiology. Lung cellular and molecular physiology 294 (3) doi:10.1152/ajplung.00361.2007
Caito Samuel, Yang Se-Ran, Kode Aruna, Edirisinghe Indika, Rajendrasozhan Saravanan, et al. 2008. "Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, PPARgamma agonists, differentially regulate cigarette smoke-mediated pro-inflammatory cytokine release in monocytes/macrophages." Antioxidants & redox signaling 10 (2) doi:10.1089/ars.2007.1889
Yao Hongwei, de Boer Willem I, Rahman Irfan 2008. "Targeting lung inflammation: novel therapies for the treatment of COPD." Current respiratory medicine reviews 4 (1) doi:10.2174/157339808783497873
Louhelainen Noora, Myllärniemi Marjukka, Rahman Irfan, Kinnula Vuokko L 2008. "Airway biomarkers of the oxidant burden in asthma and chronic obstructive pulmonary disease: current and future perspectives." International journal of chronic obstructive pulmonary disease 3 (4) doi:

2007

Stevenson Christopher S, Docx Cerys, Webster Ruth, Battram Cliff, Hynx Debra, et al. 2007. "Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation." American journal of physiology. Lung cellular and molecular physiology 293 (5) doi:10.1152/ajplung.00105.2007
Aghai Zubair H, Kode Aruna, Saslow Judy G, Nakhla Tarek, Farhath Sabeena, et al. 2007. "Azithromycin suppresses activation of nuclear factor-kappa B and synthesis of pro-inflammatory cytokines in tracheal aspirate cells from premature infants." Pediatric research 62 (4) doi:10.1203/PDR.0b013e318142582d
Yang Se-Ran, Wright Jessica, Bauter Mark, Seweryniak Kathryn, Kode Aruna, Rahman Irfan 2007. "Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging." American journal of physiology. Lung cellular and molecular physiology 292 (2) doi:10.1152/ajplung.00308.2006
de Boer Willem I, Yao Hongwei, Rahman Irfan 2007. "Future therapeutic treatment of COPD: struggle between oxidants and cytokines." International journal of chronic obstructive pulmonary disease 2 (3) doi:

2006

Morrison Douglas, Rahman Irfan, MacNee William 2006. "Permeability, inflammation and oxidant status in airspace epithelium exposed to ozone." Respiratory medicine 100 (12) doi:10.1016/j.rmed.2005.10.005
Rahman Irfan, Biswas Saibal K, Kirkham Paul A 2006. "Regulation of inflammation and redox signaling by dietary polyphenols." Biochemical pharmacology 72 (11) doi:10.1016/j.bcp.2006.07.004
Kirkham Paul, Rahman Irfan 2006. "Oxidative stress in asthma and COPD: antioxidants as a therapeutic strategy." Pharmacology & therapeutics 111 (2) doi:10.1016/j.pharmthera.2005.10.015
Baglole Carolyn J, Bushinsky Seth M, Garcia Tatiana M, Kode Aruna, Rahman Irfan, et al. 2006. "Differential induction of apoptosis by cigarette smoke extract in primary human lung fibroblast strains: implications for emphysema." American journal of physiology. Lung cellular and molecular physiology 291 (1) doi:10.1152/ajplung.00306.2005
Yang Se-Ran, Chida Asiya S, Bauter Mark R, Shafiq Nusrat, Seweryniak Kathryn, et al. 2006. "Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages." American journal of physiology. Lung cellular and molecular physiology 291 (1) doi:10.1152/ajplung.00241.2005
Rahman Irfan, Kilty Iain 2006. "Antioxidant therapeutic targets in COPD." Current drug targets 7 (6) doi:
Aghai Zubair H, Kumar Sanjay, Farhath Sabeena, Kumar Mary Ann, Saslow Judy, et al. 2006. "Dexamethasone suppresses expression of Nuclear Factor-kappaB in the cells of tracheobronchial lavage fluid in premature neonates with respiratory distress." Pediatric research 59 (6) doi:10.1203/01.pdr.0000219120.92049.b3
Marwick John A, Stevenson Christopher S, Giddings June, MacNee William, Butler Keith, et al. 2006. "Cigarette smoke disrupts VEGF165-VEGFR-2 receptor signaling complex in rat lungs and patients with COPD: morphological impact of VEGFR-2 inhibition." American journal of physiology. Lung cellular and molecular physiology 290 (5) doi:10.1152/ajplung.00116.2005
Rahman Irfan, Biswas Saibal K, Kode Aruna 2006. "Oxidant and antioxidant balance in the airways and airway diseases." European journal of pharmacology 533 (1-3) doi:10.1016/j.ejphar.2005.12.087
Biswas Saibal, Chida Asiya Seema, Rahman Irfan 2006. "Redox modifications of protein-thiols: emerging roles in cell signaling." Biochemical pharmacology 71 (5) doi:10.1016/j.bcp.2005.10.044
Rahman Irfan 2006. "Antioxidant therapies in COPD." International journal of chronic obstructive pulmonary disease 1 (1) doi:
Rahman Irfan, Kode Aruna, Biswas Saibal K 2006. "Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method." Nature protocols 1 (6) doi:10.1038/nprot.2006.378
Kode Aruna, Yang Se-Ran, Rahman Irfan 2006. "Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells." Respiratory research 7 doi:10.1186/1465-9921-7-132
Rahman Irfan, Yang Se-Ran, Biswas Saibal K 2006. "Current concepts of redox signaling in the lungs." Antioxidants & redox signaling 8 (3-4) doi:10.1089/ars.2006.8.681

2005

Biswas Saibal K, Newby David E, Rahman Irfan, Megson Ian L 2005. "Depressed glutathione synthesis precedes oxidative stress and atherogenesis in Apo-E(-/-) mice." Biochemical and biophysical research communications 338 (3) doi:10.1016/j.bbrc.2005.10.098
Rahman Irfan 2005. "Regulation of glutathione in inflammation and chronic lung diseases." Mutation research 579 (1-2) doi:10.1016/j.mrfmmm.2005.02.025
Bhattacharya Kunal, Dopp Elke, Kakkar Poonam, Jaffery Farhat N, Schiffmann Dietmar, et al. 2005. "Biomarkers in risk assessment of asbestos exposure." Mutation research 579 (1-2) doi:10.1016/j.mrfmmm.2005.02.022
Echazarreta Andrés L, Rahman Irfan, Peinado Victor, Barberà Joan Albert, Roca Josep, et al. 2005. "Lack of systemic oxidative stress during PAF challenge in mild asthma." Respiratory medicine 99 (5) doi:10.1016/j.rmed.2004.10.013
Biswas Saibal K, McClure Danny, Jimenez Luis A, Megson Ian L, Rahman Irfan 2005. "Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity." Antioxidants & redox signaling 7 (1-2) doi:10.1089/ars.2005.7.32
Rahman Irfan, Biswas Saibal K, Jimenez Luis A, Torres Martine, Forman H J 2005. "Glutathione, stress responses, and redox signaling in lung inflammation." Antioxidants & redox signaling 7 (1-2) doi:10.1089/ars.2005.7.42
Rahman Irfan 2005. "The role of oxidative stress in the pathogenesis of COPD: implications for therapy." Treatments in respiratory medicine 4 (3) doi:
Luppi Fabrizio, Aarbiou Jamil, van Wetering Sandra, Rahman Irfan, de Boer Willem I, et al. 2005. "Effects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: role of glutathione." Respiratory research 6 doi:10.1186/1465-9921-6-140
Rahman Irfan 2005. "Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: cellular and molecular mechanisms." Cell biochemistry and biophysics 43 (1) doi:10.1385/CBB:43:1:167

2004

Moodie Fiona M, Marwick John A, Anderson Charlotte S, Szulakowski Patryk, Biswas Saibal K, et al. 2004. "Oxidative stress and cigarette smoke alter chromatin remodeling but differentially regulate NF-kappaB activation and proinflammatory cytokine release in alveolar epithelial cells." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 18 (15) doi:10.1096/fj.04-1506fje
Marwick John A, Kirkham Paul A, Stevenson Christopher S, Danahay Henry, Giddings June, et al. 2004. "Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs." American journal of respiratory cell and molecular biology 31 (6) doi:10.1165/rcmb.2004-0006OC
Lim So-Young, Jang Jung-Hee, Na Hye-Kyung, Lu Shelly C, Rahman Irfan, Surh Young-Joon 2004. "15-Deoxy-Delta12,14-prostaglandin J(2) protects against nitrosative PC12 cell death through up-regulation of intracellular glutathione synthesis." The Journal of biological chemistry 279 (44) doi:10.1074/jbc.M406555200
Rahman Irfan, Marwick John, Kirkham Paul 2004. "Redox modulation of chromatin remodeling: impact on histone acetylation and deacetylation, NF-kappaB and pro-inflammatory gene expression." Biochemical pharmacology 68 (6) doi:10.1016/j.bcp.2004.05.042
Antonicelli Frank, Brown David, Parmentier Maryline, Drost Ellen M, Hirani Nik, et al. 2004. "Regulation of LPS-mediated inflammation in vivo and in vitro by the thiol antioxidant Nacystelyn." American journal of physiology. Lung cellular and molecular physiology 286 (6) doi:10.1152/ajplung.00329.2003
Maqbool Abrar, Lintner Rebecca, Bokhari Aqiba, Habib Tariq, Rahman Irfan, Rao Babar K 2004. "Anorectal melanoma--3 case reports and a review of the literature." Cutis; cutaneous medicine for the practitioner 73 (6) doi:
Kirkham Paul A, Spooner Gillian, Rahman Irfan, Rossi Adriano G 2004. "Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products." Biochemical and biophysical research communications 318 (1) doi:10.1016/j.bbrc.2004.04.003
Rahman Irfan, Biswas Saibal K 2004. "Non-invasive biomarkers of oxidative stress: reproducibility and methodological issues." Redox report : communications in free radical research 9 (3) doi:10.1179/135100004225005219

2003

Rahman Irfan, Kelly Frank 2003. "Biomarkers in breath condensate: a promising new non-invasive technique in free radical research." Free radical research 37 (12) doi:
Wickenden Julie A, Clarke Murray C H, Rossi Adriano G, Rahman Irfan, Faux Stephen P, et al. 2003. "Cigarette smoke prevents apoptosis through inhibition of caspase activation and induces necrosis." American journal of respiratory cell and molecular biology 29 (5) doi:10.1165/rcmb.2002-0235OC
Donaldson Ken, Stone Vicki, Borm Paul J A, Jimenez Luis A, Gilmour Peter S, et al. 2003. "Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10)." Free radical biology & medicine 34 (11) doi:
Rahman Irfan, Gilmour Peter S, Jimenez Luis A, Biswas Saibal K, Antonicelli Frank, Aruoma Okezie I 2003. "Ergothioneine inhibits oxidative stress- and TNF-alpha-induced NF-kappa B activation and interleukin-8 release in alveolar epithelial cells." Biochemical and biophysical research communications 302 (4) doi:
Gilmour Peter S, Rahman Irfan, Donaldson Kenneth, MacNee William 2003. "Histone acetylation regulates epithelial IL-8 release mediated by oxidative stress from environmental particles." American journal of physiology. Lung cellular and molecular physiology 284 (3) doi:10.1152/ajplung.00277.2002
Rahman Irfan 2003. "Oxidative stress, chromatin remodeling and gene transcription in inflammation and chronic lung diseases." Journal of biochemistry and molecular biology 36 (1) doi:

2002

Marwick John A, Kirkham Paul, Gilmour Peter S, Donaldson Kenneth, MacNEE William, Rahman Irfan 2002. "Cigarette smoke-induced oxidative stress and TGF-beta1 increase p21waf1/cip1 expression in alveolar epithelial cells." Annals of the New York Academy of Sciences 973 doi:
Deiana Monica, Dessi M Assunta, Ke Bin, Liang Yun-Fei, Higa Teruo, et al. 2002. "The antioxidant cocktail effective microorganism X (EM-X) inhibits oxidant-induced interleukin-8 release and the peroxidation of phospholipids in vitro." Biochemical and biophysical research communications 296 (5) doi:
Rahman Irfan 2002. "Oxidative stress, transcription factors and chromatin remodelling in lung inflammation." Biochemical pharmacology 64 (5-6) doi:
Rahman Irfan 2002. "Oxidative stress and gene transcription in asthma and chronic obstructive pulmonary disease: antioxidant therapeutic targets." Current drug targets. Inflammation and allergy 1 (3) doi:
Rahman Irfan, van Schadewijk Annemarie A M, Crowther Ann J L, Hiemstra Pieter S, Stolk Jan, et al. 2002. "4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 166 (4) doi:10.1164/rccm.2110101
Kim Hui Jung, Liu Xiangde, Wang Hangjun, Kohyama Tadashi, Kobayashi Tetsu, et al. 2002. "Glutathione prevents inhibition of fibroblast-mediated collagen gel contraction by cigarette smoke." American journal of physiology. Lung cellular and molecular physiology 283 (2) doi:10.1152/ajplung.00059.2002
Jardine Hazel, MacNee William, Donaldson Kenneth, Rahman Irfan 2002. "Molecular mechanism of transforming growth factor (TGF)-beta1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1." The Journal of biological chemistry 277 (24) doi:10.1074/jbc.M112145200
Antonicelli Frank, Parmentier Maryline, Drost Ellen M, Hirani Nik, Rahman Irfan, et al. 2002. "Nacystelyn inhibits oxidant-mediated interleukin-8 expression and NF-kappaB nuclear binding in alveolar epithelial cells." Free radical biology & medicine 32 (6) doi:
Coe Jonathan P, Rahman Irfan, Sphyris Nathalie, Clarke Alan R, Harrison David J 2002. "Glutathione and p53 independently mediate responses against oxidative stress in ES cells." Free radical biology & medicine 32 (2) doi:
Rahman Irfan, Gilmour Peter S, Jimenez Luis Albert, MacNee William 2002. "Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation." Molecular and cellular biochemistry 234-235 (1-2) doi: