Mullan M

Top coauthors of Mullan M

Crawford F (46 papers)

Town T (25 papers)

Duara R (16 papers)

Paris D (14 papers)

Tan J (13 papers)

List of Mullan M publications

2011

Kennelly S P, Abdullah L, Paris D, Parish J, Mathura V, et al. 2011. "Demonstration of safety in Alzheimer's patients for intervention with an anti-hypertensive drug Nilvadipine: results from a 6-week open label study." International journal of geriatric psychiatry 26 (10) doi:10.1002/gps.2638

2010

Ferguson S, Mouzon B, Kayihan G, Wood M, Poon F, et al. 2010. "Apolipoprotein E genotype and oxidative stress response to traumatic brain injury." Neuroscience 168 (3) doi:10.1016/j.neuroscience.2010.01.031

2009

Crawford F, Wood M, Ferguson S, Mathura V, Gupta P, et al. 2009. "Apolipoprotein E-genotype dependent hippocampal and cortical responses to traumatic brain injury." Neuroscience 159 (4) doi:10.1016/j.neuroscience.2009.01.033

2002

Townsend K P, Obregon D, Quadros A, Patel N, Volmar Ch, et al. 2002. "Proinflammatory and vasoactive effects of Abeta in the cerebrovasculature." Annals of the New York Academy of Sciences 977 doi:
Ait-Ghezala G, Abdullah L, Crescentini R, Crawford F, Town T, et al. 2002. "Confirmation of association between D10S583 and Alzheimer's disease in a case--control sample." Neuroscience letters 325 (2) doi:
Schinka J A, Town T, Abdullah L, Crawford F C, Ordorica P I, et al. 2002. "A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and other substances." Molecular psychiatry 7 (2) doi:10.1038/sj.mp.4000951

2001

Russ C, Powell J F, Zhao J, Baker M, Hutton M, et al. 2001. "The microtubule associated protein Tau gene and Alzheimer's disease--an association study and meta-analysis." Neuroscience letters 314 (1-2) doi:
Town T, Tan J, Sansone N, Obregon D, Klein T, Mullan M 2001. "Characterization of murine immunoglobulin G antibodies against human amyloid-beta1-42." Neuroscience letters 307 (2) doi:
Town T, Tan J, Mullan M 2001. "CD40 signaling and Alzheimer's disease pathogenesis." Neurochemistry international 39 (5-6) doi:

2000

Town T, Schinka J, Tan J, Mullan M 2000. "The opioid receptor system and alcoholism: a genetic perspective." European journal of pharmacology 410 (2-3) doi:
Tan J, Town T, Mullan M 2000. "CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway." The Journal of biological chemistry 275 (47) doi:10.1074/jbc.M002006200
Tan J, Town T, Mori T, Wu Y, Saxe M, et al. 2000. "CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase." The Journal of neuroscience : the official journal of the Society for Neuroscience 20 (20) doi:
Paris D, Town T, Humphrey J, Yokota K, Mullan M 2000. "Cholesterol modulates vascular reactivity to endothelin-1 by stimulating a pro-inflammatory pathway." Biochemical and biophysical research communications 274 (2) doi:10.1006/bbrc.2000.3174
Tandon A, Rogaeva E, Mullan M, St George-Hyslop P H 2000. "Molecular genetics of Alzheimer's disease: the role of beta-amyloid and the presenilins." Current opinion in neurology 13 (4) doi:
Small B J, Graves A B, McEvoy C L, Crawford F C, Mullan M, Mortimer J A 2000. "Is APOE--epsilon4 a risk factor for cognitive impairment in normal aging?" Neurology 54 (11) doi:
Kuo Y M, Crawford F, Mullan M, Kokjohn T A, Emmerling M R, et al. 2000. "Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease." Molecular medicine (Cambridge, Mass.) 6 (5) doi:
Paris D, Town T, Parker T, Humphrey J, Mullan M 2000. "A beta vasoactivity: an inflammatory reaction." Annals of the New York Academy of Sciences 903 doi:
Suo Z, Su G, Placzek A, Kundtz A, Humphrey J, et al. 2000. "A beta vasoactivity in vivo." Annals of the New York Academy of Sciences 903 doi:
Crawford F, Abdullah L, Schinka J, Suo Z, Gold M, et al. 2000. "Gender-specific association of the angiotensin converting enzyme gene with Alzheimer's disease." Neuroscience letters 280 (3) doi:
Paris D, Town T, Mullan M 2000. "Novel strategies for opposing murine microglial activation." Neuroscience letters 278 (1-2) doi:
Sevush S, Peruyera G, Crawford F, Mullan M 2000. "Apolipoprotein-E epsilon 4 allele frequency and conferred risk for Cuban Americans with Alzheimer's disease." The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 8 (3) doi:
Paris D, Town T, Mori T, Parker T A, Humphrey J, Mullan M 2000. "Soluble beta-amyloid peptides mediate vasoactivity via activation of a pro-inflammatory pathway." Neurobiology of aging 21 (2) doi:

1999

Tan J, Town T, Paris D, Mori T, Suo Z, et al. 1999. "Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation." Science (New York, N.Y.) 286 (5448) doi:
Tan J, Town T, Saxe M, Paris D, Wu Y, Mullan M 1999. "Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent TNF-alpha production that is opposed by TGF-beta 1 and IL-10." Journal of immunology (Baltimore, Md. : 1950) 163 (12) doi:
Town T, Abdullah L, Crawford F, Schinka J, Ordorica P I, et al. 1999. "Association of a functional mu-opioid receptor allele (+118A) with alcohol dependency." American journal of medical genetics 88 (5) doi:
Town T, Paris D, Parker T A, Kundtz A, Tan J, et al. 1999. "Alzheimers disease is not associated with the hypertension genetic risk factors PLA(2) or G protein beta3, either independently or interactively with apolipoprotein E." American journal of medical genetics 88 (5) doi:
Tan J, Town T, Suo Z, Wu Y, Song S, et al. 1999. "Induction of CD40 on human endothelial cells by Alzheimer's beta-amyloid peptides." Brain research bulletin 50 (2) doi:
Tan J, Town T, Placzek A, Kundtz A, Yu H, Mullan M 1999. "Bcl-X(L) inhibits apoptosis and necrosis produced by Alzheimer's beta-amyloid1-40 peptide in PC12 cells." Neuroscience letters 272 (1) doi:
Crawford F, Town T, Freeman M, Schinka J, Gold M, et al. 1999. "The alpha-2 macroglobulin gene is not associated with Alzheimer's disease in a case-control sample." Neuroscience letters 270 (3) doi:
Arendash G W, Su G C, Crawford F C, Bjugstad K B, Mullan M 1999. "Intravascular beta-amyloid infusion increases blood pressure: implications for a vasoactive role of beta-amyloid in the pathogenesis of Alzheimer's disease." Neuroscience letters 268 (1) doi:
Tan J, Town T, Paris D, Placzek A, Parker T, et al. 1999. "Activation of microglial cells by the CD40 pathway: relevance to multiple sclerosis." Journal of neuroimmunology 97 (1-2) doi:
Crawford F, Freeman M, Town T, Fallin D, Gold M, et al. 1999. "No genetic association between polymorphisms in the Tau gene and Alzheimer's disease in clinic or population based samples." Neuroscience letters 266 (3) doi:
Paris D, Town T, Parker T A, Tan J, Humphrey J, et al. 1999. "Inhibition of Alzheimer's beta-amyloid induced vasoactivity and proinflammatory response in microglia by a cGMP-dependent mechanism." Experimental neurology 157 (1) doi:10.1006/exnr.1999.7055
Harwood D G, Barker W W, Ownby R L, Mullan M, Duara R 1999. "Factors associated with depressive symptoms in non-demented community-dwelling elderly." International journal of geriatric psychiatry 14 (5) doi:
Su G C, Arendash G W, Kalaria R N, Bjugstad K B, Mullan M 1999. "Intravascular infusions of soluble beta-amyloid compromise the blood-brain barrier, activate CNS glial cells and induce peripheral hemorrhage." Brain research 818 (1) doi:
Harwood D G, Barker W W, Loewenstein D A, Ownby R L, St George-Hyslop P, et al. 1999. "A cross-ethnic analysis of risk factors for AD in white Hispanics and white non-Hispanics." Neurology 52 (3) doi:

1998

Suo Z, Humphrey J, Kundtz A, Sethi F, Placzek A, et al. 1998. "Soluble Alzheimers beta-amyloid constricts the cerebral vasculature in vivo." Neuroscience letters 257 (2) doi:
Paris D, Town T, Parker T A, Humphrey J, Mullan M 1998. "Isoform-specific vasoconstriction induced by apolipoprotein E and modulation of this effect by Alzheimer's beta-amyloid peptide." Neuroscience letters 256 (2) doi:
Crawford F, Soto C, Suo Z, Fang C, Parker T, et al. 1998. "Alzheimer's beta-amyloid vasoactivity: identification of a novel beta-amyloid conformational intermediate." FEBS letters 436 (3) doi:
Suo Z, Tan J, Placzek A, Crawford F, Fang C, Mullan M 1998. "Alzheimer's beta-amyloid peptides induce inflammatory cascade in human vascular cells: the roles of cytokines and CD40." Brain research 807 (1-2) doi:
Town T, Paris D, Fallin D, Duara R, Barker W, et al. 1998. "The -491A/T apolipoprotein E promoter polymorphism association with Alzheimer's disease: independent risk and linkage disequilibrium with the known APOE polymorphism." Neuroscience letters 252 (2) doi:
Paris D, Parker T A, Town T, Suo Z, Fang C, et al. 1998. "Role of peroxynitrite in the vasoactive and cytotoxic effects of Alzheimer's beta-amyloid1-40 peptide." Experimental neurology 152 (1) doi:10.1006/exnr.1998.6828
Crawford F, Fallin D, Suo Z, Abdullah L, Gold M, et al. 1998. "The butyrylcholinesterase gene is neither independently nor synergistically associated with late-onset AD in clinic- and community-based populations." Neuroscience letters 249 (2-3) doi:
Crawford F, Suo Z, Fang C, Mullan M 1998. "Characteristics of the in vitro vasoactivity of beta-amyloid peptides." Experimental neurology 150 (1) doi:10.1006/exnr.1997.6743

1997

Crawford F, Suo Z, Fang C, Sawar A, Su G, et al. 1997. "The vasoactivity of A beta peptides." Annals of the New York Academy of Sciences 826 doi:
Fallin D, Kundtz A, Town T, Gauntlett A C, Duara R, et al. 1997. "No association between the low density lipoprotein receptor-related protein (LRP) gene and late-onset Alzheimer's disease in a community-based sample." Neuroscience letters 233 (2-3) doi:
Cai X, Fallin D, Stanton J, Scibelli P, Duara R, et al. 1997. "APOE is linked to Alzheimer's disease in a large pedigree." American journal of medical genetics 74 (4) doi:
Suo Z, Fang C, Crawford F, Mullan M 1997. "Superoxide free radical and intracellular calcium mediate A beta(1-42) induced endothelial toxicity." Brain research 762 (1-2) doi:
Fallin D, Reading S, Schinka J, Hoyne J, Scibelli P, et al. 1997. "No interaction between the APOE and the alpha-1-antichymotrypsin genes on risk for Alzheimer's disease." American journal of medical genetics 74 (2) doi:
Cai X, Stanton J, Fallin D, Hoyne J, Duara R, et al. 1997. "No association between the intronic presenilin-1 polymorphism and Alzheimer's disease in clinic and population-based samples." American journal of medical genetics 74 (2) doi:
Fallin D, Gauntlett A C, Scibelli P, Cai X, Duara R, et al. 1997. "No association between the very low density lipoprotein receptor gene and late-onset Alzheimer's disease nor interaction with the apolipoprotein E gene in population-based and clinic samples." Genetic epidemiology 14 (3) doi:10.1002/(SICI)1098-2272(1997)14:3<299::AID-GEPI7>3.0.CO;2-0

1996

Mullan M, Scibelli P, Duara R, Fallin D, Gold M, et al. 1996. "Familial and population-based studies of apolipoprotein E and Alzheimer's disease." Annals of the New York Academy of Sciences 802 doi:
Crawford F, Hoyne J, Cai X, Osborne A, Poston D, et al. 1996. "Dopamine DRD2/Cys311 is not associated with chronic schizophrenia." American journal of medical genetics 67 (5) doi:10.1002/(SICI)1096-8628(19960920)67:5<483::AID-AJMG8>3.0.CO;2-L
Thomas T, Thomas G, McLendon C, Sutton T, Mullan M 1996. "beta-Amyloid-mediated vasoactivity and vascular endothelial damage." Nature 380 (6570) doi:10.1038/380168a0

1995

Poduslo S E, Riggs D, Schwankhaus J, Osborne A, Crawford F, Mullan M 1995. "Association of apolipoprotein E but not B with Alzheimer's disease." Human genetics 96 (5) doi:
Crawford F, Hoyne J, Diaz P, Osborne A, Dorotheo J, et al. 1995. "Occurrence of the Cys311 DRD2 variant in a pedigree multiply affected with panic disorder." American journal of medical genetics 60 (4) doi:10.1002/ajmg.1320600414
Bennett C, Crawford F, Osborne A, Diaz P, Hoyne J, et al. 1995. "Evidence that the APOE locus influences rate of disease progression in late onset familial Alzheimer's Disease but is not causative." American journal of medical genetics 60 (1) doi:10.1002/ajmg.1320600102
Mullan M, Bennett C, Figueredo C, Hughes D, Mant R, et al. 1995. "Clinical features of early onset, familial Alzheimer's disease linked to chromosome 14." American journal of medical genetics 60 (1) doi:10.1002/ajmg.1320600109

1994

Mullan M, Crawford F 1994. "The molecular genetics of Alzheimer's disease." Molecular neurobiology 9 (1-3) doi:10.1007/BF02816100
Westbrook C A, Le Beau M M, Neuman W L, Keinanen M, Yamaoka L H, et al. 1994. "Physical and genetic map of 5q31: use of fluorescence in situ hybridization data to identify errors in the CEPH database. Centre d'Etude de Polymorphisme Humain." Cytogenetics and cell genetics 67 (2) doi:
Mullan M, Crawford F, Buchanan J 1994. "Technical feasibility of genetic testing for Alzheimer's disease." Alzheimer disease and associated disorders 8 (2) doi:

1993

Mullan M, Houlden H, Crawford F, Kennedy A, Rogues P, Rossor M 1993. "Age of onset in familial early onset Alzheimer's disease correlates with genetic aetiology." American journal of medical genetics 48 (3) doi:10.1002/ajmg.1320480303
Mullan M, Crawford F 1993. "Genetic and molecular advances in Alzheimer's disease." Trends in neurosciences 16 (10) doi:
Houlden H, Crawford F, Rossor M, Mullan M 1993. "Screening for the APP codon 670/671 mutations in Alzheimer's disease." Neuroscience letters 154 (1-2) doi:
Kennedy A M, Newman S, McCaddon A, Ball J, Roques P, et al. 1993. "Familial Alzheimer's disease. A pedigree with a mis-sense mutation in the amyloid precursor protein gene (amyloid precursor protein 717 valine-->glycine)." Brain : a journal of neurology 116 ( Pt 2) doi:
Brown J, Gydesen S, Sorensen S A, Brun A, Smith S, et al. 1993. "Genetic characterization of a familial non-specific dementia originating in Jutland, Denmark." Journal of the neurological sciences 114 (2) doi:
Mullan M, Tsuji S, Miki T, Katsuya T, Naruse S, et al. 1993. "Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val-->Ile mutation in the amyloid precursor protein gene." Neurobiology of aging 14 (5) doi:

1992

Mullan M, Houlden H, Windelspecht M, Fidani L, Lombardi C, et al. 1992. "A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal to the alpha 1-antichymotrypsin gene." Nature genetics 2 (4) doi:10.1038/ng1292-340
Mullan M, Crawford F, Axelman K, Houlden H, Lilius L, et al. 1992. "A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid." Nature genetics 1 (5) doi:10.1038/ng0892-345
Collinge J, Brown J, Hardy J, Mullan M, Rossor M N, et al. 1992. "Inherited prion disease with 144 base pair gene insertion. 2. Clinical and pathological features." Brain : a journal of neurology 115 ( Pt 3) doi:
Fidani L, Rooke K, Chartier-Harlin M C, Hughes D, Tanzi R, et al. 1992. "Screening for mutations in the open reading frame and promoter of the beta-amyloid precursor protein gene in familial Alzheimer's disease: identification of a further family with APP717 Val-->Ile." Human molecular genetics 1 (3) doi:
Thom B, Brown C, Drummond C, Edwards G, Mullan M, Taylor C 1992. "Engaging patients with alcohol problems in treatment: the first consultation." British journal of addiction 87 (4) doi:
Thom B, Brown C, Drummond C, Edwards G, Mullan M 1992. "The use of services for alcohol problems: general practitioner and specialist alcohol clinic." British journal of addiction 87 (4) doi:
Lantos P L, Luthert P J, Hanger D, Anderton B H, Mullan M, Rossor M 1992. "Familial Alzheimer's disease with the amyloid precursor protein position 717 mutation and sporadic Alzheimer's disease have the same cytoskeletal pathology." Neuroscience letters 137 (2) doi:

1991

Crawford F, Hardy J, Mullan M, Goate A, Hughes D, et al. 1991. "Sequencing of exons 16 and 17 of the beta-amyloid precursor protein gene in 14 families with early onset Alzheimer's disease fails to reveal mutations in the beta-amyloid sequence." Neuroscience letters 133 (1) doi:
Chartier-Harlin M C, Crawford F, Hamandi K, Mullan M, Goate A, et al. 1991. "Screening for the beta-amyloid precursor protein mutation (APP717: Val----Ile) in extended pedigrees with early onset Alzheimer's disease." Neuroscience letters 129 (1) doi:
Goate A, Chartier-Harlin M C, Mullan M, Brown J, Crawford F, et al. 1991. "Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease." Nature 349 (6311) doi:10.1038/349704a0
Brown J, Smith S, Brun A, Collinge J, Gydesen S, et al. 1991. "Genetic characterization of a novel familial dementia." Annals of the New York Academy of Sciences 640 doi:

1990

St George-Hyslop P H, Haines J L, Farrer L A, Polinsky R, Van Broeckhoven C, et al. 1990. "Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder." Nature 347 (6289) doi:10.1038/347194a0

1989

Mullan M 1989. "Alcoholism and the 'new genetics'." British journal of addiction 84 (12) doi: