Morishita Ryuichi

Top coauthors of Morishita Ryuichi

Nakagami Hironori (93 papers)

Ogihara Toshio (89 papers)

Kaneda Yasufumi (81 papers)

Taniyama Yoshiaki (54 papers)

Rakugi Hiromi (53 papers)

List of Morishita Ryuichi publications

2017

Sanada Fumihiro, Muratsu Jun, Otsu Rei, Shimizu Hideo, Koibuchi Nobutaka, et al. 2017. "Local Production of Activated Factor X in Atherosclerotic Plaque Induced Vascular Smooth Muscle Cell Senescence." Scientific reports 7 (1) doi:10.1038/s41598-017-17508-6
Miyake Takashi, Miyake Tetsuo, Shimizu Hideo, Morishita Ryuichi 2017. "Inhibition of Aneurysm Progression by Direct Renin Inhibition in a Rabbit Model." Hypertension (Dallas, Tex. : 1979) 70 (6) doi:10.1161/HYPERTENSIONAHA.117.09815
Chen Chang-I, Yeh Jong-Shiuan, Tsao Nai-Wen, Lin Fen-Yen, Shih Chun-Ming, et al. 2017. "Association between renin-angiotensin-aldosterone system blockade and future osteoporotic fracture risk in hypertensive population: A population-based cohort study in Taiwan." Medicine 96 (46) doi:10.1097/MD.0000000000008331
Pang Zhengda, Kushiyama Akifumi, Sun Jiao, Kikuchi Takako, Yamazaki Hiroki, et al. 2017. "Glial fibrillary acidic protein (GFAP) is a novel biomarker for the prediction of autoimmune diabetes." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 31 (9) doi:10.1096/fj.201700110R
Wakayama Kouji, Shimamura Munehisa, Suzuki Jun-Ichi, Watanabe Ryo, Koriyama Hiroshi, et al. 2017. "Angiotensin II Peptide Vaccine Protects Ischemic Brain Through Reducing Oxidative Stress." Stroke 48 (5) doi:10.1161/STROKEAHA.116.016269
Minhas Gillipsie, Prabhakar Sudesh, Morishita Ryuichi, Shimamura Munehisa, Bansal Reema, Anand Akshay 2017. "Transplantation of lineage-negative stem cells in pterygopalatine artery ligation induced retinal ischemia-reperfusion injury in mice." Molecular and cellular biochemistry 429 (1-2) doi:10.1007/s11010-017-2941-0
Muratsu Jun, Iwabayashi Masaaki, Sanada Fumihiro, Taniyama Yoshiaki, Otsu Rei, et al. 2017. "Hepatocyte Growth Factor Prevented High-Fat Diet-Induced Obesity and Improved Insulin Resistance in Mice." Scientific reports 7 (1) doi:10.1038/s41598-017-00199-4
Watanabe Ryo, Suzuki Jun-Ichi, Wakayama Kouji, Maejima Yasuhiro, Shimamura Munehisa, et al. 2017. "A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction." Scientific reports 7 doi:10.1038/srep43920
Pang Zhengda, Higuchi Masayoshi, Koriyama Hiroshi, Yoshida Shota, Kurinami Hitomi, et al. 2017. "Evaluating the potential of the GFAP-KLH immune-tolerizing vaccine for type 1 diabetes in mice." FEBS letters 591 (1) doi:10.1002/1873-3468.12511
Nakaya Yutaka, Fukuda Daiju, Oyamada Takashi, Ogawa Kazuo, Harada Nagakatsu, et al. 2017. "A novel lipoprotein (a) lowering drug, D-47, decreases neointima thickening after vascular injury." The journal of medical investigation : JMI 64 (1.2) doi:10.2152/jmi.64.64

2016

Kurinami Hitomi, Shimamura Munehisa, Nakagami Hironori, Shimizu Hideo, Koriyama Hiroshi, et al. 2016. "A Novel Therapeutic Peptide as a Partial Agonist of RANKL in Ischemic Stroke." Scientific reports 6 doi:10.1038/srep38062
Sanada Fumihiro, Taniyama Yoshiaki, Muratsu Jun, Otsu Rei, Iwabayashi Masaaki, et al. 2016. "Activated Factor X Induces Endothelial Cell Senescence Through IGFBP-5." Scientific reports 6 doi:10.1038/srep35580
Nakama Takahito, Yoshida Shigeo, Ishikawa Keijiro, Kobayashi Yoshiyuki, Abe Takaya, et al. 2016. "Different roles played by periostin splice variants in retinal neovascularization." Experimental eye research doi:10.1016/j.exer.2016.10.012
Morishita Ryuichi 2016. "SY 14-4 VACCINE THERAPY FOR RESISTANT HYPERTENSION: IS IT A DYING ISSUE?" Journal of hypertension 34 Suppl 1 - ISH 2016 Abstract Book doi:10.1097/01.hjh.0000500954.56466.87
Morishita Ryuichi 2016. "SY 14-4 VACCINE THERAPY FOR RESISTANT HYPERTENSION: IS IT A DYING ISSUE?" Journal of hypertension 34 Suppl 1 - ISH 2016 Abstract Book doi:10.1097/01.hjh.0000500954.56466.87
Sotobayashi Daisuke, Kawahata Hirohisa, Anada Natsuki, Ogihara Toshio, Morishita Ryuichi, Aoki Motokuni 2016. "Therapeutic Effect of Intra-Articular Injection of Ribbon-Type Decoy Oligonucleotides for Hypoxia Inducible Factor-1 on Joint Contracture in an Immobilized Knee Animal Model." The journal of gene medicine doi:10.1002/jgm.2891
Zempo Hirofumi, Suzuki Jun-Ichi, Ogawa Masahito, Watanabe Ryo, Fujiu Katsuhito, et al. 2016. "Influence of periostin-positive cell-specific Klf5 deletion on aortic thickening in DOCA-salt hypertensive mice." Hypertension research : official journal of the Japanese Society of Hypertension doi:10.1038/hr.2016.65
Suzuki Jun-Ichi, Shimamura Munehisa, Suda Hiroyuki, Wakayama Kouji, Kumagai Hidetoshi, et al. 2016. "Current therapies and investigational drugs for peripheral arterial disease." Hypertension research : official journal of the Japanese Society of Hypertension 39 (4) doi:10.1038/hr.2015.134
Sanada Fumihiro, Kanbara Yasuhiro, Taniyama Yoshiaki, Otsu Rei, Carracedo Miguel, et al. 2016. "Induction of Angiogenesis by a Type III Phosphodiesterase Inhibitor, Cilostazol, Through Activation of Peroxisome Proliferator-Activated Receptor-γ and cAMP Pathways in Vascular Cells." Arteriosclerosis, thrombosis, and vascular biology 36 (3) doi:10.1161/ATVBAHA.115.307011
Taniyama Yoshiaki, Katsuragi Naruto, Sanada Fumihiro, Azuma Junya, Iekushi Kazuma, et al. 2016. "Selective Blockade of Periostin Exon 17 Preserves Cardiac Performance in Acute Myocardial Infarction." Hypertension 67 (2) doi:10.1161/HYPERTENSIONAHA.115.06265
Kawakami Ryo, Nakagami Hironori, Noma Takahisa, Ohmori Koji, Kohno Masakazu, Morishita Ryuichi 2016. "RANKL system in vascular and valve calcification with aging." Inflammation and regeneration 36 doi:10.1186/s41232-016-0016-3

2015

Minhas Gillipsie, Morishita Ryuichi, Shimamura Munehisa, Bansal Reema, Anand Akshay 2015. "Modeling transient retinal ischemia in mouse by ligation of pterygopalatine artery." Annals of neurosciences 22 (4) doi:10.5214/ans.0972.7531.220406
Aoki Motokuni, Kawahata Hirohisa, Sotobayashi Daisuke, Yu Hisahiro, Moriguchi Atsushi, et al. 2015. "Effect of angiotensin II receptor blocker, olmesartan, on turnover of bone metabolism in bedridden elderly hypertensive women with disuse syndrome." Geriatrics & gerontology international 15 (8) doi:10.1111/ggi.12406
Koriyama Hiroshi, Nakagami Hironori, Nakagami Futoshi, Osako Mariana Kiomy, Kyutoku Mariko, et al. 2015. "Long-Term Reduction of High Blood Pressure by Angiotensin II DNA Vaccine in Spontaneously Hypertensive Rats." Hypertension 66 (1) doi:10.1161/HYPERTENSIONAHA.114.04534
Kawahata Hirohisa, Sotobayashi Daisuke, Aoki Motokuni, Shimizu Hideo, Nakagami Hironori, et al. 2015. "Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse." Hypertension research : official journal of the Japanese Society of Hypertension 38 (6) doi:10.1038/hr.2015.18
Nakagami Hironori, Morishita Ryuichi 2015. "Development of DNA vaccines as an anti-hypertensive therapy or for anti-angiogenesis." Expert opinion on biological therapy 15 (3) doi:10.1517/14712598.2015.1014791
Sanada Fumihiro, Taniyama Yoshiaki, Kanbara Yasuhiro, Otsu Rei, Ikeda-Iwabu Yuka, et al. 2015. "Gene therapy in peripheral artery disease." Expert opinion on biological therapy 15 (3) doi:10.1517/14712598.2015.1007039
Morishita Ryuichi, Nakagami Hironori 2015. "Teneligliptin : expectations for its pleiotropic action." Expert opinion on pharmacotherapy 16 (3) doi:10.1517/14656566.2015.1000301
Sato Naoyuki, Morishita Ryuichi 2015. "The roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer disease." Frontiers in aging neuroscience 7 doi:10.3389/fnagi.2015.00199
Lin Feng-Yen, Tsao Nai-Wen, Shih Chun-Ming, Lin Yi-Wen, Yeh Jong-Shiua, et al. 2015. "The biphasic effects of oxidized-low density lipoprotein on the vasculogenic function of endothelial progenitor cells." PloS one 10 (5) doi:10.1371/journal.pone.0123971
Rodriguez-Araujo Gerardo, Nakagami Hironori, Takami Yoichi, Katsuya Tomohiro, Akasaka Hiroshi, et al. 2015. "Low alpha-synuclein levels in the blood are associated with insulin resistance." Scientific reports 5 doi:10.1038/srep12081

2014

Miyake Takashi, Ihara Shinya, Miyake Tetsuo, Tsukada Yusuke, Watanabe Hajime, et al. 2014. "Prevention of neointimal formation after angioplasty using nuclear factor-κB decoy oligodeoxynucleotide-coated balloon catheter in rabbit model." Circulation. Cardiovascular interventions 7 (6) doi:10.1161/CIRCINTERVENTIONS.114.001522
Suda Hiroyuki, Murakami Akihiko, Kaga Toshihiro, Tomioka Hideki, Morishita Ryuichi 2014. "Beperminogene perplasmid for the treatment of critical limb ischemia." Expert review of cardiovascular therapy 12 (10) doi:10.1586/14779072.2014.955850
Shimamura Munehisa, Nakagami Hironori, Taniyama Yoshiaki, Morishita Ryuichi 2014. "Gene therapy for peripheral arterial disease." Expert opinion on biological therapy 14 (8) doi:10.1517/14712598.2014.912272
Shimizu Hideo, Nakagami Hironori, Morishita Ryuichi 2014. "[Bone metabolism and cardiovascular function update. Cross link of hypertension, bone loss and vascular calcification - common back grounds in renin angiotensin system with anti-aging aspect -]." Clinical calcium 24 (7) doi:CliCa140710211030
Nakagami Hironori, Pang Zhengda, Shimosato Takashi, Moritani Toshinori, Kurinami Hitomi, et al. 2014. "The dipeptidyl peptidase-4 inhibitor teneligliptin improved endothelial dysfunction and insulin resistance in the SHR/NDmcr-cp rat model of metabolic syndrome." Hypertension research : official journal of the Japanese Society of Hypertension 37 (7) doi:10.1038/hr.2014.53
Shimamura Munehisa, Nakagami Hironori, Osako Mariana K, Kurinami Hitomi, Koriyama Hiroshi, et al. 2014. "OPG/RANKL/RANK axis is a critical inflammatory signaling system in ischemic brain in mice." Proceedings of the National Academy of Sciences of the United States of America 111 (22) doi:10.1073/pnas.1400544111
Shimamura Munehisa, Taniyama Yoshiaki, Nakagami Hironori, Katsuragi Naruto, Wakayama Kouji, et al. 2014. "Long-term expression of periostin during the chronic stage of ischemic stroke in mice." Hypertension research : official journal of the Japanese Society of Hypertension 37 (6) doi:10.1038/hr.2014.36
Kusunoki Hiroshi, Taniyama Yoshiaki, Otsu Rei, Rakugi Hiromi, Morishita Ryuichi 2014. "Anti-inflammatory effects of hepatocyte growth factor on the vicious cycle of macrophages and adipocytes." Hypertension research : official journal of the Japanese Society of Hypertension 37 (6) doi:10.1038/hr.2014.41
Sanada Fumihiro, Taniyama Yoshiaki, Azuma Junya, Yuka Ikeda-Iwabe, Kanbara Yasuhiro, et al. 2014. "Therapeutic Angiogenesis by Gene Therapy for Critical Limb Ischemia: Choice of Biological Agent." Immunology, endocrine & metabolic agents in medicinal chemistry 14 (1) doi:10.2174/1871522213999131231105139
Pang Zhengda, Nakagami Hironori, Osako Mariana K, Koriyama Hiroshi, Nakagami Futoshi, et al. 2014. "Therapeutic vaccine against DPP4 improves glucose metabolism in mice." Proceedings of the National Academy of Sciences of the United States of America 111 (13) doi:10.1073/pnas.1322009111
Nakagami Hironori, Koriyama Hiroshi, Morishita Ryuichi 2014. "Peptide Vaccines for Hypertension and Diabetes Mellitus." Vaccines 2 (4) doi:10.3390/vaccines2040832
Nakagami Hironori, Koriyama Hiroshi, Morishita Ryuichi 2014. "Therapeutic vaccines for hypertension and dyslipidemia." International heart journal 55 (2) doi:
Takeda Shuko, Sato Naoyuki, Morishita Ryuichi 2014. "Systemic inflammation, blood-brain barrier vulnerability and cognitive/non-cognitive symptoms in Alzheimer disease: relevance to pathogenesis and therapy." Frontiers in aging neuroscience 6 doi:10.3389/fnagi.2014.00171
Sanada Sumihiro, Taniyama Yoshiaki, Azuma Junya, Yuka Ikeda-Iwabe, Iwabayashi Masaaki, et al. 2014. "Endothelial progenitor cells in clinical settings." Journal of stem cells 9 (2) doi:jsc.2014.9.2.117
Tomioka Hideki, Nakagami Hironori, Tenma Akiko, Saito Yoshimi, Kaga Toshihiro, et al. 2014. "Novel anti-microbial peptide SR-0379 accelerates wound healing via the PI3 kinase/Akt/mTOR pathway." PloS one 9 (3) doi:10.1371/journal.pone.0092597
Shinohara Mitsuru, Sato Naoyuki, Shimamura Munehisa, Kurinami Hitomi, Hamasaki Toshimitsu, et al. 2014. "Possible modification of Alzheimer's disease by statins in midlife: interactions with genetic and non-genetic risk factors." Frontiers in aging neuroscience 6 doi:10.3389/fnagi.2014.00071
Sato Naoyuki, Morishita Ryuichi 2014. "Brain alterations and clinical symptoms of dementia in diabetes: aβ/tau-dependent and independent mechanisms." Frontiers in endocrinology 5 doi:10.3389/fendo.2014.00143

2013

Takeda Shuko, Sato Naoyuki, Ikimura Kazuko, Nishino Hirohito, Rakugi Hiromi, Morishita Ryuichi 2013. "Increased blood-brain barrier vulnerability to systemic inflammation in an Alzheimer disease mouse model." Neurobiology of aging 34 (8) doi:10.1016/j.neurobiolaging.2013.02.010
Kurinami Hitomi, Shimamura Munehisa, Sato Naoyuki, Nakagami Hironori, Morishita Ryuichi 2013. "Do Angiotensin receptor blockers protect against Alzheimer's disease?" Drugs & aging 30 (6) doi:10.1007/s40266-013-0071-2
Osako Mariana Kiomy, Nakagami Hironori, Shimamura Munehisa, Koriyama Hiroshi, Nakagami Futoshi, et al. 2013. "Cross-Talk of Receptor Activator of Nuclear Factor-κB Ligand Signaling With Renin-Angiotensin System in Vascular Calcification." Arteriosclerosis, thrombosis, and vascular biology 33 (6) doi:10.1161/ATVBAHA.112.301099
Shimamura Munehisa, Nakagami Hironori, Sata Masataka, Takaoka Minoru, Azuma Junya, et al. 2013. "Unique remodeling processes after vascular injury in intracranial arteries: analysis using a novel mouse model." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism doi:10.1038/jcbfm.2013.62
Kyutoku Mariko, Nakagami Hironori, Koriyama Hiroshi, Nakagami Futoshi, Shimamura Munehisa, et al. 2013. "Inhibition of neointima formation through DNA vaccination for apolipoprotein(a): a new therapeutic strategy for lipoprotein(a)." Scientific reports 3 doi:10.1038/srep01600
Kusunoki Hiroshi, Taniyama Yoshiaki, Rakugi Hiromi, Morishita Ryuichi 2013. "Cardiac and renal protective effects of irbesartan via peroxisome proliferator-activated receptorγ-hepatocyte growth factor pathway independent of angiotensin II Type 1a receptor blockade in mouse model of salt-sensitive hypertension." Journal of the American Heart Association 2 (2) doi:10.1161/JAHA.113.000103
Nakagami Hironori, Morishita Ryuichi 2013. "[Hypertension and osteoporosis]." Clinical calcium 23 (4) doi:CliCa1304497503
Rodriguez-Araujo Gerardo, Nakagami Hironori, Hayashi Hiroki, Mori Masaki, Shiuchi Tetsuya, et al. 2013. "Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway." Cellular and molecular life sciences : CMLS 70 (6) doi:10.1007/s00018-012-1198-8
Katsuya Tomohiro, Morishita Ryuichi 2013. "Gene Polymorphism of Angiotensin II Type 1 and Type 2 Receptors." Current pharmaceutical design 19 (17) doi:
Nakagami Hironori, Osako Mariana Kiomy, Morishita Ryuichi 2013. "Potential Effect of Angiotensin II Receptor Blockade in Adipose Tissue and Bone." Current pharmaceutical design 19 (17) doi:
Nakagami Futoshi, Koriyama Hiroshi, Nakagami Hironori, Osako Mariana Kiomy, Shimamura Munehisa, et al. 2013. "Decrease in blood pressure and regression of cardiovascular complications by angiotensin II vaccine in mice." PloS one 8 (3) doi:10.1371/journal.pone.0060493
Shimamura Munehisa, Nakagami Hironori, Koriyama Hiroshi, Morishita Ryuichi 2013. "Gene therapy and cell-based therapies for therapeutic angiogenesis in peripheral artery disease." BioMed research international 2013 doi:10.1155/2013/186215
Chatterjee Amarnath, Kusunoki Hiroshi, Taniyama Yoshiaki, Rakugi Hiromi, Morishita Ryuichi 2013. "Improvement of metabolic syndrome by irbesartan via the PPARγ/HGF pathway in apolipoprotein E knockout mice." Biomedical reports 1 (1) doi:10.3892/br.2012.28
Saito Yukihiro, Nakagami Hironori, Kaneda Yasufumi, Morishita Ryuichi 2013. "Lymphedema and therapeutic lymphangiogenesis." BioMed research international 2013 doi:10.1155/2013/804675
Sato Naoyuki, Morishita Ryuichi 2013. "Roles of vascular and metabolic components in cognitive dysfunction of Alzheimer disease: short- and long-term modification by non-genetic risk factors." Frontiers in aging neuroscience 5 doi:10.3389/fnagi.2013.00064
Kyutoku Mariko, Nakagami Hironori, Koriyama Hiroshi, Tomioka Hideki, Nakagami Futoshi, et al. 2013. "Development of novel DNA vaccine for VEGF in murine cancer model." Scientific reports 3 doi:10.1038/srep03380

2012

Huang Chun-Yao, Shih Chun-Ming, Tsao Nai-Wen, Lin Yi-Wen, Huang Po-Hsun, et al. 2012. "Dipeptidyl peptidase-4 inhibitor improves neovascularization by increasing circulating endothelial progenitor cells." British journal of pharmacology 167 (7) doi:10.1111/j.1476-5381.2012.02102.x
Ozaki Kazunari, Makino Hirofumi, Aoki Motokuni, Miyake Takashi, Yasumasa Natsuki, et al. 2012. "Therapeutic effect of ribbon-type nuclear factor-κB decoy oligonucleotides in a rat model of inflammatory bowel disease." Current gene therapy 12 (6) doi:
Shimizu Kazutaka, Taniyama Yoshiaki, Sanada Fumihiro, Azuma Junya, Iwabayashi Masaaki, et al. 2012. "Hepatocyte growth factor inhibits lipopolysaccharide-induced oxidative stress via epithelial growth factor receptor degradation." Arteriosclerosis, thrombosis, and vascular biology 32 (11) doi:10.1161/ATVBAHA.112.300041
Makino Hirofumi, Aoki Motokuni, Hashiya Naotaka, Yamasaki Keita, Azuma Junya, et al. 2012. "Long-term follow-up evaluation of results from clinical trial using hepatocyte growth factor gene to treat severe peripheral arterial disease." Arteriosclerosis, thrombosis, and vascular biology 32 (10) doi:10.1161/ATVBAHA.111.244632
Huang Chun-Yao, Lin Feng-Yen, Shih Chun-Ming, Au Heng-Kien, Chang Yu-Jia, et al. 2012. "Moderate to high concentrations of high-density lipoprotein from healthy subjects paradoxically impair human endothelial progenitor cells and related angiogenesis by activating Rho-associated kinase pathways." Arteriosclerosis, thrombosis, and vascular biology 32 (10) doi:10.1161/ATVBAHA.112.248617
Shimizu Hideo, Nakagami Hironori, Morishita Ryuichi 2012. "[Activation of osteoclasts by RAAS and strategy of target therapy on bone metabolic diseases]." Nihon rinsho. Japanese journal of clinical medicine 70 (9) doi:
Kaga Toshihiro, Kawano Hirokazu, Sakaguchi Makoto, Nakazawa Takahiro, Taniyama Yoshiaki, Morishita Ryuichi 2012. "Hepatocyte growth factor stimulated angiogenesis without inflammation: differential actions between hepatocyte growth factor, vascular endothelial growth factor and basic fibroblast growth factor." Vascular pharmacology 57 (1) doi:10.1016/j.vph.2012.02.002
Nakagami Hironori, Nishikawa Tomoyuki, Tamura Nao, Maeda Akito, Hibino Hajime, et al. 2012. "Modification of a novel angiogenic peptide, AG30, for the development of novel therapeutic agents." Journal of cellular and molecular medicine 16 (7) doi:10.1111/j.1582-4934.2011.01406.x
Iwabayashi Masaaki, Taniyama Yoshiaki, Sanada Fumihiro, Azuma Junya, Iekushi Kazuma, et al. 2012. "Inhibition of Lp(a)-induced functional impairment of endothelial cells and endothelial progenitor cells by hepatocyte growth factor." Biochemical and biophysical research communications 423 (1) doi:10.1016/j.bbrc.2012.05.086
Hayashi Hiroki, Nakagami Hironori, Takeichi Makiko, Shimamura Munehisa, Koibuchi Nobutaka, et al. 2012. "HIG1, a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 26 (6) doi:10.1096/fj.11-196063
Aoki Tomohiro, Kataoka Hiroharu, Nishimura Masaki, Ishibashi Ryota, Morishita Ryuichi, Miyamoto Susumu 2012. "Regression of intracranial aneurysms by simultaneous inhibition of nuclear factor-κB and Ets with chimeric decoy oligodeoxynucleotide treatment." Neurosurgery 70 (6) doi:10.1227/NEU.0b013e318246a390
Okayama Keita, Azuma Junya, Dosaka Norio, Iekushi Kazuma, Sanada Fumihiro, et al. 2012. "Hepatocyte growth factor reduces cardiac fibrosis by inhibiting endothelial-mesenchymal transition." Hypertension 59 (5) doi:10.1161/HYPERTENSIONAHA.111.183905
Shimamura Munehisa, Taniyama Yoshiaki, Katsuragi Naruto, Koibuchi Nobutaka, Kyutoku Mariko, et al. 2012. "Role of central nervous system periostin in cerebral ischemia." Stroke; a journal of cerebral circulation 43 (4) doi:10.1161/STROKEAHA.111.636662
Morishita Ryuichi, Itakura Hiroshige, Nakaya Noriaki, Yoshida Masayuki, Odawara Masato, et al. 2012. "Risk factors for cardiovascular events in Japanese patients treated with fluvastatin from the long-term event monitoring (LEM) study." Current vascular pharmacology 10 (2) doi:
Kusunoki Hiroshi, Taniyama Yoshiaki, Azuma Junya, Iekushi Kazuma, Sanada Fumihiro, et al. 2012. "Telmisartan exerts renoprotective actions via peroxisome proliferator-activated receptor-γ/hepatocyte growth factor pathway independent of angiotensin II type 1 receptor blockade." Hypertension 59 (2) doi:10.1161/HYPERTENSIONAHA.111.176263
Iwabayashi Masaaki, Taniyama Yoshiaki, Sanada Fumihiro, Azuma Junya, Iekushi Kazuma, et al. 2012. "Role of serotonin in angiogenesis: induction of angiogenesis by sarpogrelate via endothelial 5-HT1B/Akt/eNOS pathway in diabetic mice." Atherosclerosis 220 (2) doi:10.1016/j.atherosclerosis.2011.10.042
Sato Naoyuki, Shinohara Mitsuru, Rakugi Hiromi, Morishita Ryuichi 2012. "Dual effects of statins on Aβ metabolism: upregulation of the degradation of APP-CTF and Aβ clearance." Neuro-degenerative diseases 10 (1-4) doi:10.1159/000334534
Nakagami Hironori, Shimamura Munehisa, Miyake Takashi, Shimosato Takashi, Minobe Noriko, et al. 2012. "Nifedipine prevents hepatic fibrosis in a non-alcoholic steatohepatitis model induced by an L-methionine-and choline-deficient diet." Molecular medicine reports 5 (1) doi:10.3892/mmr.2011.594
Shimizu Hideo, Nakagami Hironori, Yasumasa Natsuki, Mariana Osako Kiomy, Kyutoku Mariko, et al. 2012. "Cilnidipine, but not amlodipine, ameliorates osteoporosis in ovariectomized hypertensive rats through inhibition of the N-type calcium channel." Hypertension research : official journal of the Japanese Society of Hypertension 35 (1) doi:10.1038/hr.2011.143
Osako Mariana Kiomy, Nakagami Hironori, Morishita Ryuichi 2012. "Modification of decoy oligodeoxynucleotides to achieve the stability and therapeutic efficacy." Current topics in medicinal chemistry 12 (15) doi:
Suzuki Jun-Ichi, Isobe Mitsuaki, Morishita Ryuichi, Nagai Ryozo 2012. "Applications of nucleic acid drugs for organ transplantation." Current topics in medicinal chemistry 12 (15) doi:
Miyake Takashi, Nakagami Hironori, Morishita Ryuichi 2012. "Nucleic acid drugs for preventing restenosis after coronary revascularization." Current topics in medicinal chemistry 12 (15) doi:
Shimamura Munehisa, Sato Naoyuki, Nakagami Hironori, Taniyama Yoshiaki, Morishita Ryuichi 2012. "Development of nucleic acid drugs for neurological disorders." Current topics in medicinal chemistry 12 (15) doi:
Sato Naoyuki, Okochi Masayasu, Shinohara Mitsuru, Thinakaran Gopal, Takeda Shuko, et al. 2012. "Differential regulation of amyloid precursor protein/presenilin 1 interaction during Aβ40/42 [corrected] production detected using fusion constructs." PloS one 7 (11) doi:10.1371/journal.pone.0048551
Minhas Gillipsie, Morishita Ryuichi, Anand Akshay 2012. "Preclinical models to investigate retinal ischemia: advances and drawbacks." Frontiers in neurology 3 doi:10.3389/fneur.2012.00075
Takeda Shuko, Sato Naoyuki, Uchio-Yamada Kozue, Yu Hisahiro, Moriguchi Atsushi, et al. 2012. "Oral glucose loading modulates plasma β-amyloid level in alzheimer's disease patients: potential diagnostic method for Alzheimer's disease." Dementia and geriatric cognitive disorders 34 (1) doi:10.1159/000338704
Taniyama Yoshiaki, Azuma Junya, Kunugiza Yasuo, Iekushi Kazuma, Rakugi Hiromi, Morishita Ryuichi 2012. "Therapeutic option of plasmid-DNA based gene transfer." Current topics in medicinal chemistry 12 (15) doi:

2011

Taniyama Yoshiaki, Azuma Junya, Rakugi Hiromi, Morishita Ryuichi 2011. "Plasmid DNA-based gene transfer with ultrasound and microbubbles." Current gene therapy 11 (6) doi:
Shimamura Munehisa, Sato Naoyuki, Morishita Ryuichi 2011. "Experimental and clinical application of plasmid DNA in the field of central nervous diseases." Current gene therapy 11 (6) doi:
Saito Yukihiro, Nakagami Hironori, Azuma Nobuyoshi, Hirata Satoshi, Sanada Fumihiro, et al. 2011. "Critical roles of cold shock domain protein A as an endogenous angiogenesis inhibitor in skeletal muscle." Antioxidants & redox signaling 15 (8) doi:10.1089/ars.2010.3714
Suzuki Jun-Ichi, Ogawa Masahito, Watanabe Ryo, Morishita Ryuichi, Hirata Yasunobu, et al. 2011. "Autoimmune giant cell myocarditis: clinical characteristics, experimental models and future treatments." Expert opinion on therapeutic targets 15 (10) doi:10.1517/14728222.2011.601294
Shimamura Munehisa, Nakagami Hironori, Shimosato Takashi, Moritani Toshinori, Nakagami Futoshi, et al. 2011. "Irbesartan improves endothelial dysfunction, abnormal lipid profile, proteinuria and liver dysfunction in Zucker diabetic fatty rats independent of glucose and insulin levels." Experimental and therapeutic medicine 2 (5) doi:10.3892/etm.2011.307
Iekushi Kazuma, Taniyama Yoshiaki, Kusunoki Hiroshi, Azuma Junya, Sanada Fumihiro, et al. 2011. "Hepatocyte growth factor attenuates transforming growth factor-β-angiotensin II crosstalk through inhibition of the PTEN/Akt pathway." Hypertension 58 (2) doi:10.1161/HYPERTENSIONAHA.111.173013
Kyutoku Mariko, Taniyama Yoshiaki, Katsuragi Naruto, Shimizu Hideo, Kunugiza Yasuo, et al. 2011. "Role of periostin in cancer progression and metastasis: inhibition of breast cancer progression and metastasis by anti-periostin antibody in a murine model." International journal of molecular medicine 28 (2) doi:10.3892/ijmm.2011.712
Sato Naoyuki, Takeda Shuko, Uchio-Yamada Kozue, Ueda Hironori, Fujisawa Tomomi, et al. 2011. "Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus: a missing link to therapeutic potential." Current aging science 4 (2) doi:
Takeda Shuko, Sato Naoyuki, Rakugi Hiromi, Morishita Ryuichi 2011. "Molecular mechanisms linking diabetes mellitus and Alzheimer disease: beta-amyloid peptide, insulin signaling, and neuronal function." Molecular bioSystems 7 (6) doi:10.1039/c0mb00302f
Nakagami Hironori, Morishita Ryuichi 2011. "[Hypertension, CKD and bone metabolism]." Clinical calcium 21 (5) doi:CliCa1105685689
Shioyama Wataru, Nakaoka Yoshikazu, Higuchi Kaori, Minami Takashi, Taniyama Yoshiaki, et al. 2011. "Docking protein Gab1 is an essential component of postnatal angiogenesis after ischemia via HGF/c-met signaling." Circulation research 108 (6) doi:10.1161/CIRCRESAHA.110.232223
Morishita Ryuichi, Makino Hirofumi, Aoki Motokuni, Hashiya Naotaka, Yamasaki Keita, et al. 2011. "Phase I/IIa clinical trial of therapeutic angiogenesis using hepatocyte growth factor gene transfer to treat critical limb ischemia." Arteriosclerosis, thrombosis, and vascular biology 31 (3) doi:10.1161/ATVBAHA.110.219550
Nakagami Hironori, Morishita Ryuichi 2011. "Obesity and gastrointestinal hormones-dual effect of angiotensin II receptor blockade and a partial agonist of PPAR-γ." Current vascular pharmacology 9 (2) doi:
Ohno Kazuki, Amano Yasushi, Kakuta Hirotoshi, Niimi Tatsuya, Takakura Shoji, et al. 2011. "Unique "delta lock" structure of telmisartan is involved in its strongest binding affinity to angiotensin II type 1 receptor." Biochemical and biophysical research communications 404 (1) doi:10.1016/j.bbrc.2010.11.139
Miyake Takashi, Aoki Motokuni, Osako Mariana K, Shimamura Munehisa, Nakagami Hironori, Morishita Ryuichi 2011. "Systemic administration of ribbon-type decoy oligodeoxynucleotide against nuclear factor κB and ets prevents abdominal aortic aneurysm in rat model." Molecular therapy : the journal of the American Society of Gene Therapy 19 (1) doi:10.1038/mt.2010.208
Nakagami Hironori, Osako Mariana K, Morishita Ryuichi 2011. "New concept of vascular calcification and metabolism." Current vascular pharmacology 9 (1) doi:
Tahara Kohei, Samura Sota, Tsuji Kaori, Yamamoto Hiromitsu, Tsukada Yusuke, et al. 2011. "Oral nuclear factor-κB decoy oligonucleotides delivery system with chitosan modified poly(D,L-lactide-co-glycolide) nanospheres for inflammatory bowel disease." Biomaterials 32 (3) doi:10.1016/j.biomaterials.2010.09.034

2010

Iekushi Kazuma, Taniyama Yoshiaki, Azuma Junya, Sanada Fumihiro, Kusunoki Hiroshi, et al. 2010. "Hepatocyte growth factor attenuates renal fibrosis through TGF-β1 suppression by apoptosis of myofibroblasts." Journal of hypertension 28 (12) doi:10.1097/HJH.0b013e32833e4149
Koriyama Hiroshi, Nakagami Hironori, Katsuya Tomohiro, Sugimoto Ken, Yamashita Hidetoshi, et al. 2010. "Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population." Journal of atherosclerosis and thrombosis 17 (10) doi:
Nakagami Hironori, Kiomy Osako Mariana, Nakagami Futoshi, Shimosato Takashi, Minobe Noriko, et al. 2010. "Prevention and regression of non-alcoholic steatohepatitis (NASH) in a rat model by metabosartan, telmisartan." International journal of molecular medicine 26 (4) doi:
Takeda Shuko, Sato Naoyuki, Rakugi Hiromi, Morishita Ryuichi 2010. "Plasma beta-amyloid as potential biomarker of Alzheimer disease: possibility of diagnostic tool for Alzheimer disease." Molecular bioSystems 6 (10) doi:10.1039/c003148h
Osako Mariana Kiomy, Nakagami Hironori, Koibuchi Nobutaka, Shimizu Hideo, Nakagami Futoshi, et al. 2010. "Estrogen inhibits vascular calcification via vascular RANKL system: common mechanism of osteoporosis and vascular calcification." Circulation research 107 (4) doi:10.1161/CIRCRESAHA.110.216846
Shinohara Mitsuru, Sato Naoyuki, Kurinami Hitomi, Takeuchi Daisuke, Takeda Shuko, et al. 2010. "Reduction of brain beta-amyloid (Abeta) by fluvastatin, a hydroxymethylglutaryl-CoA reductase inhibitor, through increase in degradation of amyloid precursor protein C-terminal fragments (APP-CTFs) and Abeta clearance." The Journal of biological chemistry 285 (29) doi:10.1074/jbc.M110.102277
Nakagami Futoshi, Nakagami Hironori, Osako Mariana Kiomy, Iwabayashi Masaaki, Taniyama Yoshiaki, et al. 2010. "Estrogen attenuates vascular remodeling in Lp(a) transgenic mice." Atherosclerosis 211 (1) doi:10.1016/j.atherosclerosis.2010.01.016
Morimoto Daiki, Tomita Tetsuya, Kuroda Shoko, Higuchi Chikahisa, Kato Shinichi, et al. 2010. "Inorganic polyphosphate differentiates human mesenchymal stem cells into osteoblastic cells." Journal of bone and mineral metabolism 28 (4) doi:10.1007/s00774-010-0157-4
Taniyama Yoshiaki, Sanada Fumihiro, Morishita Ryuichi 2010. "[Therapeutic angiogenesis for diabetes mellitus related ischemic disease]." Nihon rinsho. Japanese journal of clinical medicine 68 (5) doi:
Koriyama Hiroshi, Nakagami Hironori, Katsuya Tomohiro, Akasaka Hiroshi, Saitoh Shigeyuki, et al. 2010. "Variation in OSBPL10 is associated with dyslipidemia." Hypertension research : official journal of the Japanese Society of Hypertension 33 (5) doi:10.1038/hr.2010.28
Takeda Shuko, Sato Naoyuki, Uchio-Yamada Kozue, Sawada Kyoko, Kunieda Takanori, et al. 2010. "Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes." Proceedings of the National Academy of Sciences of the United States of America 107 (15) doi:10.1073/pnas.1000645107
Ohshima Satoru, Fujimoto Shinichiro, Petrov Artiom, Nakagami Hironori, Haider Nezam, et al. 2010. "Effect of an antimicrobial agent on atherosclerotic plaques: assessment of metalloproteinase activity by molecular imaging." Journal of the American College of Cardiology 55 (12) doi:10.1016/j.jacc.2009.11.056
Suzuki Jun-ichi, Ogawa Masahito, Takayama Kiyoshi, Taniyama Yoshiaki, Morishita Ryuichi, et al. 2010. "Ultrasound-microbubble-mediated intercellular adhesion molecule-1 small interfering ribonucleic acid transfection attenuates neointimal formation after arterial injury in mice." Journal of the American College of Cardiology 55 (9) doi:10.1016/j.jacc.2009.09.054
Suzuki Jun-ichi, Isobe Mitsuaki, Morishita Ryuichi, Nagai Ryozo 2010. "Characteristics of chronic rejection in heart transplantation: important elements of pathogenesis and future treatments." Circulation journal : official journal of the Japanese Circulation Society 74 (2) doi:
Sugimoto Ken, Katsuya Tomohiro, Kamide Kei, Fujisawa Tomomi, Shimaoka Izumi, et al. 2010. "Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study." International journal of hypertension 2010 doi:10.4061/2010/196307

2009

Takeda Shuko, Sato Naoyuki, Takeuchi Daisuke, Kurinami Hitomi, Shinohara Mitsuru, et al. 2009. "Angiotensin receptor blocker prevented beta-amyloid-induced cognitive impairment associated with recovery of neurovascular coupling." Hypertension 54 (6) doi:10.1161/HYPERTENSIONAHA.109.138586
Kim Min-Seok, Lee Choon-Soo, Hur Jin, Cho Hyun-Jai, Jun Soo-In, et al. 2009. "Priming with angiopoietin-1 augments the vasculogenic potential of the peripheral blood stem cells mobilized with granulocyte colony-stimulating factor through a novel Tie2/Ets-1 pathway." Circulation 120 (22) doi:10.1161/CIRCULATIONAHA.109.856815
Hayashi Shin-ichiro, Sato Naoyuki, Yamamoto Akitsugu, Ikegame Yuka, Nakashima Shigeru, et al. 2009. "Alzheimer disease-associated peptide, amyloid beta40, inhibits vascular regeneration with induction of endothelial autophagy." Arteriosclerosis, thrombosis, and vascular biology 29 (11) doi:10.1161/ATVBAHA.109.188516
Sanada Fumihiro, Taniyama Yoshiaki, Iekushi Kazuma, Azuma Junya, Okayama Keita, et al. 2009. "Negative action of hepatocyte growth factor/c-Met system on angiotensin II signaling via ligand-dependent epithelial growth factor receptor degradation mechanism in vascular smooth muscle cells." Circulation research 105 (7) doi:10.1161/CIRCRESAHA.109.202713
Shimizu Hideo, Nakagami Hironori, Morita Shosuke, Tsukamoto Ikuyo, Osako Mariana Kiomy, et al. 2009. "New treatment of periodontal diseases by using NF-kappaB decoy oligodeoxynucleotides via prevention of bone resorption and promotion of wound healing." Antioxidants & redox signaling 11 (9) doi:10.1089/ARS.2008.2355
Shimizu Hideo, Nakagami Hironori, Osako Mariana Kiomy, Nakagami Futoshi, Kunugiza Yasuo, et al. 2009. "Prevention of osteoporosis by angiotensin-converting enzyme inhibitor in spontaneous hypertensive rats." Hypertension research : official journal of the Japanese Society of Hypertension 32 (9) doi:10.1038/hr.2009.99
Aoki Tomohiro, Nishimura Masaki, Kataoka Hiroharu, Ishibashi Ryota, Miyake Takashi, et al. 2009. "Role of angiotensin II type 1 receptor in cerebral aneurysm formation in rats." International journal of molecular medicine 24 (3) doi:
Morishita Ryuichi, Ishii Junichi, Kusumi Yoshiaki, Yamada Shingo, Komai Norio, et al. 2009. "Association of serum oxidized lipoprotein(a) concentration with coronary artery disease: potential role of oxidized lipoprotein(a) in the vasucular wall." Journal of atherosclerosis and thrombosis 16 (4) doi:
Katsuya Tomohiro, Morishita Ryuichi, Rakugi Hiromi, Ogihrara Toshio 2009. "Genetic basis of hypertension for the development of tailored medicine." Hypertension research : official journal of the Japanese Society of Hypertension 32 (8) doi:10.1038/hr.2009.87
Miyake Takashi, Morishita Ryuichi 2009. "Pharmacological treatment of abdominal aortic aneurysm." Cardiovascular research 83 (3) doi:10.1093/cvr/cvp155
Takeda Shuko, Sato Naoyuki, Uchio-Yamada Kozue, Sawada Kyoko, Kunieda Takanori, et al. 2009. "Elevation of plasma beta-amyloid level by glucose loading in Alzheimer mouse models." Biochemical and biophysical research communications 385 (2) doi:10.1016/j.bbrc.2009.05.037
Takeda Shuko, Sato Naoyuki, Niisato Kazue, Takeuchi Daisuke, Kurinami Hitomi, et al. 2009. "Validation of Abeta1-40 administration into mouse cerebroventricles as an animal model for Alzheimer disease." Brain research 1280 doi:10.1016/j.brainres.2009.05.035
Nakagami Hironori, Morishita Ryuichi 2009. "[Hormones and osteoporosis update. Effect of angiotensin II on bone metabolism]." Clinical calcium 19 (7) doi:CliCa>09079971002
Mori Masaki, Nakagami Hironori, Koibuchi Nobutaka, Miura Koichi, Takami Yoichi, et al. 2009. "Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis." Molecular biology of the cell 20 (13) doi:10.1091/mbc.E09-01-0046
Katsuya Tomohiro, Morishita Ryuichi 2009. "[WRN gene]." Nihon rinsho. Japanese journal of clinical medicine 67 (7) doi:
Nakagami Hironori, Morishita Ryuichi 2009. "[Gene therapy for anti-aging medicine]." Nihon rinsho. Japanese journal of clinical medicine 67 (7) doi:
Hayashi Hiroki, Nakagami Hironori, Takami Yoichi, Koriyama Hiroshi, Mori Masaki, et al. 2009. "FHL-2 suppresses VEGF-induced phosphatidylinositol 3-kinase/Akt activation via interaction with sphingosine kinase-1." Arteriosclerosis, thrombosis, and vascular biology 29 (6) doi:10.1161/ATVBAHA.108.178541
Kimura Satoshi, Egashira Kensuke, Chen Ling, Nakano Kaku, Iwata Eiko, et al. 2009. "Nanoparticle-mediated delivery of nuclear factor kappaB decoy into lungs ameliorates monocrotaline-induced pulmonary arterial hypertension." Hypertension 53 (5) doi:10.1161/HYPERTENSIONAHA.108.121418
Tsukada Yusuke, Hara Kaori, Bando Yohei, Huang C C, Kousaka Yasuo, et al. 2009. "Particle size control of poly(dl-lactide-co-glycolide) nanospheres for sterile applications." International journal of pharmaceutics 370 (1-2) doi:10.1016/j.ijpharm.2008.11.019
Nakagami Hironori, Osako Mariana Kiomy, Takami Yoichi, Hanayama Rie, Koriyama Hiroshi, et al. 2009. "Vascular protective effects of ezetimibe in ApoE-deficient mice." Atherosclerosis 203 (1) doi:10.1016/j.atherosclerosis.2008.05.026
Nishikawa Tomoyuki, Nakagami Hironori, Maeda Akito, Morishita Ryuichi, Miyazaki Nobuhiko, et al. 2009. "Development of a novel antimicrobial peptide, AG-30, with angiogenic properties." Journal of cellular and molecular medicine 13 (3) doi:10.1111/j.1582-4934.2008.00341.x
Shiraya Suguru, Miyake Takashi, Aoki Motokuni, Yoshikazu Fujiwara, Ohgi Shigetsugu, et al. 2009. "Inhibition of development of experimental aortic abdominal aneurysm in rat model by atorvastatin through inhibition of macrophage migration." Atherosclerosis 202 (1) doi:10.1016/j.atherosclerosis.2008.03.020
Tsuchihara Toyokazu, Ogata Sho, Nemoto Koichi, Okabayashi Takatoshi, Nakanishi Kuniaki, et al. 2009. "Nonviral retrograde gene transfer of human hepatocyte growth factor improves neuropathic pain-related phenomena in rats." Molecular therapy : the journal of the American Society of Gene Therapy 17 (1) doi:10.1038/mt.2008.214
Suzuki Jun-Ichi, Tezuka Daisuke, Morishita Ryuichi, Isobe Mitsuaki 2009. "An initial case of suppressed restenosis with nuclear factor-kappa B decoy transfection after percutaneous coronary intervention." The journal of gene medicine 11 (1) doi:10.1002/jgm.1266
Sanada Fumihiro, Taniyama Yoshiaki, Azuma Junya, Iekushi Kazuma, Dosaka Norio, et al. 2009. "Hepatocyte growth factor, but not vascular endothelial growth factor, attenuates angiotensin II-induced endothelial progenitor cell senescence." Hypertension 53 (1) doi:10.1161/HYPERTENSIONAHA.108.120725
Suzuki Jun-ichi, Isobe Mitsuaki, Morishita Ryuichi, Nagai Ryozo 2009. "Tea polyphenols regulate key mediators on inflammatory cardiovascular diseases." Mediators of inflammation 2009 doi:10.1155/2009/494928
Tomita Naruya, Yamasaki Keita, Osako Mariana K, Komai Norio, Shimosato Takashi, Morishita Ryuichi 2009. "Combination therapy based on the angiotensin receptor blocker olmesartan for vascular protection in spontaneously hypertensive rats." Molecular medicine reports 2 (5) doi:10.3892/mmr_00000164
Suzuki Jun-ichi, Isobe Mitsuaki, Morishita Ryuichi, Nagai Ryozo 2009. "Nucleic acid drugs for prevention of cardiac rejection." Journal of biomedicine & biotechnology 2009 doi:10.1155/2009/916514

2008

Fujiwara Yoshikazu, Shiraya Suguru, Miyake Takashi, Yamakawa Satoshi, Aoki Motokuni, et al. 2008. "Inhibition of experimental abdominal aortic aneurysm in a rat model by the angiotensin receptor blocker valsartan." International journal of molecular medicine 22 (6) doi:
Wakayama Kouji, Shimamura Munehisa, Sata Masataka, Koibuchi Nobutaka, Sato Naoyuki, et al. 2008. "A model of cerebrovascular injury in rats." Journal of neuroscience methods 175 (2) doi:10.1016/j.jneumeth.2008.08.018
Miyake Takashi, Aoki Motokuni, Morishita Ryuichi 2008. "Inhibition of anastomotic intimal hyperplasia using a chimeric decoy strategy against NFkappaB and E2F in a rabbit model." Cardiovascular research 79 (4) doi:10.1093/cvr/cvn139
Tsubouchi Mina, Morishita Ryuichi, Tabata Yasuhiko, Matsui Shigeyuki, Kawakami Koji 2008. "Critical issues for effective collaboration between academia and industry in the field of regenerative medicine in Japan." Regenerative medicine 3 (4) doi:10.2217/17460751.3.4.497
Shimizu Hideo, Nakagami Hironori, Osako Mariana Kiomy, Hanayama Rie, Kunugiza Yasuo, et al. 2008. "Angiotensin II accelerates osteoporosis by activating osteoclasts." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 22 (7) doi:10.1096/fj.07-098954
Egashira Kensuke, Suzuki Jun-ichi, Ito Hiroshi, Aoki Motokuni, Isobe Mitsuaki, Morishita Ryuichi 2008. "Long-term follow up of initial clinical cases with NF-kappaB decoy oligodeoxynucleotide transfection at the site of coronary stenting." The journal of gene medicine 10 (7) doi:10.1002/jgm.1192
Powell Richard J, Simons Michael, Mendelsohn Farrel O, Daniel George, Henry Timothy D, et al. 2008. "Results of a double-blind, placebo-controlled study to assess the safety of intramuscular injection of hepatocyte growth factor plasmid to improve limb perfusion in patients with critical limb ischemia." Circulation 118 (1) doi:10.1161/CIRCULATIONAHA.107.727347
Kurinami Hitomi, Sato Naoyuki, Shinohara Mitsuru, Takeuchi Daisuke, Takeda Shuko, et al. 2008. "Prevention of amyloid beta-induced memory impairment by fluvastatin, associated with the decrease in amyloid beta accumulation and oxidative stress in amyloid beta injection mouse model." International journal of molecular medicine 21 (5) doi:
Nagao Kaori, Taniyama Yoshiaki, Kietzmann Thomas, Doi Takefumi, Komuro Issei, Morishita Ryuichi 2008. "HIF-1alpha signaling upstream of NKX2.5 is required for cardiac development in Xenopus." The Journal of biological chemistry 283 (17) doi:10.1074/jbc.M702563200
Azuma Haruhito, Tomita Naruya, Sakamoto Takeshi, Kiyama Satoshi, Inamoto Teruo, et al. 2008. "Marked regression of liver metastasis by combined therapy of ultrasound-mediated NF kappaB-decoy transfer and transportal injection of paclitaxel, in mouse." International journal of cancer. Journal international du cancer 122 (7) doi:10.1002/ijc.23280
Takami Yoichi, Nakagami Hironori, Morishita Ryuichi, Katsuya Tomohiro, Hayashi Hiroki, et al. 2008. "Potential role of CYLD (Cylindromatosis) as a deubiquitinating enzyme in vascular cells." The American journal of pathology 172 (3) doi:10.2353/ajpath.2008.070312
Tomita Naruya, Yamasaki Keita, Izawa Keiko, Kunugiza Yasuo, Osako Mariana K, et al. 2008. "Inhibition of experimental abdominal aortic aneurysm progression by nifedipine." International journal of molecular medicine 21 (2) doi:
Takeda Shuko, Sato Naoyuki, Ogihara Toshio, Morishita Ryuichi 2008. "The renin-angiotensin system, hypertension and cognitive dysfunction in Alzheimer's disease: new therapeutic potential." Frontiers in bioscience : a journal and virtual library 13 doi:
Nakagami Hironori, Osako Mariana Kiomy, Takami Yoichi, Hanayama Rie, Koriyama Hiroshi, et al. 2008. "Differential response of vascular hepatocyte growth factor concentration and lipid accumulation between telmisartan and losartan in ApoE-deficient mice." Molecular medicine reports 1 (5) doi:10.3892/mmr_00000008

2007

Aoki Tomohiro, Kataoka Hiroharu, Shimamura Munehisa, Nakagami Hironori, Wakayama Kouji, et al. 2007. "NF-kappaB is a key mediator of cerebral aneurysm formation." Circulation 116 (24) doi:10.1161/CIRCULATIONAHA.107.728303
Nakagami Hironori, Kikuchi Yasushi, Katsuya Tomohiro, Morishita Ryuichi, Akasaka Hiroshi, et al. 2007. "Gene polymorphism of myospryn (cardiomyopathy-associated 5) is associated with left ventricular wall thickness in patients with hypertension." Hypertension research : official journal of the Japanese Society of Hypertension 30 (12) doi:10.1291/hypres.30.1239
Nakagawa Aya, Makino Hirofumi, Aoki Motokuni, Miyake Takashi, Shiraya Suguru, et al. 2007. "Improvement of survival of skin flaps by combined gene transfer of hepatocyte growth factor and prostacyclin synthase." The journal of gene medicine 9 (12) doi:10.1002/jgm.1105
Shimamura Munehisa, Sato Naoyuki, Sata Masataka, Kurinami Hitomi, Takeuchi Daisuke, et al. 2007. "Delayed postischemic treatment with fluvastatin improved cognitive impairment after stroke in rats." Stroke; a journal of cerebral circulation 38 (12) doi:10.1161/STROKEAHA.107.485045
Miyake Takashi, Aoki Motokuni, Masaki Hisao, Kawasaki Tomio, Oishi Masako, et al. 2007. "Regression of abdominal aortic aneurysms by simultaneous inhibition of nuclear factor kappaB and ets in a rabbit model." Circulation research 101 (11) doi:10.1161/CIRCRESAHA.107.148668
Hayashi Hiroki, Nakagami Hironori, Takami Yoichi, Sato Naoyuki, Saito Yukihiro, et al. 2007. "Involvement of gamma-secretase in postnatal angiogenesis." Biochemical and biophysical research communications 363 (3) doi:10.1016/j.bbrc.2007.09.003
Taniguchi Hirokazu, Fujiwara Yoshiyuki, Doki Yuichiro, Sugita Yurika, Sohma Itsuro, et al. 2007. "Gene therapy using ets-1 transcription factor decoy for peritoneal dissemination of gastric cancer." International journal of cancer. Journal international du cancer 121 (7) doi:10.1002/ijc.22870
Takami Yoichi, Nakagami Hironori, Morishita Ryuichi, Katsuya Tomohiro, Cui Tai-Xing, et al. 2007. "Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kappaB activation." Arteriosclerosis, thrombosis, and vascular biology 27 (10) doi:10.1161/ATVBAHA.107.142505
Osako Mariana Kiomy, Tomita Naruya, Nakagami Hironori, Kunugiza Yasuo, Yoshino Masafumi, et al. 2007. "Increase in nuclease resistance and incorporation of NF-kappaB decoy oligodeoxynucleotides by modification of the 3'-terminus." The journal of gene medicine 9 (9) doi:10.1002/jgm.1077
Nakagami Hironori, Morishita Ryuichi 2007. "Recent progress in therapeutic angiogenesis." International journal of biomedical science : IJBS 3 (3) doi:
Nagao Kaori, Taniyama Yoshiaki, Koibuchi Nobutaka, Morishita Ryuichi 2007. "Constitutive over-expression of VEGF results in reduced expression of Hand-1 during cardiac development in Xenopus." Biochemical and biophysical research communications 359 (3) doi:10.1016/j.bbrc.2007.05.140
Shimamura Munehisa, Sato Naoyuki, Sata Masataka, Wakayama Kouji, Ogihara Toshio, Morishita Ryuichi 2007. "Expression of hepatocyte growth factor and c-Met after spinal cord injury in rats." Brain research 1151 doi:10.1016/j.brainres.2007.03.022
Iekushi Kazuma, Taniyama Yoshiaki, Azuma Junya, Katsuragi Naruto, Dosaka Norio, et al. 2007. "Novel mechanisms of valsartan on the treatment of acute myocardial infarction through inhibition of the antiadhesion molecule periostin." Hypertension 49 (6) doi:10.1161/HYPERTENSIONAHA.106.080994
Tomita Naruya, Yamasaki Keita, Izawa Keiko, Kunugiza Yasuo, Osako Mariana K, et al. 2007. "Improvement of organ damage by a non-depressor dose of imidapril in diabetic spontaneously hypertensive rats." International journal of molecular medicine 19 (4) doi:
Tomita Naruya, Kashihara Naoki, Morishita Ryuichi 2007. "Transcription factor decoy oligonucleotide-based therapeutic strategy for renal disease." Clinical and experimental nephrology 11 (1) doi:10.1007/s10157-007-0459-6
Wakayama Kouji, Shimamura Munehisa, Sata Masataka, Sato Naoyuki, Kawakami Koji, et al. 2007. "Quantitative measurement of neurological deficit after mild (30 min) transient middle cerebral artery occlusion in rats." Brain research 1130 (1) doi:10.1016/j.brainres.2006.10.088

2006

Ohtani Kisho, Egashira Kensuke, Nakano Kaku, Zhao Gang, Funakoshi Kouta, et al. 2006. "Stent-based local delivery of nuclear factor-kappaB decoy attenuates in-stent restenosis in hypercholesterolemic rabbits." Circulation 114 (25) doi:10.1161/CIRCULATIONAHA.105.582254
Ozaki Kazunari, Morishita Ryuichi, Ogihara Toshio 2006. "[Overview on diagnosis, treatment and therapeutic angiogenesis for arteriosclerosis obliterans]." Nihon rinsho. Japanese journal of clinical medicine 64 (11) doi:
Taniyama Yoshiaki, Morishita Ryuichi 2006. "[Development of plasmid DNA-based gene transfer]." Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 126 (11) doi:
Shiraya Suguru, Miwa Ken, Aoki Motokuni, Miyake Takashi, Oishi Masako, et al. 2006. "Hypertension accelerated experimental abdominal aortic aneurysm through upregulation of nuclear factor kappaB and Ets." Hypertension 48 (4) doi:10.1161/01.HYP.0000240266.26185.57
Saito Yukihiro, Nakagami Hironori, Morishita Ryuichi, Takami Yoichi, Kikuchi Yasushi, et al. 2006. "Transfection of human hepatocyte growth factor gene ameliorates secondary lymphedema via promotion of lymphangiogenesis." Circulation 114 (11) doi:10.1161/CIRCULATIONAHA.105.602953
Miyake Takashi, Aoki Motokuni, Shiraya Suguru, Tanemoto Kazuo, Ogihara Toshio, et al. 2006. "Inhibitory effects of NFkappaB decoy oligodeoxynucleotides on neointimal hyperplasia in a rabbit vein graft model." Journal of molecular and cellular cardiology 41 (3) doi:10.1016/j.yjmcc.2006.04.006
Tomita Tetsuya, Kunugiza Yasuo, Tomita Naruya, Takano Hiroshi, Morishita Ryuichi, et al. 2006. "E2F decoy oligodeoxynucleotide ameliorates cartilage invasion by infiltrating synovium derived from rheumatoid arthritis." International journal of molecular medicine 18 (2) doi:
Nakagami Hironori, Nakagawa Namika, Takeya Yasushi, Kashiwagi Katsunobu, Ishida Chisato, et al. 2006. "Model of vasculogenesis from embryonic stem cells for vascular research and regenerative medicine." Hypertension 48 (1) doi:10.1161/01.HYP.0000225426.12101.15
Sato Naoyuki, Okochi Masayasu, Taniyama Yoshiaki, Kurinami Hitomi, Shimamura Munehisa, et al. 2006. "Development of new screening system for Alzheimer disease, in vitro Abeta sink assay, to identify the dissociation of soluble Abeta from fibrils." Neurobiology of disease 22 (3) doi:10.1016/j.nbd.2005.12.010
Koibuchi Nobutaka, Taniyama Yoshiaki, Nagao Kaori, Ogihara Toshio, Kaneda Yasufumi, Morishita Ryuichi 2006. "The effect of VEGF on blood vessels and blood cells during Xenopus development." Biochemical and biophysical research communications 344 (1) doi:10.1016/j.bbrc.2006.03.140
Shimamura Munehisa, Sato Naoyuki, Waguri Satoshi, Uchiyama Yasuo, Hayashi Takuya, et al. 2006. "Gene transfer of hepatocyte growth factor gene improves learning and memory in the chronic stage of cerebral infarction." Hypertension 47 (4) doi:10.1161/01.HYP.0000208598.57687.3e
Aoki Motokuni, Morishita Ryuichi 2006. "[Therapeutic angiogenesis for ischemic diseases]." Nihon rinsho. Japanese journal of clinical medicine 64 (4) doi:
Nishikawa Tomoyuki, Nakagami Hironori, Matsuki Atsushi, Maeda Akito, Yo Chiah Yian, et al. 2006. "Development of high-throughput functional screening of therapeutic genes, using a hemagglutinating virus of Japan envelope vector." Human gene therapy 17 (4) doi:10.1089/hum.2006.17.470
Nakagami Hironori, Morishita Ryuichi, Maeda Kazuhisa, Kikuchi Yasushi, Ogihara Toshio, Kaneda Yasufumi 2006. "Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy." Journal of atherosclerosis and thrombosis 13 (2) doi:
Nakagami Hironori, Tomita Naruya, Kaneda Yasufumi, Ogihara Toshio, Morishita Ryuichi 2006. "Anti-oxidant gene therapy by NF kappa B decoy oligodeoxynucleotide." Current pharmaceutical biotechnology 7 (2) doi:
Morishita Ryuichi, Tomita Naruya 2006. "[Effect of nifedipine on organ protection: potential application in patients with aortic aneurysm]." Drugs 66 Spec No 1 doi:
Kunugiza Yasuo, Tomita Tetsuya, Tomita Naruya, Morishita Ryuichi, Yoshikawa Hideki 2006. "Inhibitory effect of ribbon-type NF-kappaB decoy oligodeoxynucleotides on osteoclast induction and activity in vitro and in vivo." Arthritis research & therapy 8 (4) doi:10.1186/ar1980
Kawakami Koji, Nakajima Oumi, Morishita Ryuichi, Nagai Ryozo 2006. "Targeted anticancer immunotoxins and cytotoxic agents with direct killing moieties." TheScientificWorldJournal 6 doi:10.1100/tsw.2006.162
Inagaki Hiroshi, Suzuki Jun-ichi, Ogawa Masahito, Taniyama Yoshiaki, Morishita Ryuichi, Isobe Mitsuaki 2006. "Ultrasound-microbubble-mediated NF-kappaB decoy transfection attenuates neointimal formation after arterial injury in mice." Journal of vascular research 43 (1) doi:10.1159/000089103
Shimamura Munehisa, Sato Naoyuki, Yoshimura Shinichi, Kaneda Yasufumi, Morishita Ryuichi 2006. "HVJ-based non-viral gene transfer method: successful gene therapy using HGF and VEGF genes in experimental ischemia." Frontiers in bioscience : a journal and virtual library 11 doi:

2005

Morishita Ryuichi 2005. "A scientific rationale for the CREST trial results: evidence for the mechanism of action of cilostazol in restenosis." Atherosclerosis. Supplements 6 (4) doi:10.1016/j.atherosclerosissup.2005.09.007
Nakagami Hironori, Maeda Kazuhisa, Morishita Ryuichi, Iguchi Sota, Nishikawa Tomoyuki, et al. 2005. "Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells." Arteriosclerosis, thrombosis, and vascular biology 25 (12) doi:10.1161/01.ATV.0000190701.92007.6d
Shimamura Munehisa, Sato Naoyuki, Taniyama Yoshiaki, Kurinami Hitomi, Tanaka Hiroyuki, et al. 2005. "Gene transfer into adult rat spinal cord using naked plasmid DNA and ultrasound microbubbles." The journal of gene medicine 7 (11) doi:10.1002/jgm.793
Morishita Norio, Nakagami Hironori, Morishita Ryuichi, Takeda Shin-ichi, Mishima Fumihito, et al. 2005. "Magnetic nanoparticles with surface modification enhanced gene delivery of HVJ-E vector." Biochemical and biophysical research communications 334 (4) doi:
Tashiro Hironori, Aoki Motokuni, Isobe Mitsuaki, Hashiya Naotaka, Makino Hirofumi, et al. 2005. "Development of novel method of non-viral efficient gene transfer into neonatal cardiac myocytes." Journal of molecular and cellular cardiology 39 (3) doi:10.1016/j.yjmcc.2005.06.007
Kato Naoki, Nemoto Koichi, Nakanishi Kuniaki, Morishita Ryuichi, Kaneda Yasufumi, et al. 2005. "Nonviral HVJ (hemagglutinating virus of Japan) liposome-mediated retrograde gene transfer of human hepatocyte growth factor into rat nervous system promotes functional and histological recovery of the crushed nerve." Neuroscience research 52 (4) doi:10.1016/j.neures.2005.04.004
Makino Hirofumi, Aoki Motokuni, Hashiya Naotaka, Yamasaki Keita, Shimizu Hideo, et al. 2005. "A calcium-channel blocker, benidipine, improves forearm reactive hyperemia in patients with essential hypertension." Blood pressure. Supplement 1 doi:
Sato Naoyuki, Shimamura Munehisa, Morishita Ryuichi 2005. "Recent progress in cerebrovascular gene therapy." Current neurovascular research 2 (3) doi:
Yumoto Akihisa, Fukushima Kusano Kengo, Nakamura Kazufumi, Hashimoto Katsushi, Aoki Motokuni, et al. 2005. "Hepatocyte growth factor gene therapy reduces ventricular arrhythmia in animal models of myocardial ischemia." Acta medica Okayama 59 (3) doi:
Morishita Ryuichi, Aoki Motokuni, Ogihara Toshio 2005. "Does gene therapy become pharmacotherapy?" Experimental physiology 90 (3) doi:10.1113/expphysiol.2005.030403
Nakagami Hironori, Kaneda Yasufumi, Ogihara Toshio, Morishita Ryuichi 2005. "Hepatocyte growth factor as potential cardiovascular therapy." Expert review of cardiovascular therapy 3 (3) doi:10.1586/14779072.3.3.513
Kato Naoki, Nemoto Koichi, Nakanishi Kuniaki, Morishita Ryuichi, Kaneda Yasufumi, et al. 2005. "Nonviral gene transfer of human hepatocyte growth factor improves streptozotocin-induced diabetic neuropathy in rats." Diabetes 54 (3) doi:
Makino Hirofumi, Ogihara Toshio, Morishita Ryuichi 2005. "[Gene therapy for peripheral arterial diseases]." Nihon rinsho. Japanese journal of clinical medicine 63 (3) doi:
Nakagami Hironori, Kaneda Yasufumi, Ogihara Toshio, Morishita Ryuichi 2005. "Endothelial dysfunction in hyperglycemia as a trigger of atherosclerosis." Current diabetes reviews 1 (1) doi:
Koike Hiromi, Tomita Naruya, Azuma Haruhito, Taniyama Yoshiaki, Yamasaki Keita, et al. 2005. "An efficient gene transfer method mediated by ultrasound and microbubbles into the kidney." The journal of gene medicine 7 (1) doi:10.1002/jgm.632

2004

Tomita Naruya, Azuma Haruhito, Kaneda Yasufumi, Ogihara Toshio, Morishita Ryuichi 2004. "Application of decoy oligodeoxynucleotides-based approach to renal diseases." Current drug targets 5 (8) doi:
Hiraoka Kazuya, Yamamoto Seiji, Otsuru Satoru, Nakai Seiji, Tamai Katsuto, et al. 2004. "Enhanced tumor-specific long-term immunity of hemagglutinating [correction of hemaggluttinating] virus of Japan-mediated dendritic cell-tumor fused cell vaccination by coadministration with CpG oligodeoxynucleotides." Journal of immunology (Baltimore, Md. : 1950) 173 (7) doi:
Yamamoto Kei, Tomita Naruya, Yoshimura Shin-ichi, Nakagami Hironori, Taniyama Yoshiaki, et al. 2004. "Hypoxia-induced renal epithelial cell death through caspase-dependent pathway: role of Bcl-2, Bcl-xL and Bax in tubular injury." International journal of molecular medicine 14 (4) doi:
Katsuragi Naruto, Morishita Ryuichi, Nakamura Noriko, Ochiai Tayehito, Taniyama Yoshiaki, et al. 2004. "Periostin as a novel factor responsible for ventricular dilation." Circulation 110 (13) doi:10.1161/01.CIR.0000142607.33398.54
Yamaura Kazuhiro, Ito Ken-ichi, Tsukioka Katsuaki, Wada Yuko, Makiuchi Akiko, et al. 2004. "Suppression of acute and chronic rejection by hepatocyte growth factor in a murine model of cardiac transplantation: induction of tolerance and prevention of cardiac allograft vasculopathy." Circulation 110 (12) doi:10.1161/01.CIR.0000143052.45956.71
Morishita Ryuichi, Aoki Motokuni, Hashiya Naotaka, Makino Hirofumi, Yamasaki Keita, et al. 2004. "Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease." Hypertension 44 (2) doi:10.1161/01.HYP.0000136394.08900.ed
Hashiya Naotaka, Jo Nobuo, Aoki Motokuni, Matsumoto Kunio, Nakamura Toshikazu, et al. 2004. "In vivo evidence of angiogenesis induced by transcription factor Ets-1: Ets-1 is located upstream of angiogenesis cascade." Circulation 109 (24) doi:10.1161/01.CIR.0000130643.41587.DB
Kotani Hitoshi, Nakajima Toshihiro, Lai Shoupeng, Morishita Ryuichi, Kaneda Yasufumi 2004. "The HVJ-envelope as an innovative vector system for cardiovascular disease." Current gene therapy 4 (2) doi:
Morishita Ryuichi, Aoki Motokuni, Hashiya Naotaka, Yamasaki Keita, Kurinami Hitomi, et al. 2004. "Therapeutic angiogenesis using hepatocyte growth factor (HGF)." Current gene therapy 4 (2) doi:
Powell Richard J, Dormandy John, Simons Michael, Morishita Ryuichi, Annex Brian H 2004. "Therapeutic angiogenesis for critical limb ischemia: design of the hepatocyte growth factor therapeutic angiogenesis clinical trial." Vascular medicine (London, England) 9 (3) doi:
Tomita Naruya, Kim John Y S, Gibbons Gary H, Zhang Lunan, Kaneda Yasufumi, et al. 2004. "Gene therapy with an E2F transcription factor decoy inhibits cell cycle progression in rat anti-Thy 1 glomerulonephritis." International journal of molecular medicine 13 (5) doi:
Nakagami Hironori, Morishita Ryuichi, Nishikawa Tomoyuki, Shimizu Hideo, Iguchi Sota, et al. 2004. "Lack of association between the hepatocyte growth factor receptor, c-met, and the anti-apoptotic action of bag-1 in endothelial cells." Hypertension research : official journal of the Japanese Society of Hypertension 27 (5) doi:
Morishita Ryuichi 2004. "Perspective in progress of cardiovascular gene therapy." Journal of pharmacological sciences 95 (1) doi:
Koibuchi Nobutaka, Kaneda Yasufumi, Taniyama Yoshiaki, Matsumoto Kunio, Nakamura Toshikazu, et al. 2004. "Essential role of HGF (hepatocyte growth factor) in blood formation in Xenopus." Blood 103 (9) doi:10.1182/blood-2003-02-0352
Hashiya Naotaka, Aoki Motokuni, Tachibana Katsuro, Taniyama Yoshiaki, Yamasaki Keita, et al. 2004. "Local delivery of E2F decoy oligodeoxynucleotides using ultrasound with microbubble agent (Optison) inhibits intimal hyperplasia after balloon injury in rat carotid artery model." Biochemical and biophysical research communications 317 (2) doi:10.1016/j.bbrc.2004.03.070
Morishita Ryuichi, Tomita Naruya, Kaneda Yasufumi, Ogihara Toshio 2004. "Molecular therapy to inhibit NFkappaB activation by transcription factor decoy oligonucleotides." Current opinion in pharmacology 4 (2) doi:10.1016/j.coph.2003.10.008
Matsuki Atsushi, Yamamoto Seiji, Nakagami Hironori, Aoki Motokuni, Tamai Katsuto, et al. 2004. "No influence of tumor growth by intramuscular injection of hepatocyte growth factor plasmid DNA: safety evaluation of therapeutic angiogenesis gene therapy in mice." Biochemical and biophysical research communications 315 (1) doi:10.1016/j.bbrc.2004.01.026
Makino Hirofumi, Aoki Motokuni, Hashiya Naotaka, Yamasaki Keita, Hiraoka Kazuya, et al. 2004. "Increase in peripheral blood flow by intravenous administration of prostaglandin E1 in patients with peripheral arterial disease, accompanied by up-regulation of hepatocyte growth factor." Hypertension research : official journal of the Japanese Society of Hypertension 27 (2) doi:
Shimamura Munehisa, Sato Naoyuki, Oshima Kazuo, Aoki Motokuni, Kurinami Hitomi, et al. 2004. "Novel therapeutic strategy to treat brain ischemia: overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model." Circulation 109 (3) doi:10.1161/01.CIR.0000109496.82683.49
Nakashima Hideki, Aoki Motokuni, Miyake Takashi, Kawasaki Tomio, Iwai Masahiro, et al. 2004. "Inhibition of experimental abdominal aortic aneurysm in the rat by use of decoy oligodeoxynucleotides suppressing activity of nuclear factor kappaB and ets transcription factors." Circulation 109 (1) doi:10.1161/01.CIR.0000105725.61763.A2
Namiki Masayuki, Kawashima Seinosuke, Yamashita Tomoya, Ozaki Masanori, Sakoda Tsuyoshi, et al. 2004. "Intramuscular gene transfer of interleukin-10 cDNA reduces atherosclerosis in apolipoprotein E-knockout mice." Atherosclerosis 172 (1) doi:
Taniyama Yoshiaki, Tomita Naruya, Endoh Seiji, Kaneda Yasufumi, Ogihara Toshio, Morishita Ryuichi 2004. "[Gene transfer with ultrasound and microbubbles (optison) as a potential treatment for cardiovascular diseases]." Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 41 (1) doi:
Oshima Kazuo, Shimamura Munehisa, Mizuno Shinya, Tamai Katsuto, Doi Katsumi, et al. 2004. "Intrathecal injection of HVJ-E containing HGF gene to cerebrospinal fluid can prevent and ameliorate hearing impairment in rats." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 18 (1) doi:10.1096/fj.03-0567fje

2003

Wada Yuko, Fujimori Minoru, Suzuki Jun-ichi, Tsukioka Katsuaki, Ito Ken-ichi, et al. 2003. "Egr-1 in vascular smooth muscle cell proliferation in response to allo-antigen." The Journal of surgical research 115 (2) doi:
Hiraoka Kazuya, Koike Hiromi, Yamamoto Seiji, Tomita Naruya, Yokoyama Chieko, et al. 2003. "Enhanced therapeutic angiogenesis by cotransfection of prostacyclin synthase gene or optimization of intramuscular injection of naked plasmid DNA." Circulation 108 (21) doi:10.1161/01.CIR.0000093275.78676.F4
Namba Tsunetatsu, Koike Hiromi, Murakami Kazushi, Aoki Motokuni, Makino Hirofumi, et al. 2003. "Angiogenesis induced by endothelial nitric oxide synthase gene through vascular endothelial growth factor expression in a rat hindlimb ischemia model." Circulation 108 (18) doi:10.1161/01.CIR.0000093190.53478.78
Tomita Naruya, Ogihara Toshio, Morishita Ryuichi 2003. "Transcription factors as molecular targets: molecular mechanisms of decoy ODN and their design." Current drug targets 4 (8) doi:
Aoki Motokuni, Morishita Ryuichi, Ogihara Toshio 2003. "Oligonucleotide-based molecular therapy for restenosis after angioplasty." Current drug targets 4 (8) doi:
Tomita Naruya, Ogihara Toshio, Morishita Ryuichi 2003. "Therapeutic potential of decoy oligonucleotides strategy in cardiovascular diseases." Expert review of cardiovascular therapy 1 (3) doi:10.1586/14779072.1.3.463
Kokuzawa Jouji, Yoshimura Shinichi, Kitajima Hideomi, Shinoda Jun, Kaku Yasuhiko, et al. 2003. "Hepatocyte growth factor promotes proliferation and neuronal differentiation of neural stem cells from mouse embryos." Molecular and cellular neurosciences 24 (1) doi:
Ogushi Ichiro, Iimuro Yuji, Seki Ekihiro, Son Gakuhei, Hirano Tadamichi, et al. 2003. "Nuclear factor kappa B decoy oligodeoxynucleotides prevent endotoxin-induced fatal liver failure in a murine model." Hepatology (Baltimore, Md.) 38 (2) doi:10.1053/jhep.2003.50298
Lan Hui Y, Mu Wei, Tomita Naruya, Huang Xiao R, Li Jin H, et al. 2003. "Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model." Journal of the American Society of Nephrology : JASN 14 (6) doi:
Hayashi Shin-ichiro, Azuma Junya, Ogihara Toshio, Morishita Ryuichi 2003. "[Gene therapy for myocardial regeneration]." Nihon rinsho. Japanese journal of clinical medicine 61 (5) doi:
Kato Naoki, Nakanishi Kuniaki, Nemoto Koichi, Morishita Ryuichi, Kaneda Yasufumi, et al. 2003. "Efficient gene transfer from innervated muscle into rat peripheral and central nervous systems using a non-viral haemagglutinating virus of Japan (HVJ)-liposome method." Journal of neurochemistry 85 (3) doi:
Tomita Naruya, Azuma Haruhito, Kaneda Yasufumi, Ogihara Toshio, Morishita Ryuichi 2003. "Gene therapy with transcription factor decoy oligonucleotides as a potential treatment for cardiovascular diseases." Current drug targets 4 (4) doi:
Koike Hiromi, Morishita Ryuichi, Iguchi Sohta, Aoki Motokuni, Matsumoto Kunio, et al. 2003. "Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 17 (6) doi:10.1096/fj.02-0754fje
Tomita Naruya, Tomita Tetsuya, Yuyama Kazuhiko, Tougan Takahiro, Tajima Tsuyoshi, et al. 2003. "Development of novel decoy oligonucleotides: advantages of circular dumb-bell decoy." Current opinion in molecular therapeutics 5 (2) doi:
Tomita Naruya, Morishita Ryuichi, Taniyama Yoshiaki, Koike Hiromi, Aoki Motokuni, et al. 2003. "Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis, ets-1." Circulation 107 (10) doi:
Yamamoto Seiji, Yamano Tomoki, Tanaka Maki, Hoon Dave S B, Takao Sonshin, et al. 2003. "A novel combination of suicide gene therapy and histone deacetylase inhibitor for treatment of malignant melanoma." Cancer gene therapy 10 (3) doi:10.1038/sj.cgt.7700551
Matsumoto Keiko, Morishita Ryuichi, Tomita N, Moriguchi Atsushi, Komai Norio, et al. 2003. "Improvement of endothelial dysfunction by angiotensin II blockade accompanied by induction of vascular hepatocyte growth factor system in diabetic spontaneously hypertensive rats." Heart and vessels 18 (1) doi:10.1007/s003800300003
Sekiguchi Keishi, Yasuzumi Fumioki, Morishita Ryuichi 2003. "Exogenous expression of hepatocyte growth factor (HGF) in rat striatum by naked plasmid DNA." Neuroscience research 45 (2) doi:
Shimamura Munehisa, Morishita Ryuichi, Endoh Masayuki, Oshima Kazuo, Aoki Motokuni, et al. 2003. "HVJ-envelope vector for gene transfer into central nervous system." Biochemical and biophysical research communications 300 (2) doi:
Morishita Ryuichi, Kaneda Yasufumi, Ogihara Toshio 2003. "Therapeutic potential of oligonucleotide-based therapy in cardiovascular disease." BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 17 (6) doi:

2002

Tsukioka Katsuaki, Suzuki Jun ichi, Fujimori Minoru, Wada Yuko, Yamaura Kazuhiro, et al. 2002. "Expression of matrix metalloproteinases in cardiac allograft vasculopathy and its attenuation by anti MMP-2 ribozyme gene transfection." Cardiovascular research 56 (3) doi:
Morishita Ryuichi 2002. "Recent progress in gene therapy for cardiovascular disease." Circulation journal : official journal of the Japanese Circulation Society 66 (12) doi:
Nakanishi Kuniaki, Uenoyama Maki, Tomita Naruya, Morishita Ryuichi, Kaneda Yasufumi, et al. 2002. "Gene transfer of human hepatocyte growth factor into rat skin wounds mediated by liposomes coated with the sendai virus (hemagglutinating virus of Japan)." The American journal of pathology 161 (5) doi:10.1016/S0002-9440(10)64453-7
Morishita Ryuichi 2002. "[Gene therapy in cardiovascular medicine as new pharmacological therapy]." Nihon yakurigaku zasshi. Folia pharmacologica Japonica 120 (4) doi:
Morishita Ryuichi, Tomita Naruya, Ogihara Toshio 2002. "HMG-Co A reductase inhibitors in the treatment of cardiovascular diseases: stabilization of coronary artery plaque." Current drug targets 3 (5) doi:
Komai Norio, Morishita Ryuichi, Yamada Shingo, Oishi Mitsuru, Iguchi Sota, et al. 2002. "Mitogenic activity of oxidized lipoprotein (a) on human vascular smooth muscle cells." Hypertension 40 (3) doi:
Aoki Motokuni, Ogihara Toshio, Morishita Ryuichi 2002. "[The latest review of therapeutic angiogenesis using angiogenic growth factors to peripheral arterial diseases]." Nihon rinsho. Japanese journal of clinical medicine 60 (9) doi:
Tomita Naruya, Morishita Ryuichi, Koike Hiromi, Hashizume Masahide, Notake Mitsue, et al. 2002. "Therapeutic approach to familial hypercholesterolemia by HVJ-liposomes in LDL receptor knockout mouse." International journal of molecular medicine 10 (2) doi:
Nakagami Hironori, Morishita Ryuichi, Yamamoto Kei, Taniyama Yoshiaki, Aoki Motokuni, et al. 2002. "Hepatocyte growth factor prevents endothelial cell death through inhibition of bax translocation from cytosol to mitochondrial membrane." Diabetes 51 (8) doi:
Kaneda Yasufumi, Nakajima Toshihiro, Nishikawa Tomoyuki, Yamamoto Seiji, Ikegami Hiroyuki, et al. 2002. "Hemagglutinating virus of Japan (HVJ) envelope vector as a versatile gene delivery system." Molecular therapy : the journal of the American Society of Gene Therapy 6 (2) doi:
Taniyama Yoshiaki, Morishita Ryuichi, Aoki Motokuni, Hiraoka Kazuya, Yamasaki Keita, et al. 2002. "Angiogenesis and antifibrotic action by hepatocyte growth factor in cardiomyopathy." Hypertension 40 (1) doi:
Ahn Jong Deok, Morishita Ryuichi, Kaneda Yasufumi, Lee Sang-Jun, Kwon Ki-Young, et al. 2002. "Inhibitory effects of novel AP-1 decoy oligodeoxynucleotides on vascular smooth muscle cell proliferation in vitro and neointimal formation in vivo." Circulation research 90 (12) doi:
Morishita Ryuichi, Aoki Motokuni, Yo Yoshikage, Ogihara Toshio 2002. "Hepatocyte growth factor as cardiovascular hormone: role of HGF in the pathogenesis of cardiovascular disease." Endocrine journal 49 (3) doi:
Jo Nobuo, Ogata Nahoko, Aoki Motokuni, Otsuji Tsuyoshi, Morishita Ryuichi, et al. 2002. "Effective transfection of a cis element "decoy" of the nuclear factor-kappaB binding site into the experimental choroidal neovascularization." Current eye research 24 (6) doi:
Komai Norio, Ohishi Mitsuru, Morishita Ryuichi, Moriguchi Atsushi, Kaibe Masaharu, et al. 2002. "Serum hepatocyte growth factor concentration is correlated with the forearm vasodilator response in hypertensive patients." American journal of hypertension 15 (6) doi:
Yoshimura Shin-Ichi, Morishita Ryuichi, Hayashi Katsuhiko, Kokuzawa Jouji, Aoki Motokuni, et al. 2002. "Gene transfer of hepatocyte growth factor to subarachnoid space in cerebral hypoperfusion model." Hypertension 39 (5) doi:
Tomita Naruya, Morishita Ryuichi, Ogihara Toshio 2002. "[Pharmacological effects of HMG-CoA reductase inhibitors]." Nihon rinsho. Japanese journal of clinical medicine 60 (5) doi:
Endoh Masayuki, Koibuchi Nobutaka, Sato Manabu, Morishita Ryuichi, Kanzaki Toru, et al. 2002. "Fetal gene transfer by intrauterine injection with microbubble-enhanced ultrasound." Molecular therapy : the journal of the American Society of Gene Therapy 5 (5 Pt 1) doi:10.1006/mthe.2002.0577
Mori Masaki, Nakagami Hironori, Morishita Ryuichi, Mitsuda Noriaki, Yamamoto Kei, et al. 2002. "N141I mutant presenilin-2 gene enhances neuronal cell death and decreases bcl-2 expression." Life sciences 70 (21) doi:
Tomita Naruya, Morishita Ryuichi, Tomita Tetsuya, Ogihara Toshio 2002. "Potential therapeutic applications of decoy oligonucleotides." Current opinion in molecular therapeutics 4 (2) doi:
Morishita Ryuichi, Sakaki Minako, Yamamoto Kei, Iguchi Sota, Aoki Motokuni, et al. 2002. "Impairment of collateral formation in lipoprotein(a) transgenic mice: therapeutic angiogenesis induced by human hepatocyte growth factor gene." Circulation 105 (12) doi:
Taniyama Yoshiaki, Tachibana Katsuro, Hiraoka Kazuya, Namba Tsunetatsu, Yamasaki Keita, et al. 2002. "Local delivery of plasmid DNA into rat carotid artery using ultrasound." Circulation 105 (10) doi:
Ishida Akihiko, Kawakami Hirochika, Yasuzumi Fumioki, Morishita Ryuichi 2002. "[Gene therapy for cerebral infarction (cerebral ischemia)]." Nō to shinkei = Brain and nerve 54 (3) doi:
Tomita Naruya, Morishita Ryuichi, Yamamoto Kei, Higaki Jitsuo, Dzau Victor J, et al. 2002. "Targeted gene therapy for rat glomerulonephritis using HVJ-immunoliposomes." The journal of gene medicine 4 (5) doi:10.1002/jgm.300
Nakamura Hiroshige, Morishita Ryuichi, Kaneda Yasufumi 2002. "Molecular therapy via transcriptional regulation with double-stranded oligodeoxynucleotides as decoys." In vivo (Athens, Greece) 16 (1) doi:
Namiki Masayuki, Kawashima Seinosuke, Yamashita Tomoya, Ozaki Masanori, Hirase Tetsuaki, et al. 2002. "Local overexpression of monocyte chemoattractant protein-1 at vessel wall induces infiltration of macrophages and formation of atherosclerotic lesion: synergism with hypercholesterolemia." Arteriosclerosis, thrombosis, and vascular biology 22 (1) doi: