MacNee William

Top coauthors of MacNee William

Tal-Singer Ruth (24 papers)

Lomas David A (20 papers)

Rennard Stephen I (18 papers)

Vestbo Jørgen (18 papers)

Silverman Edwin K (16 papers)

List of MacNee William publications

2017

Mantoani Leandro Cruz, Dell'Era Silvina, MacNee William, Rabinovich Roberto A 2017. "Physical activity in patients with COPD: the impact of comorbidities." Expert review of respiratory medicine 11 (9) doi:10.1080/17476348.2017.1354699
Lakhdar Ramzi, Drost Ellen M, MacNee William, Bastos Ricardo, Rabinovich Roberto A 2017. "2D-DIGE proteomic analysis of vastus lateralis from COPD patients with low and normal fat free mass index and healthy controls." Respiratory research 18 (1) doi:10.1186/s12931-017-0525-x
Hobbs Brian D, de Jong Kim, Lamontagne Maxime, Bossé Yohan, Shrine Nick, et al. 2017. "Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis." Nature genetics 49 (3) doi:10.1038/ng.3752
Chen Delphine L, Cheriyan Joseph, Chilvers Edwin R, Choudhury Gourab, Coello Christopher, et al. 2017. "Quantification of Lung PET Images: Challenges and Opportunities." Journal of nuclear medicine : official publication, Society of Nuclear Medicine 58 (2) doi:10.2967/jnumed.116.184796
Suntharalingam Jay, Wilkinson Tom, Annandale Joseph, Davey Claire, Fielding Rhea, et al. 2017. "British Thoracic Society quality standards for home oxygen use in adults." BMJ open respiratory research 4 (1) doi:10.1136/bmjresp-2017-000223
Martin Mickaël, Almeras Natalie, Després Jean-Pierre, Coxson Harvey O, Washko George R, et al. 2017. "Ectopic fat accumulation in patients with COPD: an ECLIPSE substudy." International journal of chronic obstructive pulmonary disease 12 doi:10.2147/COPD.S124750
Rubio Noah, Parker Richard A, Drost Ellen M, Pinnock Hilary, Weir Christopher J, et al. 2017. "Home monitoring of breathing rate in people with chronic obstructive pulmonary disease: observational study of feasibility, acceptability, and change after exacerbation." International journal of chronic obstructive pulmonary disease 12 doi:10.2147/COPD.S120706

2016

MacNee William 2016. "Is Chronic Obstructive Pulmonary Disease an Accelerated Aging Disease?" Annals of the American Thoracic Society 13 (Supplement_5) doi:10.1513/AnnalsATS.201602-124AW
Mirsadraee Saeed, Reid John H, Connell Martin, MacNee William, Hirani Nikhil, et al. 2016. "Dynamic (4D) CT perfusion offers simultaneous functional and anatomical insights into pulmonary embolism resolution." European journal of radiology 85 (10) doi:10.1016/j.ejrad.2016.08.018
Andrianopoulos Vasileios, Celli Bartolome R, Franssen Frits M E, Pinto-Plata Victor M, Calverley Peter M A, et al. 2016. "Determinants of exercise-induced oxygen desaturation including pulmonary emphysema in COPD: Results from the ECLIPSE study." Respiratory medicine 119 doi:10.1016/j.rmed.2016.08.023
Choudhury Gourab, MacNee William 2016. "Role of Inflammation and Oxidative Stress in the Pathology of Ageing in COPD: Potential Therapeutic Interventions." COPD doi:10.1080/15412555.2016.1214948
Mantoani Leandro Cruz, Rubio Noah, McKinstry Brian, MacNee William, Rabinovich Roberto A 2016. "Interventions to modify physical activity in patients with COPD: a systematic review." The European respiratory journal doi:10.1183/13993003.01744-2015
Rabinovich Roberto A, Miller Bruce E, Wrobel Karolina, Ranjit Kareshma, Williams Michelle C, et al. 2016. "Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD." The European respiratory journal doi:10.1183/13993003.01824-2015
Putman Rachel K, Hatabu Hiroto, Araki Tetsuro, Gudmundsson Gunnar, Gao Wei, et al. 2016. "Association Between Interstitial Lung Abnormalities and All-Cause Mortality." JAMA 315 (7) doi:10.1001/jama.2016.0518
Lange Peter, Halpin David M, O'Donnell Denis E, MacNee William 2016. "Diagnosis, assessment, and phenotyping of COPD: beyond FEV1." International journal of chronic obstructive pulmonary disease 11 Spec Iss doi:10.2147/COPD.S85976
Parker Richard A, Weir Christopher J, Rubio Noah, Rabinovich Roberto, Pinnock Hilary, et al. 2016. "Application of Mixed Effects Limits of Agreement in the Presence of Multiple Sources of Variability: Exemplar from the Comparison of Several Devices to Measure Respiratory Rate in COPD Patients." PloS one 11 (12) doi:10.1371/journal.pone.0168321

2015

Andrianopoulos Vasileios, Wouters Emiel F M, Pinto-Plata Victor M, Vanfleteren Lowie E G W, Bakke Per S, et al. 2015. "Prognostic value of variables derived from the six-minute walk test in patients with COPD: Results from the ECLIPSE study." Respiratory medicine 109 (9) doi:10.1016/j.rmed.2015.06.013
Kendall Marilyn, Buckingham Susan, Ferguson Susie, MacNee William, Sheikh Aziz, et al. 2015. "Exploring the concept of need in people with very severe chronic obstructive pulmonary disease: a qualitative study." BMJ supportive & palliative care doi:10.1136/bmjspcare-2015-000904
Rabinovich Roberto A, MacNee William 2015. "Should we treat chronic obstructive pulmonary disease as a cardiovascular disease?" Expert review of respiratory medicine 9 (4) doi:10.1586/17476348.2015.1070099
Sun Xue-Jiao, Li Zhan-Hua, Zhang Yang, Zhou Guang, Zhang Jian-Quan, et al. 2015. "Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR expression." American journal of physiology. Lung cellular and molecular physiology 309 (2) doi:10.1152/ajplung.00292.2014
Hardinge Maxine, Annandale Joe, Bourne Simon, Cooper Brendan, Evans Angela, et al. 2015. "British Thoracic Society guidelines for home oxygen use in adults." Thorax 70 Suppl 1 doi:10.1136/thoraxjnl-2015-206865
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar A, et al. 2015. "An official American Thoracic Society/European Respiratory Society statement: research questions in COPD." European respiratory review : an official journal of the European Respiratory Society 24 (136) doi:10.1183/16000617.00000315
Wilke Sarah, Jones Paul W, Müllerova H, Vestbo Jørgen, Tal-Singer Ruth, et al. 2015. "One-year change in health status and subsequent outcomes in COPD." Thorax 70 (5) doi:10.1136/thoraxjnl-2014-205697
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar, et al. 2015. "An official American Thoracic Society/European Respiratory Society statement: research questions in COPD." The European respiratory journal 45 (4) doi:10.1183/09031936.00009015
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar, et al. 2015. "An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 191 (7) doi:10.1164/rccm.201501-0044ST
Thomson Neil C, Chaudhuri Rekha, Spears Mark, Messow Claudia-Martina, MacNee William, et al. 2015. "Poor symptom control is associated with reduced CT scan segmental airway lumen area in smokers with asthma." Chest 147 (3) doi:10.1378/chest.14-1119
Rennard Stephen I, Locantore Nicholas, Delafont Bruno, Tal-Singer Ruth, Silverman Edwin K, et al. 2015. "Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis." Annals of the American Thoracic Society 12 (3) doi:10.1513/AnnalsATS.201403-125OC
Cazzola Mario, Hanania Nicola Alexander, MacNee William, Rüdell Katja, Hackford Claire, Tamimi Nihad 2015. "A review of the most common patient-reported outcomes in COPD--revisiting current knowledge and estimating future challenges." International journal of chronic obstructive pulmonary disease 10 doi:10.2147/COPD.S77368
Buckingham Susan, Kendall Marilyn, Ferguson Susie, MacNee William, Sheikh Aziz, et al. 2015. "HELPing older people with very severe chronic obstructive pulmonary disease (HELP-COPD): mixed-method feasibility pilot randomised controlled trial of a novel intervention." NPJ primary care respiratory medicine 25 doi:10.1038/npjpcrm.2015.20
Rabinovich Roberto A, Drost Ellen, Manning Jonathan R, Dunbar Donald R, Díaz-Ramos MaCarmen, et al. 2015. "Genome-wide mRNA expression profiling in vastus lateralis of COPD patients with low and normal fat free mass index and healthy controls." Respiratory research 16 doi:10.1186/s12931-014-0139-5

2014

MacNee William, Rabinovich Roberto A, Choudhury Gourab 2014. "Ageing and the border between health and disease." The European respiratory journal 44 (5) doi:10.1183/09031936.00134014
McDonald Merry-Lynn N, Cho Michael H, Sørheim Inga-Cecilie, Lutz Sharon M, Castaldi Peter J, et al. 2014. "Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 51 (5) doi:10.1165/rcmb.2014-0135OC
Chaudhuri Rekha, McSharry Charles, Brady Jeffrey, Grierson Christal, Messow C Martina, et al. 2014. "Low sputum MMP-9/TIMP ratio is associated with airway narrowing in smokers with asthma." The European respiratory journal 44 (4) doi:10.1183/09031936.00047014
Diaz Alejandro A, Zhou Linfu, Young Tom P, McDonald Merry-Lynn, Harmouche Rola, et al. 2014. "Chest CT measures of muscle and adipose tissue in COPD: gender-based differences in content and in relationships with blood biomarkers." Academic radiology 21 (10) doi:10.1016/j.acra.2014.05.013
Mohan Divya, Gale Nichola S, McEniery Carmel M, Bolton Charlotte E, Cockcroft John R, et al. 2014. "Evaluating the role of inflammation in chronic airways disease: the ERICA study." COPD 11 (5) doi:10.3109/15412555.2014.898031
Williams Michelle C, Murchison John T, Edwards Lisa D, Agustí Alvar, Bakke Per, et al. 2014. "Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality." Thorax 69 (8) doi:10.1136/thoraxjnl-2012-203151
Faner Rosa, Tal-Singer Ruth, Riley John H, Celli Bartolomé, Vestbo Jørgen, et al. 2014. "Lessons from ECLIPSE: a review of COPD biomarkers." Thorax 69 (7) doi:10.1136/thoraxjnl-2013-204778
Hanson Corrine, Sayles Harlan, Rutten Erica E P A, Wouters E F M, MacNee William, et al. 2014. "The Association Between Dietary Intake and Phenotypical Characteristics of COPD in the ECLIPSE Cohort." Chronic obstructive pulmonary diseases (Miami, Fla.) 1 (1) doi:10.15326/jcopdf.1.1.2014.0113
Vestbo Jørgen, Agusti Alvar, Wouters Emiel F M, Bakke Per, Calverley Peter M A, et al. 2014. "Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team." American journal of respiratory and critical care medicine 189 (9) doi:10.1164/rccm.201311-2006PP
Choudhury Gourab, Rabinovich Roberto, MacNee William 2014. "Comorbidities and systemic effects of chronic obstructive pulmonary disease." Clinics in chest medicine 35 (1) doi:10.1016/j.ccm.2013.10.007

2013

Chaudhuri Rekha, McSharry Charles, Spears Mark, Brady Jeffrey, Grierson Christal, et al. 2013. "Sputum matrix metalloproteinase-9 is associated with the degree of emphysema on computed tomography in COPD." Translational respiratory medicine 1 (1) doi:10.1186/2213-0802-1-11
Cheng Donavan T, Kim Deog Kyeom, Cockayne Debra A, Belousov Anton, Bitter Hans, et al. 2013. "Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 188 (8) doi:10.1164/rccm.201302-0247OC
Thomson Neil C, Chaudhuri Rekha, Messow C Martina, Spears Mark, MacNee William, et al. 2013. "Chronic cough and sputum production are associated with worse clinical outcomes in stable asthma." Respiratory medicine 107 (10) doi:10.1016/j.rmed.2013.07.017
MacNee William 2013. "Systemic inflammatory biomarkers and co-morbidities of chronic obstructive pulmonary disease." Annals of medicine 45 (3) doi:10.3109/07853890.2012.732703
Maclay John D, MacNee William 2013. "Cardiovascular disease in COPD: mechanisms." Chest 143 (3) doi:10.1378/chest.12-0938
Polkey Michael I, Spruit Martijn A, Edwards Lisa D, Watkins Michael L, Pinto-Plata Victor, et al. 2013. "Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization." American journal of respiratory and critical care medicine 187 (4) doi:10.1164/rccm.201209-1596OC
McAllister David A, Wild Sarah H, MacLay John D, Robson Andrew, Newby David E, et al. 2013. "Forced expiratory volume in one second predicts length of stay and in-hospital mortality in patients undergoing cardiac surgery: a retrospective cohort study." PloS one 8 (5) doi:10.1371/journal.pone.0064565
Romme Elisabeth A P M, McAllister David A, Murchison John T, Van Beek Edwin J R, Petrides George S, et al. 2013. "Associations between COPD related manifestations: a cross-sectional study." Respiratory research 14 doi:10.1186/1465-9921-14-129
Pinnock Hilary, Hanley Janet, McCloughan Lucy, Todd Allison, Krishan Ashma, et al. 2013. "Effectiveness of telemonitoring integrated into existing clinical services on hospital admission for exacerbation of chronic obstructive pulmonary disease: researcher blind, multicentre, randomised controlled trial." BMJ (Clinical research ed.) 347 doi:
Cho Wan-Seob, Duffin Rodger, Bradley Mark, Megson Ian L, MacNee William, et al. 2013. "Predictive value of in vitro assays depends on the mechanism of toxicity of metal oxide nanoparticles." Particle and fibre toxicology 10 (1) doi:10.1186/1743-8977-10-55

2012

Kim Deog Kyeom, Cho Michael H, Hersh Craig P, Lomas David A, Miller Bruce E, et al. 2012. "Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 186 (12) doi:10.1164/rccm.201206-1013OC
Ubhi Baljit K, Cheng Kian Kai, Dong Jiyang, Janowitz Tobias, Jodrell Duncan, et al. 2012. "Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD." Molecular bioSystems 8 (12) doi:10.1039/c2mb25194a
Giavedoni Santiago, Deans Andrew, McCaughey Paul, Drost Ellen, MacNee William, Rabinovich Roberto A 2012. "Neuromuscular electrical stimulation prevents muscle function deterioration in exacerbated COPD: a pilot study." Respiratory medicine 106 (10) doi:10.1016/j.rmed.2012.05.005
Ubhi Baljit K, Riley John H, Shaw Paul A, Lomas David A, Tal-Singer Ruth, et al. 2012. "Metabolic profiling detects biomarkers of protein degradation in COPD patients." The European respiratory journal 40 (2) doi:10.1183/09031936.00112411
Rahman Irfan, MacNee William 2012. "Antioxidant pharmacological therapies for COPD." Current opinion in pharmacology 12 (3) doi:10.1016/j.coph.2012.01.015
Maio Sara, Sherrill Duane L, MacNee William, Lange Peter, Costabel Ulrich, et al. 2012. "The European Respiratory Society spirometry tent: a unique form of screening for airway obstruction." The European respiratory journal 39 (6) doi:10.1183/09031936.00111910
Celli Bartolome R, Locantore Nicholas, Yates Julie, Tal-Singer Ruth, Miller Bruce E, et al. 2012. "Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 185 (10) doi:10.1164/rccm.201110-1792OC
Barr R Graham, Berkowitz Eugene A, Bigazzi Francesca, Bode Frederick, Bon Jessica, et al. 2012. "A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation." COPD 9 (2) doi:10.3109/15412555.2012.654923
Ure Jenny, Pinnock Hilary, Hanley Janet, Kidd Gillian, McCall Smith Emily, et al. 2012. "Piloting tele-monitoring in COPD: a mixed methods exploration of issues in design and implementation." Primary care respiratory journal : journal of the General Practice Airways Group 21 (1) doi:10.4104/pcrj.2011.00065
Spruit Martijn A, Polkey Michael I, Celli Bartolome, Edwards Lisa D, Watkins Michael L, et al. 2012. "Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease." Journal of the American Medical Directors Association 13 (3) doi:10.1016/j.jamda.2011.06.009
Cho Michael H, Castaldi Peter J, Wan Emily S, Siedlinski Mateusz, Hersh Craig P, et al. 2012. "A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13." Human molecular genetics 21 (4) doi:10.1093/hmg/ddr524
Schinwald Anja, Murphy Fiona A, Jones Alan, MacNee William, Donaldson Ken 2012. "Graphene-based nanoplatelets: a new risk to the respiratory system as a consequence of their unusual aerodynamic properties." ACS nano 6 (1) doi:10.1021/nn204229f
Agustí Alvar, Edwards Lisa D, Rennard Stephen I, MacNee William, Tal-Singer Ruth, et al. 2012. "Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype." PloS one 7 (5) doi:10.1371/journal.pone.0037483

2011

Doehner Wolfram, Haeusler Karl Georg, Endres Matthias, Anker Stefan D, MacNee William, Lainscak Mitja 2011. "Neurological and endocrinological disorders: orphans in chronic obstructive pulmonary disease." Respiratory medicine 105 Suppl 1 doi:10.1016/S0954-6111(11)70005-1
Vestbo Jørgen, Edwards Lisa D, Scanlon Paul D, Yates Julie C, Agusti Alvar, et al. 2011. "Changes in forced expiratory volume in 1 second over time in COPD." The New England journal of medicine 365 (13) doi:10.1056/NEJMoa1105482
Maclay John D, McAllister David A, Johnston Shonna, Raftis Jennifer, McGuinnes Catherine, et al. 2011. "Increased platelet activation in patients with stable and acute exacerbation of COPD." Thorax 66 (9) doi:10.1136/thx.2010.157529
Pinnock Hilary, Kendall Marilyn, Murray Scott A, Worth Allison, Levack Pamela, et al. 2011. "Living and dying with severe chronic obstructive pulmonary disease: multi-perspective longitudinal qualitative study." BMJ supportive & palliative care 1 (2) doi:10.1136/bmjspcare.d142rep
MacNee William, Rennard Stephen I, Hunt John F, Edwards Lisa D, Miller Bruce E, et al. 2011. "Evaluation of exhaled breath condensate pH as a biomarker for COPD." Respiratory medicine 105 (7) doi:10.1016/j.rmed.2011.02.009
McAllister David A, MacNee William, Duprez Daniel, Hoffman Eric A, Vogel-Claussen Jens, et al. 2011. "Pulmonary function is associated with distal aortic calcium, not proximal aortic distensibility. MESA lung study." COPD 8 (2) doi:10.3109/15412555.2011.558543
Rabinovich Roberto A, MacNee William 2011. "Chronic obstructive pulmonary disease and its comorbidities." British journal of hospital medicine (London, England : 2005) 72 (3) doi:
Chappell Sally L, Daly Leslie, Lotya Juzer, Alsaegh Aiman, Guetta-Baranes Tamar, et al. 2011. "The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study." BMC medical genetics 12 doi:10.1186/1471-2350-12-24
Pinnock Hilary, Kendall Marilyn, Murray Scott A, Worth Allison, Levack Pamela, et al. 2011. "Living and dying with severe chronic obstructive pulmonary disease: multi-perspective longitudinal qualitative study." BMJ (Clinical research ed.) 342 doi:

2010

Cho Wan-Seob, Duffin Rodger, Poland Craig A, Howie Sarah E M, MacNee William, et al. 2010. "Metal oxide nanoparticles induce unique inflammatory footprints in the lung: important implications for nanoparticle testing." Environmental health perspectives 118 (12) doi:10.1289/ehp.1002201
Mair Grant, Maclay John, Miller Joy J, McAllister David, Connell Martin, et al. 2010. "Airway dimensions in COPD: relationships with clinical variables." Respiratory medicine 104 (11) doi:10.1016/j.rmed.2010.04.021
He Zhi-Yi, Ou Li-Mei, Zhang Jian-Quan, Bai Jing, Liu Guang-Nan, et al. 2010. "Effect of 6 months of erythromycin treatment on inflammatory cells in induced sputum and exacerbations in chronic obstructive pulmonary disease." Respiration; international review of thoracic diseases 80 (6) doi:10.1159/000321374
Haq Imran, Chappell Sally, Johnson Simon R, Lotya Juzer, Daly Leslie, et al. 2010. "Association of MMP-2 polymorphisms with severe and very severe COPD: a case control study of MMPs-1, 9 and 12 in a European population." BMC medical genetics 11 doi:10.1186/1471-2350-11-7
Agusti Alvar, Calverley Peter M A, Celli Bartolome, Coxson Harvey O, Edwards Lisa D, et al. 2010. "Characterisation of COPD heterogeneity in the ECLIPSE cohort." Respiratory research 11 doi:10.1186/1465-9921-11-122

2009

MacNee William, Tuder Rubin M 2009. "New paradigms in the pathogenesis of chronic obstructive pulmonary disease I." Proceedings of the American Thoracic Society 6 (6) doi:10.1513/pats.200905-027DS
MacNee William 2009. "Accelerated lung aging: a novel pathogenic mechanism of chronic obstructive pulmonary disease (COPD)." Biochemical Society transactions 37 (Pt 4) doi:10.1042/BST0370819
Mills Nicholas L, Donaldson Ken, Hadoke Paddy W, Boon Nicholas A, MacNee William, et al. 2009. "Adverse cardiovascular effects of air pollution." Nature clinical practice. Cardiovascular medicine 6 (1) doi:10.1038/ncpcardio1399
Behr Jürgen, Demedts Maurits, Buhl Roland, Costabel Ulrich, Dekhuijzen Richard P N, et al. 2009. "Lung function in idiopathic pulmonary fibrosis--extended analyses of the IFIGENIA trial." Respiratory research 10 doi:10.1186/1465-9921-10-101

2008

Mills Nicholas L, Robinson Simon D, Fokkens Paul H B, Leseman Daan L A C, Miller Mark R, et al. 2008. "Exposure to concentrated ambient particles does not affect vascular function in patients with coronary heart disease." Environmental health perspectives 116 (6) doi:10.1289/ehp.11016
Bathoorn Erik, Kerstjens Huib, Postma Dirkje, Timens Wim, MacNee William 2008. "Airways inflammation and treatment during acute exacerbations of COPD." International journal of chronic obstructive pulmonary disease 3 (2) doi:

2007

Monteiller Claire, Tran Lang, MacNee William, Faux Steve, Jones Alan, et al. 2007. "The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: the role of surface area." Occupational and environmental medicine 64 (9) doi:10.1136/oem.2005.024802

2006

Roghanian Ali, Drost Ellen M, MacNee William, Howie Sarah E M, Sallenave Jean-Michel 2006. "Inflammatory lung secretions inhibit dendritic cell maturation and function via neutrophil elastase." American journal of respiratory and critical care medicine 174 (11) doi:10.1164/rccm.200605-632OC
Morrison Douglas, Rahman Irfan, MacNee William 2006. "Permeability, inflammation and oxidant status in airspace epithelium exposed to ozone." Respiratory medicine 100 (12) doi:10.1016/j.rmed.2005.10.005
Szulakowski Patryk, Crowther Ann J L, Jiménez Luis A, Donaldson Kenneth, Mayer Ruth, et al. 2006. "The effect of smoking on the transcriptional regulation of lung inflammation in patients with chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 174 (1) doi:10.1164/rccm.200505-725OC
Marwick John A, Stevenson Christopher S, Giddings June, MacNee William, Butler Keith, et al. 2006. "Cigarette smoke disrupts VEGF165-VEGFR-2 receptor signaling complex in rat lungs and patients with COPD: morphological impact of VEGFR-2 inhibition." American journal of physiology. Lung cellular and molecular physiology 290 (5) doi:10.1152/ajplung.00116.2005
Szulakowski Patryk, Mróz Robert M, Pierzchała Władysław, Chyczewska Elzbieta, MacNee William 2006. "[Pathogenesis of chronic obstructive pulmonary disease. Molecular mechanisms (part II)]." Wiadomości lekarskie (Warsaw, Poland : 1960) 59 (3-4) doi:
Chappell Sally, Daly Leslie, Morgan Kevin, Guetta Baranes Tamar, Roca Josep, et al. 2006. "Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease." Human mutation 27 (1) doi:10.1002/humu.20275
Mróz Robert M, Szulakowski Patryk, Pierzchala Wliadysław, Chyczewska Elzbieta, MacNee William 2006. "[Pathogenesis of chronic obstructive pulmonary disease. Cellular mechanisms (part I)]." Wiadomości lekarskie (Warsaw, Poland : 1960) 59 (1-2) doi:

2005

Mills Nicholas L, Törnqvist Håkan, Robinson Simon D, Gonzalez Manuel, Darnley Kareen, et al. 2005. "Diesel exhaust inhalation causes vascular dysfunction and impaired endogenous fibrinolysis." Circulation 112 (25) doi:10.1161/CIRCULATIONAHA.105.588962
MacNee William 2005. "Oxidants and COPD." Current drug targets. Inflammation and allergy 4 (6) doi:
Demedts Maurits, Behr Juergen, Buhl Roland, Costabel Ulrich, Dekhuijzen Richard, et al. 2005. "High-dose acetylcysteine in idiopathic pulmonary fibrosis." The New England journal of medicine 353 (21) doi:10.1056/NEJMoa042976
Donaldson Ken, Tran Lang, Jimenez Luis Albert, Duffin Rodger, Newby David E, et al. 2005. "Combustion-derived nanoparticles: a review of their toxicology following inhalation exposure." Particle and fibre toxicology 2 doi:10.1186/1743-8977-2-10
Donaldson Ken, Mills Nicholas, MacNee William, Robinson Simon, Newby David 2005. "Role of inflammation in cardiopulmonary health effects of PM." Toxicology and applied pharmacology 207 (2 Suppl) doi:10.1016/j.taap.2005.02.020
Echazarreta Andrés L, Rahman Irfan, Peinado Victor, Barberà Joan Albert, Roca Josep, et al. 2005. "Lack of systemic oxidative stress during PAF challenge in mild asthma." Respiratory medicine 99 (5) doi:10.1016/j.rmed.2004.10.013
MacNee William 2005. "Pathogenesis of chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 2 (4) doi:10.1513/pats.200504-045SR
MacNee William 2005. "Pulmonary and systemic oxidant/antioxidant imbalance in chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 2 (1) doi:10.1513/pats.200411-056SF

2004

Chappell Sally, Guetta-Baranés Tamar, Batowski Kathryn, Yiannakis Eftihia, Morgan Kevin, et al. 2004. "Haplotypes of the alpha-1 antitrypsin gene in healthy controls and Z deficiency patients." Human mutation 24 (6) doi:10.1002/humu.9294
Antonicelli Frank, Brown David, Parmentier Maryline, Drost Ellen M, Hirani Nik, et al. 2004. "Regulation of LPS-mediated inflammation in vivo and in vitro by the thiol antioxidant Nacystelyn." American journal of physiology. Lung cellular and molecular physiology 286 (6) doi:10.1152/ajplung.00329.2003
Noguera Aina, Sala Ernest, Pons Antonia R, Iglesias Julio, MacNee William, Agustí Alvar G N 2004. "Expression of adhesion molecules during apoptosis of circulating neutrophils in COPD." Chest 125 (5) doi:
McNeilly Jane D, Heal Mathew R, Beverland Iain J, Howe Alan, Gibson Mark D, et al. 2004. "Soluble transition metals cause the pro-inflammatory effects of welding fumes in vitro." Toxicology and applied pharmacology 196 (1) doi:10.1016/j.taap.2003.11.021
Gilmour Peter S, Ziesenis Axel, Morrison E Rona, Vickers Mark A, Drost Ellen M, et al. 2004. "Pulmonary and systemic effects of short-term inhalation exposure to ultrafine carbon black particles." Toxicology and applied pharmacology 195 (1) doi:10.1016/j.taap.2003.10.003

2003

Wickenden Julie A, Clarke Murray C H, Rossi Adriano G, Rahman Irfan, Faux Stephen P, et al. 2003. "Cigarette smoke prevents apoptosis through inhibition of caspase activation and induces necrosis." American journal of respiratory cell and molecular biology 29 (5) doi:10.1165/rcmb.2002-0235OC
Donaldson Ken, Stone Vicki, Borm Paul J A, Jimenez Luis A, Gilmour Peter S, et al. 2003. "Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10)." Free radical biology & medicine 34 (11) doi:
Gilmour Peter S, Rahman Irfan, Donaldson Kenneth, MacNee William 2003. "Histone acetylation regulates epithelial IL-8 release mediated by oxidative stress from environmental particles." American journal of physiology. Lung cellular and molecular physiology 284 (3) doi:10.1152/ajplung.00277.2002
Kim Huijung, Liu Xiangde, Kobayashi Tetsu, Kohyama Tadashi, Wen Fu-Qiang, et al. 2003. "Ultrafine carbon black particles inhibit human lung fibroblast-mediated collagen gel contraction." American journal of respiratory cell and molecular biology 28 (1) doi:10.1165/rcmb.4796

2002

Rahman Irfan, van Schadewijk Annemarie A M, Crowther Ann J L, Hiemstra Pieter S, Stolk Jan, et al. 2002. "4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 166 (4) doi:10.1164/rccm.2110101
Kim Hui Jung, Liu Xiangde, Wang Hangjun, Kohyama Tadashi, Kobayashi Tetsu, et al. 2002. "Glutathione prevents inhibition of fibroblast-mediated collagen gel contraction by cigarette smoke." American journal of physiology. Lung cellular and molecular physiology 283 (2) doi:10.1152/ajplung.00059.2002
Jardine Hazel, MacNee William, Donaldson Kenneth, Rahman Irfan 2002. "Molecular mechanism of transforming growth factor (TGF)-beta1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1." The Journal of biological chemistry 277 (24) doi:10.1074/jbc.M112145200
Antonicelli Frank, Parmentier Maryline, Drost Ellen M, Hirani Nik, Rahman Irfan, et al. 2002. "Nacystelyn inhibits oxidant-mediated interleukin-8 expression and NF-kappaB nuclear binding in alveolar epithelial cells." Free radical biology & medicine 32 (6) doi:
Drost Ellen M, MacNee William 2002. "Potential role of IL-8, platelet-activating factor and TNF-alpha in the sequestration of neutrophils in the lung: effects on neutrophil deformability, adhesion receptor expression, and chemotaxis." European journal of immunology 32 (2) doi:
Donaldson Ken, Brown David, Clouter Anna, Duffin Rodger, MacNee William, et al. 2002. "The pulmonary toxicology of ultrafine particles." Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 15 (2) doi:10.1089/089426802320282338
Rahman Irfan, Gilmour Peter S, Jimenez Luis Albert, MacNee William 2002. "Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation." Molecular and cellular biochemistry 234-235 (1-2) doi: