Huston Wilhelmina M

Top coauthors of Huston Wilhelmina M

Timms Peter (28 papers)

Hocking Jane S (8 papers)

Beagley Kenneth W (8 papers)

Allan John A (7 papers)

Tyndall Joel D A (6 papers)

List of Huston Wilhelmina M publications


Wee Bryan A, Thomas Mark, Sweeney Emma Louise, Frentiu Francesca D, Samios Melanie, et al. 2017. "A retrospective pilot study to determine whether the reproductive tract microbiota differs between women with a history of infertility and fertile women." The Australian & New Zealand journal of obstetrics & gynaecology doi:10.1111/ajo.12754
Donnelly Sheila, Huston Wilhelmina M, Johnson Michael, Tiberti Natalia, Saunders Bernadette, et al. 2017. "Targeting the master regulator mTOR: a new approach to prevent the neurological of consequences of parasitic infections?" Parasites & vectors 10 (1) doi:10.1186/s13071-017-2528-3
Agbowuro Ayodeji A, Huston Wilhelmina M, Gamble Allan B, Tyndall Joel D A 2017. "Proteases and protease inhibitors in infectious diseases." Medicinal research reviews doi:10.1002/med.21475
Burnard Delaney, Huston Wilhelmina M, Webb Jonathan K, Jelocnik Martina, Reiss Andrea, et al. 2017. "Molecular evidence of Chlamydia pecorum and arthropod-associated Chlamydiae in an expanded range of marsupials." Scientific reports 7 (1) doi:10.1038/s41598-017-13164-y
Marsh James W, Djoko Karrera Y, McEwan Alastair G, Huston Wilhelmina M 2017. "Copper(II)-bis(thiosemicarbazonato) complexes as anti-chlamydial agents." Pathogens and disease 75 (7) doi:10.1093/femspd/ftx084
Marsh James W, Ong Vanissa A, Lott William B, Timms Peter, Tyndall Joel DA, Huston Wilhelmina M 2017. "CtHtrA: the lynchpin of the chlamydial surface and a promising therapeutic target." Future microbiology 12 doi:10.2217/fmb-2017-0017
Kerr Markus C, Gomez Guillermo A, Ferguson Charles, Tanzer Maria C, Murphy James M, et al. 2017. "Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis." Nature communications 8 doi:10.1038/ncomms14729
Paul Blessy, Kim Hyun Sung, Kerr Markus C, Huston Wilhelmina M, Teasdale Rohan D, Collins Brett M 2017. "Structural basis for the hijacking of endosomal sorting nexin proteins by Chlamydia trachomatis." eLife 6 doi:10.7554/eLife.22311
Gupta Vivek Kumar, Waugh Courtney Alice, Ziklo Noa, Huston Wilhelmina M, Hocking Jane S, Timms Peter 2017. "Systemic antibody response to Chlamydia Trachomatis infection in patients either infected or reinfected with different Chlamydia serovars." Indian journal of medical microbiology 35 (3) doi:10.4103/ijmm.IJMM_17_1
Vodstrcil Lenka A, Rupasinghe Thusitha W T, Kong Fabian Y S, Tull Dedreia, Worthington Karen, et al. 2017. "Measurement of tissue azithromycin levels in self-collected vaginal swabs post treatment using liquid chromatography and tandem mass spectrometry (LC-MS/MS)." PloS one 12 (5) doi:10.1371/journal.pone.0177615


Ziklo Noa, Huston Wilhelmina M, Taing Kuong, Katouli Mohammad, Timms Peter 2016. "In vitro rescue of genital strains of Chlamydia trachomatis from interferon-γ and tryptophan depletion with indole-positive, but not indole-negative Prevotella spp." BMC microbiology 16 (1) doi:10.1186/s12866-016-0903-4
Ziklo Noa, Huston Wilhelmina M, Hocking Jane S, Timms Peter 2016. "Chlamydia trachomatis Genital Tract Infections: When Host Immune Response and the Microbiome Collide." Trends in microbiology doi:10.1016/j.tim.2016.05.007
Zhu Yan, Pham Thi Huong, Nhiep Thi Hanh Nguyen, Vu Ngoc Minh Thu, Marcellin Esteban, et al. 2016. "Cyclic-di-AMP synthesis by the diadenylate cyclase CdaA is modulated by the peptidoglycan biosynthesis enzyme GlmM in Lactococcus lactis." Molecular microbiology 99 (6) doi:10.1111/mmi.13281
Menon Shruti, Alexander Kimberly, Timms Peter, Allan John A, Huston Wilhelmina M 2016. "CXCL10, CXCL11, HLA-A and IL-1β are induced in peripheral blood mononuclear cells from women with Chlamydia trachomatis related infertility." Pathogens and disease 74 (1) doi:10.1093/femspd/ftv099
Lawrence Amba, Fraser Tamieka, Gillett Amber, Tyndall Joel D A, Timms Peter, et al. 2016. "Chlamydia Serine Protease Inhibitor, targeting HtrA, as a New Treatment for Koala Chlamydia infection." Scientific reports 6 doi:10.1038/srep31466
Christensen Signe, Grøftehauge Morten K, Byriel Karl, Huston Wilhelmina M, Furlong Emily, et al. 2016. "Structural and Biochemical Characterization of Chlamydia trachomatis DsbA Reveals a Cysteine-Rich and Weakly Oxidising Oxidoreductase." PloS one 11 (12) doi:10.1371/journal.pone.0168485


Vodstrcil Lenka A, McIver Ruthy, Huston Wilhelmina M, Tabrizi Sepehr N, Timms Peter, Hocking Jane S 2015. "The Epidemiology of Chlamydia trachomatis Organism Load During Genital Infection: A Systematic Review." The Journal of infectious diseases 211 (10) doi:10.1093/infdis/jiu670
Kong Fabian Yuh Shiong, Tabrizi Sepehr N, Fairley Christopher Kincaid, Vodstrcil Lenka A, Huston Wilhelmina M, et al. 2015. "The efficacy of azithromycin and doxycycline for the treatment of rectal chlamydia infection: a systematic review and meta-analysis." The Journal of antimicrobial chemotherapy 70 (5) doi:10.1093/jac/dku574
Hocking Jane S, Kong Fabian Y S, Timms Peter, Huston Wilhelmina M, Tabrizi Sepehr N 2015. "Treatment of rectal chlamydia infection may be more complicated than we originally thought." The Journal of antimicrobial chemotherapy 70 (4) doi:10.1093/jac/dku493
Chacko Anu, Beagley Kenneth W, Timms Peter, Huston Wilhelmina M 2015. "Human Chlamydia pneumoniae isolates demonstrate ability to recover infectivity following penicillin treatment whereas animal isolates do not." FEMS microbiology letters 362 (6) doi:10.1093/femsle/fnv015
Marsh James W, Wee Bryan A, Tyndall Joel D A, Lott William B, Bastidas Robert J, et al. 2015. "A Chlamydia trachomatis strain with a chemically generated amino acid substitution (P370L) in the cthtrA gene shows reduced elementary body production." BMC microbiology 15 doi:10.1186/s12866-015-0533-2
Ong Vanissa A, Lawrence Amba, Timms Peter, Vodstrcil Lenka A, Tabrizi Sepehr N, et al. 2015. "In vitro susceptibility of recent Chlamydia trachomatis clinical isolates to the CtHtrA inhibitor JO146." Microbes and infection / Institut Pasteur 17 (11-12) doi:10.1016/j.micinf.2015.09.004


Chacko Anu, Barker Christopher J, Beagley Kenneth W, Hodson Mark P, Plan Manuel R, et al. 2014. "Increased sensitivity to tryptophan bioavailability is a positive adaptation by the human strains of Chlamydia pneumoniae." Molecular microbiology 93 (4) doi:10.1111/mmi.12701
Huston Wilhelmina M, Barker Christopher J, Chacko Anu, Timms Peter 2014. "Evolution to a chronic disease niche correlates with increased sensitivity to tryptophan availability for the obligate intracellular bacterium Chlamydia pneumoniae." Journal of bacteriology 196 (11) doi:10.1128/JB.01476-14


Gloeckl Sarina, Ong Vanissa A, Patel Pooja, Tyndall Joel D A, Timms Peter, et al. 2013. "Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatis." Molecular microbiology 89 (4) doi:10.1111/mmi.12306
Carey Alison J, Huston Wilhelmina M, Cunningham Kelly A, Hafner Louise M, Timms Peter, Beagley Kenneth W 2013. "Characterization of in vitro chlamydia muridarum persistence and utilization in an in vivo mouse model of chlamydia vaccine." American journal of reproductive immunology (New York, N.Y. : 1989) 69 (5) doi:10.1111/aji.12093
Ong Vanissa A, Marsh James W, Lawrence Amba, Allan John A, Timms Peter, Huston Wilhelmina M 2013. "The protease inhibitor JO146 demonstrates a critical role for CtHtrA for Chlamydia trachomatis reversion from penicillin persistence." Frontiers in cellular and infection microbiology 3 doi:10.3389/fcimb.2013.00100
Hocking Jane S, Vodstrcil Lenka A, Huston Wilhelmina M, Timms Peter, Chen Marcus Y, et al. 2013. "A cohort study of Chlamydia trachomatis treatment failure in women: a study protocol." BMC infectious diseases 13 doi:10.1186/1471-2334-13-379
Stansfield Scott H, Patel Pooja, Debattista Joseph, Armitage Charles W, Cunningham Kelly, et al. 2013. "Proof of concept: A bioinformatic and serological screening method for identifying new peptide antigens for Chlamydia trachomatis related sequelae in women." Results in immunology 3 doi:10.1016/j.rinim.2013.05.001
Cunningham Kelly, Stansfield Scott H, Patel Pooja, Menon Shruti, Kienzle Vivian, et al. 2013. "The IL-6 response to Chlamydia from primary reproductive epithelial cells is highly variable and may be involved in differential susceptibility to the immunopathological consequences of chlamydial infection." BMC immunology 14 doi:10.1186/1471-2172-14-50


Gloeckl Sarina, Tyndall Joel D A, Stansfield Scott H, Timms Peter, Huston Wilhelmina M 2012. "the active site residue V266 of Chlamydial HtrA is critical for substrate binding during both in vitro and in vivo conditions." Journal of molecular microbiology and biotechnology 22 (1) doi:10.1159/000336312
Huston Wilhelmina M, Harvie Marina, Mittal Aruna, Timms Peter, Beagley Kenneth W 2012. "Vaccination to protect against infection of the female reproductive tract." Expert review of clinical immunology 8 (1) doi:10.1586/eci.11.80


Huston Wilhelmina M, Gloeckl Sarina, de Boer Leonore, Beagley Kenneth W, Timms Peter 2011. "Apoptosis is induced in Chlamydia trachomatis-infected HEp-2 cells by the addition of a combination innate immune activation compounds and the inhibitor wedelolactone." American journal of reproductive immunology (New York, N.Y. : 1989) 65 (5) doi:10.1111/j.1600-0897.2010.00936.x
Waugh Courtney A, Huston Wilhelmina M, Noad Michael J, Bengtson Nash Susan 2011. "Cytochrome P450 isozyme protein verified in the skin of southern hemisphere humpback whales (Megaptera novaeangliae): implications for biochemical biomarker assessment." Marine pollution bulletin 62 (4) doi:10.1016/j.marpolbul.2011.01.007
Huston Wilhelmina M, Tyndall Joel D A, Lott William B, Stansfield Scott H, Timms Peter 2011. "Unique residues involved in activation of the multitasking protease/chaperone HtrA from Chlamydia trachomatis." PloS one 6 (9) doi:10.1371/journal.pone.0024547


Huston Wilhelmina M, Armitage Charles W, Lawrence Amba, Gloeckl Sarina, Bell Steven J, et al. 2010. "HtrA, RseP, and Tsp proteins do not elicit a pathology-related serum IgG response during sexually transmitted infection with Chlamydia trachomatis." Journal of reproductive immunology 85 (2) doi:10.1016/j.jri.2010.02.007
Huston Wilhelmina M 2010. "Bacterial proteases from the intracellular vacuole niche; protease conservation and adaptation for pathogenic advantage." FEMS immunology and medical microbiology 59 (1) doi:10.1111/j.1574-695X.2010.00672.x


Beagley Kenneth W, Huston Wilhelmina M, Hansbro Philip M, Timms Peter 2009. "Chlamydial infection of immune cells: altered function and implications for disease." Critical reviews in immunology 29 (4) doi:


Tan Yu Pei, Giffard Philip M, Barry Daniel G, Huston Wilhelmina M, Turner Mark S 2008. "Random mutagenesis identifies novel genes involved in the secretion of antimicrobial, cell wall-lytic enzymes by Lactococcus lactis." Applied and environmental microbiology 74 (24) doi:10.1128/AEM.00767-08
Huston Wilhelmina M, Naylor Jennifer, Cianciotto Nicholas P, Jennings Michael P, McEwan Alastair G 2008. "Functional analysis of the multi-copper oxidase from Legionella pneumophila." Microbes and infection / Institut Pasteur 10 (5) doi:10.1016/j.micinf.2008.01.011
Huston Wilhelmina M, Theodoropoulos Christina, Mathews Sarah A, Timms Peter 2008. "Chlamydia trachomatis responds to heat shock, penicillin induced persistence, and IFN-gamma persistence by altering levels of the extracytoplasmic stress response protease HtrA." BMC microbiology 8 doi:10.1186/1471-2180-8-190
Cole Lindsay J, Huston Wilhelmina M, Moir James W B 2008. "Delivery of nitric oxide for analysis of the function of cytochrome c'." Methods in enzymology 436 doi:10.1016/S0076-6879(08)36002-9


Huston Wilhelmina M, Swedberg Joaquim E, Harris Jonathan M, Walsh Terence P, Mathews Sarah A, Timms Peter 2007. "The temperature activated HtrA protease from pathogen Chlamydia trachomatis acts as both a chaperone and protease at 37 degrees C." FEBS letters 581 (18) doi:10.1016/j.febslet.2007.06.039
Huston Wilhelmina M, Harhangi Harry R, Leech Andrew P, Butler Clive S, Jetten Mike S M, et al. 2007. "Expression and characterisation of a major c-type cytochrome encoded by gene kustc0563 from Kuenenia stuttgartiensis as a recombinant protein in Escherichia coli." Protein expression and purification 51 (1) doi:10.1016/j.pep.2006.06.026


Huston Wilhelmina M, Andrew Colin R, Servid Amy E, McKay Alison L, Leech Andrew P, et al. 2006. "Heterologous overexpression and purification of cytochrome c' from Rhodobacter capsulatus and a mutant (K42E) in the dimerization region. Mutation does not alter oligomerization but impacts the heme iron spin state and nitric oxide binding properties." Biochemistry 45 (14) doi:10.1021/bi052605j


Huston Wilhelmina M, Potter Adam J, Jennings Michael P, Rello Jordi, Hauser Alan R, McEwan Alastair G 2004. "Survey of ferroxidase expression and siderophore production in clinical isolates of Pseudomonas aeruginosa." Journal of clinical microbiology 42 (6) doi:10.1128/JCM.42.6.2806-2809.2004


Huston Wilhelmina M, Jennings Michael P, McEwan Alastair G 2002. "The multicopper oxidase of Pseudomonas aeruginosa is a ferroxidase with a central role in iron acquisition." Molecular microbiology 45 (6) doi:
Kappler Ulrike, Huston Wilhelmina M, McEwan Alastair G 2002. "Control of dimethylsulfoxide reductase expression in Rhodobacter capsulatus: the role of carbon metabolites and the response regulators DorR and RegA." Microbiology (Reading, England) 148 (Pt 2) doi: