Adcock Ian M

Top coauthors of Adcock Ian M

Barnes Peter J (84 papers)

Ito Kazuhiro (51 papers)

Chung Kian Fan (49 papers)

Caramori Gaetano (45 papers)

Mortaz Esmaeil (31 papers)

List of Adcock Ian M publications

2017

Ng Kee Kwong Francois, Nicholson Andrew G, Harrison Celeste L, Hansbro Philip M, Adcock Ian M, Chung Kian Fan 2017. "Is mitochondrial dysfunction a driving mechanism linking COPD to nonsmall cell lung carcinoma?" European respiratory review : an official journal of the European Respiratory Society 26 (146) doi:10.1183/16000617.0040-2017
Di Stefano Antonino, Sangiorgi Claudia, Gnemmi Isabella, Casolari Paolo, Brun Paola, et al. 2017. "TGF-β signalling pathways in different compartments of the lower airways of stable COPD patients." Chest doi:10.1016/j.chest.2017.12.017
Rossios Christos, Pavlidis Stelios, Gibeon David, Mumby Sharon, Durham Andrew, et al. 2017. "Impaired innate immune gene profiling in airway smooth muscle cells from chronic cough patients." Bioscience reports 37 (6) doi:10.1042/BSR20171090
Alinejad Dizaj Maryam, Mortaz Esmaeil, Mahdaviani Seyed Alireza, Mansouri Davood, Mehrian Payam, et al. 2017. "Susceptibility to mycobacterial disease due to mutations in IL-12Rβ1 in three Iranian patients." Immunogenetics doi:10.1007/s00251-017-1041-3
Mallia Patrick, Webber Jessica, Gill Simren K, Trujillo-Torralbo Maria-Belen, Calderazzo Maria Adelaide, et al. 2017. "Role of airway glucose in bacterial infections in patients with chronic obstructive pulmonary disease." The Journal of allergy and clinical immunology doi:10.1016/j.jaci.2017.10.017
Caramori Gaetano, Ruggeri Paolo, Casolari Paolo, Chung Kian Fan, Girbino Giuseppe, Adcock Ian M 2017. "Fluticasone furoate and vilanterol for the treatment of chronic obstructive pulmonary disease." Expert review of respiratory medicine 11 (12) doi:10.1080/17476348.2017.1386564
Caramori Gaetano, Ruggeri Paolo, Di Stefano Antonino, Mumby Sharon, Girbino Giuseppe, et al. 2017. "Autoimmunity and COPD: Clinical Implications." Chest doi:10.1016/j.chest.2017.10.033
Michaeloudes Charalambos, Kuo Chih-Hsi, Haji Gulam, Finch Donna K, Halayko Andrew J, et al. 2017. "Metabolic re-patterning in COPD airway smooth muscle cells." The European respiratory journal 50 (5) doi:10.1183/13993003.00202-2017
Michaeloudes Charalambos, Bhavsar Pankaj K, Mumby Sharon, Chung Kian Fan, Adcock Ian M 2017. "Dealing with Stress: Defective Metabolic Adaptation in Chronic Obstructive Pulmonary Disease Pathogenesis." Annals of the American Thoracic Society 14 (Supplement_5) doi:10.1513/AnnalsATS.201702-153AW
Hashemian Seyed Mohammadreza, Mortaz Esmaeil, Jamaati Hamidreza, Bagheri Leila, Mohajerani Seyed Amir, et al. 2017. "Budesonide facilitates weaning from mechanical ventilation in difficult-to-wean very severe COPD patients: Association with inflammatory mediators and cells." Journal of critical care 44 doi:10.1016/j.jcrc.2017.10.045
Shamaei Masoud, Mortaz Esmaeil, Pourabdollah Mihan, Garssen Johan, Tabarsi Payam, et al. 2017. "Evidence for M2 macrophages in granulomas from pulmonary sarcoidosis: a new aspect of macrophage heterogeneity." Human immunology doi:10.1016/j.humimm.2017.10.009
Haw Tatt Jhong, Starkey Malcolm R, Pavlidis Stelios, Fricker Michael, Arthurs Anya L, et al. 2017. "Toll-like receptor 2 and 4 have Opposing Roles in the Pathogenesis of Cigarette Smoke-induced Chronic Obstructive Pulmonary Disease." American journal of physiology. Lung cellular and molecular physiology doi:10.1152/ajplung.00154.2017
Li Xiang, Michaeloudes Charalambos, Zhang Yuelin, Wiegman Coen H, Adcock Ian M, et al. 2017. "Mesenchymal stem cells alleviate oxidative stress-induced mitochondrial dysfunction in the airways." The Journal of allergy and clinical immunology doi:10.1016/j.jaci.2017.08.017
Hekking Pieter-Paul, Loza Matthew J, Pavlidis Stelios, De Meulder Bertrand, Lefaudeux Diane, et al. 2017. "Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma." The European respiratory journal 50 (3) doi:10.1183/13993003.02298-2016
Mortaz Esameil, Adcock Ian M, Tabarsi Payam, Darazam Ilad Alavi, Movassaghi Masoud, et al. 2017. "Pattern recognitions receptors in immunodeficiency disorders." European journal of pharmacology 808 doi:10.1016/j.ejphar.2017.01.014
Mortaz Esmaeil, Adcock Ian M, Abedini Atefhe, Kiani Arda, Kazempour-Dizaji Mehdi, et al. 2017. "The role of pattern recognition receptors in lung sarcoidosis." European journal of pharmacology 808 doi:10.1016/j.ejphar.2017.01.020
Mortaz Esmaeil, Adcock Ian M, Jamaati Hamidreza, Khosravi Adnan, Movassaghi Masoud, et al. 2017. "Immunoglobulin Free Light Chains in the Pathogenesis of Lung Disorders." Iranian journal of allergy, asthma, and immunology 16 (4) doi:
Hekking Pieter-Paul, Loza Matt J, Pavlidis Stelios, de Meulder Bertrand, Lefaudeux Diane, et al. 2017. "Pathway discovery using transcriptomic profiles in adult-onset severe asthma." The Journal of allergy and clinical immunology doi:10.1016/j.jaci.2017.06.037
Mortaz Esmaeil, Marashian Sayed Mehran, Ghaffaripour Hosseinali, Varahram Mohammad, Mehrian Payam, et al. 2017. "A new ataxia-telangiectasia mutation in an 11-year-old female." Immunogenetics 69 (7) doi:10.1007/s00251-017-0983-9
Wang Yujie, Jia Man, Yan Xiaoyi, Cao Limin, Barnes Peter J, et al. 2017. "Increased neutrophil gelatinase-associated lipocalin (NGAL) promotes airway remodelling in chronic obstructive pulmonary disease." Clinical science (London, England : 1979) 131 (11) doi:10.1042/CS20170096
Rossios Christos, Pavlidis Stelios, Hoda Uruj, Kuo Chih-Hsi, Wiegman Coen, et al. 2017. "Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma." The Journal of allergy and clinical immunology doi:10.1016/j.jaci.2017.02.045
Bigler Jeannette, Boedigheimer Michael, Schofield James P R, Skipp Paul J, Corfield Julie, et al. 2017. "A Severe Asthma Disease Signature from Gene Expression Profiling of Peripheral Blood from U-BIOPRED Cohorts." American journal of respiratory and critical care medicine 195 (10) doi:10.1164/rccm.201604-0866OC
Alipoor Shamila D, Mortaz Esmaeil, Tabarsi Payam, Farnia Parissa, Mirsaeidi Mehdi, et al. 2017. "Bovis Bacillus Calmette-Guerin (BCG) infection induces exosomal miRNA release by human macrophages." Journal of translational medicine 15 (1) doi:10.1186/s12967-017-1205-9
Di Stefano Antonino, Ricciardolo Fabio L M, Caramori Gaetano, Adcock Ian M, Chung Kian Fan, et al. 2017. "Bronchial inflammation and bacterial load in stable COPD is associated with TLR4 overexpression." The European respiratory journal 49 (5) doi:10.1183/13993003.02006-2016
Mortaz Esmaeil, Alipoor Shamila D, Movassaghi Masoud, Varahram Mohammad, Ghorbani Jahangir, et al. 2017. "Water-pipe smoke condensate increases the internalization of Mycobacterium Bovis of type II alveolar epithelial cells (A549)." BMC pulmonary medicine 17 (1) doi:10.1186/s12890-017-0413-7
Shim Jung Min, Lee Jin S, Russell Kirsty E, Wiegman Coen H, Barnes Peter J, et al. 2017. "BET proteins are a key component of immunoglobulin gene expression." Epigenomics 9 (4) doi:10.2217/epi-2016-0147
Machin Matthew, Amaral André F S, Wielscher Matthias, Rezwan Faisal I, Imboden Medea, et al. 2017. "Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies." BMC pulmonary medicine 17 (1) doi:10.1186/s12890-017-0397-3
Langley Gillian R, Adcock Ian M, Busquet François, Crofton Kevin M, Csernok Elena, et al. 2017. "Towards a 21st-century roadmap for biomedical research and drug discovery: consensus report and recommendations." Drug discovery today 22 (2) doi:10.1016/j.drudis.2016.10.011
Kuo Chih-Hsi Scott, Pavlidis Stelios, Loza Matthew, Baribaud Fred, Rowe Anthony, et al. 2017. "T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED." The European respiratory journal 49 (2) doi:10.1183/13993003.02135-2016
Adcock Ian M, Mumby Sharon 2017. "Glucocorticoids." Handbook of experimental pharmacology 237 doi:10.1007/164_2016_98
Jamaati Hamidreza, Mortaz Esmaeil, Pajouhi Zeinab, Folkerts Gert, Movassaghi Mehrnaz, et al. 2017. "Nitric Oxide in the Pathogenesis and Treatment of Tuberculosis." Frontiers in microbiology 8 doi:10.3389/fmicb.2017.02008

2016

Adcock Ian M, Mortaz Esmaeil, Alipoor Shamila D, Garssen Johan, Akbar Velayati Ali 2016. "In vitro effects of water-pipe smoke condensate on the endocytic activity of Type II alveolar epithelial cells (A549) with bacillus Calmette-Guérin." International journal of mycobacteriology 5 Suppl 1 doi:10.1016/j.ijmyco.2016.09.036
Mortaz Esmaeil, Alipoor Shamila D, Tabarsi Payam, Adcock Ian M, Garssen Johan, Velayati Ali Akbar 2016. "The analysis of exosomal micro-RNAs in peripheral blood mononuclear cell-derived macrophages after infection with bacillus Calmette-Guérin by RNA sequencing." International journal of mycobacteriology 5 Suppl 1 doi:10.1016/j.ijmyco.2016.09.045
Tabarsi Payam, Marjani Majid, Moniri Afshin, Farnia Parissa, Dizaji Mehdi Kazempour, et al. 2016. "Investigation of urine lipoarabinomannan in human immunodeficiency virus patients with or without coinfection with Tuberculosis in Iran." International journal of mycobacteriology 5 Suppl 1 doi:10.1016/j.ijmyco.2016.11.005
Mortaz Esmaeil, Masjedi Mohammad Reza, Abedini Atefeh, Matroodi Soheila, Kiani Arda, et al. 2016. "Common features of tuberculosis and sarcoidosis." International journal of mycobacteriology 5 Suppl 1 doi:10.1016/j.ijmyco.2016.09.031
Lefaudeux Diane, De Meulder Bertrand, Loza Matthew J, Peffer Nancy, Rowe Anthony, et al. 2016. "U-BIOPRED clinical adult asthma clusters linked to a subset of sputum -omics." The Journal of allergy and clinical immunology doi:10.1016/j.jaci.2016.08.048
Athari Seyyed Shamsadin, Pourpak Zahra, Folkerts Gert, Garssen Johan, Moin Mostafa, et al. 2016. "Conjugated Alpha-Alumina nanoparticle with vasoactive intestinal peptide as a Nano-drug in treatment of allergic asthma in mice." European journal of pharmacology doi:10.1016/j.ejphar.2016.10.014
Jones Bernadette, Donovan Chantal, Liu Gang, Gomez Henry M, Chimankar Vrushali, et al. 2016. "Animal models of COPD: What do they tell us?" Respirology (Carlton, Vic.) doi:10.1111/resp.12908
Ravanetti Lara, Dijkhuis Annemiek, Sabogal Pineros Yanaika S, Bal Suzanne M, Dierdorp Barbara S, et al. 2016. "An early innate response underlies severe influenza-induced exacerbations of asthma in a novel steroid-insensitive and anti-IL-5 responsive mouse model." Allergy doi:10.1111/all.13057
Alipoor Shamila D, Adcock Ian M, Garssen Johan, Mortaz Esmaeil, Varahram Mohammad, et al. 2016. "The roles of miRNAs as potential biomarkers in lung diseases." European journal of pharmacology doi:10.1016/j.ejphar.2016.09.015
Kuo Chih-Hsi Scott, Pavlidis Stelios, Loza Matthew, Baribaud Fred, Rowe Anthony, et al. 2016. "A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED." American journal of respiratory and critical care medicine doi:10.1164/rccm.201512-2452OC
Mumby Sharon, Gambaryan Natalia, Meng Chao, Perros Frederic, Humbert Marc, et al. 2016. "Bromodomain and extra-terminal protein mimic JQ1 decreases inflammation in human vascular endothelial cells: Implications for pulmonary arterial hypertension." Respirology (Carlton, Vic.) doi:10.1111/resp.12872
Mortaz Esmaeil, Rezayat Fatemeh, Amani Davar, Kiani Arda, Garssen Johan, et al. 2016. "The Roles of T Helper 1, T Helper 17 and Regulatory T Cells in the Pathogenesis of Sarcoidosis." Iranian journal of allergy, asthma, and immunology 15 (4) doi:
Austin Philip J, Tsitsiou Eleni, Boardman Charlotte, Jones Simon W, Lindsay Mark A, et al. 2016. "Transcriptional profiling identifies the long noncoding RNA plasmacytoma variant translocation (PVT1) as a novel regulator of the asthmatic phenotype in human airway smooth muscle." The Journal of allergy and clinical immunology doi:10.1016/j.jaci.2016.06.014
Kim Richard Y, Horvat Jay C, Pinkerton James W, Starkey Malcolm R, Essilfie Ama T, et al. 2016. "MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2." The Journal of allergy and clinical immunology doi:10.1016/j.jaci.2016.04.038
Aryanpur Mahshid, Mortaz Esmaeil, Masjedi Mohammad Reza, Tabarsi Payam, Garssen Johan, et al. 2016. "Reduced Phagocytic Capacity of Blood Monocyte/Macrophages in Tuberculosis Patients Is Further Reduced by Smoking." Iranian journal of allergy, asthma, and immunology 15 (3) doi:
Lee Jin, Machin Matthew, Russell Kirsty E, Pavlidis Stelios, Zhu Jie, et al. 2016. "Corticosteroid modulation of immunoglobulin expression and B-cell function in COPD." FASEB journal : official publication of the Federation of American Societies for Experimental Biology doi:10.1096/fj.201500135
Durham Andrew L, Caramori Gaetano, Chung Kian F, Adcock Ian M 2016. "Targeted anti-inflammatory therapeutics in asthma and chronic obstructive lung disease." Translational research : the journal of laboratory and clinical medicine 167 (1) doi:10.1016/j.trsl.2015.08.004
Russell Kirsty E, Chung Kian Fan, Clarke Colin J, Durham Andrew L, Mallia Patrick, et al. 2016. "The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD." PloS one 11 (1) doi:10.1371/journal.pone.0146102
Footitt Joseph, Mallia Patrick, Durham Andrew L, Ho W Eugene, Trujillo-Torralbo Maria-Belen, et al. 2016. "Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD." Chest 149 (1) doi:10.1378/chest.14-2637
Mortaz Esmaeil, Tabarsi Payam, Mansouri Davod, Khosravi Adnan, Garssen Johan, et al. 2016. "Cancers Related to Immunodeficiencies: Update and Perspectives." Frontiers in immunology 7 doi:10.3389/fimmu.2016.00365
Alipoor Shamila D, Mortaz Esmaeil, Garssen Johan, Movassaghi Masoud, Mirsaeidi Mehdi, Adcock Ian M 2016. "Exosomes and Exosomal miRNA in Respiratory Diseases." Mediators of inflammation 2016 doi:10.1155/2016/5628404
Poletti Donatella, Iannini Valeria, Casolari Paolo, Contoli Marco, Papi Alberto, et al. 2016. "Nasal inflammation and its response to local glucocorticoid regular treatment in patients with persistent non-allergic rhinitis: a pilot study." Journal of inflammation (London, England) 13 doi:10.1186/s12950-016-0134-3

2015

Gao Wei, Yuan Cheng, Zhang Jingying, Li Lingling, Yu Like, et al. 2015. "Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury." Clinical science (London, England : 1979) 129 (12) doi:10.1042/CS20150273
Ngkelo Anta, Hoffmann Roland F, Durham Andrew L, Marwick John A, Brandenburg Simone M, et al. 2015. "Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD." American journal of physiology. Lung cellular and molecular physiology 309 (10) doi:10.1152/ajplung.00077.2015
Shaw Dominick E, Sousa Ana R, Fowler Stephen J, Fleming Louise J, Roberts Graham, et al. 2015. "Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort." The European respiratory journal 46 (5) doi:10.1183/13993003.00779-2015
Maneechotesuwan Kittipong, Wongkajornsilp Adisak, Adcock Ian M, Barnes Peter J 2015. "Simvastatin Suppresses Airway IL-17 and Upregulates IL-10 in Patients With Stable COPD." Chest 148 (5) doi:10.1378/chest.14-3138
Wiegman Coen H, Michaeloudes Charalambos, Haji Gulammehdi, Narang Priyanka, Clarke Colin J, et al. 2015. "Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease." The Journal of allergy and clinical immunology 136 (3) doi:10.1016/j.jaci.2015.01.046
Marashian Sayed Mehran, Mortaz Esmaeil, Jamaati Hamid Reza, Alavi-Moghaddam Mostafa, Kiani Arda, et al. 2015. "Role of Innate Lymphoid Cells in Lung Disease." Iranian journal of allergy, asthma, and immunology 14 (4) doi:
Gao Wei, Li Lingling, Wang Yujie, Zhang Sini, Adcock Ian M, et al. 2015. "Bronchial epithelial cells: The key effector cells in the pathogenesis of chronic obstructive pulmonary disease?" Respirology (Carlton, Vic.) 20 (5) doi:10.1111/resp.12542
Fletcher Marianne E, Boshier Piers R, Wakabayashi Kenji, Keun Hector C, Smolenski Ryszard T, et al. 2015. "Influence of glutathione-S-transferase (GST) inhibition on lung epithelial cell injury: role of oxidative stress and metabolism." American journal of physiology. Lung cellular and molecular physiology 308 (12) doi:10.1152/ajplung.00220.2014
Haghgoo Seyyed Mortaza, Allameh Abdolamir, Mortaz Esmaeil, Garssen Johan, Folkerts Gert, et al. 2015. "Pharmacogenomics and targeted therapy of cancer: Focusing on non-small cell lung cancer." European journal of pharmacology 754 doi:10.1016/j.ejphar.2015.02.029
Perry Mark M, Durham Andrew L, Austin Philip J, Adcock Ian M, Chung Kian Fan 2015. "BET bromodomains regulate transforming growth factor-β-induced proliferation and cytokine release in asthmatic airway smooth muscle." The Journal of biological chemistry 290 (14) doi:10.1074/jbc.M114.612671
Perry Mark M, Adcock Ian M, Chung Kian Fan 2015. "Role of microRNAs in allergic asthma: present and future." Current opinion in allergy and clinical immunology 15 (2) doi:10.1097/ACI.0000000000000147
Bi Hui, Zhou Ji, Wu Dandan, Gao Wei, Li Lingling, et al. 2015. "Microarray analysis of long non-coding RNAs in COPD lung tissue." Inflammation research : official journal of the European Histamine Research Society ... [et al.] 64 (2) doi:10.1007/s00011-014-0790-9
Chung Kian Fan, Adcock Ian M 2015. "Clinical phenotypes of asthma should link up with disease mechanisms." Current opinion in allergy and clinical immunology 15 (1) doi:10.1097/ACI.0000000000000134
Mercer Paul F, Abbott-Banner Katharine, Adcock Ian M, Knowles Richard G 2015. "Translational models of lung disease." Clinical science (London, England : 1979) 128 (4) doi:10.1042/CS20140373
Price Laura C, Shao Dongmin, Meng Chao, Perros Frederic, Garfield Benjamin E, et al. 2015. "Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells." Respiratory research 16 doi:10.1186/s12931-015-0262-y
Brook Peter O, Perry Mark M, Adcock Ian M, Durham Andrew L 2015. "Epigenome-modifying tools in asthma." Epigenomics 7 (6) doi:10.2217/epi.15.53
Mortaz Esmaeil, Adcock Ian M, Ricciardolo Fabio L M, Varahram Mohammad, Jamaati Hamidreza, et al. 2015. "Anti-Inflammatory Effects of Lactobacillus Rahmnosus and Bifidobacterium Breve on Cigarette Smoke Activated Human Macrophages." PloS one 10 (8) doi:10.1371/journal.pone.0136455
Vallese Davide, Ricciardolo Fabio L M, Gnemmi Isabella, Casolari Paolo, Brun Paola, et al. 2015. "Phospho-p38 MAPK expression in COPD patients and asthmatics and in challenged bronchial epithelium." Respiration; international review of thoracic diseases 89 (4) doi:10.1159/000375168
Mortaz Esmaeil, Sereshki Hale Abdoli, Abedini Atefeh, Kiani Arda, Mirsaeidi Mehdi, et al. 2015. "Association of serum TNF-α, IL-8 and free light chain with HLA-DR B alleles expression in pulmonary and extra-pulmonary sarcoidosis." Journal of inflammation (London, England) 12 doi:10.1186/s12950-015-0066-3
Mortaz Esmaeil, Adcock Ian M, Tabarsi Payam, Masjedi Mohammad Reza, Mansouri Davood, et al. 2015. "Interaction of Pattern Recognition Receptors with Mycobacterium Tuberculosis." Journal of clinical immunology 35 (1) doi:10.1007/s10875-014-0103-7

2014

Mortaz Esmaeil, Adcock Ian M, Barnes Peter J 2014. "Sarcoidosis: Role of non-tuberculosis mycobacteria and Mycobacterium tuberculosis." International journal of mycobacteriology 3 (4) doi:10.1016/j.ijmyco.2014.10.008
Mortaz Esmaeil, Masjedi Mohammad Reza, Tabarsi Payam, Pourabdollah Mihan, Adcock Ian M 2014. "Immunopathology of sarcoidosis." Iranian journal of allergy, asthma, and immunology 13 (5) doi:
Wu Dandan, Zhou Ji, Bi Hui, Li Lingling, Gao Wei, et al. 2014. "CCL11 as a potential diagnostic marker for asthma?" The Journal of asthma : official journal of the Association for the Care of Asthma 51 (8) doi:10.3109/02770903.2014.917659
Shao Dongmin, Perros Frédéric, Caramori Gaetano, Meng Chao, Dormuller Peter, et al. 2014. "Nuclear IL-33 regulates soluble ST2 receptor and IL-6 expression in primary human arterial endothelial cells and is decreased in idiopathic pulmonary arterial hypertension." Biochemical and biophysical research communications 451 (1) doi:10.1016/j.bbrc.2014.06.111
Michaeloudes Charalambos, Mercado Nicolas, Clarke Colin, Bhavsar Pankaj K, Adcock Ian M, et al. 2014. "Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression." Journal of immunology (Baltimore, Md. : 1950) 192 (10) doi:10.4049/jimmunol.1301984
Wiegman Coen H, Li Feng, Clarke Colin J, Jazrawi Elen, Kirkham Paul, et al. 2014. "A comprehensive analysis of oxidative stress in the ozone-induced lung inflammation mouse model." Clinical science (London, England : 1979) 126 (6) doi:10.1042/CS20130039
Kirkham Paul A, Whiteman Matthew, Winyard Paul G, Caramori Gaetano, Gordon Fabiana, et al. 2014. "Impact of theophylline/corticosteroid combination therapy on sputum hydrogen sulfide levels in patients with COPD." The European respiratory journal doi:10.1183/09031936.00131513
Chung Kian Fan, Wenzel Sally E, Brozek Jan L, Bush Andrew, Castro Mario, et al. 2014. "International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma." The European respiratory journal 43 (2) doi:10.1183/09031936.00202013
Perry Mark M, Baker Josie E, Gibeon David S, Adcock Ian M, Chung Kian Fan 2014. "Airway smooth muscle hyperproliferation is regulated by microRNA-221 in severe asthma." American journal of respiratory cell and molecular biology 50 (1) doi:10.1165/rcmb.2013-0067OC
Caramori Gaetano, Chung Kian Fan, Adcock Ian M 2014. "Profile of fluticasone furoate/vilanterol dry powder inhaler combination therapy as a potential treatment for COPD." International journal of chronic obstructive pulmonary disease 9 doi:10.2147/COPD.S32604
Zhu Alling, Ge Dehai, Zhang Jingying, Teng Yue, Yuan Cheng, et al. 2014. "Sputum myeloperoxidase in chronic obstructive pulmonary disease." European journal of medical research 19 doi:10.1186/2047-783X-19-12
Hashemian Seyed Mohamad Reza, Mortaz Esmaeil, Tabarsi Payam, Jamaati Hamidreza, Maghsoomi Zohreh, et al. 2014. "Elevated CXCL-8 expression in bronchoalveolar lavage correlates with disease severity in patients with acute respiratory distress syndrome resulting from tuberculosis." Journal of inflammation (London, England) 11 doi:10.1186/1476-9255-11-21
Barczyk Adam, Pierzchala Wladyslaw, Caramori Gaetano, Wiaderkiewicz Ryszard, Kaminski Marcin, et al. 2014. "Decreased percentage of CD4(+)Foxp3(+)TGF-β(+) and increased percentage of CD4(+)IL-17(+) cells in bronchoalveolar lavage of asthmatics." Journal of inflammation (London, England) 11 doi:10.1186/1476-9255-11-22
Khan Younis M, Kirkham Paul, Barnes Peter J, Adcock Ian M 2014. "Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells." PloS one 9 (4) doi:10.1371/journal.pone.0095051
Caramori Gaetano, Adcock Ian M, Di Stefano Antonino, Chung Kian Fan 2014. "Cytokine inhibition in the treatment of COPD." International journal of chronic obstructive pulmonary disease 9 doi:10.2147/COPD.S42544
Perry Mark M, Tsitsiou Eleni, Austin Philip J, Lindsay Mark A, Gibeon David S, et al. 2014. "Role of non-coding RNAs in maintaining primary airway smooth muscle cells." Respiratory research 15 doi:10.1186/1465-9921-15-58
Kankaanranta Hannu, Ilmarinen Pinja, Zhang Xianzhi, Adcock Ian M, Lahti Aleksi, et al. 2014. "Tumour necrosis factor-α regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-κB and AP-1." PloS one 9 (2) doi:10.1371/journal.pone.0090298

2013

Chung Kian Fan, Adcock Ian M 2013. "How variability in clinical phenotypes should guide research into disease mechanisms in asthma." Annals of the American Thoracic Society 10 Suppl doi:10.1513/AnnalsATS.201304-087AW
Hakim Amir, Barnes Peter J, Adcock Ian M, Usmani Omar S 2013. "Importin-7 mediates glucocorticoid receptor nuclear import and is impaired by oxidative stress, leading to glucocorticoid insensitivity." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27 (11) doi:10.1096/fj.12-222604
Haque Rubaiyat, Hakim Amir, Moodley Thunicia, Torrego Alfonso, Essilfie-Quaye Sarah, et al. 2013. "Inhaled long-acting β2 agonists enhance glucocorticoid receptor nuclear translocation and efficacy in sputum macrophages in COPD." The Journal of allergy and clinical immunology 132 (5) doi:10.1016/j.jaci.2013.07.038
Papi Alberto, Contoli Marco, Adcock Ian M, Bellettato Cinzia, Padovani Anna, et al. 2013. "Rhinovirus infection causes steroid resistance in airway epithelium through nuclear factor κB and c-Jun N-terminal kinase activation." The Journal of allergy and clinical immunology doi:10.1016/j.jaci.2013.05.028
Durham Andrew L, McLaren Alistair, Hayes Brian P, Caramori Gaetano, Clayton Chris L, et al. 2013. "Regulation of Wnt4 in chronic obstructive pulmonary disease." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27 (6) doi:10.1096/fj.12-217083
Ngkelo Anta, Adcock Ian M 2013. "New treatments for COPD." Current opinion in pharmacology doi:10.1016/j.coph.2013.03.014
Wheelock Craig E, Goss Victoria M, Balgoma David, Nicholas Ben, Brandsma Joost, et al. 2013. "Application of 'omics technologies to biomarker discovery in inflammatory lung diseases." The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology doi:10.1183/09031936.00078812
Rastrick Joseph M D, Stevenson Christopher S, Eltom Suffwan, Grace Megan, Davies Meirion, et al. 2013. "Cigarette smoke induced airway inflammation is independent of NF-κB signalling." PloS one 8 (1) doi:10.1371/journal.pone.0054128
Mortaz Esmaeil, Adcock Ian M, Folkerts Gert, Barnes Peter J, Paul Vos Arjan, Garssen Johan 2013. "Probiotics in the management of lung diseases." Mediators of inflammation 2013 doi:10.1155/2013/751068
Zhou Lin, Yuan Cheng, Zhang Jingying, Yu Rongbin, Huang Mao, et al. 2013. "Circulating leptin concentrations in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis." Respiration; international review of thoracic diseases 86 (6) doi:10.1159/000354191
Price Laura C, Caramori Gaetano, Perros Frederic, Meng Chao, Gambaryan Natalia, et al. 2013. "Nuclear factor κ-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension." PloS one 8 (10) doi:10.1371/journal.pone.0075415

2012

Mallia Patrick, Footitt Joseph, Sotero Rosa, Jepson Annette, Contoli Marco, et al. 2012. "Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 186 (11) doi:10.1164/rccm.201205-0806OC
Kabesch Michael, Adcock Ian M 2012. "Epigenetics in asthma and COPD." Biochimie 94 (11) doi:10.1016/j.biochi.2012.07.017
Forte Giovanni, Sorrentino Rosalinda, Montinaro Antonella, Luciano Antonio, Adcock Ian M, et al. 2012. "Inhibition of CD73 improves B cell-mediated anti-tumor immunity in a mouse model of melanoma." Journal of immunology (Baltimore, Md. : 1950) 189 (5) doi:10.4049/jimmunol.1200744
Wada Hiroo, Hagiwara Shin-ichi, Saitoh Erika, Ieki Ryuji, Yamamoto Yorihiro, et al. 2012. "Up-regulation of blood arachidonate (20:4) levels in patients with chronic obstructive pulmonary disease." Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 17 (6) doi:10.3109/1354750X.2012.692393
Hakim Amir, Adcock Ian M, Usmani Omar S 2012. "Corticosteroid resistance and novel anti-inflammatory therapies in chronic obstructive pulmonary disease: current evidence and future direction." Drugs 72 (10) doi:10.2165/11634350-000000000-00000
Adcock Ian M, Caramori Gaetano, Kirkham Paul A 2012. "Strategies for improving the efficacy and therapeutic ratio of glucocorticoids." Current opinion in pharmacology 12 (3) doi:10.1016/j.coph.2012.02.006
Yao Xin, Zha Wangjian, Song Wei, He Haiyan, Huang Mao, et al. 2012. "Coordinated regulation of IL-4 and IL-13 expression in human T cells: 3C analysis for DNA looping." Biochemical and biophysical research communications 417 (3) doi:10.1016/j.bbrc.2011.12.069
Park John E S, Shao Dongmin, Upton Paul D, Desouza Patricia, Adcock Ian M, et al. 2012. "BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production." PloS one 7 (1) doi:10.1371/journal.pone.0030075
Mortaz Esmaeil, Masjedi Mohammad Reza, Allameh Abdolamir, Adcock Ian M 2012. "Inflammasome signaling in pathogenesis of lung diseases." Current pharmaceutical design 18 (16) doi:
Yuan Cheng, Zhou Lin, Cheng Jiyun, Zhang Jingying, Teng Yue, et al. 2012. "Statins as potential therapeutic drug for asthma?" Respiratory research 13 doi:10.1186/1465-9921-13-108
Tomita Katsuyuki, Caramori Gaetano, Ito Kazuhiro, Sano Hiroyuki, Lim Sam, et al. 2012. "STAT6 expression in T cells, alveolar macrophages and bronchial biopsies of normal and asthmatic subjects." Journal of inflammation (London, England) 9 doi:10.1186/1476-9255-9-5
Montinaro Antonella, Forte Giovanni, Sorrentino Rosalinda, Luciano Antonio, Palma Giuseppe, et al. 2012. "Adoptive immunotherapy with Cl-IB-MECA-treated CD8+ T cells reduces melanoma growth in mice." PloS one 7 (9) doi:10.1371/journal.pone.0045401
Mortaz Esmaeil, Adcock Ian M, Shafei Hamed, Masjedi Mohammad Reza, Folkerts Gert 2012. "Role of P2X7 Receptors in Release of IL-1β: A Possible Mediator of Pulmonary Inflammation." Tanaffos 11 (2) doi:

2011

Mercado Nicholas, To Yasuo, Kobayashi Yoshiki, Adcock Ian M, Barnes Peter J, Ito Kazuhiro 2011. "p38 mitogen-activated protein kinase-γ inhibition by long-acting β2 adrenergic agonists reversed steroid insensitivity in severe asthma." Molecular pharmacology 80 (6) doi:10.1124/mol.111.071993
Rossios Christos, To Yasuo, To Masako, Ito Misako, Barnes Peter J, et al. 2011. "Long-acting fluticasone furoate has a superior pharmacological profile to fluticasone propionate in human respiratory cells." European journal of pharmacology 670 (1) doi:10.1016/j.ejphar.2011.08.022
Durham Andrew L, Wiegman Coen, Adcock Ian M 2011. "Epigenetics of asthma." Biochimica et biophysica acta 1810 (11) doi:10.1016/j.bbagen.2011.03.006
Kirkham Paul A, Caramori Gaetano, Casolari Paolo, Papi Alberto A, Edwards Matt, et al. 2011. "Oxidative stress-induced antibodies to carbonyl-modified protein correlate with severity of chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 184 (7) doi:10.1164/rccm.201010-1605OC
Teng Yue, Sun Peili, Zhang Jingying, Yu Rongbin, Bai Jianling, et al. 2011. "Hydrogen peroxide in exhaled breath condensate in patients with asthma: a promising biomarker?" Chest 140 (1) doi:10.1378/chest.10-2816
Bockmühl Yvonne, Murgatroyd Christopher A, Kuczynska Arleta, Adcock Ian M, Almeida Osborne F X, Spengler Dietmar 2011. "Differential regulation and function of 5'-untranslated GR-exon 1 transcripts." Molecular endocrinology (Baltimore, Md.) 25 (7) doi:10.1210/me.2010-0436
Sorrentino Rosalinda, Morello Silvana, Giordano Maria Grazia, Arra Claudio, Maiolino Piera, et al. 2011. "CpG-ODN increases the release of VEGF in a mouse model of lung carcinoma." International journal of cancer. Journal international du cancer 128 (12) doi:10.1002/ijc.25626
Caramori Gaetano, Adcock Ian M, Casolari Paolo, Ito Kazuhiro, Jazrawi Elen, et al. 2011. "Unbalanced oxidant-induced DNA damage and repair in COPD: a link towards lung cancer." Thorax 66 (6) doi:10.1136/thx.2010.156448
Sorrentino Rosalinda, Morello Silvana, Forte Giovanni, Montinaro Antonella, De Vita Genoveffa, et al. 2011. "B cells contribute to the antitumor activity of CpG-oligodeoxynucleotide in a mouse model of metastatic lung carcinoma." American journal of respiratory and critical care medicine 183 (10) doi:10.1164/rccm.201010-1738OC
Morello Silvana, Sorrentino Rosalinda, Montinaro Antonella, Luciano Antonio, Maiolino Piera, et al. 2011. "NK1.1 cells and CD8 T cells mediate the antitumor activity of Cl-IB-MECA in a mouse melanoma model." Neoplasia (New York, N.Y.) 13 (4) doi:
Caramori Gaetano, Lasagna Lisa, Casalini Angelo G, Adcock Ian M, Casolari Paolo, et al. 2011. "Immune response to Mycobacterium tuberculosis infection in the parietal pleura of patients with tuberculous pleurisy." PloS one 6 (7) doi:10.1371/journal.pone.0022637
Bousquet Jean, Anto Josep M, Sterk Peter J, Adcock Ian M, Chung Kian Fan, et al. 2011. "Systems medicine and integrated care to combat chronic noncommunicable diseases." Genome medicine 3 (7) doi:10.1186/gm259
Adcock Ian M, Caramori Gaetano, Barnes Peter J 2011. "Chronic obstructive pulmonary disease and lung cancer: new molecular insights." Respiration; international review of thoracic diseases 81 (4) doi:10.1159/000324601
Mortaz Esmaeil, Masjedi Mohammad Reza, Barnes Peter J, Adcock Ian M 2011. "Epigenetics and chromatin remodeling play a role in lung disease." Tanaffos 10 (4) doi:
Tsaprouni Loukia G, Ito Kazuhiro, Powell Jonathan J, Adcock Ian M, Punchard Neville 2011. "Differential patterns of histone acetylation in inflammatory bowel diseases." Journal of inflammation (London, England) 8 (1) doi:10.1186/1476-9255-8-1

2010

Sorrentino Rosalinda, Morello Silvana, Luciano Antonio, Crother Timothy R, Maiolino Piera, et al. 2010. "Plasmacytoid dendritic cells alter the antitumor activity of CpG-oligodeoxynucleotides in a mouse model of lung carcinoma." Journal of immunology (Baltimore, Md. : 1950) 185 (8) doi:10.4049/jimmunol.1000881
To Yasuo, Ito Kazuhiro, Kizawa Yasuo, Failla Marco, Ito Misako, et al. 2010. "Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 182 (7) doi:10.1164/rccm.200906-0937OC
Durham Andrew, Chou Pai-Chien, Kirkham Paul, Adcock Ian M 2010. "Epigenetics in asthma and other inflammatory lung diseases." Epigenomics 2 (4) doi:10.2217/epi.10.27
Auffray Charles, Adcock Ian M, Chung Kian Fan, Djukanovic Ratko, Pison Christophe, Sterk Peter J 2010. "An integrative systems biology approach to understanding pulmonary diseases." Chest 137 (6) doi:10.1378/chest.09-1850
Ford Paul A, Durham Andrew L, Russell Richard E K, Gordon Fabiana, Adcock Ian M, Barnes Peter J 2010. "Treatment effects of low-dose theophylline combined with an inhaled corticosteroid in COPD." Chest 137 (6) doi:10.1378/chest.09-2363
Marwick John A, Adcock Ian M, Chung Kian Fan 2010. "Overcoming reduced glucocorticoid sensitivity in airway disease: molecular mechanisms and therapeutic approaches." Drugs 70 (8) doi:10.2165/10898520-000000000-00000
Marwick John A, Caramori Gaetano, Casolari Paolo, Mazzoni Federico, Kirkham Paul A, et al. 2010. "A role for phosphoinositol 3-kinase delta in the impairment of glucocorticoid responsiveness in patients with chronic obstructive pulmonary disease." The Journal of allergy and clinical immunology 125 (5) doi:10.1016/j.jaci.2010.02.003
Marwick John A, Chung Kian Fan, Adcock Ian M 2010. "Phosphatidylinositol 3-kinase isoforms as targets in respiratory disease." Therapeutic advances in respiratory disease 4 (1) doi:10.1177/1753465809352792
Kankaanranta Hannu, Janka-Junttila Mirkka, Ilmarinen-Salo Pinja, Ito Kazuhiro, Jalonen Ulla, et al. 2010. "Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils." Journal of inflammation (London, England) 7 doi:10.1186/1476-9255-7-9
Marwick John A, Stevenson Christopher S, Chung Kian Fan, Adcock Ian M, Kirkham Paul A 2010. "Cigarette Smoke Exposure Alters mSin3a and Mi-2alpha/beta Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function." Journal of inflammation (London, England) 7 doi:10.1186/1476-9255-7-33
Zhang Jingying, Yao Xin, Yu Rongbin, Bai Jianling, Sun Yun, et al. 2010. "Exhaled carbon monoxide in asthmatics: a meta-analysis." Respiratory research 11 doi:10.1186/1465-9921-11-50
Adcock Ian M, Marwick John, Casolari Paolo, Contoli Marco, Chung Kian Fan, et al. 2010. "Mechanisms of corticosteroid resistance in severe asthma and chronic obstructive pulmonary disease (COPD)." Current pharmaceutical design 16 (32) doi:

2009

Charron Catherine E, Chou Pai-Chien, Coutts David J C, Kumar Vaibhav, To Masako, et al. 2009. "Hypoxia-inducible factor 1alpha induces corticosteroid-insensitive inflammation via reduction of histone deacetylase-2 transcription." The Journal of biological chemistry 284 (52) doi:10.1074/jbc.M109.025387
Wort Stephen J, Ito Misako, Chou Pai-Chien, Mc Master Shaun K, Badiger Rekha, et al. 2009. "Synergistic induction of endothelin-1 by tumor necrosis factor alpha and interferon gamma is due to enhanced NF-kappaB binding and histone acetylation at specific kappaB sites." The Journal of biological chemistry 284 (36) doi:10.1074/jbc.M109.032524
Caramori Gaetano, Casolari Paolo, Di Gregorio Carmela, Saetta Marina, Baraldo Simonetta, et al. 2009. "MUC5AC expression is increased in bronchial submucosal glands of stable COPD patients." Histopathology 55 (3) doi:10.1111/j.1365-2559.2009.03377.x
Chung Kian Fan, Caramori Gaetano, Adcock Ian M 2009. "Inhaled corticosteroids as combination therapy with beta-adrenergic agonists in airways disease: present and future." European journal of clinical pharmacology 65 (9) doi:10.1007/s00228-009-0682-z
Adcock Ian M, Chou Pai-Chien, Durham Andrew, Ford Paul 2009. "Overcoming steroid unresponsiveness in airways disease." Biochemical Society transactions 37 (Pt 4) doi:10.1042/BST0370824
Osoata Grace O, Yamamura Satoshi, Ito Misako, Vuppusetty Chaitanya, Adcock Ian M, et al. 2009. "Nitration of distinct tyrosine residues causes inactivation of histone deacetylase 2." Biochemical and biophysical research communications 384 (3) doi:10.1016/j.bbrc.2009.04.128
Ho Shu-Chuan, Lee Kang-Yun, Chan Yao-Fei, Kuo Lu-Wei, Ito Kazuhiro, et al. 2009. "Neutrophil elastase represses IL-8/CXCL8 synthesis in human airway smooth muscle cells through induction of NF-kappa B repressing factor." Journal of immunology (Baltimore, Md. : 1950) 183 (1) doi:10.4049/jimmunol.0803729
Papi Alberto, Caramori Gaetano, Adcock Ian M, Barnes Peter J 2009. "Rescue treatment in asthma. More than as-needed bronchodilation." Chest 135 (6) doi:10.1378/chest.08-2536
Barnes Peter J, Adcock Ian M 2009. "Glucocorticoid resistance in inflammatory diseases." Lancet 373 (9678) doi:10.1016/S0140-6736(09)60326-3
Maneechotesuwan Kittipong, Yao Xin, Ito Kazuhiro, Jazrawi Elen, Usmani Omar S, et al. 2009. "Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease." PLoS medicine 6 (5) doi:10.1371/journal.pmed.1000076
Marwick John A, Caramori Gaetano, Stevenson Christopher S, Casolari Paolo, Jazrawi Elen, et al. 2009. "Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice." American journal of respiratory and critical care medicine 179 (7) doi:10.1164/rccm.200810-1570OC
Caramori Gaetano, Adcock Ian M, Papi Alberto 2009. "Clinical definition of COPD exacerbations and classification of their severity." Southern medical journal 102 (3) doi:10.1097/SMJ.0b013e3181836b73
Williams Alison S, Eynott Paul R, Leung Sum-Yee, Nath Puneeta, Jupp Ray, et al. 2009. "Role of cathepsin S in ozone-induced airway hyperresponsiveness and inflammation." Pulmonary pharmacology & therapeutics 22 (1) doi:10.1016/j.pupt.2008.11.002
Williams Andrew E, Larner-Svensson Hanna, Perry Mark M, Campbell Gaynor A, Herrick Sarah E, et al. 2009. "MicroRNA expression profiling in mild asthmatic human airways and effect of corticosteroid therapy." PloS one 4 (6) doi:10.1371/journal.pone.0005889

2008

Marwick John A, Wallis Gillian, Meja Koremu, Kuster Bernhard, Bouwmeester Tewis, et al. 2008. "Oxidative stress modulates theophylline effects on steroid responsiveness." Biochemical and biophysical research communications 377 (3) doi:10.1016/j.bbrc.2008.10.065
Williams Alison S, Issa Razao, Durham Andrew, Leung Sum-Yee, Kapoun Ann, et al. 2008. "Role of p38 mitogen-activated protein kinase in ozone-induced airway hyperresponsiveness and inflammation." European journal of pharmacology 600 (1-3) doi:10.1016/j.ejphar.2008.09.031
Adcock Ian M, Caramori Gaetano, Chung K Fan 2008. "New targets for drug development in asthma." Lancet 372 (9643) doi:10.1016/S0140-6736(08)61449-X
Adcock Ian M, Barnes Peter J 2008. "Molecular mechanisms of corticosteroid resistance." Chest 134 (2) doi:10.1378/chest.08-0440
Ahmad Tehireem, Barnes Peter J, Adcock Ian M 2008. "Overcoming steroid insensitivity in smoking asthmatics." Current opinion in investigational drugs (London, England : 2000) 9 (5) doi:
Adcock Ian M, Ford Paul A, Bhavsar Pank, Ahmad Tehireem, Chung Kian Fan 2008. "Steroid resistance in asthma: mechanisms and treatment options." Current allergy and asthma reports 8 (2) doi:
Bhavsar Pankaj, Ahmad Tehireem, Adcock Ian M 2008. "The role of histone deacetylases in asthma and allergic diseases." The Journal of allergy and clinical immunology 121 (3) doi:10.1016/j.jaci.2007.12.1156
Caramori Gaetano, Groneberg David, Ito Kazuhiro, Casolari Paolo, Adcock Ian M, Papi Alberto 2008. "New drugs targeting Th2 lymphocytes in asthma." Journal of occupational medicine and toxicology (London, England) 3 Suppl 1 doi:10.1186/1745-6673-3-S1-S6

2007

Adcock Ian M, Tsaprouni Loukia, Bhavsar Pankaj, Ito Kazuhiro 2007. "Epigenetic regulation of airway inflammation." Current opinion in immunology 19 (6) doi:10.1016/j.coi.2007.07.016
Ito Kazuhiro, Charron Catherine E, Adcock Ian M 2007. "Impact of protein acetylation in inflammatory lung diseases." Pharmacology & therapeutics 116 (2) doi:10.1016/j.pharmthera.2007.06.009
Williams Alison S, Leung Sum-Yee, Nath Puneeta, Khorasani Nadia M, Bhavsar Pankaj, et al. 2007. "Role of TLR2, TLR4, and MyD88 in murine ozone-induced airway hyperresponsiveness and neutrophilia." Journal of applied physiology (Bethesda, Md. : 1985) 103 (4) doi:10.1152/japplphysiol.00172.2007
Maneechotesuwan Kittipong, Essilfie-Quaye Sarah, Kharitonov Sergei A, Adcock Ian M, Barnes Peter J 2007. "Loss of control of asthma following inhaled corticosteroid withdrawal is associated with increased sputum interleukin-8 and neutrophils." Chest 132 (1) doi:10.1378/chest.06-2982
Williams Alison S, Issa Razao, Leung Sum Yee, Nath Puneeta, Ferguson Gregory D, et al. 2007. "Attenuation of ozone-induced airway inflammation and hyper-responsiveness by c-Jun NH2 terminal kinase inhibitor SP600125." The Journal of pharmacology and experimental therapeutics 322 (1) doi:10.1124/jpet.107.121624
Issa Razao, Xie Shaoping, Khorasani Nadia, Sukkar Maria, Adcock Ian M, et al. 2007. "Corticosteroid inhibition of growth-related oncogene protein-alpha via mitogen-activated kinase phosphatase-1 in airway smooth muscle cells." Journal of immunology (Baltimore, Md. : 1950) 178 (11) doi:
Marwick John A, Ito Kazuhiro, Adcock Ian M, Kirkham Paul A 2007. "Oxidative stress and steroid resistance in asthma and COPD: pharmacological manipulation of HDAC-2 as a therapeutic strategy." Expert opinion on therapeutic targets 11 (6) doi:10.1517/14728222.11.6.745
Ito Kazuhiro, Caramori Gaetano, Adcock Ian M 2007. "Therapeutic potential of phosphatidylinositol 3-kinase inhibitors in inflammatory respiratory disease." The Journal of pharmacology and experimental therapeutics 321 (1) doi:10.1124/jpet.106.111674
Maneechotesuwan Kittipong, Xin Yao, Ito Kazuhiro, Jazrawi Elen, Lee Kang-Yun, et al. 2007. "Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3." Journal of immunology (Baltimore, Md. : 1950) 178 (4) doi:
Jones Edward, Adcock Ian M, Ahmed Bushra Y, Punchard Neville A 2007. "Modulation of LPS stimulated NF-kappaB mediated Nitric Oxide production by PKCepsilon and JAK2 in RAW macrophages." Journal of inflammation (London, England) 4 doi:10.1186/1476-9255-4-23

2006

Morello Silvana, Ito Kazuhiro, Yamamura Satoshi, Lee Kang-Yun, Jazrawi Elen, et al. 2006. "IL-1 beta and TNF-alpha regulation of the adenosine receptor (A2A) expression: differential requirement for NF-kappa B binding to the proximal promoter." Journal of immunology (Baltimore, Md. : 1950) 177 (10) doi:
Adcock Ian M 2006. "Histone deacetylase inhibitors as novel anti-inflammatory agents." Current opinion in investigational drugs (London, England : 2000) 7 (11) doi:
Vasavda Nisha, Eichholtz Thomas, Takahashi Atsushi, Affleck Karen, Matthews John G, et al. 2006. "Expression of nonmuscle cofilin-1 and steroid responsiveness in severe asthma." The Journal of allergy and clinical immunology 118 (5) doi:10.1016/j.jaci.2006.07.039
Adcock Ian M, Caramori Gaetano, Ito Kazuhiro 2006. "New insights into the molecular mechanisms of corticosteroids actions." Current drug targets 7 (6) doi:
Barczyk Adam, Pierzchała Władysław, Kon Onn M, Cosio Borja, Adcock Ian M, Barnes Peter J 2006. "Cytokine production by bronchoalveolar lavage T lymphocytes in chronic obstructive pulmonary disease." The Journal of allergy and clinical immunology 117 (6) doi:10.1016/j.jaci.2006.02.013
Adcock Ian M, Chung K Fan, Caramori Gaetano, Ito Kazuhiro 2006. "Kinase inhibitors and airway inflammation." European journal of pharmacology 533 (1-3) doi:10.1016/j.ejphar.2005.12.054
Ito Kazuhiro, Chung K Fian, Adcock Ian M 2006. "Update on glucocorticoid action and resistance." The Journal of allergy and clinical immunology 117 (3) doi:10.1016/j.jaci.2006.01.032
Ito Kazuhiro, Yamamura Satoshi, Essilfie-Quaye Sarah, Cosio Borja, Ito Misako, et al. 2006. "Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression." The Journal of experimental medicine 203 (1) doi:10.1084/jem.20050466
Caramori Gaetano, Ito Kazuhiro, Contoli Marco, Di Stefano Antonino, Johnston Sebastian L, et al. 2006. "Molecular mechanisms of respiratory virus-induced asthma and COPD exacerbations and pneumonia." Current medicinal chemistry 13 (19) doi:
Lee Kang-Yun, Ito Kazuhiro, Hayashi Ryuji, Jazrawi Elen P I, Barnes Peter J, Adcock Ian M 2006. "NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription." Journal of immunology (Baltimore, Md. : 1950) 176 (1) doi:
Adcock Ian M, Ford Paul, Ito Kazuhiro, Barnes P J 2006. "Epigenetics and airways disease." Respiratory research 7 doi:10.1186/1465-9921-7-21

2005

Adcock Ian M, Ito Kazuhiro, Barnes Peter J 2005. "Histone deacetylation: an important mechanism in inflammatory lung diseases." COPD 2 (4) doi:
Walters Matthew J, Paul-Clark Mark J, McMaster Shaun K, Ito Kazuhiro, Adcock Ian M, Mitchell Jane A 2005. "Cigarette smoke activates human monocytes by an oxidant-AP-1 signaling pathway: implications for steroid resistance." Molecular pharmacology 68 (5) doi:10.1124/mol.105.012591
Maneechotesuwan Kittipong, Essilfie-Quaye Sarah, Meah Sally, Kelly Claire, Kharitonov Sergei A, et al. 2005. "Formoterol attenuates neutrophilic airway inflammation in asthma." Chest 128 (4) doi:10.1378/chest.128.4.1936
Usmani Omar S, Ito Kazuhiro, Maneechotesuwan Kittipong, Ito Misako, Johnson Malcolm, et al. 2005. "Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy." American journal of respiratory and critical care medicine 172 (6) doi:10.1164/rccm.200408-1041OC
Sharma Rakesh, Bolger Aidan P, Rauchhaus Mathias, von Haehling Stephan, Doehner Wolfram, et al. 2005. "Cellular endotoxin desensitization in patients with severe chronic heart failure." European journal of heart failure 7 (5) doi:10.1016/j.ejheart.2004.09.014
Kerr Jonathan R, Kaushik Narendra, Fear David, Baldwin Don A, Nuwaysir Emile F, Adcock Ian M 2005. "Single-nucleotide polymorphisms associated with symptomatic infection and differential human gene expression in healthy seropositive persons each implicate the cytoskeleton, integrin signaling, and oncosuppression in the pathogenesis of human parvovirus B19 infection." The Journal of infectious diseases 192 (2) doi:10.1086/430950
Sharma Rakesh, von Haehling Stephan, Rauchhaus Mathias, Bolger Aidan P, Genth-Zotz Sabine, et al. 2005. "Whole blood endotoxin responsiveness in patients with chronic heart failure: the importance of serum lipoproteins." European journal of heart failure 7 (4) doi:10.1016/j.ejheart.2004.09.013
Wada Hiroo, Kagoshima Masahiko, Ito Kazuhiro, Barnes Peter J, Adcock Ian M 2005. "5-Azacytidine suppresses RNA polymerase II recruitment to the SLPI gene." Biochemical and biophysical research communications 331 (1) doi:10.1016/j.bbrc.2005.03.138
Ito Kazuhiro, Ito Misako, Elliott W Mark, Cosio Borja, Caramori Gaetano, et al. 2005. "Decreased histone deacetylase activity in chronic obstructive pulmonary disease." The New England journal of medicine 352 (19) doi:10.1056/NEJMoa041892
von Haehling Stephan, Genth-Zotz Sabine, Bolger Aidan P, Kalra Paul R, Kemp Michael, et al. 2005. "Effect of noradrenaline and isoproterenol on lipopolysaccharide-induced tumor necrosis factor-alpha production in whole blood from patients with chronic heart failure and the role of beta-adrenergic receptors." The American journal of cardiology 95 (7) doi:10.1016/j.amjcard.2004.12.022
Nath Puneeta, Eynott Paul, Leung Sum-Yee, Adcock Ian M, Bennett Brydon L, Chung Kian Fan 2005. "Potential role of c-Jun NH2-terminal kinase in allergic airway inflammation and remodelling: effects of SP600125." European journal of pharmacology 506 (3) doi:10.1016/j.ejphar.2004.11.040
Adcock Ian M, Cosio Borja, Tsaprouni Loukia, Barnes Peter J, Ito Kazuhiro 2005. "Redox regulation of histone deacetylases and glucocorticoid-mediated inhibition of the inflammatory response." Antioxidants & redox signaling 7 (1-2) doi:10.1089/ars.2005.7.144
Adcock Ian M, Ito Kazuhiro 2005. "Glucocorticoid pathways in chronic obstructive pulmonary disease therapy." Proceedings of the American Thoracic Society 2 (4) doi:10.1513/pats.200504-035SR

2004

Caramori Gaetano, Adcock Ian M, Ito Kazuhiro 2004. "Anti-inflammatory inhibitors of IkappaB kinase in asthma and COPD." Current opinion in investigational drugs (London, England : 2000) 5 (11) doi:
Hayashi Ryuji, Wada Hiroo, Ito Kazuhiro, Adcock Ian M 2004. "Effects of glucocorticoids on gene transcription." European journal of pharmacology 500 (1-3) doi:10.1016/j.ejphar.2004.07.011
Cosio Borja G, Tsaprouni Loukia, Ito Kazuhiro, Jazrawi Elen, Adcock Ian M, Barnes Peter J 2004. "Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages." The Journal of experimental medicine 200 (5) doi:10.1084/jem.20040416
Caramori Gaetano, Ito Kazuhiro, Adcock Ian M 2004. "Targeting Th2 cells in asthmatic airways." Current drug targets. Inflammation and allergy 3 (3) doi:
Adcock Ian M, Caramori Gaetano 2004. "Chemokine receptor inhibitors as a novel option in treatment of asthma." Current drug targets. Inflammation and allergy 3 (3) doi:
Caramori Gaetano, Ito Kazuhiro, Adcock Ian M 2004. "Transcription factors in asthma and COPD." IDrugs : the investigational drugs journal 7 (8) doi:
Cosío Borja G, Mann Buphinder, Ito Kazuhiro, Jazrawi Elen, Barnes Peter J, et al. 2004. "Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma." American journal of respiratory and critical care medicine 170 (2) doi:10.1164/rccm.200305-659OC
Eynott Paul R, Xu Li, Bennett Brydon L, Noble Alistair, Leung Sum-Yee, et al. 2004. "Effect of an inhibitor of Jun N-terminal protein kinase, SP600125, in single allergen challenge in sensitized rats." Immunology 112 (3) doi:10.1111/j.1365-2567.2004.01887.x
Adcock Ian M, Ito Kazuhiro 2004. "Steroid resistance in asthma: a major problem requiring novel solutions or a non-issue?" Current opinion in pharmacology 4 (3) doi:10.1016/j.coph.2004.02.001
Matthews John G, Ito Kazuhiro, Barnes Peter J, Adcock Ian M 2004. "Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients." The Journal of allergy and clinical immunology 113 (6) doi:10.1016/j.jaci.2004.03.018
Barnes Peter J, Ito Kazuhiro, Adcock Ian M 2004. "Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase." Lancet 363 (9410) doi:10.1016/S0140-6736(04)15650-X
Chung K Fan, Adcock Ian M 2004. "Combination therapy of long-acting beta2-adrenoceptor agonists and corticosteroids for asthma." Treatments in respiratory medicine 3 (5) doi:
Adcock Ian M, Caramori Gaetano 2004. "Kinase targets and inhibitors for the treatment of airway inflammatory diseases: the next generation of drugs for severe asthma and COPD?" BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 18 (3) doi:
Groneberg David A, Witt Heiko, Adcock Ian M, Hansen Gesine, Springer Jochen 2004. "Smads as intracellular mediators of airway inflammation." Experimental lung research 30 (3) doi:
Adcock Ian M, Ito Kaz, Barnes Peter J 2004. "Glucocorticoids: effects on gene transcription." Proceedings of the American Thoracic Society 1 (3) doi:10.1513/pats.200402-001MS

2003

Eynott Paul R, Nath Puneeta, Leung Sum-Yee, Adcock Ian M, Bennett Brydon L, Chung K Fan 2003. "Allergen-induced inflammation and airway epithelial and smooth muscle cell proliferation: role of Jun N-terminal kinase." British journal of pharmacology 140 (8) doi:10.1038/sj.bjp.0705569
Allen Maxine, Heinzmann Andrea, Noguchi Emiko, Abecasis Gonçalo, Broxholme John, et al. 2003. "Positional cloning of a novel gene influencing asthma from chromosome 2q14." Nature genetics 35 (3) doi:10.1038/ng1256
Paul-Clark Mark J, Roviezzo Fiorentina, Flower Roderick J, Cirino Giuseppe, Soldato Piero Del, et al. 2003. "Glucocorticoid receptor nitration leads to enhanced anti-inflammatory effects of novel steroid ligands." Journal of immunology (Baltimore, Md. : 1950) 171 (6) doi:
Zhang Youming, Leaves Nicholas I, Anderson Gavin G, Ponting Chris P, Broxholme John, et al. 2003. "Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma." Nature genetics 34 (2) doi:10.1038/ng1166
Adcock Ian M 2003. "Glucocorticoids: new mechanisms and future agents." Current allergy and asthma reports 3 (3) doi:
Gusterson Rosalind J, Jazrawi Elen, Adcock Ian M, Latchman David S 2003. "The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity." The Journal of biological chemistry 278 (9) doi:10.1074/jbc.M211762200
de Haij Simone, Adcock Ian M, Bakker Astrid C, Gobin Sam J P, Daha Mohamed R, van Kooten Cees 2003. "Steroid responsiveness of renal epithelial cells. Dissociation of transrepression and transactivation." The Journal of biological chemistry 278 (7) doi:10.1074/jbc.M209836200

2002

Adcock Ian M, Maneechotesuwan Kittipong, Usmani Omar 2002. "Molecular interactions between glucocorticoids and long-acting beta2-agonists." The Journal of allergy and clinical immunology 110 (6 Suppl) doi:
Fujii Yoshihiro, Tomita Katsuyuki, Sano Hiroyuki, Yamasaki Akira, Hitsuda Yutaka, et al. 2002. "Dissociation of DNA damage and mitochondrial injury caused by hydrogen peroxide in SV-40 transformed lung epithelial cells." Cancer cell international 2 (1) doi:
Eynott Paul R, Groneberg David A, Caramori Gaetano, Adcock Ian M, Donnelly Louise E, et al. 2002. "Role of nitric oxide in allergic inflammation and bronchial hyperresponsiveness." European journal of pharmacology 452 (1) doi:
Tomita Katsuyuki, Caramori Gaetano, Lim Sam, Ito Kazuhiro, Hanazawa Toyoyuki, et al. 2002. "Increased p21(CIP1/WAF1) and B cell lymphoma leukemia-x(L) expression and reduced apoptosis in alveolar macrophages from smokers." American journal of respiratory and critical care medicine 166 (5) doi:
Zhang Xianzhi, Moilanen Eeva, Adcock Ian M, Lindsay Mark A, Kankaanranta Hannu 2002. "Divergent effect of mometasone on human eosinophil and neutrophil apoptosis." Life sciences 71 (13) doi:
Bolger Aidan P, Sharma Rakesh, von Haehling Stephan, Doehner Wolfram, Oliver Brian, et al. 2002. "Effect of interleukin-10 on the production of tumor necrosis factor-alpha by peripheral blood mononuclear cells from patients with chronic heart failure." The American journal of cardiology 90 (4) doi:
Ito Kazuhiro, Caramori Gaetano, Lim Sam, Oates Tim, Chung K Fan, et al. 2002. "Expression and activity of histone deacetylases in human asthmatic airways." American journal of respiratory and critical care medicine 166 (3) doi:10.1164/rccm.2110060
Ito Kazuhiro, Lim Sam, Caramori Gaetano, Cosio Borja, Chung K Fan, et al. 2002. "A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression." Proceedings of the National Academy of Sciences of the United States of America 99 (13) doi:10.1073/pnas.132556899
Irusen Elvis, Matthews John G, Takahashi Atsushi, Barnes Peter J, Chung Kian F, Adcock Ian M 2002. "p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma." The Journal of allergy and clinical immunology 109 (4) doi:
Tomita Katsuyuki, Lim Sam, Hanazawa Toyoyuki, Usmani Omar, Stirling Rob, et al. 2002. "Attenuated production of intracellular IL-10 and IL-12 in monocytes from patients with severe asthma." Clinical immunology (Orlando, Fla.) 102 (3) doi:10.1006/clim.2001.5176
Ito Kazuhiro, Adcock Ian M 2002. "Histone acetylation and histone deacetylation." Molecular biotechnology 20 (1) doi:10.1385/MB:20:1:099