Wouters Emiel F M

Top coauthors of Wouters Emiel F M

Spruit Martijn A (105 papers)

Franssen Frits M E (64 papers)

Schols Annemie M W J (43 papers)

Rutten Erica P A (41 papers)

Janssen Daisy J A (40 papers)

List of Wouters Emiel F M publications

2016

Nakken Nienke, Janssen Daisy J A, van den Bogaart Esther H A, van Vliet Monique, de Vries Geeuwke J, et al. 2016. "Patient versus proxy-reported problematic activities of daily life in patients with COPD." Respirology (Carlton, Vic.) doi:10.1111/resp.12915
Mesquita Rafael, Franssen Frits M E, Houben-Wilke Sarah, Uszko-Lencer Nicole H M K, Vanfleteren Lowie E G W, et al. 2016. "What is the impact of impaired left ventricular ejection fraction in COPD after adjusting for confounders?" International journal of cardiology 225 doi:10.1016/j.ijcard.2016.10.016
Andrianopoulos Vasileios, Celli Bartolome R, Franssen Frits M E, Pinto-Plata Victor M, Calverley Peter M A, et al. 2016. "Determinants of exercise-induced oxygen desaturation including pulmonary emphysema in COPD: Results from the ECLIPSE study." Respiratory medicine 119 doi:10.1016/j.rmed.2016.08.023
Smid Dionne E, Franssen Frits M E, Houben-Wilke Sarah, Vanfleteren Lowie E G W, Janssen Daisy J A, et al. 2016. "Responsiveness and MCID Estimates for CAT, CCQ, and HADS in Patients With COPD Undergoing Pulmonary Rehabilitation: A Prospective Analysis." Journal of the American Medical Directors Association doi:10.1016/j.jamda.2016.08.002
Smid Dionne E, Spruit Martijn A, Houben-Wilke Sarah, Muris Jean W M, Rohde Gernot G U, et al. 2016. "Burden of COPD in patients treated in different care settings in the Netherlands." Respiratory medicine 118 doi:10.1016/j.rmed.2016.07.015
Houben-Wilke Sarah, Jörres Rudolf A, Bals Robert, Franssen Frits M E, Gläser Sven, et al. 2016. "Peripheral Artery Disease and its Clinical Relevance in Patients with COPD in the COSYCONET Study." American journal of respiratory and critical care medicine doi:10.1164/rccm.201602-0354OC
Andrianopoulos Vasileios, Vanfleteren Lowie E G W, Jarosch Inga, Gloeckl Rainer, Schneeberger Tessa, et al. 2016. "Transcutaneous carbon-dioxide partial pressure trends during six-minute walk test in patients with very severe COPD." Respiratory physiology & neurobiology doi:10.1016/j.resp.2016.08.003
Reynaert Niki L, Gopal Poornima, Rutten Erica P A, Wouters Emiel F M, Schalkwijk Casper G 2016. "Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential contributions to disease." The international journal of biochemistry & cell biology doi:10.1016/j.biocel.2016.06.016
Vanfleteren Lowie E G W, Spruit Martijn A, Wouters Emiel F M, Franssen Frits M E 2016. "Management of chronic obstructive pulmonary disease beyond the lungs." The Lancet. Respiratory medicine doi:10.1016/S2213-2600(16)00097-7
Ubags Niki D J, Stapleton Renee D, Vernooy Juanita H J, Burg Elianne, Bement Jenna, et al. 2016. "Hyperleptinemia is associated with impaired pulmonary host defense." JCI insight 1 (8) doi:10.1172/jci.insight.82101
Spruit Martijn A, Burtin Chris, De Boever Patrick, Langer Daniël, Vogiatzis Ioannis, et al. 2016. "COPD and exercise: does it make a difference?" Breathe (Sheffield, England) 12 (2) doi:10.1183/20734735.003916
Joppa Pavol, Tkacova Ruzena, Franssen Frits M E, Hanson Corrine, Rennard Stephen I, et al. 2016. "Sarcopenic Obesity, Functional Outcomes, and Systemic Inflammation in Patients With Chronic Obstructive Pulmonary Disease." Journal of the American Medical Directors Association doi:10.1016/j.jamda.2016.03.020
Karch Annika, Vogelmeier Claus, Welte Tobias, Bals Robert, Kauczor Hans-Ulrich, et al. 2016. "The German COPD cohort COSYCONET: Aims, methods and descriptive analysis of the study population at baseline." Respiratory medicine 114 doi:10.1016/j.rmed.2016.03.008
Ubags Niki D J, Burg Elianne, Antkowiak Maryellen, Wallace Aaron M, Dilli Estee, et al. 2016. "A Comparative Study of Lung Host Defense in Murine Obesity Models: Insights Into Neutrophil Function." American journal of respiratory cell and molecular biology doi:10.1165/rcmb.2016-0042OC
Perkins Timothy N, Dentener Mieke A, Stassen Frank R, Rohde Gernot G, Mossman Brooke T, et al. 2016. "Alteration of canonical and non-canonical WNT-signaling by crystalline silica in human lung epithelial cells." Toxicology and applied pharmacology doi:10.1016/j.taap.2016.04.003
Watz Henrik, Tetzlaff Kay, Wouters Emiel F M, Kirsten Anne, Magnussen Helgo, et al. 2016. "Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the WISDOM trial." The Lancet. Respiratory medicine doi:10.1016/S2213-2600(16)00100-4
Hoffman Sidra M, Qian Xi, Nolin James D, Chapman David G, Chia Shi Biao, et al. 2016. "Ablation of Glutaredoxin-1 Modulates House Dust Mite-induced Allergic Airways Disease in Mice." American journal of respiratory cell and molecular biology doi:10.1165/rcmb.2015-0401OC
Maatman Robbert C, Spruit Martijn A, van Melick Paula P, Peeters Jos P I, Rutten Erica P A, et al. 2016. "Effects of obesity on weight-bearing versus weight-supported exercise testing in patients with COPD." Respirology (Carlton, Vic.) 21 (3) doi:10.1111/resp.12700
Rabinovich Roberto A, Miller Bruce E, Wrobel Karolina, Ranjit Kareshma, Williams Michelle C, et al. 2016. "Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD." The European respiratory journal doi:10.1183/13993003.01824-2015
Nakken Nienke, Spruit Martijn A, van den Bogaart Esther H A, van Vliet Monique, de Vries Geeuwke J, et al. 2016. "Health Status and Morbidities in Resident Relatives of Patients With COPD." Journal of the American Medical Directors Association 17 (3) doi:10.1016/j.jamda.2015.12.012
Hoffman Sidra M, Nolin James D, Jones Jane T, Lahue Karolyn G, Chapman David G, et al. 2016. "Ablation of the Thiol Transferase Glutaredoxin-1 Augments Protein S-Glutathionylation and Modulates Type 2 Inflammatory Responses and IL-17 in a House Dust Mite Model of Allergic Airway Disease in Mice." Annals of the American Thoracic Society 13 Suppl 1 doi:10.1513/AnnalsATS.201510-656MG
Hobbs Brian D, Parker Margaret M, Chen Han, Lao Taotao, Hardin Megan, et al. 2016. "Exome Array Analysis Identifies A Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease." American journal of respiratory and critical care medicine doi:10.1164/rccm.201510-2053OC
Schleich Florence N, Dallinga Jan W, Henket Monique, Wouters Emiel F M, Louis Renaud, Van Schooten Frederik J 2016. "Volatile organic compounds discriminate between eosinophilic and neutrophilic inflammation in vitro." Journal of breath research 10 (1) doi:10.1088/1752-7155/10/1/016006
Rutten Erica P A, Gopal Poornima, Wouters Emiel F M, Franssen Frits M E, Hageman Geja J, et al. 2016. "Various Mechanistic Pathways Representing the Aging Process Are Altered in COPD." Chest 149 (1) doi:10.1378/chest.15-0645
Liu Wai-Yan, Meijer Kenneth, Delbressine Jeannet M, Willems Paul J, Franssen Frits M E, et al. 2016. "Reproducibility and Validity of the 6-Minute Walk Test Using the Gait Real-Time Analysis Interactive Lab in Patients with COPD and Healthy Elderly." PloS one 11 (9) doi:10.1371/journal.pone.0162444
De Blasio Francesca, Rutten Erica P A, Wouters Emiel F M, Scalfi Luca, De Blasio Francesco, et al. 2016. "Preliminary study on the assessment of visceral adipose tissue using dual-energy x-ray absorptiometry in chronic obstructive pulmonary disease." Multidisciplinary respiratory medicine 11 doi:10.1186/s40248-016-0070-3

2015

Spruit Martijn A, Augustin Ingrid M L, Vanfleteren Lowie E, Janssen Daisy J A, Gaffron Swetlana, et al. 2015. "Differential response to pulmonary rehabilitation in COPD: multidimensional profiling." The European respiratory journal 46 (6) doi:10.1183/13993003.00350-2015
Stoilkova-Hartmann Ana, Janssen Daisy J A, Franssen Frits M E, Wouters Emiel F M 2015. "Differences in change in coping styles between good responders, moderate responders and non-responders to pulmonary rehabilitation." Respiratory medicine 109 (12) doi:10.1016/j.rmed.2015.10.008
Nakken Nienke, Spruit Martijn A, Wouters Emiel F M, Schols Jos M G A, Janssen Daisy J A 2015. "Family caregiving during 1-year follow-up in individuals with advanced chronic organ failure." Scandinavian journal of caring sciences 29 (4) doi:10.1111/scs.12204
Vanhove Wiebe, Peeters Paul M, Staelens Dominiek, Schraenen Anica, Van der Goten Jan, et al. 2015. "Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease." Inflammatory bowel diseases 21 (11) doi:10.1097/MIB.0000000000000535
Spina Gabriele, Casale Pierluigi, Albert Paul S, Alison Jennifer, Garcia-Aymerich Judith, et al. 2015. "Identifying Physical Activity Profiles in COPD Patients Using Topic Models." IEEE journal of biomedical and health informatics 19 (5) doi:10.1109/JBHI.2015.2432033
Janssen Daisy J A, Wouters Emiel F M, Spruit Martijn A 2015. "Psychosocial consequences of living with breathlessness due to advanced disease." Current opinion in supportive and palliative care 9 (3) doi:10.1097/SPC.0000000000000146
Nakken Nienke, Janssen Daisy J A, van den Bogaart Esther H A, Wouters Emiel F M, Franssen Frits M E, et al. 2015. "Informal caregivers of patients with COPD: Home Sweet Home?" European respiratory review : an official journal of the European Respiratory Society 24 (137) doi:10.1183/16000617.00010114
Andrianopoulos Vasileios, Wouters Emiel F M, Pinto-Plata Victor M, Vanfleteren Lowie E G W, Bakke Per S, et al. 2015. "Prognostic value of variables derived from the six-minute walk test in patients with COPD: Results from the ECLIPSE study." Respiratory medicine 109 (9) doi:10.1016/j.rmed.2015.06.013
Vaes Anouk W, Meijer Kenneth, Delbressine Jeannet M, Wiechert Jozé, Willems Paul, et al. 2015. "Efficacy of walking aids on self-paced outdoor walking in individuals with COPD: A randomized cross-over trial." Respirology (Carlton, Vic.) 20 (6) doi:10.1111/resp.12570
van de Bool Coby, Rutten Erica P A, Franssen Frits M E, Wouters Emiel F M, Schols Annemie M W J 2015. "Antagonistic implications of sarcopenia and abdominal obesity on physical performance in COPD." The European respiratory journal 46 (2) doi:10.1183/09031936.00197314
Wilke Sarah, Spruit Martijn A, Wouters Emiel F M, Schols Jos M G A, Franssen Frits M E, Janssen Daisy J A 2015. "Determinants of 1-year changes in disease-specific health status in patients with advanced chronic obstructive pulmonary disease: A 1-year observational study." International journal of nursing practice 21 (3) doi:10.1111/ijn.12265
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar A, et al. 2015. "An official American Thoracic Society/European Respiratory Society statement: research questions in COPD." European respiratory review : an official journal of the European Respiratory Society 24 (136) doi:10.1183/16000617.00000315
Houben Carmen H M, Spruit Martijn A, Schols Jos M G A, Wouters Emiel F M, Janssen Daisy J A 2015. "Patient-Clinician Communication About End-of-Life Care in Patients With Advanced Chronic Organ Failure During One Year." Journal of pain and symptom management 49 (6) doi:10.1016/j.jpainsymman.2014.12.008
Wilke Sarah, Jones Paul W, Müllerova H, Vestbo Jørgen, Tal-Singer Ruth, et al. 2015. "One-year change in health status and subsequent outcomes in COPD." Thorax 70 (5) doi:10.1136/thoraxjnl-2014-205697
Andrianopoulos Vasileios, Holland Anne E, Singh Sally J, Franssen Frits M E, Pennings Herman-Jan, et al. 2015. "Six-minute walk distance in patients with chronic obstructive pulmonary disease: Which reference equations should we use?" Chronic respiratory disease 12 (2) doi:10.1177/1479972315575201
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar, et al. 2015. "An official American Thoracic Society/European Respiratory Society statement: research questions in COPD." The European respiratory journal 45 (4) doi:10.1183/09031936.00009015
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar, et al. 2015. "An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 191 (7) doi:10.1164/rccm.201501-0044ST
Perkins Timothy N, Peeters Paul M, Shukla Arti, Arijs Ingrid, Dragon Julie, et al. 2015. "Indications for distinct pathogenic mechanisms of asbestos and silica through gene expression profiling of the response of lung epithelial cells." Human molecular genetics 24 (5) doi:10.1093/hmg/ddu551
Rennard Stephen I, Locantore Nicholas, Delafont Bruno, Tal-Singer Ruth, Silverman Edwin K, et al. 2015. "Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis." Annals of the American Thoracic Society 12 (3) doi:10.1513/AnnalsATS.201403-125OC
Engel Monique, Nowacki Relana M E, Boden Pim, Reiss Lucy K, Uhlig Stefan, et al. 2015. "The effects of dexamethasone and oxygen in ventilated adult sheep with early phase acute respiratory distress syndrome." Lung 193 (1) doi:10.1007/s00408-014-9670-x
Stoilkova-Hartmann Ana, Janssen Daisy J A, Franssen Frits M E, Spruit Martijn A, Wouters Emiel F M 2015. "Attitudes of healthcare professionals providing pulmonary rehabilitation toward partnership in care." Heart & lung : the journal of critical care 44 (4) doi:10.1016/j.hrtlng.2015.05.003
Romme Elisabeth A P M, Geusens Piet, Lems Willem F, Rutten Erica P A, Smeenk Frank W J M, et al. 2015. "Fracture prevention in COPD patients; a clinical 5-step approach." Respiratory research 16 doi:10.1186/s12931-015-0192-8
Smid Dionne E, Wilke Sarah, Jones Paul W, Muris Jean W M, Wouters Emiel F M, et al. 2015. "Impact of cardiovascular comorbidities on COPD Assessment Test (CAT) and its responsiveness to pulmonary rehabilitation in patients with moderate to very severe COPD: protocol of the Chance study." BMJ open 5 (7) doi:10.1136/bmjopen-2014-007536
Barnes Peter J, Burney Peter G J, Silverman Edwin K, Celli Bartolome R, Vestbo Jørgen, et al. 2015. "Chronic obstructive pulmonary disease." Nature reviews. Disease primers 1 doi:10.1038/nrdp.2015.76

2014

Watz Henrik, Pitta Fabio, Rochester Carolyn L, Garcia-Aymerich Judith, ZuWallack Richard, et al. 2014. "An official European Respiratory Society statement on physical activity in COPD." The European respiratory journal 44 (6) doi:10.1183/09031936.00046814
Vaes Anouk W, Garcia-Aymerich Judith, Marott Jacob L, Benet Marta, Groenen Miriam T J, et al. 2014. "Changes in physical activity and all-cause mortality in COPD." The European respiratory journal 44 (5) doi:10.1183/09031936.00023214
Janssen Daisy J A, Müllerova Hana, Agusti Alvar, Yates Julie C, Tal-Singer Ruth, et al. 2014. "Persistent systemic inflammation and symptoms of depression among patients with COPD in the ECLIPSE cohort." Respiratory medicine 108 (11) doi:10.1016/j.rmed.2014.07.013
McDonald Merry-Lynn N, Cho Michael H, Sørheim Inga-Cecilie, Lutz Sharon M, Castaldi Peter J, et al. 2014. "Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 51 (5) doi:10.1165/rcmb.2014-0135OC
Magnussen Helgo, Disse Bernd, Rodriguez-Roisin Roberto, Kirsten Anne, Watz Henrik, et al. 2014. "Withdrawal of inhaled glucocorticoids and exacerbations of COPD." The New England journal of medicine 371 (14) doi:10.1056/NEJMoa1407154
Eurlings Irene M J, Dentener Mieke A, Mercken Evi M, de Cabo Rafael, Bracke Ken R, et al. 2014. "A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α." American journal of physiology. Lung cellular and molecular physiology 307 (7) doi:10.1152/ajplung.00116.2014
Diaz Alejandro A, Zhou Linfu, Young Tom P, McDonald Merry-Lynn, Harmouche Rola, et al. 2014. "Chest CT measures of muscle and adipose tissue in COPD: gender-based differences in content and in relationships with blood biomarkers." Academic radiology 21 (10) doi:10.1016/j.acra.2014.05.013
Faner Rosa, Tal-Singer Ruth, Riley John H, Celli Bartolomé, Vestbo Jørgen, et al. 2014. "Lessons from ECLIPSE: a review of COPD biomarkers." Thorax 69 (7) doi:10.1136/thoraxjnl-2013-204778
Houben Carmen H M, Spruit Martijn A, Groenen Miriam T J, Wouters Emiel F M, Janssen Daisy J A 2014. "Efficacy of advance care planning: a systematic review and meta-analysis." Journal of the American Medical Directors Association 15 (7) doi:10.1016/j.jamda.2014.01.008
Vanfleteren Lowie E G W, van Meerendonk Aniek M G, Franssen Frits M, Wouters Emiel F M, Mottaghy Felix M, et al. 2014. "A possible link between increased metabolic activity of fat tissue and aortic wall inflammation in subjects with COPD. A retrospective 18F-FDG-PET/CT pilot study." Respiratory medicine 108 (6) doi:10.1016/j.rmed.2014.04.001
Franssen Frits M E, Rutten Erica P A, Groenen Miriam T J, Vanfleteren Lowie E, Wouters Emiel F M, Spruit Martijn A 2014. "New reference values for body composition by bioelectrical impedance analysis in the general population: results from the UK Biobank." Journal of the American Medical Directors Association 15 (6) doi:10.1016/j.jamda.2014.03.012
Sillen Maurice J H, Franssen Frits M E, Delbressine Jeannet M L, Vaes Anouk W, Wouters Emiel F M, Spruit Martijn A 2014. "Efficacy of lower-limb muscle training modalities in severely dyspnoeic individuals with COPD and quadriceps muscle weakness: results from the DICES trial." Thorax 69 (6) doi:10.1136/thoraxjnl-2013-204388
Op den Kamp Céline M H, De Ruysscher Dirk K M, van den Heuvel Marieke, Elferink Meike, Houben Ruud M A, et al. 2014. "Early body weight loss during concurrent chemo-radiotherapy for non-small cell lung cancer." Journal of cachexia, sarcopenia and muscle 5 (2) doi:10.1007/s13539-013-0127-5
Vestbo Jørgen, Agusti Alvar, Wouters Emiel F M, Bakke Per, Calverley Peter M A, et al. 2014. "Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team." American journal of respiratory and critical care medicine 189 (9) doi:10.1164/rccm.201311-2006PP
Vanfleteren Lowie E G W, Spruit Martijn A, Groenen Miriam T J, Bruijnzeel Piet L B, Taib Ziad, et al. 2014. "Arterial stiffness in patients with COPD: the role of systemic inflammation and the effects of pulmonary rehabilitation." The European respiratory journal 43 (5) doi:10.1183/09031936.00169313
Spruit Martijn A, Pitta Fabio, Garvey Chris, ZuWallack Richard L, Roberts C Michael, et al. 2014. "Differences in content and organisational aspects of pulmonary rehabilitation programmes." The European respiratory journal 43 (5) doi:10.1183/09031936.00145613
Meis Jessie J M, Bosma Claudia B, Spruit Martijn A, Franssen Frits M E, Janssen Daisy J A, et al. 2014. "A qualitative assessment of COPD patients' experiences of pulmonary rehabilitation and guidance by healthcare professionals." Respiratory medicine 108 (3) doi:10.1016/j.rmed.2013.11.001
Cleutjens Fiona A H M, Spruit Martijn A, Ponds Rudolf W H M, Dijkstra Jeanette B, Franssen Frits M E, et al. 2014. "Cognitive functioning in obstructive lung disease: results from the United Kingdom biobank." Journal of the American Medical Directors Association 15 (3) doi:10.1016/j.jamda.2013.12.007
Janssen Daisy J A, Schols Jos M G A, Wouters Emiel F M, Spruit Martijn A 2014. "One-year stability of care dependency in patients with advanced chronic organ failure." Journal of the American Medical Directors Association 15 (2) doi:10.1016/j.jamda.2013.10.002
Ubags Niki D, Vernooy Juanita H, Burg Elianne, Hayes Catherine, Bement Jenna, et al. 2014. "The role of leptin in the development of pulmonary neutrophilia in infection and acute lung injury." Critical care medicine 42 (2) doi:10.1097/CCM.0000000000000048
Rutten Erica P A, Lenaerts Kaatje, Buurman Wim A, Wouters Emiel F M 2014. "Disturbed intestinal integrity in patients with COPD: effects of activities of daily living." Chest 145 (2) doi:10.1378/chest.13-0584
Cesario Alfredo, Auffray Charles, Agusti Alvar, Apolone Giovanni, Balling Rudi, et al. 2014. "A systems medicine clinical platform for understanding and managing non- communicable diseases." Current pharmaceutical design 20 (38) doi:
Breyer Marie-Kathrin, Spruit Martijn A, Hanson Corrine K, Franssen Frits M E, Vanfleteren Lowie E G W, et al. 2014. "Prevalence of metabolic syndrome in COPD patients and its consequences." PloS one 9 (6) doi:10.1371/journal.pone.0098013
Hanson Corrine, Rutten Erica P, Wouters Emiel F M, Rennard Stephen 2014. "Influence of diet and obesity on COPD development and outcomes." International journal of chronic obstructive pulmonary disease 9 doi:10.2147/COPD.S50111
Cleutjens Fiona A H M, Janssen Daisy J A, Ponds Rudolf W H M, Dijkstra Jeanette B, Wouters Emiel F M 2014. "COgnitive-pulmonary disease." BioMed research international 2014 doi:10.1155/2014/697825
Andrianopoulos Vasileios, Wagers Scott S, Groenen Miriam T J, Vanfleteren Lowie E, Franssen Frits M E, et al. 2014. "Characteristics and determinants of endurance cycle ergometry and six-minute walk distance in patients with COPD." BMC pulmonary medicine 14 doi:10.1186/1471-2466-14-97
Eurlings Irene M J, Dentener Mieke A, Cleutjens Jack P M, Peutz Carine J, Rohde Gernot G U, et al. 2014. "Similar matrix alterations in alveolar and small airway walls of COPD patients." BMC pulmonary medicine 14 doi:10.1186/1471-2466-14-90
Gopal Poornima, Reynaert Niki L, Scheijen Jean L J M, Schalkwijk Casper G, Franssen Frits M E, et al. 2014. "Association of plasma sRAGE, but not esRAGE with lung function impairment in COPD." Respiratory research 15 doi:10.1186/1465-9921-15-24
Sillen Maurice J H, Franssen Frits M E, Vaes Anouk W, Delbressine Jeannet M L, Wouters Emiel F M, Spruit Martijn A 2014. "Metabolic load during strength training or NMES in individuals with COPD: results from the DICES trial." BMC pulmonary medicine 14 doi:10.1186/1471-2466-14-146
Houben Carmen H M, Spruit Martijn A, Wouters Emiel F M, Janssen Daisy J A 2014. "A randomised controlled trial on the efficacy of advance care planning on the quality of end-of-life care and communication in patients with COPD: the research protocol." BMJ open 4 (1) doi:10.1136/bmjopen-2013-004465
Andrianopoulos Vasileios, Franssen Frits M E, Peeters Jos P I, Ubachs Tim J A, Bukari Halah, et al. 2014. "Exercise-induced oxygen desaturation in COPD patients without resting hypoxemia." Respiratory physiology & neurobiology 190 doi:10.1016/j.resp.2013.10.002
Cleutjens Fiona A H M, Wouters Emiel F M, Dijkstra Jeanette B, Spruit Martijn A, Franssen Frits M E, et al. 2014. "The COgnitive-Pulmonary Disease (COgnitive-PD) study: protocol of a longitudinal observational comparative study on neuropsychological functioning of patients with COPD." BMJ open 4 (3) doi:10.1136/bmjopen-2013-004495
Eurlings Irene M J, Reynaert Niki L, van den Beucken Twan, Gosker Harry R, de Theije C C, et al. 2014. "Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1α in mesenchymal transition." PloS one 9 (10) doi:10.1371/journal.pone.0107757
Nakken Nienke, Janssen Daisy J A, van den Bogaart Esther H A, Vercoulen Jan H, Wouters Emiel F M, Spruit Martijn A 2014. "An observational, longitudinal study on the home environment of people with chronic obstructive pulmonary disease: the research protocol of the Home Sweet Home study." BMJ open 4 (11) doi:10.1136/bmjopen-2014-006098

2013

Agustí Alvar, Barberà Joan A, Wouters Emiel F M, Peinado Victor I, Jeffery Peter K 2013. "Lungs, bone marrow, and adipose tissue. A network approach to the pathobiology of chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 188 (12) doi:10.1164/rccm.201308-1404PP
Stoilkova Ana, Janssen Daisy J A, Wouters Emiel F M 2013. "Educational programmes in COPD management interventions: a systematic review." Respiratory medicine 107 (11) doi:10.1016/j.rmed.2013.08.006
Cheng Donavan T, Kim Deog Kyeom, Cockayne Debra A, Belousov Anton, Bitter Hans, et al. 2013. "Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 188 (8) doi:10.1164/rccm.201302-0247OC
Spruit Martijn A, Singh Sally J, Garvey Chris, ZuWallack Richard, Nici Linda, et al. 2013. "An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation." American journal of respiratory and critical care medicine 188 (8) doi:10.1164/rccm.201309-1634ST
Spruit Martijn A, Sillen Maurice J H, Groenen Miriam T J, Wouters Emiel F M, Franssen Frits M E 2013. "New normative values for handgrip strength: results from the UK Biobank." Journal of the American Medical Directors Association 14 (10) doi:10.1016/j.jamda.2013.06.013
Vaes Anouk W, Cheung Amy, Atakhorrami Maryam, Groenen Miriam T J, Amft Oliver, et al. 2013. "Effect of 'activity monitor-based' counseling on physical activity and health-related outcomes in patients with chronic diseases: A systematic review and meta-analysis." Annals of medicine 45 (5-6) doi:10.3109/07853890.2013.810891
Romme Elisabeth A P M, Smeenk Frank W J M, Rutten Erica P A, Wouters Emiel F M 2013. "Osteoporosis in chronic obstructive pulmonary disease." Expert review of respiratory medicine 7 (4) doi:10.1586/17476348.2013.814402
Sillen Maurice J H, Franssen Frits M E, Delbressine Jeannet M L, Uszko-Lencer Nicole H M K, Vanfleteren Lowie E G W, et al. 2013. "Heterogeneity in clinical characteristics and co-morbidities in dyspneic individuals with COPD GOLD D: Findings of the DICES trial." Respiratory medicine 107 (8) doi:10.1016/j.rmed.2013.04.020
Berg Isaac, Hanson Corrine, Sayles Harlan, Romberger Debra, Nelson Amy, et al. 2013. "Vitamin D, vitamin D binding protein, lung function and structure in COPD." Respiratory medicine doi:10.1016/j.rmed.2013.05.010
Vanfleteren Lowie E G W, Kocks Janwillem W H, Stone Ian S, Breyer-Kohansal Robab, Greulich Timm, et al. 2013. "Moving from the Oslerian paradigm to the post-genomic era: are asthma and COPD outdated terms?" Thorax doi:10.1136/thoraxjnl-2013-203602
Stoilkova Ana, Wouters Emiel F M, Spruit Martijn A, Franssen Frits M E, Janssen Daisy J A 2013. "The relationship between coping styles and clinical outcomes in patients with COPD entering pulmonary rehabilitation." COPD 10 (3) doi:10.3109/15412555.2012.744389
Stoilkova Ana, Janssen Daisy J A, Franssen Frits M E, Spruit Martijn A, Wouters Emiel F M 2013. "Coping styles in patients with COPD before and after pulmonary rehabilitation." Respiratory medicine 107 (6) doi:10.1016/j.rmed.2013.03.001
Rutten Erica P A, Franssen Frits M E, Spruit Martijn A, Wouters Emiel F M 2013. "Anemia is Associated with Bone Mineral Density in Chronic Obstructive Pulmonary Disease." COPD 10 (3) doi:10.3109/15412555.2012.744390
Hanson Corrine, Rutten Erica P A, Wouters Emiel F M, Rennard Stephen 2013. "Diet and vitamin D as risk factors for lung impairment and COPD." Translational research : the journal of laboratory and clinical medicine doi:10.1016/j.trsl.2013.04.004
Mesquita Rafael, Janssen Daisy J A, Wouters Emiel F M, Schols Jos M G A, Pitta Fabio, Spruit Martijn A 2013. "Within-Day Test-Retest Reliability of the Timed Up & Go Test in Patients With Advanced Chronic Organ Failure." Archives of physical medicine and rehabilitation doi:10.1016/j.apmr.2013.03.024
Janssen Daisy J A, Spruit Martijn A, Schols Jos M G A, Wouters Emiel F M 2013. "Dynamic Preferences for Site of Death Among Patients With Advanced Chronic Obstructive Pulmonary Disease, Chronic Heart Failure, or Chronic Renal Failure." Journal of pain and symptom management doi:10.1016/j.jpainsymman.2013.01.007
Romme Elisabeth A P M, Rutten Erica P A, Geusens Piet, de Jong Joost J A, van Rietbergen Bert, et al. 2013. "Bone stiffness and failure load are related with clinical parameters in men with chronic obstructive pulmonary disease." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research doi:10.1002/jbmr.1947
Cheung Amy, Janssen Anton, Amft Oliver, Wouters Emiel F M, Spruit Martijn A 2013. "Usability of digital media in patients with COPD: a pilot study." International journal of technology assessment in health care 29 (2) doi:10.1017/S0266462313000135
Vanfleteren Lowie E G W, Spruit Martijn A, Groenen Miriam, Gaffron Swetlana, van Empel Vanessa P M, et al. 2013. "Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 187 (7) doi:10.1164/rccm.201209-1665OC
Vernooy Juanita H J, Ubags Niki D J, Brusselle Guy G, Tavernier Jan, Suratt Benjamin T, et al. 2013. "Leptin as regulator of pulmonary immune responses: Involvement in respiratory diseases." Pulmonary pharmacology & therapeutics doi:10.1016/j.pupt.2013.03.016
Janssen Daisy J A, Wouters Emiel F M, Schols Jos M G A, Spruit Martijn A 2013. "Care dependency independently predicts two-year survival in outpatients with advanced chronic organ failure." Journal of the American Medical Directors Association 14 (3) doi:10.1016/j.jamda.2012.09.022
Polkey Michael I, Spruit Martijn A, Edwards Lisa D, Watkins Michael L, Pinto-Plata Victor, et al. 2013. "Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization." American journal of respiratory and critical care medicine 187 (4) doi:10.1164/rccm.201209-1596OC
Romme Elisabeth A P M, Rutten Erica P A, Smeenk Frank W J M, Spruit Martijn A, Menheere Paul P C A, Wouters Emiel F M 2013. "Vitamin D status is associated with bone mineral density and functional exercise capacity in patients with chronic obstructive pulmonary disease." Annals of medicine 45 (1) doi:10.3109/07853890.2012.671536
Rutten Erica P A, Calverley Peter M A, Casaburi Richard, Agusti Alvar, Bakke Per, et al. 2013. "Changes in body composition in patients with chronic obstructive pulmonary disease: do they influence patient-related outcomes?" Annals of nutrition & metabolism 63 (3) doi:10.1159/000353211
Sillen Maurice J H, Franssen Frits M E, Gosker Harry R, Wouters Emiel F M, Spruit Martijn A 2013. "Metabolic and structural changes in lower-limb skeletal muscle following neuromuscular electrical stimulation: a systematic review." PloS one 8 (9) doi:10.1371/journal.pone.0069391
Peeters Paul M, Perkins Timothy N, Wouters Emiel F M, Mossman Brooke T, Reynaert Niki L 2013. "Silica induces NLRP3 inflammasome activation in human lung epithelial cells." Particle and fibre toxicology 10 doi:10.1186/1743-8977-10-3
Romme Elisabeth A P M, McAllister David A, Murchison John T, Van Beek Edwin J R, Petrides George S, et al. 2013. "Associations between COPD related manifestations: a cross-sectional study." Respiratory research 14 doi:10.1186/1465-9921-14-129
Janssen Daisy J A, Spruit Martijn A, Schols Jos M G A, van der Sande Frank M, Frenken Leon A, Wouters Emiel F M 2013. "Insight into advance care planning for patients on dialysis." Journal of pain and symptom management 45 (1) doi:10.1016/j.jpainsymman.2012.01.010

2012

Romme Elisabeth A P M, Murchison John T, Phang Kee F, Jansen Frits H, Rutten Erica P A, et al. 2012. "Bone attenuation on routine chest CT correlates with bone mineral density on DXA in patients with COPD." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 27 (11) doi:10.1002/jbmr.1678
Langen Ramon C J, Haegens Astrid, Vernooy Juanita H J, Wouters Emiel F M, de Winther Menno P J, et al. 2012. "NF-κB activation is required for the transition of pulmonary inflammation to muscle atrophy." American journal of respiratory cell and molecular biology 47 (3) doi:10.1165/rcmb.2011-0119OC
Engelen Mariëlle P K J, Rutten Erica P A, De Castro Carmen L N, Wouters Emiel F M, Schols Annemie M W J, Deutz Nicolaas E P 2012. "Casein protein results in higher prandial and exercise induced whole body protein anabolism than whey protein in chronic obstructive pulmonary disease." Metabolism: clinical and experimental 61 (9) doi:10.1016/j.metabol.2012.03.001
Breyer Marie-Kathrin, Rutten Erica P A, Locantore Nicholas W, Watkins Michael L, Miller Bruce E, Wouters Emiel F M 2012. "Dysregulated adipokine metabolism in chronic obstructive pulmonary disease." European journal of clinical investigation 42 (9) doi:10.1111/j.1365-2362.2012.02686.x
Gopal Poornima, Rutten Erica P A, Dentener Mieke A, Wouters Emiel F M, Reynaert Niki L 2012. "Decreased plasma sRAGE levels in COPD: influence of oxygen therapy." European journal of clinical investigation 42 (8) doi:10.1111/j.1365-2362.2012.02646.x
Graat-Verboom Lidwien, Smeenk Frank W J M, van den Borne Ben E E M, Spruit Martijn A, Donkers-van Rossum Astrid B, et al. 2012. "Risk factors for osteoporosis in Caucasian patients with moderate chronic obstructive pulmonary disease: a case control study." Bone 50 (6) doi:10.1016/j.bone.2012.02.638
Sillen Maurice J H, Vercoulen Jan H, van 't Hul Alex J, Klijn Peter H C, Wouters Emiel F M, et al. 2012. "Inaccuracy of estimating peak work rate from six-minute walk distance in patients with COPD." COPD 9 (3) doi:10.3109/15412555.2012.655866
Vanfleteren Lowie E G W, Franssen Frits M E, Wesseling Geertjan, Wouters Emiel F M 2012. "The prevalence of chronic obstructive pulmonary disease in Maastricht, the Netherlands." Respiratory medicine 106 (6) doi:10.1016/j.rmed.2012.01.008
Graat-Verboom Lidwien, Smeenk Frank W J M, van den Borne Ben E E M, Spruit Martijn A, Jansen Frits H, et al. 2012. "Progression of osteoporosis in patients with COPD: a 3-year follow up study." Respiratory medicine 106 (6) doi:10.1016/j.rmed.2011.12.020
Vaes Anouk W, Annegarn Janneke, Meijer Kenneth, Cuijpers Martijn W J, Franssen Frits M E, et al. 2012. "The effects of a "new" walking aid on exercise performance in patients with COPD: a randomized crossover trial." Chest 141 (5) doi:10.1378/chest.11-1076
Janssen Daisy J A, Spruit Martijn A, Schols Jos M G A, Cox Bianca, Nawrot Tim S, et al. 2012. "Predicting changes in preferences for life-sustaining treatment among patients with advanced chronic organ failure." Chest 141 (5) doi:10.1378/chest.11-1472
Janssen Daisy J A, Spruit Martijn A, Wouters Emiel F M, Schols Jos M G A 2012. "Family caregiving in advanced chronic organ failure." Journal of the American Medical Directors Association 13 (4) doi:10.1016/j.jamda.2011.04.017
Janssen Daisy J A, Spruit Martijn A, Wouters Emiel F M, Schols Jos M G A 2012. "Symptom distress in advanced chronic organ failure: disagreement among patients and family caregivers." Journal of palliative medicine 15 (4) doi:10.1089/jpm.2011.0394
Waschki Benjamin, Spruit Martijn A, Watz Henrik, Albert Paul S, Shrikrishna Dinesh, et al. 2012. "Physical activity monitoring in COPD: compliance and associations with clinical characteristics in a multicenter study." Respiratory medicine 106 (4) doi:10.1016/j.rmed.2011.10.022
Spruit Martijn A, Franssen Frits M E, Rutten Erica P A, Wagers Scott S, Wouters Emiel F M 2012. "Age-graded reductions in quadriceps muscle strength and peak aerobic capacity in COPD." Revista brasileira de fisioterapia (São Carlos (São Paulo, Brazil)) 16 (2) doi:
Spruit Martijn A, Polkey Michael I, Celli Bartolome, Edwards Lisa D, Watkins Michael L, et al. 2012. "Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease." Journal of the American Medical Directors Association 13 (3) doi:10.1016/j.jamda.2011.06.009
Annegarn Janneke, Meijer Kenneth, Passos Valeria Lima, Stute Katharina, Wiechert Jozé, et al. 2012. "Problematic activities of daily life are weakly associated with clinical characteristics in COPD." Journal of the American Medical Directors Association 13 (3) doi:10.1016/j.jamda.2011.01.002
Kuipers Ine, Bracke Ken R, Brusselle Guy G, Wouters Emiel F M, Reynaert Niki L 2012. "Smoke decreases reversible oxidations S-glutathionylation and S-nitrosylation in mice." Free radical research 46 (2) doi:10.3109/10715762.2011.647011
Janssen Daisy J A, Engelberg Ruth A, Wouters Emiel F M, Curtis J Randall 2012. "Advance care planning for patients with COPD: past, present and future." Patient education and counseling 86 (1) doi:10.1016/j.pec.2011.01.007
Perkins Timothy N, Shukla Arti, Peeters Paul M, Steinbacher Jeremy L, Landry Christopher C, et al. 2012. "Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells." Particle and fibre toxicology 9 (1) doi:10.1186/1743-8977-9-6
Vaes Anouk W, Franssen Frits M E, Meijer Kenneth, Cuijpers Martijn W J, Wouters Emiel F M, et al. 2012. "Effects of body mass index on task-related oxygen uptake and dyspnea during activities of daily life in COPD." PloS one 7 (7) doi:10.1371/journal.pone.0041078
Kuipers Ine, Bracke Ken R, Brusselle Guy G, Aesif Scott W, Krijgsman Renske, et al. 2012. "Altered cigarette smoke-induced lung inflammation due to ablation of Grx1." PloS one 7 (6) doi:10.1371/journal.pone.0038984
van den Berge Maarten, Hop Wim C J, van der Molen Thys, van Noord Jan A, Creemers Jacques P H M, et al. 2012. "Prediction and course of symptoms and lung function around an exacerbation in chronic obstructive pulmonary disease." Respiratory research 13 doi:10.1186/1465-9921-13-44
Annegarn Janneke, Spruit Martijn A, Savelberg Hans H C M, Willems Paul J B, van de Bool Coby, et al. 2012. "Differences in walking pattern during 6-min walk test between patients with COPD and healthy subjects." PloS one 7 (5) doi:10.1371/journal.pone.0037329
Al-shair Khaled, Muellerova Hana, Yorke Janelle, Rennard Stephen I, Wouters Emiel F M, et al. 2012. "Examining fatigue in COPD: development, validity and reliability of a modified version of FACIT-F scale." Health and quality of life outcomes 10 doi:10.1186/1477-7525-10-100
Wilke Sarah, Janssen Daisy J A, Wouters Emiel F M, Schols Jos M G A, Franssen Frits M E, Spruit Martijn A 2012. "Correlations between disease-specific and generic health status questionnaires in patients with advanced COPD: a one-year observational study." Health and quality of life outcomes 10 doi:10.1186/1477-7525-10-98

2011

Vanfleteren Lowie E G W, Franssen Frits M E, Uszko-Lencer Nicole H M K, Spruit Martijn A, Celis Mieke, et al. 2011. "Frequency and relevance of ischemic electrocardiographic findings in patients with chronic obstructive pulmonary disease." The American journal of cardiology 108 (11) doi:10.1016/j.amjcard.2011.07.027
Janssen Daisy J A, Franssen Frits M E, Wouters Emiel F M, Schols Jos M G A, Spruit Martijn A 2011. "Impaired health status and care dependency in patients with advanced COPD or chronic heart failure." Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20 (10) doi:10.1007/s11136-011-9892-9
Annegarn Janneke, Spruit Martijn A, Uszko-Lencer Nicole H M K, Vanbelle Sophie, Savelberg Hans H C M, et al. 2011. "Objective physical activity assessment in patients with chronic organ failure: a validation study of a new single-unit activity monitor." Archives of physical medicine and rehabilitation 92 (11) doi:10.1016/j.apmr.2011.06.021
Kuipers Ine, Guala Amy S, Aesif Scott W, Konings Gonda, Bouwman Freek G, et al. 2011. "Cigarette smoke targets glutaredoxin 1, increasing s-glutathionylation and epithelial cell death." American journal of respiratory cell and molecular biology 45 (5) doi:10.1165/rcmb.2010-0249OC
Vaes Anouk W, Wouters Emiel F M, Franssen Frits M E, Uszko-Lencer Nicole H M K, Stakenborg Koen H P, et al. 2011. "Task-related oxygen uptake during domestic activities of daily life in patients with COPD and healthy elderly subjects." Chest 140 (4) doi:10.1378/chest.10-3005
Aesif Scott W, Kuipers Ine, van der Velden Jos, Tully Jane E, Guala Amy S, et al. 2011. "Activation of the glutaredoxin-1 gene by nuclear factor κB enhances signaling." Free radical biology & medicine 51 (6) doi:10.1016/j.freeradbiomed.2011.06.025
Spruit Martijn A, Wouters Emiel F M, Eterman Rose-Mieke A, Meijer Kenneth, Wagers Scott S, et al. 2011. "Task-related oxygen uptake and symptoms during activities of daily life in CHF patients and healthy subjects." European journal of applied physiology 111 (8) doi:10.1007/s00421-010-1794-y
Vogelmeier Claus F, Wouters Emiel F M 2011. "Treating the systemic effects of chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 8 (4) doi:10.1513/pats.201102-020RM
Breyer Marie-Kathrin, Rutten Erica P A, Vernooy Juanita H J, Spruit Martijn A, Dentener Mieke A, et al. 2011. "Gender differences in the adipose secretome system in chronic obstructive pulmonary disease (COPD): a pivotal role of leptin." Respiratory medicine 105 (7) doi:10.1016/j.rmed.2011.02.001
Franssen Frits M E, Sauerwein Hans P, Ackermans Mariette T, Rutten Erica P A, Wouters Emiel F M, Schols Annemie M W J 2011. "Increased postabsorptive and exercise-induced whole-body glucose production in patients with chronic obstructive pulmonary disease." Metabolism: clinical and experimental 60 (7) doi:10.1016/j.metabol.2010.09.004
Janssen Daisy J A, Spruit Martijn A, Uszko-Lencer Nicole H, Schols Jos M G A, Wouters Emiel F M 2011. "Symptoms, comorbidities, and health care in advanced chronic obstructive pulmonary disease or chronic heart failure." Journal of palliative medicine 14 (6) doi:10.1089/jpm.2010.0479
Janssen Daisy J A, Spruit Martijn A, Schols Jos M G A, Wouters Emiel F M 2011. "A call for high-quality advance care planning in outpatients with severe COPD or chronic heart failure." Chest 139 (5) doi:10.1378/chest.10-1753
Graat-Verboom Lidwien, van den Borne Ben E E M, Smeenk Frank W J M, Spruit Martijn A, Wouters Emiel F M 2011. "Osteoporosis in COPD outpatients based on bone mineral density and vertebral fractures." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 26 (3) doi:10.1002/jbmr.257
Hanania Nicola A, Müllerova Hana, Locantore Nicholas W, Vestbo Jørgen, Watkins Michael L, et al. 2011. "Determinants of depression in the ECLIPSE chronic obstructive pulmonary disease cohort." American journal of respiratory and critical care medicine 183 (5) doi:10.1164/rccm.201003-0472OC
Sillen Maurice J H, Wouters Emiel F M, Franssen Frits M E, Meijer Kenneth, Stakenborg Koen H P, Spruit Martijn A 2011. "Oxygen uptake, ventilation, and symptoms during low-frequency versus high-frequency NMES in COPD: a pilot study." Lung 189 (1) doi:10.1007/s00408-010-9265-0
Franssen Frits M E, Spruit Martijn A, Wouters Emiel F M 2011. "Determinants of polypharmacy and compliance with GOLD guidelines in patients with chronic obstructive pulmonary disease." International journal of chronic obstructive pulmonary disease 6 doi:10.2147/COPD.S24443
Rutten Erica P A, Grydeland Thomas B, Pillai Sreekumar G, Wagers Scott, Dirksen Asger, et al. 2011. "Quantitative CT: Associations between Emphysema, Airway Wall Thickness and Body Composition in COPD." Pulmonary medicine 2011 doi:10.1155/2011/419328

2010

Rutten Erica P A, Breyer Marie K, Spruit Martijn A, Hofstra Trineke, van Melick Paula P M J, et al. 2010. "Abdominal fat mass contributes to the systemic inflammation in chronic obstructive pulmonary disease." Clinical nutrition (Edinburgh, Scotland) 29 (6) doi:10.1016/j.clnu.2010.04.007
Sørheim Inga-Cecilie, Bakke Per, Gulsvik Amund, Pillai Sreekumar G, Johannessen Ane, et al. 2010. "α₁-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts." Chest 138 (5) doi:10.1378/chest.10-0746
Hurst John R, Vestbo Jørgen, Anzueto Antonio, Locantore Nicholas, Müllerova Hana, et al. 2010. "Susceptibility to exacerbation in chronic obstructive pulmonary disease." The New England journal of medicine 363 (12) doi:10.1056/NEJMoa0909883
Han MeiLan K, Agusti Alvar, Calverley Peter M, Celli Bartolome R, Criner Gerard, et al. 2010. "Chronic obstructive pulmonary disease phenotypes: the future of COPD." American journal of respiratory and critical care medicine 182 (5) doi:10.1164/rccm.200912-1843CC
Hersh Craig P, Pillai Sreekumar G, Zhu Guohua, Lomas David A, Bakke Per, et al. 2010. "Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene." American journal of respiratory and critical care medicine 182 (5) doi:10.1164/rccm.200910-1586OC
Janssen Daisy J A, Spruit Martijn A, Leue Carsten, Gijsen Candy, Hameleers Henry, et al. 2010. "Symptoms of anxiety and depression in COPD patients entering pulmonary rehabilitation." Chronic respiratory disease 7 (3) doi:10.1177/1479972310369285
Vernooy Juanita H J, Bracke Ken R, Drummen Nadja E A, Pauwels Nele S A, Zabeau Lennart, et al. 2010. "Leptin modulates innate and adaptive immune cell recruitment after cigarette smoke exposure in mice." Journal of immunology (Baltimore, Md. : 1950) 184 (12) doi:10.4049/jimmunol.0900963
Spruit Martijn A, Watkins Michael L, Edwards Lisa D, Vestbo Jørgen, Calverley Peter M A, et al. 2010. "Determinants of poor 6-min walking distance in patients with COPD: the ECLIPSE cohort." Respiratory medicine 104 (6) doi:10.1016/j.rmed.2009.12.007
Bracke Ken R, Dentener Mieke A, Papakonstantinou Eleni, Vernooy Juanita H J, Demoor Tine, et al. 2010. "Enhanced deposition of low-molecular-weight hyaluronan in lungs of cigarette smoke-exposed mice." American journal of respiratory cell and molecular biology 42 (6) doi:10.1165/rcmb.2008-0424OC
Janssen Daisy J A, Spruit Martijn A, Alsemgeest Ton P G, Does Joan D, Schols Jos M G A, Wouters Emiel F M 2010. "A patient-centred interdisciplinary palliative care programme for end-stage chronic respiratory diseases." International journal of palliative nursing 16 (4) doi:
Geraets Liesbeth, Haegens Astrid, Weseler Antje R, Brauers Karen, Vernooy Juanita H J, et al. 2010. "Inhibition of acute pulmonary and systemic inflammation by 1,7-dimethylxanthine." European journal of pharmacology 629 (1-3) doi:10.1016/j.ejphar.2009.11.064
Graat-Verboom Lidwien, Spruit Martijn A, van den Borne Ben E E M, Smeenk Frank W J M, Wouters Emiel F M 2010. "Whole-Body versus Local DXA-Scan for the Diagnosis of Osteoporosis in COPD Patients." Journal of osteoporosis 2010 doi:10.4061/2010/640878
Breyer Marie-Kathrin, Breyer-Kohansal Robab, Funk Georg-Christian, Dornhofer Nicole, Spruit Martijn A, et al. 2010. "Nordic walking improves daily physical activities in COPD: a randomised controlled trial." Respiratory research 11 doi:10.1186/1465-9921-11-112
Güngör Nejla, Haegens Astrid, Knaapen Ad M, Godschalk Roger W L, Chiu Roland K, et al. 2010. "Lung inflammation is associated with reduced pulmonary nucleotide excision repair in vivo." Mutagenesis 25 (1) doi:10.1093/mutage/gep049
Rutten Erica P A, Spruit Martijn A, Wouters Emiel F M 2010. "Critical view on diagnosing muscle wasting by single-frequency bio-electrical impedance in COPD." Respiratory medicine 104 (1) doi:10.1016/j.rmed.2009.07.004

2009

Breyer Marie-Kathrin, Spruit Martijn A, Celis Annemie P M, Rutten Erica P A, Janssen Paul P, Wouters Emiel F M 2009. "Highly elevated C-reactive protein levels in obese patients with COPD: a fat chance?" Clinical nutrition (Edinburgh, Scotland) 28 (6) doi:10.1016/j.clnu.2009.05.005
Wouters Emiel F M, Vanderhoven Ingrid M L 2009. "Pulmonary rehabilitation and integrated care." Seminars in respiratory and critical care medicine 30 (6) doi:10.1055/s-0029-1242641
Van Schayck Constant P, Kaper Janneke, Wagena Edwin J, Wouters Emiel F M, Severens Johannes L 2009. "The cost-effectiveness of antidepressants for smoking cessation in chronic obstructive pulmonary disease (COPD) patients." Addiction (Abingdon, England) 104 (12) doi:10.1111/j.1360-0443.2009.02723.x
Wouters Emiel F M, Reynaert Niki L, Dentener Mieke A, Vernooy Juanita H J 2009. "Systemic and local inflammation in asthma and chronic obstructive pulmonary disease: is there a connection?" Proceedings of the American Thoracic Society 6 (8) doi:10.1513/pats.200907-073DP
Effing Tanja W, Kerstjens Huib A M, Monninkhof Evelyn M, van der Valk Paul D L P M, Wouters Emiel F M, et al. 2009. "Definitions of exacerbations: does it really matter in clinical trials on COPD?" Chest 136 (3) doi:10.1378/chest.08-1680
Graat-Verboom Lidwien, Spruit Martijn A, van den Borne Ben E E M, Smeenk Frank W J M, Martens Elisabeth J, et al. 2009. "Correlates of osteoporosis in chronic obstructive pulmonary disease: An underestimated systemic component." Respiratory medicine 103 (8) doi:10.1016/j.rmed.2009.02.014
Spruit Martijn A, Janssen Daisy J A, Franssen Frits M E, Wouters Emiel F M 2009. "Rehabilitation and palliative care in lung fibrosis." Respirology (Carlton, Vic.) 14 (6) doi:10.1111/j.1440-1843.2009.01599.x
Yanbaeva Dilyara G, Wouters Emiel F M, Dentener Mieke A, Spruit Martijn A, Reynaert Niki L 2009. "Association of glutathione-S-transferase omega haplotypes with susceptibility to chronic obstructive pulmonary disease." Free radical research 43 (8) doi:10.1080/10715760903038440
Sillen Maurice J H, Speksnijder Caroline M, Eterman Rose-Miek A, Janssen Paul P, Wagers Scott S, et al. 2009. "Effects of neuromuscular electrical stimulation of muscles of ambulation in patients with chronic heart failure or COPD: a systematic review of the English-language literature." Chest 136 (1) doi:10.1378/chest.08-2481
Willems Daniëlle C M, Joore Manuela A, Nieman Fred H M, Severens Johan L, Wouters Emiel F M, Hendriks Johannes J E 2009. "Using EQ-5D in children with asthma, rheumatic disorders, diabetes, and speech/language and/or hearing disorders." International journal of technology assessment in health care 25 (3) doi:10.1017/S0266462309990171
Haegens Astrid, Heeringa Peter, van Suylen Robert Jan, Steele Chad, Aratani Yasuaki, et al. 2009. "Myeloperoxidase deficiency attenuates lipopolysaccharide-induced acute lung inflammation and subsequent cytokine and chemokine production." Journal of immunology (Baltimore, Md. : 1950) 182 (12) doi:10.4049/jimmunol.0800377
Gosker Harry R, Langen Ramon C J, Bracke Ken R, Joos Guy F, Brusselle Guy G, et al. 2009. "Extrapulmonary manifestations of chronic obstructive pulmonary disease in a mouse model of chronic cigarette smoke exposure." American journal of respiratory cell and molecular biology 40 (6) doi:10.1165/rcmb.2008-0312OC
Geraets Liesbeth, Haegens Astrid, Brauers Karen, Haydock Jane A, Vernooy Juanita H J, et al. 2009. "Inhibition of LPS-induced pulmonary inflammation by specific flavonoids." Biochemical and biophysical research communications 382 (3) doi:10.1016/j.bbrc.2009.03.071
Weseler Antje R, Geraets Liesbeth, Moonen Harald J J, Manders Ralph J F, van Loon Luc J C, et al. 2009. "Poly (ADP-ribose) polymerase-1-inhibiting flavonoids attenuate cytokine release in blood from male patients with chronic obstructive pulmonary disease or type 2 diabetes." The Journal of nutrition 139 (5) doi:10.3945/jn.108.102756
Pitta Fábio, Breyer Marie-Kathrin, Hernandes Nídia A, Teixeira Denílson, Sant'Anna Thaís J P, et al. 2009. "Comparison of daily physical activity between COPD patients from Central Europe and South America." Respiratory medicine 103 (3) doi:10.1016/j.rmed.2008.09.019
Yanbaeva Dilyara G, Dentener Mieke A, Spruit Martijn A, Houwing-Duistermaat Jeanine J, Kotz Daniel, et al. 2009. "IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study." BMC medical genetics 10 doi:10.1186/1471-2350-10-23
Chavannes Niels H, Schermer Tjard R J, Wouters Emiel F M, Akkermans Reinier P, Dekhuijzen Richard P N, et al. 2009. "Predictive value and utility of oral steroid testing for treatment of COPD in primary care: the COOPT study." International journal of chronic obstructive pulmonary disease 4 doi:

2008

Patel Bipen D, Coxson Harvey O, Pillai Sreekumar G, Agustí Alvar G N, Calverley Peter M A, et al. 2008. "Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 178 (5) doi:10.1164/rccm.200801-059OC
Willems Daniëlle C M, Joore Manuela A, Hendriks Johannes J E, Nieman Fred H M, Severens Johan L, Wouters Emiel F M 2008. "The effectiveness of nurse-led telemonitoring of asthma: results of a randomized controlled trial." Journal of evaluation in clinical practice 14 (4) doi:10.1111/j.1365-2753.2007.00936.x
Rutten Erica P A, Engelen Marielle P K J, Gosker Harry, Bast Aalt, Cosemans Kirsten, et al. 2008. "Metabolic and functional effects of glutamate intake in patients with chronic obstructive pulmonary disease (COPD)." Clinical nutrition (Edinburgh, Scotland) 27 (3) doi:10.1016/j.clnu.2008.03.001
Sillen Maurice J H, Janssen Paul P, Akkermans Marco A, Wouters Emiel F M, Spruit Martijn A 2008. "The metabolic response during resistance training and neuromuscular electrical stimulation (NMES) in patients with COPD, a pilot study." Respiratory medicine 102 (5) doi:10.1016/j.rmed.2008.01.013
Groenewegen Karin H, Postma Dirkje S, Hop Wim C J, Wielders Pascal L M L, Schlösser Noel J J, Wouters Emiel F M 2008. "Increased systemic inflammation is a risk factor for COPD exacerbations." Chest 133 (2) doi:10.1378/chest.07-1342
Dentener Mieke A, Creutzberg Eva C, Pennings Herman-Jan, Rijkers Ger T, Mercken Evi, Wouters Emiel F M 2008. "Effect of infliximab on local and systemic inflammation in chronic obstructive pulmonary disease: a pilot study." Respiration; international review of thoracic diseases 76 (3) doi:10.1159/000117386
Pauwels Romain, Joos Guy F, Fogarty Charles, Faiferman Isidore, Hirschberg Sandra, et al. 2008. "Bronchodilating effect of combined therapy with ipratropium bromide and ondansetron in patients with COPD." Pulmonary pharmacology & therapeutics 21 (2) doi:10.1016/j.pupt.2007.10.002
Janssen Daisy J A, Wouters Emiel F M, Schols Jos M G A, Spruit Martijn A 2008. "Self-perceived symptoms and care needs of patients with severe to very severe chronic obstructive pulmonary disease, congestive heart failure or chronic renal failure and its consequences for their closest relatives: the research protocol." BMC palliative care 7 doi:10.1186/1472-684X-7-5

2007

Spruit Martijn A, Pennings Herman-Jan, Janssen Paul P, Does Joan D, Scroyen Sigrid, et al. 2007. "Extra-pulmonary features in COPD patients entering rehabilitation after stratification for MRC dyspnea grade." Respiratory medicine 101 (12) doi:10.1016/j.rmed.2007.07.003
Wouters Emiel F M, Groenewegen Karin H, Dentener Mieke A, Vernooy Juanita H J 2007. "Systemic inflammation in chronic obstructive pulmonary disease: the role of exacerbations." Proceedings of the American Thoracic Society 4 (8) doi:10.1513/pats.200706-071TH
Geraets Liesbeth, Moonen Harald J J, Brauers Karen, Gottschalk Ralph W H, Wouters Emiel F M, et al. 2007. "Flavone as PARP-1 inhibitor: its effect on lipopolysaccharide induced gene-expression." European journal of pharmacology 573 (1-3) doi:10.1016/j.ejphar.2007.07.013
Groenewegen Karin H, Dentener Mieke A, Wouters Emiel F M 2007. "Longitudinal follow-up of systemic inflammation after acute exacerbations of COPD." Respiratory medicine 101 (11) doi:10.1016/j.rmed.2007.05.026
Gosker Harry R, Zeegers Maurice P, Wouters Emiel F M, Schols Annemie M W J 2007. "Muscle fibre type shifting in the vastus lateralis of patients with COPD is associated with disease severity: a systematic review and meta-analysis." Thorax 62 (11) doi:10.1136/thx.2007.078980
Geraets Liesbeth, Moonen Harald J J, Brauers Karen, Wouters Emiel F M, Bast Aalt, Hageman Geja J 2007. "Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells." The Journal of nutrition 137 (10) doi:
Scharloo Margreet, Kaptein Adrian A, Schlösser Maryanne, Pouwels Harry, Bel Elisabeth H, et al. 2007. "Illness perceptions and quality of life in patients with chronic obstructive pulmonary disease." The Journal of asthma : official journal of the Association for the Care of Asthma 44 (7) doi:10.1080/02770900701537438
van der Velden Jos L J, Langen Ramon C J, Kelders Marco C J M, Willems Jodil, Wouters Emiel F M, et al. 2007. "Myogenic differentiation during regrowth of atrophied skeletal muscle is associated with inactivation of GSK-3beta." American journal of physiology. Cell physiology 292 (5) doi:10.1152/ajpcell.00504.2006
Yanbaeva Dilyara G, Dentener Mieke A, Creutzberg Eva C, Wesseling Geertjan, Wouters Emiel F M 2007. "Systemic effects of smoking." Chest 131 (5) doi:10.1378/chest.06-2179
Reynaert Niki L, Aesif Scott W, McGovern Toby, Brown Amy, Wouters Emiel F M, et al. 2007. "Catalase overexpression fails to attenuate allergic airways disease in the mouse." Journal of immunology (Baltimore, Md. : 1950) 178 (6) doi:
Vernooy Juanita H J, Möller Gertrude M, van Suylen Robert J, van Spijk Marlies P, Cloots Roy H E, et al. 2007. "Increased granzyme A expression in type II pneumocytes of patients with severe chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 175 (5) doi:10.1164/rccm.200602-169OC
Engelen Mariëlle P K J, Rutten Erica P A, De Castro Carmen L N, Wouters Emiel F M, Schols Annemie M W J, Deutz Nicolaas E P 2007. "Supplementation of soy protein with branched-chain amino acids alters protein metabolism in healthy elderly and even more in patients with chronic obstructive pulmonary disease." The American journal of clinical nutrition 85 (2) doi:
Reynaert Niki L, Wouters Emiel F M, Janssen-Heininger Yvonne M W 2007. "Modulation of glutaredoxin-1 expression in a mouse model of allergic airway disease." American journal of respiratory cell and molecular biology 36 (2) doi:10.1165/rcmb.2006-0259RC
Bolton Charlotte E, Broekhuizen Roelinka, Ionescu Alina A, Nixon Lisette S, Wouters Emiel F M, et al. 2007. "Cellular protein breakdown and systemic inflammation are unaffected by pulmonary rehabilitation in COPD." Thorax 62 (2) doi:10.1136/thx.2006.060368
Spruit Martijn A, Wouters Emiel F M 2007. "New modalities of pulmonary rehabilitation in patients with chronic obstructive pulmonary disease." Sports medicine (Auckland, N.Z.) 37 (6) doi:
Willems Daniëlle C M, Joore Manuela A, Hendriks Johannes J E, Wouters Emiel F M, Severens Johan L 2007. "Cost-effectiveness of a nurse-led telemonitoring intervention based on peak expiratory flow measurements in asthmatics: results of a randomised controlled trial." Cost effectiveness and resource allocation : C/E 5 doi:10.1186/1478-7547-5-10
Willems Daniëlle C M, Joore Manuela A, Hendriks Johannes J E, van Duurling Raymond A H, Wouters Emiel F M, Severens Johan L Y 2007. "Process evaluation of a nurse-led telemonitoring programme for patients with asthma." Journal of telemedicine and telecare 13 (6) doi:10.1258/135763307781644898

2006

Langen Ramon C J, Schols Annemie M W J, Kelders Marco C J M, van der Velden Jos L J, Wouters Emiel F M, Janssen-Heininger Yvonne M W 2006. "Muscle wasting and impaired muscle regeneration in a murine model of chronic pulmonary inflammation." American journal of respiratory cell and molecular biology 35 (6) doi:10.1165/rcmb.2006-0103OC
Geraets Liesbeth, Moonen Harald J J, Wouters Emiel F M, Bast Aalt, Hageman Geja J 2006. "Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations." Biochemical pharmacology 72 (7) doi:10.1016/j.bcp.2006.06.023
Reynaert Niki L, van der Vliet Albert, Guala Amy S, McGovern Toby, Hristova Milena, et al. 2006. "Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta." Proceedings of the National Academy of Sciences of the United States of America 103 (35) doi:10.1073/pnas.0603290103
Wouters Emiel F M 2006. "Approaches to improving health status in chronic obstructive pulmonary disease: one or several?" Proceedings of the American Thoracic Society 3 (3) doi:10.1513/pats.200511-118SF
Spruit Martijn A, Janssen Paul P, Willemsen Sonja C P, Hochstenbag Monique M H, Wouters Emiel F M 2006. "Exercise capacity before and after an 8-week multidisciplinary inpatient rehabilitation program in lung cancer patients: a pilot study." Lung cancer (Amsterdam, Netherlands) 52 (2) doi:10.1016/j.lungcan.2006.01.003
Rutten Erica P A, Engelen Marielle P K J, Wouters Emiel F M, Deutz Nicolaas E P, Schols Annemie M W J 2006. "Effect of glutamate ingestion on whole-body glutamate turnover in healthy elderly and patients with chronic obstructive pulmonary disease." Nutrition (Burbank, Los Angeles County, Calif.) 22 (5) doi:10.1016/j.nut.2005.12.005
Gosker Harry R, Schrauwen Patrick, Broekhuizen Roelinka, Hesselink Matthijs K C, Moonen-Kornips Esther, et al. 2006. "Exercise training restores uncoupling protein-3 content in limb muscles of patients with chronic obstructive pulmonary disease." American journal of physiology. Endocrinology and metabolism 290 (5) doi:10.1152/ajpendo.00336.2005
Rutten Erica P A, Franssen Frits M E, Engelen Marielle P K J, Wouters Emiel F M, Deutz Nicolaas E P, Schols Annemie M W J 2006. "Greater whole-body myofibrillar protein breakdown in cachectic patients with chronic obstructive pulmonary disease." The American journal of clinical nutrition 83 (4) doi:
Yanbaeva Dilyara G, Dentener Mieke A, Creutzberg Eva C, Wouters Emiel F M 2006. "Systemic inflammation in COPD: is genetic susceptibility a key factor?" COPD 3 (1) doi:
Reynaert Niki L, Ckless Karina, Guala Amy S, Wouters Emiel F M, van der Vliet Albert, Janssen-Heininger Yvonne M W 2006. "In situ detection of S-glutathionylated proteins following glutaredoxin-1 catalyzed cysteine derivatization." Biochimica et biophysica acta 1760 (3) doi:10.1016/j.bbagen.2006.01.006
van der Velden Jos L J, Langen Ramon C J, Kelders Marco C J M, Wouters Emiel F M, Janssen-Heininger Yvonne M W, Schols Annemie M W J 2006. "Inhibition of glycogen synthase kinase-3beta activity is sufficient to stimulate myogenic differentiation." American journal of physiology. Cell physiology 290 (2) doi:10.1152/ajpcell.00068.2005
Chavannes Niels H, Vernooy Juanita H J, Schermer Tjard R J, Jacobs Jan A, Dentener Mieke A, et al. 2006. "Patterns of inflammation and the use of reversibility testing in smokers with airway complaints." BMC pulmonary medicine 6 doi:10.1186/1471-2466-6-11
Willems Daniëlle C M, Joore Manuela A, Hendriks Johannes J E, Wouters Emiel F M, Severens Johan L 2006. "Cost-effectiveness of self-management in asthma: a systematic review of peak flow monitoring interventions." International journal of technology assessment in health care 22 (4) doi:10.1017/S026646230605135X
Rutten Erica P A, Engelen Marielle P K J, Wouters Emiel F M, Schols Annemie M W J, Deutz Nicolaas E P 2006. "Metabolic effects of glutamine and glutamate ingestion in healthy subjects and in persons with chronic obstructive pulmonary disease." The American journal of clinical nutrition 83 (1) doi:

2005

Moonen Harald J J, Geraets Liesbeth, Vaarhorst Anika, Bast Aalt, Wouters Emiel F M, Hageman Geja J 2005. "Theophylline prevents NAD+ depletion via PARP-1 inhibition in human pulmonary epithelial cells." Biochemical and biophysical research communications 338 (4) doi:10.1016/j.bbrc.2005.10.159
Celli Bartolome R, Calverley Peter M A, Rennard Stephen I, Wouters Emiel F M, Agusti Alvar, et al. 2005. "Proposal for a multidimensional staging system for chronic obstructive pulmonary disease." Respiratory medicine 99 (12) doi:10.1016/j.rmed.2005.03.019
Mercken Evi M, Hageman Geja J, Schols Annemie M W J, Akkermans Marco A, Bast Aalt, Wouters Emiel F M 2005. "Rehabilitation decreases exercise-induced oxidative stress in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 172 (8) doi:10.1164/rccm.200411-1580OC
Rutten Erica P A, Engelen Marielle P K J, Castro Carmen L N, Wouters Emiel F M, Schols Annemie M W J, Deutz Nicolaas E P 2005. "Decreased whole-body and splanchnic glutamate metabolism in healthy elderly men and patients with chronic obstructive pulmonary disease in the postabsorptive state and in response to feeding." The Journal of nutrition 135 (9) doi:
Engelen Mariëlle P K J, Rutten Erica P A, De Castro Carmen L N, Wouters Emiel F M, Schols Annemie M W J, Deutz Nicolaas E P 2005. "Altered interorgan response to feeding in patients with chronic obstructive pulmonary disease." The American journal of clinical nutrition 82 (2) doi:
Broekhuizen Roelinka, Creutzberg Eva C, Weling-Scheepers Clarie A P M, Wouters Emiel F M, Schols Annemie M W J 2005. "Optimizing oral nutritional drink supplementation in patients with chronic obstructive pulmonary disease." The British journal of nutrition 93 (6) doi:
Gosker Harry R, Bast Aalt, Haenen Guido R M M, Fischer Marc A J G, van der Vusse Ger J, et al. 2005. "Altered antioxidant status in peripheral skeletal muscle of patients with COPD." Respiratory medicine 99 (1) doi:
Reynaert Niki L, Ckless Karina, Wouters Emiel F M, van der Vliet Albert, Janssen-Heininger Yvonne M W 2005. "Nitric oxide and redox signaling in allergic airway inflammation." Antioxidants & redox signaling 7 (1-2) doi:10.1089/ars.2005.7.129
Franssen Frits M E, Broekhuizen Roelinka, Janssen Paul P, Wouters Emiel F M, Schols Annemie M W J 2005. "Limb muscle dysfunction in COPD: effects of muscle wasting and exercise training." Medicine and science in sports and exercise 37 (1) doi:
Wouters Emiel F M 2005. "Local and systemic inflammation in chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 2 (1) doi:10.1513/pats.200408-039MS
Wagena Edwin J, van Amelsvoort Ludovic G P M, Kant Ijmert, Wouters Emiel F M 2005. "Chronic bronchitis, cigarette smoking, and the subsequent onset of depression and anxiety: results from a prospective population-based cohort study." Psychosomatic medicine 67 (4) doi:10.1097/01.psy.0000171197.29484.6b

2004

Vernooy Juanita H J, Lindeman Jan H N, Jacobs Jan A, Hanemaaijer Roeland, Wouters Emiel F M 2004. "Increased activity of matrix metalloproteinase-8 and matrix metalloproteinase-9 in induced sputum from patients with COPD." Chest 126 (6) doi:10.1378/chest.126.6.1802
de Blaauw Ivo, Schols Annemie M W J, Koerts-deLang Esther, Wouters Emiel F M, Deutz Nicolaas E P 2004. "De novo glutamine synthesis induced by corticosteroids in vivo in rats is secondary to weight loss." Clinical nutrition (Edinburgh, Scotland) 23 (5) doi:10.1016/j.clnu.2004.01.004
Reynaert Niki L, Ckless Karina, Korn Solange H, Vos Nanda, Guala Amy S, et al. 2004. "Nitric oxide represses inhibitory kappaB kinase through S-nitrosylation." Proceedings of the National Academy of Sciences of the United States of America 101 (24) doi:10.1073/pnas.0400588101
Verbraecken Johan, Hoitsma Elske, van der Grinten Chris P M, Cobben Nicolle A M, Wouters Emiel F M, Drent Marjolein 2004. "Sleep disturbances associated with periodic leg movements in chronic sarcoidosis." Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders 21 (2) doi:
Franssen Frits M E, Broekhuizen Roelinka, Janssen Paul P, Wouters Emiel F M, Schols Annemie M W J 2004. "Effects of whole-body exercise training on body composition and functional capacity in normal-weight patients with COPD." Chest 125 (6) doi:
Langen Ramon C J, Van Der Velden Jos L J, Schols Annemie M W J, Kelders Marco C J M, Wouters Emiel F M, Janssen-Heininger Yvonne M W 2004. "Tumor necrosis factor-alpha inhibits myogenic differentiation through MyoD protein destabilization." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 18 (2) doi:10.1096/fj.03-0251com
Wagena Edwin J, Kant Ijmert, van Amelsvoort Ludovic G P M, Wouters Emiel F M, van Schayck Constant P, Swaen Gerard M H 2004. "Risk of depression and anxiety in employees with chronic bronchitis: the modifying effect of cigarette smoking." Psychosomatic medicine 66 (5) doi:10.1097/01.psy.0000138127.00991.cf
Wagena Edwin J, Kant Ijmert, Huibers Marcus J H, van Amelsvoort Ludovic G P M, Swaen Gerard M H, et al. 2004. "Psychological distress and depressed mood in employees with asthma, chronic bronchitis or emphysema: a population-based observational study on prevalence and the relationship with smoking cigarettes." European journal of epidemiology 19 (2) doi:

2003

Drent Marjolein, De Vries Jolanda, Lenters Merinke, Lamers Rob J S, Rothkranz-Kos Snjezana, et al. 2003. "Sarcoidosis: assessment of disease severity using HRCT." European radiology 13 (11) doi:10.1007/s00330-003-1965-x
Creutzberg Eva C, Wouters Emiel F M, Mostert Rob, Pluymers Rob J, Schols Annemie M W J 2003. "A role for anabolic steroids in the rehabilitation of patients with COPD? A double-blind, placebo-controlled, randomized trial." Chest 124 (5) doi:
Groenewegen Karin H, Schols Annemie M W J, Wouters Emiel F M 2003. "Mortality and mortality-related factors after hospitalization for acute exacerbation of COPD." Chest 124 (2) doi:
Hageman Geja J, Larik Ingrid, Pennings Herman Jan, Haenen Guido R M M, Wouters Emiel F M, Bast Aalt 2003. "Systemic poly(ADP-ribose) polymerase-1 activation, chronic inflammation, and oxidative stress in COPD patients." Free radical biology & medicine 35 (2) doi:
Groenewegen Karin H, Wouters Emiel F M 2003. "Bacterial infections in patients requiring admission for an acute exacerbation of COPD; a 1-year prospective study." Respiratory medicine 97 (7) doi:
Goris Annelies H C, Vermeeren Marja A P, Wouters Emiel F M, Schols Annemie M W J, Westerterp Klaas R 2003. "Energy balance in depleted ambulatory patients with chronic obstructive pulmonary disease: the effect of physical activity and oral nutritional supplementation." The British journal of nutrition 89 (5) doi:10.1079/BJN2003838
Gosker Harry R, Lencer Nicole H M K, Franssen Frits M E, van der Vusse Ger J, Wouters Emiel F M, Schols Annemie M W J 2003. "Striking similarities in systemic factors contributing to decreased exercise capacity in patients with severe chronic heart failure or COPD." Chest 123 (5) doi:
Engelen Mariëlle P K J, Deutz Nicolaas E P, Mostert Rob, Wouters Emiel F M, Schols Annemie M W J 2003. "Response of whole-body protein and urea turnover to exercise differs between patients with chronic obstructive pulmonary disease with and without emphysema." The American journal of clinical nutrition 77 (4) doi:
Creutzberg Eva C, Wouters Emiel F M, Mostert Rob, Weling-Scheepers Clarie A P M, Schols Annemie M W J 2003. "Efficacy of nutritional supplementation therapy in depleted patients with chronic obstructive pulmonary disease." Nutrition (Burbank, Los Angeles County, Calif.) 19 (2) doi:
Wagena Edwin J, Zeegers Maurice P A, van Schayck Constant P, Wouters Emiel F M 2003. "Benefits and risks of pharmacological smoking cessation therapies in chronic obstructive pulmonary disease." Drug safety : an international journal of medical toxicology and drug experience 26 (6) doi:
Langen Ramon C J, Schols Annemie M W J, Kelders Marco C J M, Wouters Emiel F M, Janssen-Heininger Yvonne M W 2003. "Enhanced myogenic differentiation by extracellular matrix is regulated at the early stages of myogenesis." In vitro cellular & developmental biology. Animal 39 (3-4) doi:10.1007/s11626-003-0011-2

2002

Franssen Frits M E, Wouters Emiel F M, Baarends Erica M, Akkermans Marco A, Schols Annemie M W J 2002. "Arm mechanical efficiency and arm exercise capacity are relatively preserved in chronic obstructive pulmonary disease." Medicine and science in sports and exercise 34 (10) doi:10.1249/01.MSS.0000035989.68599.4f
Langen Ramon C J, Schols Annemie M W J, Kelders Marco C J M, Van Der Velden Jos L J, Wouters Emiel F M, Janssen-Heininger Yvonne M W 2002. "Tumor necrosis factor-alpha inhibits myogenesis through redox-dependent and -independent pathways." American journal of physiology. Cell physiology 283 (3) doi:10.1152/ajpcell.00418.2001
Godschalk Roger W L, Feldker Dorien E M, Borm Paul J A, Wouters Emiel F M, van Schooten Frederik-Jan 2002. "Body mass index modulates aromatic DNA adduct levels and their persistence in smokers." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 11 (8) doi:
Langendijk Johannes A, Aaronson Neil K, de Jong Jos M A, ten Velde Guul P M, Muller Martin J, et al. 2002. "Quality of life after curative radiotherapy in Stage I non-small-cell lung cancer." International journal of radiation oncology, biology, physics 53 (4) doi:
Gosker Harry R, Engelen Mariëlle P K J, van Mameren Henk, van Dijk Paul J, van der Vusse Ger J, et al. 2002. "Muscle fiber type IIX atrophy is involved in the loss of fat-free mass in chronic obstructive pulmonary disease." The American journal of clinical nutrition 76 (1) doi:
Rothkrantz-Kos Snjezana, Drent Marjolein, Vuil Herma, De Boer Martin, Bast Aalt, et al. 2002. "Decreased redox state in red blood cells from patients with sarcoidosis." Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders 19 (2) doi:
Vernooy Juanita H J, Dentener Mieke A, van Suylen Robert J, Buurman Wim A, Wouters Emiel F M 2002. "Long-term intratracheal lipopolysaccharide exposure in mice results in chronic lung inflammation and persistent pathology." American journal of respiratory cell and molecular biology 26 (1) doi:10.1165/ajrcmb.26.1.4652
Küçükaycan Mehmet, Van Krugten Michiel, Pennings Herman-Jan, Huizinga Tom W J, Buurman Wim A, et al. 2002. "Tumor necrosis factor-alpha +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease." Respiratory research 3 doi: