Silverman Edwin K

Top coauthors of Silverman Edwin K

Crapo James D (70 papers)

Hersh Craig P (68 papers)

Cho Michael H (67 papers)

Weiss Scott T (59 papers)

Washko George R (55 papers)

List of Silverman Edwin K publications

2016

Halper-Stromberg Eitan, Cho Michael H, Wilson Carla, Nevrekar Dipti, Crapo James D, et al. 2016. "Visual Assessment of Chest CT Images is Independently Useful for Genetic Association Analysis in Studies of Chronic Obstructive Pulmonary Disease." Annals of the American Thoracic Society doi:10.1513/AnnalsATS.201606-427OC
Boueiz Adel, Lutz Sharon M, Cho Michael H, Hersh Craig P, Bowler Russell P, et al. 2016. "Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution." American journal of respiratory and critical care medicine doi:10.1164/rccm.201605-0997OC
Sul Jae Hoon, Cade Brian E, Cho Michael H, Qiao Dandi, Silverman Edwin K, et al. 2016. "Increasing Generality and Power of Rare-Variant Tests by Utilizing Extended Pedigrees." American journal of human genetics doi:10.1016/j.ajhg.2016.08.015
Morrow Jarrett D, Cho Michael H, Hersh Craig P, Pinto-Plata Victor, Celli Bartolome, et al. 2016. "DNA methylation profiling in human lung tissue identifies genes associated with COPD." Epigenetics doi:10.1080/15592294.2016.1226451
Hayden Lystra P, Cho Michael H, McDonald Merry-Lynn N, Crapo James D, Beaty Terri H, et al. 2016. "Susceptibility to Childhood Pneumonia: A Genome-Wide Analysis." American journal of respiratory cell and molecular biology doi:10.1165/rcmb.2016-0101OC
Sun Wei, Kechris Katerina, Jacobson Sean, Drummond M Bradley, Hawkins Gregory A, et al. 2016. "Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD." PLoS genetics 12 (8) doi:10.1371/journal.pgen.1006011
Silverman Edwin K 2016. "Risk of Lung Disease in PI MZ Heterozygotes. Current Status and Future Research Directions." Annals of the American Thoracic Society 13 (Supplement_4) doi:10.1513/AnnalsATS.201507-437KV
Lao Taotao, Jiang Zhiqiang, Yun Jeong, Qiu Weiliang, Guo Feng, et al. 2016. "Hhip haploinsufficiency sensitizes mice to age-related emphysema." Proceedings of the National Academy of Sciences of the United States of America doi:10.1073/pnas.1602342113
McGeachie Michael J, Yates Katherine P, Zhou Xiaobo, Guo Feng, Sternberg Alice L, et al. 2016. "Genetics and Genomics of Longitudinal Lung Function Patterns in Asthmatics." American journal of respiratory and critical care medicine doi:10.1164/rccm.201602-0250OC
Choi Sungkyoung, Lee Sungyoung, Qiao Dandi, Hardin Megan, Cho Michael H, et al. 2016. "FARVATX: Family-Based Rare Variant Association Test for X-Linked Genes." Genetic epidemiology doi:10.1002/gepi.21979
Wang Longfei, Lee Sungyoung, Gim Jungsoo, Qiao Dandi, Cho Michael, et al. 2016. "Family-Based Rare Variant Association Analysis: A Fast and Efficient Method of Multivariate Phenotype Association Analysis." Genetic epidemiology doi:10.1002/gepi.21985
McGeachie Michael J, Yates Katherine P, Zhou Xiaobo, Guo Feng, Sternberg Alice L, et al. 2016. "Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma." The New England journal of medicine 374 (19) doi:10.1056/NEJMoa1513737
Kim Victor, Zhao Huaqing, Boriek Aladin M, Anzueto Antonio, Soler Xavier, et al. 2016. "Persistent and Newly Developed Chronic Bronchitis Are Associated with Worse Outcomes in Chronic Obstructive Pulmonary Disease." Annals of the American Thoracic Society doi:10.1513/AnnalsATS.201512-800OC
Joppa Pavol, Tkacova Ruzena, Franssen Frits M E, Hanson Corrine, Rennard Stephen I, et al. 2016. "Sarcopenic Obesity, Functional Outcomes, and Systemic Inflammation in Patients With Chronic Obstructive Pulmonary Disease." Journal of the American Medical Directors Association doi:10.1016/j.jamda.2016.03.020
Chang Yale, Glass Kimberly, Liu Yang-Yu, Silverman Edwin K, Crapo James D, et al. 2016. "COPD subtypes identified by network-based clustering of blood gene expression." Genomics 107 (2-3) doi:10.1016/j.ygeno.2016.01.004
Putman Rachel K, Hatabu Hiroto, Araki Tetsuro, Gudmundsson Gunnar, Gao Wei, et al. 2016. "Association Between Interstitial Lung Abnormalities and All-Cause Mortality." JAMA 315 (7) doi:10.1001/jama.2016.0518
Jiang Zhiqiang, Lao Taotao, Qiu Weiliang, Polverino Francesca, Gupta Kushagra, et al. 2016. "A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-catenin." American journal of respiratory and critical care medicine doi:10.1164/rccm.201505-0999OC
Cloonan Suzanne M, Glass Kimberly, Laucho-Contreras Maria E, Bhashyam Abhiram R, Cervo Morgan, et al. 2016. "Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice." Nature medicine 22 (2) doi:10.1038/nm.4021
Bhatt Surya P, Soler Xavier, Wang Xin, Murray Susan, Anzueto Antonio R, et al. 2016. "Association Between Functional Small Airways Disease and FEV1 Decline in COPD." American journal of respiratory and critical care medicine doi:10.1164/rccm.201511-2219OC
Hobbs Brian D, Parker Margaret M, Chen Han, Lao Taotao, Hardin Megan, et al. 2016. "Exome Array Analysis Identifies A Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease." American journal of respiratory and critical care medicine doi:10.1164/rccm.201510-2053OC
Qiao Dandi, Lange Christoph, Beaty Terri H, Crapo James D, Barnes Kathleen C, et al. 2016. "Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease." American journal of respiratory and critical care medicine doi:10.1164/rccm.201506-1223OC
Bhatt Surya P, Wells James M, Kinney Gregory L, Washko George R, Budoff Matthew, et al. 2016. "β-Blockers are associated with a reduction in COPD exacerbations." Thorax 71 (1) doi:10.1136/thoraxjnl-2015-207251
Begum Ferdouse, Ruczinski Ingo, Li Shengchao, Silverman Edwin K, Cho Michael H, et al. 2016. "Identifying a Deletion Affecting Total Lung Capacity Among Subjects in the COPDGene Study Cohort." Genetic epidemiology 40 (1) doi:10.1002/gepi.21943
Hardin Megan, Foreman Marilyn, Dransfield Mark T, Hansel Nadia, Han MeiLan K, et al. 2016. "Sex-specific features of emphysema among current and former smokers with COPD." The European respiratory journal 47 (1) doi:10.1183/13993003.00996-2015
Begum Ferdouse, Ruczinski Ingo, Hokanson John E, Lutz Sharon M, Parker Margaret M, et al. 2016. "Hemizygous Deletion on Chromosome 3p26.1 Is Associated with Heavy Smoking among African American Subjects in the COPDGene Study." PloS one 11 (10) doi:10.1371/journal.pone.0164134
Kinney Gregory L, Baker Emma H, Klein Oana L, Black-Shinn Jennifer L, Wan Emily S, et al. 2016. "Pulmonary Predictors of Incident Diabetes in Smokers." Chronic obstructive pulmonary diseases (Miami, Fla.) 3 (4) doi:10.15326/jcopdf.3.4.2016.0137

2015

Prokopenko Dmitry, Hecker Julian, Silverman Edwin K, Pagano Marcello, Nöthen Markus M, et al. 2015. "Utilizing the Jaccard index to reveal population stratification in sequencing data: a simulation study and an application to the 1000 Genomes Project." Bioinformatics (Oxford, England) doi:10.1093/bioinformatics/btv752
Mathai Susan K, Pedersen Brent S, Smith Keith, Russell Pamela, Schwarz Marvin I, et al. 2015. "Desmoplakin (DSP) Variants are Associated with Idiopathic Pulmonary Fibrosis." American journal of respiratory and critical care medicine doi:10.1164/rccm.201509-1863OC
Lynch David A, Austin John H M, Hogg James C, Grenier Philippe A, Kauczor Hans-Ulrich, et al. 2015. "CT-Definable Subtypes of Chronic Obstructive Pulmonary Disease: A Statement of the Fleischner Society." Radiology 277 (1) doi:10.1148/radiol.2015141579
Yonchuk John G, Silverman Edwin K, Bowler Russell P, Agustí Alvar, Lomas David A, et al. 2015. "Circulating soluble receptor for advanced glycation end products (sRAGE) as a biomarker of emphysema and the RAGE axis in the lung." American journal of respiratory and critical care medicine 192 (7) doi:10.1164/rccm.201501-0137PP
Regan Elizabeth A, Lynch David A, Curran-Everett Douglas, Curtis Jeffrey L, Austin John H M, et al. 2015. "Clinical and Radiologic Disease in Smokers With Normal Spirometry." JAMA internal medicine 175 (9) doi:10.1001/jamainternmed.2015.2735
Cho Michael H, Castaldi Peter J, Hersh Craig P, Hobbs Brian D, Barr R Graham, et al. 2015. "A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes." American journal of respiratory and critical care medicine 192 (5) doi:10.1164/rccm.201501-0148OC
Gjerdevik Miriam, Grydeland Thomas B, Washko George R, Coxson Harvey O, Silverman Edwin K, et al. 2015. "The Relationship of Educational Attainment with Pulmonary Emphysema and Airway Wall Thickness." Annals of the American Thoracic Society 12 (6) doi:10.1513/AnnalsATS.201410-485OC
Sharma Amitabh, Menche Jörg, Huang C Chris, Ort Tatiana, Zhou Xiaobo, et al. 2015. "A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma." Human molecular genetics 24 (11) doi:10.1093/hmg/ddv001
Jaramillo Joshua D, Wilson Carla, Stinson Douglas S, Stinson Douglas J, Lynch David A, et al. 2015. "Reduced Bone Density and Vertebral Fractures in Smokers. Men and COPD Patients at Increased Risk." Annals of the American Thoracic Society 12 (5) doi:10.1513/AnnalsATS.201412-591OC
Wan Emily S, Qiu Weiliang, Morrow Jarrett, Beaty Terri H, Hetmanski Jacqueline, et al. 2015. "Genome-wide site-specific differential methylation in the blood of individuals with Klinefelter syndrome." Molecular reproduction and development 82 (5) doi:10.1002/mrd.22483
Lee Jin Hwa, Cho Michael H, Hersh Craig P, McDonald Merry-Lynn N, Wells J Michael, et al. 2015. "IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 52 (3) doi:10.1165/rcmb.2014-0210OC
Kim Victor, Crapo James, Zhao Huaqing, Jones Paul W, Silverman Edwin K, et al. 2015. "Comparison between an alternative and the classic definition of chronic bronchitis in COPDGene." Annals of the American Thoracic Society 12 (3) doi:10.1513/AnnalsATS.201411-518OC
Rennard Stephen I, Locantore Nicholas, Delafont Bruno, Tal-Singer Ruth, Silverman Edwin K, et al. 2015. "Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis." Annals of the American Thoracic Society 12 (3) doi:10.1513/AnnalsATS.201403-125OC
Chen Wei, Brehm John M, Manichaikul Ani, Cho Michael H, Boutaoui Nadia, et al. 2015. "A genome-wide association study of chronic obstructive pulmonary disease in Hispanics." Annals of the American Thoracic Society 12 (3) doi:10.1513/AnnalsATS.201408-380OC
Castaldi Peter J, Cho Michael H, Zhou Xiaobo, Qiu Weiliang, Mcgeachie Michael, et al. 2015. "Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci." Human molecular genetics 24 (4) doi:10.1093/hmg/ddu525
Agustí Alvar, Antó Josep Maria, Auffray Charles, Barbé Ferran, Barreiro Esther, et al. 2015. "Personalized respiratory medicine: exploring the horizon, addressing the issues. Summary of a BRN-AJRCCM workshop held in Barcelona on June 12, 2014." American journal of respiratory and critical care medicine 191 (4) doi:10.1164/rccm.201410-1935PP
Stanley Susan E, Chen Julian J L, Podlevsky Joshua D, Alder Jonathan K, Hansel Nadia N, et al. 2015. "Telomerase mutations in smokers with severe emphysema." The Journal of clinical investigation 125 (2) doi:10.1172/JCI78554
Lutz Sharon M, Cho Michael H, Young Kendra, Hersh Craig P, Castaldi Peter J, et al. 2015. "A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry." BMC genetics 16 doi:10.1186/s12863-015-0299-4
Dijkstra Akkelies E, Smolonska Joanna, van den Berge Maarten, Wijmenga Ciska, Zanen Pieter, et al. 2015. "Correction: Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study." PloS one 10 (5) doi:10.1371/journal.pone.0129524
Kliment Corrine R, Araki Tetsuro, Doyle Tracy J, Gao Wei, Dupuis Josée, et al. 2015. "A comparison of visual and quantitative methods to identify interstitial lung abnormalities." BMC pulmonary medicine 15 doi:10.1186/s12890-015-0124-x
Qiu Weiliang, Wan Emily, Morrow Jarrett, Cho Michael H, Crapo James D, et al. 2015. "The impact of genetic variation and cigarette smoke on DNA methylation in current and former smokers from the COPDGene study." Epigenetics 10 (11) doi:10.1080/15592294.2015.1106672
Lao Taotao, Glass Kimberly, Qiu Weiliang, Polverino Francesca, Gupta Kushagra, et al. 2015. "Haploinsufficiency of Hedgehog interacting protein causes increased emphysema induced by cigarette smoke through network rewiring." Genome medicine 7 (1) doi:10.1186/s13073-015-0137-3
Zhou Jin J, Cho Michael H, Lange Christoph, Lutz Sharon, Silverman Edwin K, Laird Nan M 2015. "Integrating Multiple Correlated Phenotypes for Genetic Association Analysis by Maximizing Heritability." Human heredity 79 (2) doi:10.1159/000381641
Barnes Peter J, Burney Peter G J, Silverman Edwin K, Celli Bartolome R, Vestbo Jørgen, et al. 2015. "Chronic obstructive pulmonary disease." Nature reviews. Disease primers 1 doi:10.1038/nrdp.2015.76

2014

Staples Jeffrey, Qiao Dandi, Cho Michael H, Silverman Edwin K, Nickerson Deborah A, Below Jennifer E 2014. "PRIMUS: rapid reconstruction of pedigrees from genome-wide estimates of identity by descent." American journal of human genetics 95 (5) doi:10.1016/j.ajhg.2014.10.005
Parker Margaret M, Foreman Marilyn G, Abel Haley J, Mathias Rasika A, Hetmanski Jacqueline B, et al. 2014. "Admixture mapping identifies a quantitative trait locus associated with FEV1/FVC in the COPDGene Study." Genetic epidemiology 38 (7) doi:10.1002/gepi.21847
McDonald Merry-Lynn N, Cho Michael H, Sørheim Inga-Cecilie, Lutz Sharon M, Castaldi Peter J, et al. 2014. "Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 51 (5) doi:10.1165/rcmb.2014-0135OC
Bhatt Surya P, Wells James M, Kim Victor, Criner Gerard J, Hersh Craig P, et al. 2014. "Radiological correlates and clinical implications of the paradoxical lung function response to β₂ agonists: an observational study." The Lancet. Respiratory medicine 2 (11) doi:10.1016/S2213-2600(14)70185-7
Hobbs Brian D, Foreman Marilyn G, Bowler Russell, Jacobson Francine, Make Barry J, et al. 2014. "Pneumothorax risk factors in smokers with and without chronic obstructive pulmonary disease." Annals of the American Thoracic Society 11 (9) doi:10.1513/AnnalsATS.201405-224OC
Diaz Alejandro A, Hardin Megan E, Come Carolyn E, San José Estépar Raúl, Ross James C, et al. 2014. "Childhood-onset asthma in smokers. association between CT measures of airway size, lung function, and chronic airflow obstruction." Annals of the American Thoracic Society 11 (9) doi:10.1513/AnnalsATS.201403-095OC
Marchetti Nathaniel, Garshick Eric, Kinney Gregory L, McKenzie Alex, Stinson Douglas, et al. 2014. "Association between occupational exposure and lung function, respiratory symptoms, and high-resolution computed tomography imaging in COPDGene." American journal of respiratory and critical care medicine 190 (7) doi:10.1164/rccm.201403-0493OC
Bowler Russell P, Kim Victor, Regan Elizabeth, Williams André A A, Santorico Stephanie A, et al. 2014. "Prediction of acute respiratory disease in current and former smokers with and without COPD." Chest 146 (4) doi:10.1378/chest.13-2946
Lee Jin Hwa, Cho Michael H, McDonald Merry-Lynn N, Hersh Craig P, Castaldi Peter J, et al. 2014. "Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene." Respiratory medicine 108 (10) doi:10.1016/j.rmed.2014.07.018
Black-Shinn Jennifer L, Kinney Gregory L, Wise Anastasia L, Regan Elizabeth A, Make Barry, et al. 2014. "Cardiovascular disease is associated with COPD severity and reduced functional status and quality of life." COPD 11 (5) doi:10.3109/15412555.2014.898029
Castaldi Peter J, Cho Michael H, San José Estépar Raúl, McDonald Merry-Lynn N, Laird Nan, et al. 2014. "Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns." American journal of respiratory and critical care medicine 190 (4) doi:10.1164/rccm.201403-0569OC
Hardin Megan, Cho Michael, McDonald Merry-Lynn, Beaty Terri, Ramsdell Joe, et al. 2014. "The clinical and genetic features of COPD-asthma overlap syndrome." The European respiratory journal 44 (2) doi:10.1183/09031936.00216013
Kim Woo Jin, Lim Myoung Nam, Hong Yoonki, Silverman Edwin K, Lee Ji-Hyun, et al. 2014. "Association of lung function genes with chronic obstructive pulmonary disease." Lung 192 (4) doi:10.1007/s00408-014-9579-4
Williams Michelle C, Murchison John T, Edwards Lisa D, Agustí Alvar, Bakke Per, et al. 2014. "Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality." Thorax 69 (8) doi:10.1136/thoraxjnl-2012-203151
Faner Rosa, Tal-Singer Ruth, Riley John H, Celli Bartolomé, Vestbo Jørgen, et al. 2014. "Lessons from ECLIPSE: a review of COPD biomarkers." Thorax 69 (7) doi:10.1136/thoraxjnl-2013-204778
Vestbo Jørgen, Agusti Alvar, Wouters Emiel F M, Bakke Per, Calverley Peter M A, et al. 2014. "Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team." American journal of respiratory and critical care medicine 189 (9) doi:10.1164/rccm.201311-2006PP
Castaldi Peter J, Dy Jennifer, Ross James, Chang Yale, Washko George R, et al. 2014. "Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema." Thorax 69 (5) doi:10.1136/thoraxjnl-2013-203601
Cho Michael H, McDonald Merry-Lynn N, Zhou Xiaobo, Mattheisen Manuel, Castaldi Peter J, et al. 2014. "Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis." The Lancet. Respiratory medicine 2 (3) doi:10.1016/S2213-2600(14)70002-5
McDonald Merry-Lynn N, Diaz Alejandro A, Ross James C, San Jose Estepar Raul, Zhou Linfu, et al. 2014. "Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study." Annals of the American Thoracic Society 11 (3) doi:10.1513/AnnalsATS.201307-229OC
Martinez Carlos H, Kim Victor, Chen Yahong, Kazerooni Ella A, Murray Susan, et al. 2014. "The clinical impact of non-obstructive chronic bronchitis in current and former smokers." Respiratory medicine 108 (3) doi:10.1016/j.rmed.2013.11.003
Molloy Kevin, Hersh Craig P, Morris Valerie B, Carroll Tomás P, O'Connor Catherine A, et al. 2014. "Clarification of the risk of chronic obstructive pulmonary disease in α1-antitrypsin deficiency PiMZ heterozygotes." American journal of respiratory and critical care medicine 189 (4) doi:10.1164/rccm.201311-1984OC
Manichaikul Ani, Hoffman Eric A, Smolonska Joanna, Gao Wei, Cho Michael H, et al. 2014. "Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study." American journal of respiratory and critical care medicine 189 (4) doi:10.1164/rccm.201306-1061OC
Kinney Gregory L, Black-Shinn Jennifer L, Wan Emily S, Make Barry, Regan Elizabeth, et al. 2014. "Pulmonary function reduction in diabetes with and without chronic obstructive pulmonary disease." Diabetes care 37 (2) doi:10.2337/dc13-1435
Qiao Dandi, Cho Michael H, Fier Heide, Bakke Per S, Gulsvik Amund, et al. 2014. "On the simultaneous association analysis of large genomic regions: a massive multi-locus association test." Bioinformatics (Oxford, England) 30 (2) doi:10.1093/bioinformatics/btt654
Dijkstra Akkelies E, Smolonska Joanna, van den Berge Maarten, Wijmenga Ciska, Zanen Pieter, et al. 2014. "Susceptibility to chronic mucus hypersecretion, a genome wide association study." PloS one 9 (4) doi:10.1371/journal.pone.0091621
Lee Jin Hwa, McDonald Merry-Lynn N, Cho Michael H, Wan Emily S, Castaldi Peter J, et al. 2014. "DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease." Respiratory research 15 doi:10.1186/s12931-014-0097-y
Wan Emily S, Castaldi Peter J, Cho Michael H, Hokanson John E, Regan Elizabeth A, et al. 2014. "Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene." Respiratory research 15 doi:10.1186/s12931-014-0089-y
McDonald Merry-Lynn Noelle, Mattheisen Manuel, Cho Michael H, Liu Yang-Yu, Harshfield Benjamin, et al. 2014. "Beyond GWAS in COPD: probing the landscape between gene-set associations, genome-wide associations and protein-protein interaction networks." Human heredity 78 (3-4) doi:10.1159/000365589
Kim Victor, Davey Adam, Comellas Alejandro P, Han Meilan K, Washko George, et al. 2014. "Clinical and computed tomographic predictors of chronic bronchitis in COPD: a cross sectional analysis of the COPDGene study." Respiratory research 15 doi:10.1186/1465-9921-15-52
Martinez Carlos H, Okajima Yuka, Murray Susan, Washko George R, Martinez Fernando J, et al. 2014. "Impact of self-reported gastroesophageal reflux disease in subjects from COPDGene cohort." Respiratory research 15 doi:10.1186/1465-9921-15-62
Chu Jen-hwa, Hersh Craig P, Castaldi Peter J, Cho Michael H, Raby Benjamin A, et al. 2014. "Analyzing networks of phenotypes in complex diseases: methodology and applications in COPD." BMC systems biology 8 doi:10.1186/1752-0509-8-78
Kim Song Soo, Yagihashi Kunihiro, Stinson Douglas S, Zach Jordan A, McKenzie Alexander S, et al. 2014. "Visual Assessment of CT Findings in Smokers With Nonobstructed Spirometric Abnormalities in The COPDGene(®) Study." Chronic obstructive pulmonary diseases (Miami, Fla.) 1 (1) doi:10.15326/jcopdf.1.1.2013.0001#sthash.L0atdpjM.dpuf
Kim Victor, Desai Parag, Newell John D, Make Barry J, Washko George R, et al. 2014. "Airway wall thickness is increased in COPD patients with bronchodilator responsiveness." Respiratory research 15 doi:10.1186/s12931-014-0084-3
Lee Jin Hwa, Cho Michael H, Hersh Craig P, McDonald Merry-Lynn N, Crapo James D, et al. 2014. "Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease." Respiratory research 15 doi:10.1186/s12931-014-0113-2
Menche Jörg, Sharma Amitabh, Cho Michael H, Mayer Ruth J, Rennard Stephen I, et al. 2014. "A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease." BMC systems biology 8 Suppl 2 doi:10.1186/1752-0509-8-S2-S8
Kim Victor, Goel Nishant, Gangar Jinal, Zhao Huaqing, Ciccolella David E, et al. 2014. "Risk Factors for Venous Thromboembolism in Chronic Obstructive Pulmonary Disease." Chronic obstructive pulmonary diseases (Miami, Fla.) 1 (2) doi:10.15326/jcopdf.1.2.2014.0133#sthash.pvwPnxaI.dpuf
Putcha Nirupama, Han Meilan K, Martinez Carlos H, Foreman Marilyn G, Anzueto Antonio R, et al. 2014. "Comorbidities of COPD have a major impact on clinical outcomes, particularly in African Americans." Chronic obstructive pulmonary diseases (Miami, Fla.) 1 (1) doi:10.15326/jcopdf.1.1.2014.0112
Hersh Craig P, Make Barry J, Lynch David A, Barr R Graham, Bowler Russell P, et al. 2014. "Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus." BMC pulmonary medicine 14 doi:10.1186/1471-2466-14-164
Putcha Nirupama, Puhan Milo A, Drummond M Bradley, Han MeiLan K, Regan Elizabeth A, et al. 2014. "A simplified score to quantify comorbidity in COPD." PloS one 9 (12) doi:10.1371/journal.pone.0114438
Glass Kimberly, Quackenbush John, Silverman Edwin K, Celli Bartolome, Rennard Stephen I, et al. 2014. "Sexually-dimorphic targeting of functionally-related genes in COPD." BMC systems biology 8 doi:10.1186/s12918-014-0118-y

2013

Ross James C, Kindlmann Gordon L, Okajima Yuka, Hatabu Hiroto, Díaz Alejandro A, et al. 2013. "Pulmonary lobe segmentation based on ridge surface sampling and shape model fitting." Medical physics 40 (12) doi:10.1118/1.4828782
Lam Hilaire C, Cloonan Suzanne M, Bhashyam Abhiram R, Haspel Jeffery A, Singh Anju, et al. 2013. "Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction." The Journal of clinical investigation 123 (12) doi:10.1172/JCI69636
Castaldi Peter J, San José Estépar Raúl, Mendoza Carlos S, Hersh Craig P, Laird Nan, et al. 2013. "Distinct quantitative computed tomography emphysema patterns are associated with physiology and function in smokers." American journal of respiratory and critical care medicine 188 (9) doi:10.1164/rccm.201305-0873OC
Cheng Donavan T, Kim Deog Kyeom, Cockayne Debra A, Belousov Anton, Bitter Hans, et al. 2013. "Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 188 (8) doi:10.1164/rccm.201302-0247OC
Zhou Jin J, Cho Michael H, Castaldi Peter J, Hersh Craig P, Silverman Edwin K, Laird Nan M 2013. "Heritability of chronic obstructive pulmonary disease and related phenotypes in smokers." American journal of respiratory and critical care medicine 188 (8) doi:10.1164/rccm.201302-0263OC
Miller Joy, Edwards Lisa D, Agustí Alvar, Bakke Per, Calverley Peter M A, et al. 2013. "Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort." Respiratory medicine 107 (9) doi:10.1016/j.rmed.2013.05.001
Zhou Xiaobo, Qiu Weiliang, Sathirapongsasuti J Fah, Cho Michael H, Mancini John D, et al. 2013. "Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cells." Genomics 101 (5) doi:10.1016/j.ygeno.2013.02.010
Coxson Harvey O, Dirksen Asger, Edwards Lisa D, Yates Julie C, Agusti Alvar, et al. 2013. "The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: a prospective analysis from the ECLIPSE study." The Lancet. Respiratory medicine 1 (2) doi:10.1016/S2213-2600(13)70006-7
Siedlinski Mateusz, Tingley Dustin, Lipman Peter J, Cho Michael H, Litonjua Augusto A, et al. 2013. "Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility." Human genetics 132 (4) doi:10.1007/s00439-012-1262-3
Li Chenggang, Zhou Xiaobo, Sun Yang, Zhang Erik, Mancini John D, et al. 2013. "Faslodex Inhibits Estradiol-induced ECM Dynamics and Lung Metastasis in a Model of LAM." American journal of respiratory cell and molecular biology doi:10.1165/rcmb.2012-0476OC
Han MeiLan K, Muellerova Hana, Curran-Everett Douglas, Dransfield Mark T, Washko George R, et al. 2013. "GOLD 2011 disease severity classification in COPDGene: a prospective cohort study." The Lancet. Respiratory medicine 1 (1) doi:10.1016/S2213-2600(12)70044-9
Diaz Alejandro A, Han Meilan K, Come Carolyn E, San José Estépar Raúl, Ross James C, et al. 2013. "Effect of emphysema on CT scan measures of airway dimensions in smokers." Chest 143 (3) doi:10.1378/chest.12-0039
Polkey Michael I, Spruit Martijn A, Edwards Lisa D, Watkins Michael L, Pinto-Plata Victor, et al. 2013. "Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization." American journal of respiratory and critical care medicine 187 (4) doi:10.1164/rccm.201209-1596OC
Hansel Nadia N, Washko George R, Foreman Marilyn G, Han MeiLan K, Hoffman Eric A, et al. 2013. "Racial differences in CT phenotypes in COPD." COPD 10 (1) doi:10.3109/15412555.2012.727921
Rutten Erica P A, Calverley Peter M A, Casaburi Richard, Agusti Alvar, Bakke Per, et al. 2013. "Changes in body composition in patients with chronic obstructive pulmonary disease: do they influence patient-related outcomes?" Annals of nutrition & metabolism 63 (3) doi:10.1159/000353211
Hersh Craig P, Washko George R, Estépar Raúl San José, Lutz Sharon, Friedman Paul J, et al. 2013. "Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD." Respiratory research 14 doi:10.1186/1465-9921-14-42
Himes Blanca E, Sheppard Keith, Berndt Annerose, Leme Adriana S, Myers Rachel A, et al. 2013. "Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene." PloS one 8 (2) doi:10.1371/journal.pone.0056179
Aminuddin Farzian, Hackett Tillie-Louise, Stefanowicz Dorota, Saferali Aabida, Paré Peter D, et al. 2013. "Nitric oxide synthase polymorphisms, gene expression and lung function in chronic obstructive pulmonary disease." BMC pulmonary medicine 13 doi:10.1186/1471-2466-13-64
Oh Yeon-Mok, Bhome Arvind B, Boonsawat Watchara, Gunasekera Kirthi Dias, Madegedara Dushantha, et al. 2013. "Characteristics of stable chronic obstructive pulmonary disease patients in the pulmonology clinics of seven Asian cities." International journal of chronic obstructive pulmonary disease 8 doi:

2012

Kim Deog Kyeom, Cho Michael H, Hersh Craig P, Lomas David A, Miller Bruce E, et al. 2012. "Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 186 (12) doi:10.1164/rccm.201206-1013OC
Fier Heide, Won Sungho, Prokopenko Dmitry, AlChawa Taofik, Ludwig Kerstin U, et al. 2012. "'Location, Location, Location': a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate." Bioinformatics (Oxford, England) 28 (23) doi:10.1093/bioinformatics/bts568
Zach Jordan Alexander, Newell John D, Schroeder Joyce, Murphy James R, Curran-Everett Douglas, et al. 2012. "Quantitative computed tomography of the lungs and airways in healthy nonsmoking adults." Investigative radiology 47 (10) doi:10.1097/RLI.0b013e318262292e
Wilk Jemma B, Shrine Nick R G, Loehr Laura R, Zhao Jing Hua, Manichaikul Ani, et al. 2012. "Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction." American journal of respiratory and critical care medicine 186 (7) doi:10.1164/rccm.201202-0366OC
Wells J Michael, Washko George R, Han MeiLan K, Abbas Naseer, Nath Hrudaya, et al. 2012. "Pulmonary arterial enlargement and acute exacerbations of COPD." The New England journal of medicine 367 (10) doi:10.1056/NEJMoa1203830
Hardin Megan, Zielinski Jan, Wan Emily S, Hersh Craig P, Castaldi Peter J, et al. 2012. "CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland." American journal of respiratory cell and molecular biology 47 (2) doi:10.1165/rcmb.2012-0011OC
Albert Paul, Agusti Alvar, Edwards Lisa, Tal-Singer Ruth, Yates Julie, et al. 2012. "Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease." Thorax 67 (8) doi:10.1136/thoraxjnl-2011-201458
Silverman Edwin K, Loscalzo Joseph 2012. "Network medicine approaches to the genetics of complex diseases." Discovery medicine 14 (75) doi:
Fardo David W, Liu Jinze, Demeo Dawn L, Silverman Edwin K, Vansteelandt Stijn 2012. "Gene-environment interaction testing in family-based association studies with phenotypically ascertained samples: a causal inference approach." Biostatistics (Oxford, England) 13 (3) doi:10.1093/biostatistics/kxr035
Barr R Graham, Berkowitz Eugene A, Bigazzi Francesca, Bode Frederick, Bon Jessica, et al. 2012. "A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation." COPD 9 (2) doi:10.3109/15412555.2012.654923
Doyle Tracy J, Washko George R, Fernandez Isis E, Nishino Mizuki, Okajima Yuka, et al. 2012. "Interstitial lung abnormalities and reduced exercise capacity." American journal of respiratory and critical care medicine 185 (7) doi:10.1164/rccm.201109-1618OC
Zhou Xiaobo, Baron Rebecca M, Hardin Megan, Cho Michael H, Zielinski Jan, et al. 2012. "Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP." Human molecular genetics 21 (6) doi:10.1093/hmg/ddr569
Xu Jin-Fu, Washko George R, Nakahira Kiichi, Hatabu Hiroto, Patel Avignat S, et al. 2012. "Statins and pulmonary fibrosis: the potential role of NLRP3 inflammasome activation." American journal of respiratory and critical care medicine 185 (5) doi:10.1164/rccm.201108-1574OC
Spruit Martijn A, Polkey Michael I, Celli Bartolome, Edwards Lisa D, Watkins Michael L, et al. 2012. "Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease." Journal of the American Medical Directors Association 13 (3) doi:10.1016/j.jamda.2011.06.009
Diaz Alejandro A, Come Carolyn E, Ross James C, San José Estépar Raúl, Han Meilan K, et al. 2012. "Association between airway caliber changes with lung inflation and emphysema assessed by volumetric CT scan in subjects with COPD." Chest 141 (3) doi:10.1378/chest.11-1026
Cho Michael H, Castaldi Peter J, Wan Emily S, Siedlinski Mateusz, Hersh Craig P, et al. 2012. "A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13." Human molecular genetics 21 (4) doi:10.1093/hmg/ddr524
Swift Irene, Satti Aditi, Kim Victor, Make Barry J, Newell John, et al. 2012. "Demographic, physiologic and radiographic characteristics of COPD patients taking chronic systemic corticosteroids." COPD 9 (1) doi:10.3109/15412555.2011.634454
Estépar Raúl San José, Ross James C, Kindlmann Gordon L, Diaz Alejandro, Okajima Yuka, et al. 2012. "AUTOMATIC AIRWAY ANALYSIS FOR GENOME-WIDE ASSOCIATION STUDIES IN COPD." Proceedings / IEEE International Symposium on Biomedical Imaging: from nano to macro. IEEE International Symposium on Biomedical Imaging doi:10.1109/ISBI.2012.6235848
Kim Woo Jin, Wood Alice M, Barker Alan F, Brantly Mark L, Campbell Edward J, et al. 2012. "Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency." Respiratory research 13 doi:10.1186/1465-9921-13-16
Agustí Alvar, Edwards Lisa D, Rennard Stephen I, MacNee William, Tal-Singer Ruth, et al. 2012. "Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype." PloS one 7 (5) doi:10.1371/journal.pone.0037483

2011

Hoffmann Thomas J, Vansteelandt Stijn, Lange Christoph, Silverman Edwin K, DeMeo Dawn L, Laird Nan M 2011. "Combining disease models to test for gene-environment interaction in nuclear families." Biometrics 67 (4) doi:10.1111/j.1541-0420.2011.01581.x
Brehm John M, Hagiwara Koichi, Tesfaigzi Yohannes, Bruse Shannon, Mariani Thomas J, et al. 2011. "Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease." Thorax 66 (12) doi:10.1136/thoraxjnl-2011-200017
Castaldi Peter J, Cho Michael H, Litonjua Augusto A, Bakke Per, Gulsvik Amund, et al. 2011. "The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility." American journal of respiratory cell and molecular biology 45 (6) doi:10.1165/rcmb.2011-0055OC
Siedlinski Mateusz, Cho Michael H, Bakke Per, Gulsvik Amund, Lomas David A, et al. 2011. "Genome-wide association study of smoking behaviours in patients with COPD." Thorax 66 (10) doi:10.1136/thoraxjnl-2011-200154
Han Meilan K, Kazerooni Ella A, Lynch David A, Liu Lyrica X, Murray Susan, et al. 2011. "Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes." Radiology 261 (1) doi:10.1148/radiol.11110173
Vestbo Jørgen, Edwards Lisa D, Scanlon Paul D, Yates Julie C, Agusti Alvar, et al. 2011. "Changes in forced expiratory volume in 1 second over time in COPD." The New England journal of medicine 365 (13) doi:10.1056/NEJMoa1105482
Himes Blanca E, Klanderman Barbara, Ziniti John, Senter-Sylvia Jody, Soto-Quiros Manuel E, et al. 2011. "Association of SERPINE2 with asthma." Chest 140 (3) doi:10.1378/chest.10-2973
Kim Victor, Han Meilan K, Vance Gwendolyn B, Make Barry J, Newell John D, et al. 2011. "The chronic bronchitic phenotype of COPD: an analysis of the COPDGene Study." Chest 140 (3) doi:10.1378/chest.10-2948
Foreman Marilyn G, Zhang Lening, Murphy James, Hansel Nadia N, Make Barry, et al. 2011. "Early-onset chronic obstructive pulmonary disease is associated with female sex, maternal factors, and African American race in the COPDGene Study." American journal of respiratory and critical care medicine 184 (4) doi:10.1164/rccm.201011-1928OC
Hersh Craig P, Hokanson John E, Lynch David A, Washko George R, Make Barry J, et al. 2011. "Family history is a risk factor for COPD." Chest 140 (2) doi:10.1378/chest.10-2761
Kim Deog Kyeom, Jacobson Francine L, Washko George R, Casaburi Richard, Make Barry J, et al. 2011. "Clinical and radiographic correlates of hypoxemia and oxygen therapy in the COPDGene study." Respiratory medicine 105 (8) doi:10.1016/j.rmed.2011.02.015
Wan Emily S, Cho Michael H, Boutaoui Nadia, Klanderman Barbara J, Sylvia Jody S, et al. 2011. "Genome-wide association analysis of body mass in chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 45 (2) doi:10.1165/rcmb.2010-0294OC
Lipman Peter J, Cho Michael H, Bakke Per, Gulsvik Amund, Kong Xiangyang, et al. 2011. "On the follow-up of genome-wide association studies: an overall test for the most promising SNPs." Genetic epidemiology 35 (5) doi:10.1002/gepi.20578
Wan Emily S, Hokanson John E, Murphy James R, Regan Elizabeth A, Make Barry J, et al. 2011. "Clinical and radiographic predictors of GOLD-unclassified smokers in the COPDGene study." American journal of respiratory and critical care medicine 184 (1) doi:10.1164/rccm.201101-0021OC
Hersh Craig P, Silverman Edwin K, Gascon Jody, Bhattacharya Soumyaroop, Klanderman Barbara J, et al. 2011. "SOX5 is a candidate gene for chronic obstructive pulmonary disease susceptibility and is necessary for lung development." American journal of respiratory and critical care medicine 183 (11) doi:10.1164/rccm.201010-1751OC
Sin Don D, Miller Bruce E, Duvoix Annelyse, Man S F Paul, Zhang Xuekui, et al. 2011. "Serum PARC/CCL-18 concentrations and health outcomes in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 183 (9) doi:10.1164/rccm.201008-1220OC
Wan Emily S, DeMeo Dawn L, Hersh Craig P, Shapiro Steven D, Rosiello Richard A, et al. 2011. "Clinical predictors of frequent exacerbations in subjects with severe chronic obstructive pulmonary disease (COPD)." Respiratory medicine 105 (4) doi:10.1016/j.rmed.2010.11.015
Washko George R, Hunninghake Gary M, Fernandez Isis E, Nishino Mizuki, Okajima Yuka, et al. 2011. "Lung volumes and emphysema in smokers with interstitial lung abnormalities." The New England journal of medicine 364 (10) doi:10.1056/NEJMoa1007285
Yamashiro Tsuneo, San José Estépar Raúl, Matsuoka Shin, Bartholmai Brian J, Ross James C, et al. 2011. "Intrathoracic tracheal volume and collapsibility on inspiratory and end-expiratory ct scans correlations with lung volume and pulmonary function in 85 smokers." Academic radiology 18 (3) doi:10.1016/j.acra.2010.11.005
Foreman Marilyn G, Kong Xiangyang, DeMeo Dawn L, Pillai Sreekumar G, Hersh Craig P, et al. 2011. "Polymorphisms in surfactant protein-D are associated with chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 44 (3) doi:10.1165/rcmb.2009-0360OC
Yamashiro Tsuneo, Matsuoka Shin, Estépar Raúl San José, Bartholmai Brian J, Diaz Alejandro, et al. 2011. "Kurtosis and skewness of density histograms on inspiratory and expiratory CT scans in smokers." COPD 8 (1) doi:10.3109/15412555.2010.541537
Kong Xiangyang, Cho Michael H, Anderson Wayne, Coxson Harvey O, Muller Nestor, et al. 2011. "Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema." American journal of respiratory and critical care medicine 183 (1) doi:10.1164/rccm.201004-0541OC
Kim Deog Kyeom, Hersh Craig P, Washko George R, Hokanson John E, Lynch David A, et al. 2011. "Epidemiology, radiology, and genetics of nicotine dependence in COPD." Respiratory research 12 doi:10.1186/1465-9921-12-9
Matsuoka Shin, Yamashiro Tsuneo, Diaz Alejandro, Estépar Raúl San José, Ross James C, et al. 2011. "The relationship between small pulmonary vascular alteration and aortic atherosclerosis in chronic obstructive pulmonary disease: quantitative CT analysis." Academic radiology 18 (1) doi:10.1016/j.acra.2010.08.013
Qiu Weiliang, Cho Michael H, Riley John H, Anderson Wayne H, Singh Dave, et al. 2011. "Genetics of sputum gene expression in chronic obstructive pulmonary disease." PloS one 6 (9) doi:10.1371/journal.pone.0024395
Dickens Jennifer A, Miller Bruce E, Edwards Lisa D, Silverman Edwin K, Lomas David A, Tal-Singer Ruth 2011. "COPD association and repeatability of blood biomarkers in the ECLIPSE cohort." Respiratory research 12 doi:10.1186/1465-9921-12-146
Hardin Megan, Silverman Edwin K, Barr R Graham, Hansel Nadia N, Schroeder Joyce D, et al. 2011. "The clinical features of the overlap between COPD and asthma." Respiratory research 12 doi:10.1186/1465-9921-12-127
Bhattacharya Soumyaroop, Tyagi Shivraj, Srisuma Sorachai, Demeo Dawn L, Shapiro Steven D, et al. 2011. "Peripheral blood gene expression profiles in COPD subjects." Journal of clinical bioinformatics 1 (1) doi:10.1186/2043-9113-1-12

2010

Pillai Sreekumar G, Kong Xiangyang, Edwards Lisa D, Cho Michael H, Anderson Wayne H, et al. 2010. "Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 182 (12) doi:10.1164/rccm.201002-0151OC
Ingebrigtsen Truls, Thomsen Simon F, Vestbo Jørgen, van der Sluis Sophie, Kyvik Kirsten O, et al. 2010. "Genetic influences on Chronic Obstructive Pulmonary Disease - a twin study." Respiratory medicine 104 (12) doi:10.1016/j.rmed.2010.05.004
Sørheim Inga-Cecilie, Bakke Per, Gulsvik Amund, Pillai Sreekumar G, Johannessen Ane, et al. 2010. "α₁-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts." Chest 138 (5) doi:10.1378/chest.10-0746
Diaz Alejandro A, Valim Clarissa, Yamashiro Tsuneo, Estépar Raúl San José, Ross James C, et al. 2010. "Airway count and emphysema assessed by chest CT imaging predicts clinical outcome in smokers." Chest 138 (4) doi:10.1378/chest.10-0542
Eisner Mark D, Anthonisen Nicholas, Coultas David, Kuenzli Nino, Perez-Padilla Rogelio, et al. 2010. "An official American Thoracic Society public policy statement: Novel risk factors and the global burden of chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 182 (5) doi:10.1164/rccm.200811-1757ST
Han MeiLan K, Agusti Alvar, Calverley Peter M, Celli Bartolome R, Criner Gerard, et al. 2010. "Chronic obstructive pulmonary disease phenotypes: the future of COPD." American journal of respiratory and critical care medicine 182 (5) doi:10.1164/rccm.200912-1843CC
Hersh Craig P, Pillai Sreekumar G, Zhu Guohua, Lomas David A, Bakke Per, et al. 2010. "Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene." American journal of respiratory and critical care medicine 182 (5) doi:10.1164/rccm.200910-1586OC
Yamashiro Tsuneo, Matsuoka Shin, Estépar Raúl San José, Dransfield Mark T, Diaz Alejandro, et al. 2010. "Quantitative assessment of bronchial wall attenuation with thin-section CT: An indicator of airflow limitation in chronic obstructive pulmonary disease." AJR. American journal of roentgenology 195 (2) doi:10.2214/AJR.09.3653
Diaz Alejandro A, Bartholmai Brian, San José Estépar Raúl, Ross James, Matsuoka Shin, et al. 2010. "Relationship of emphysema and airway disease assessed by CT to exercise capacity in COPD." Respiratory medicine 104 (8) doi:10.1016/j.rmed.2010.02.023
Sørheim Inga-Cecilie, Johannessen Ane, Gulsvik Amund, Bakke Per S, Silverman Edwin K, DeMeo Dawn L 2010. "Gender differences in COPD: are women more susceptible to smoking effects than men?" Thorax 65 (6) doi:10.1136/thx.2009.122002
Yamashiro Tsuneo, Matsuoka Shin, Bartholmai Brian J, San José Estépar Raúl, Ross James C, et al. 2010. "Collapsibility of lung volume by paired inspiratory and expiratory CT scans: correlations with lung function and mean lung density." Academic radiology 17 (4) doi:10.1016/j.acra.2009.11.004
Washko George R, Martinez Fernando J, Hoffman Eric A, Loring Stephen H, Estépar Raúl San José, et al. 2010. "Physiological and computed tomographic predictors of outcome from lung volume reduction surgery." American journal of respiratory and critical care medicine 181 (5) doi:10.1164/rccm.200906-0911OC
Wan Emily S, Pober Barbara R, Washko George R, Raby Benjamin A, Silverman Edwin K 2010. "Pulmonary function and emphysema in Williams-Beuren syndrome." American journal of medical genetics. Part A 152A (3) doi:10.1002/ajmg.a.33300
Cho Michael H, Boutaoui Nadia, Klanderman Barbara J, Sylvia Jody S, Ziniti John P, et al. 2010. "Variants in FAM13A are associated with chronic obstructive pulmonary disease." Nature genetics 42 (3) doi:10.1038/ng.535
Regan Elizabeth A, Hokanson John E, Murphy James R, Make Barry, Lynch David A, et al. 2010. "Genetic epidemiology of COPD (COPDGene) study design." COPD 7 (1) doi:10.3109/15412550903499522
Matsuoka Shin, Washko George R, Yamashiro Tsuneo, Estepar Raul San Jose, Diaz Alejandro, et al. 2010. "Pulmonary hypertension and computed tomography measurement of small pulmonary vessels in severe emphysema." American journal of respiratory and critical care medicine 181 (3) doi:10.1164/rccm.200908-1189OC
Castaldi Peter J, Cho Michael H, Cohn Matthew, Langerman Fawn, Moran Sienna, et al. 2010. "The COPD genetic association compendium: a comprehensive online database of COPD genetic associations." Human molecular genetics 19 (3) doi:10.1093/hmg/ddp519
Ross James C, San José Estépar Rail, Kindlmann Gordon, Díaz Alejandro, Westin Carl-Fredrik, et al. 2010. "Automatic lung lobe segmentation using particles, thin plate splines, and maximum a posteriori estimation." Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention 13 (Pt 3) doi:
Cho Michael H, Washko George R, Hoffmann Thomas J, Criner Gerard J, Hoffman Eric A, et al. 2010. "Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation." Respiratory research 11 doi:10.1186/1465-9921-11-30
Himes Blanca E, Lasky-Su Jessica, Wu Ann C, Wilk Jemma B, Hunninghake Gary M, et al. 2010. "Asthma-susceptibility variants identified using probands in case-control and family-based analyses." BMC medical genetics 11 doi:10.1186/1471-2350-11-122
Agusti Alvar, Calverley Peter M A, Celli Bartolome, Coxson Harvey O, Edwards Lisa D, et al. 2010. "Characterisation of COPD heterogeneity in the ECLIPSE cohort." Respiratory research 11 doi:10.1186/1465-9921-11-122
Hoffmann Thomas J, Lange Christoph, Vansteelandt Stijn, Raby Benjamin A, DeMeo Dawn L, et al. 2010. "Parsing the effects of individual SNPs in candidate genes with family data." Human heredity 69 (2) doi:10.1159/000264447
Matsuoka Shin, Washko George R, Dransfield Mark T, Yamashiro Tsuneo, San Jose Estepar Raul, et al. 2010. "Quantitative CT measurement of cross-sectional area of small pulmonary vessel in COPD: correlations with emphysema and airflow limitation." Academic radiology 17 (1) doi:10.1016/j.acra.2009.07.022
Washko George R, Lynch David A, Matsuoka Shin, Ross James C, Umeoka Shigeaki, et al. 2010. "Identification of early interstitial lung disease in smokers from the COPDGene Study." Academic radiology 17 (1) doi:10.1016/j.acra.2009.07.016

2009

Hunninghake Gary M, Cho Michael H, Tesfaigzi Yohannes, Soto-Quiros Manuel E, Avila Lydiana, et al. 2009. "MMP12, lung function, and COPD in high-risk populations." The New England journal of medicine 361 (27) doi:10.1056/NEJMoa0904006
Camp Pat G, Coxson Harvey O, Levy Robert D, Pillai Sreekumar G, Anderson Wayne, et al. 2009. "Sex differences in emphysema and airway disease in smokers." Chest 136 (6) doi:10.1378/chest.09-0676
Yamashiro Tsuneo, Matsuoka Shin, Estépar Raúl San José, Diaz Alejandro, Newell John D, et al. 2009. "Quantitative airway assessment on computed tomography in patients with alpha1-antitrypsin deficiency." COPD 6 (6) doi:10.3109/15412550903341521
Won Sungho, Wilk Jemma B, Mathias Rasika A, O'Donnell Christopher J, Silverman Edwin K, et al. 2009. "On the analysis of genome-wide association studies in family-based designs: a universal, robust analysis approach and an application to four genome-wide association studies." PLoS genetics 5 (11) doi:10.1371/journal.pgen.1000741
DeMeo Dawn L, Mariani Thomas, Bhattacharya Soumyaroop, Srisuma Sorachai, Lange Christoph, et al. 2009. "Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene." American journal of human genetics 85 (4) doi:10.1016/j.ajhg.2009.09.004
Silverman Edwin K, Spira Avrum, Paré Peter D 2009. "Genetics and genomics of chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 6 (6) doi:10.1513/pats.200904-021DS
Hersh Craig P, Hansel Nadia N, Barnes Kathleen C, Lomas David A, Pillai Sreekumar G, et al. 2009. "Transforming growth factor-beta receptor-3 is associated with pulmonary emphysema." American journal of respiratory cell and molecular biology 41 (3) doi:10.1165/rcmb.2008-0427OC
Wan Emily S, Silverman Edwin K 2009. "Genetics of COPD and emphysema." Chest 136 (3) doi:10.1378/chest.09-0555
Kim Woo Jin, Silverman Edwin K, Hoffman Eric, Criner Gerard J, Mosenifar Zab, et al. 2009. "CT metrics of airway disease and emphysema in severe COPD." Chest 136 (2) doi:10.1378/chest.08-2858
Washko George R, Dransfield Mark T, Estépar Raúl San José, Diaz Alejandro, Matsuoka Shin, et al. 2009. "Airway wall attenuation: a biomarker of airway disease in subjects with COPD." Journal of applied physiology (Bethesda, Md. : 1985) 107 (1) doi:10.1152/japplphysiol.00216.2009
Rogers Angela J, Raby Benjamin A, Lasky-Su Jessica A, Murphy Amy, Lazarus Ross, et al. 2009. "Assessing the reproducibility of asthma candidate gene associations, using genome-wide data." American journal of respiratory and critical care medicine 179 (12) doi:10.1164/rccm.200812-1860OC
Zhu Guohua, Gulsvik Amund, Bakke Per, Ghatta Srinivas, Anderson Wayne, et al. 2009. "Association of TRPV4 gene polymorphisms with chronic obstructive pulmonary disease." Human molecular genetics 18 (11) doi:10.1093/hmg/ddp111
Cho Michael H, Ciulla Dawn M, Klanderman Barbara J, Hersh Craig P, Litonjua Augusto A, et al. 2009. "Analysis of exonic elastin variants in severe, early-onset chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 40 (6) doi:10.1165/rcmb.2008-0340OC
Himes Blanca E, Hunninghake Gary M, Baurley James W, Rafaels Nicholas M, Sleiman Patrick, et al. 2009. "Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene." American journal of human genetics 84 (5) doi:10.1016/j.ajhg.2009.04.006
Kim Woo Jin, Hersh Craig P, DeMeo Dawn L, Reilly John J, Silverman Edwin K 2009. "Genetic association analysis of COPD candidate genes with bronchodilator responsiveness." Respiratory medicine 103 (4) doi:10.1016/j.rmed.2008.10.025
Bhattacharya Soumyaroop, Srisuma Sorachai, Demeo Dawn L, Shapiro Steven D, Bueno Raphael, et al. 2009. "Molecular biomarkers for quantitative and discrete COPD phenotypes." American journal of respiratory cell and molecular biology 40 (3) doi:10.1165/rcmb.2008-0114OC
Pillai Sreekumar G, Ge Dongliang, Zhu Guohua, Kong Xiangyang, Shianna Kevin V, et al. 2009. "A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci." PLoS genetics 5 (3) doi:10.1371/journal.pgen.1000421
Wilk Jemma B, Chen Ting-Hsu, Gottlieb Daniel J, Walter Robert E, Nagle Michael W, et al. 2009. "A genome-wide association study of pulmonary function measures in the Framingham Heart Study." PLoS genetics 5 (3) doi:10.1371/journal.pgen.1000429
Castaldi Peter J, Hersh Craig P, Reilly John J, Silverman Edwin K 2009. "Genetic associations with hypoxemia and pulmonary arterial pressure in COPD." Chest 135 (3) doi:10.1378/chest.08-1993
Ross James C, Estépar Raúl San José, Díaz Alejandro, Westin Carl-Fredrik, Kikinis Ron, et al. 2009. "Lung extraction, lobe segmentation and hierarchical region assessment for quantitative analysis on high resolution computed tomography images." Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention 12 (Pt 2) doi:

2008

San José Estépar Raúl, Reilly John J, Silverman Edwin K, Washko George R 2008. "Three-dimensional airway measurements and algorithms." Proceedings of the American Thoracic Society 5 (9) doi:10.1513/pats.200809-104QC
Cho Michael H, Ciulla Dawn, Klanderman Barbara J, Raby Benjamin A, Silverman Edwin K 2008. "High-resolution melting curve analysis of genomic and whole-genome amplified DNA." Clinical chemistry 54 (12) doi:
Sandhaus Robert A, Turino Gerard, Stocks James, Strange Charlie, Trapnell Bruce C, et al. 2008. "alpha1-Antitrypsin augmentation therapy for PI*MZ heterozygotes: a cautionary note." Chest 134 (4) doi:10.1378/chest.08-0868
Patel Bipen D, Coxson Harvey O, Pillai Sreekumar G, Agustí Alvar G N, Calverley Peter M A, et al. 2008. "Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 178 (5) doi:10.1164/rccm.200801-059OC
Vansteelandt Stijn, Demeo Dawn L, Lasky-Su Jessica, Smoller Jordan W, Murphy Amy J, et al. 2008. "Testing and estimating gene-environment interactions in family-based association studies." Biometrics 64 (2) doi:10.1111/j.1541-0420.2007.00925.x
Hersh Craig P, DeMeo Dawn L, Silverman Edwin K 2008. "National Emphysema Treatment Trial state of the art: genetics of emphysema." Proceedings of the American Thoracic Society 5 (4) doi:10.1513/pats.200706-078ET
Lasky-Su Jessica, Lyon Helen N, Emilsson Valur, Heid Iris M, Molony Cliona, et al. 2008. "On the replication of genetic associations: timing can be everything!" American journal of human genetics 82 (4) doi:10.1016/j.ajhg.2008.01.018
Cho Michael H, Klanderman Barbara J, Litonjua Augusto A, Sparrow David, Silverman Edwin K, Raby Benjamin A 2008. "Folliculin mutations are not associated with severe COPD." BMC medical genetics 9 doi:10.1186/1471-2350-9-120
Demeo Dawn L, Campbell Edward J, Barker Alan F, Brantly Mark L, Eden Edward, et al. 2008. "IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency." American journal of respiratory cell and molecular biology 38 (1) doi:10.1165/rcmb.2007-0107OC

2007

Silverman Edwin K 2007. "Exacerbations in chronic obstructive pulmonary disease: do they contribute to disease progression?" Proceedings of the American Thoracic Society 4 (8) doi:10.1513/pats.200706-068TH
Hersh Craig P, Jacobson Francine L, Gill Ritu, Silverman Edwin K 2007. "Computed tomography phenotypes in severe, early-onset chronic obstructive pulmonary disease." COPD 4 (4) doi:10.1080/15412550701601274
Demeo Dawn L, Sandhaus Robert A, Barker Alan F, Brantly Mark L, Eden Edward, et al. 2007. "Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiency." Thorax 62 (9) doi:10.1136/thx.2006.075846
Wang Florence T, Hu Howard, Schwartz Joel, Weuve Jennifer, Spiro Avron S, et al. 2007. "Modifying effects of the HFE polymorphisms on the association between lead burden and cognitive decline." Environmental health perspectives 115 (8) doi:10.1289/ehp.9855
Raby Benjamin A, Klanderman Barbara, Murphy Amy, Mazza Salvatore, Camargo Carlos A, et al. 2007. "A common mitochondrial haplogroup is associated with elevated total serum IgE levels." The Journal of allergy and clinical immunology 120 (2) doi:10.1016/j.jaci.2007.05.029
Zhu Guohua, Warren Liling, Aponte Jennifer, Gulsvik Amund, Bakke Per, et al. 2007. "The SERPINE2 gene is associated with chronic obstructive pulmonary disease in two large populations." American journal of respiratory and critical care medicine 176 (2) doi:10.1164/rccm.200611-1723OC
DeMeo Dawn L, Hersh Craig P, Hoffman Eric A, Litonjua Augusto A, Lazarus Ross, et al. 2007. "Genetic determinants of emphysema distribution in the national emphysema treatment trial." American journal of respiratory and critical care medicine 176 (1) doi:10.1164/rccm.200612-1797OC
Hunninghake Gary M, Soto-Quirós Manuel E, Avila Lydiana, Su Jessica, Murphy Amy, et al. 2007. "Polymorphisms in IL13, total IgE, eosinophilia, and asthma exacerbations in childhood." The Journal of allergy and clinical immunology 120 (1) doi:10.1016/j.jaci.2007.04.032
Lyon Helen N, Emilsson Valur, Hinney Anke, Heid Iris M, Lasky-Su Jessica, et al. 2007. "The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts." PLoS genetics 3 (4) doi:10.1371/journal.pgen.0030061
Hersh Craig P, Soto-Quirós Manuel E, Avila Lydiana, Lake Stephen L, Liang Catherine, et al. 2007. "Genome-wide linkage analysis of pulmonary function in families of children with asthma in Costa Rica." Thorax 62 (3) doi:10.1136/thx.2006.067934
Hunninghake Gary M, Soto-Quiros Manuel E, Avila Lydiana, Ly Ngoc P, Liang Catherine, et al. 2007. "Sensitization to Ascaris lumbricoides and severity of childhood asthma in Costa Rica." The Journal of allergy and clinical immunology 119 (3) doi:10.1016/j.jaci.2006.12.609
Levy Hara, Kalish Leslie A, Huntington Ian, Weller Nathaniel, Gerard Craig, et al. 2007. "Inflammatory markers of lung disease in adult patients with cystic fibrosis." Pediatric pulmonology 42 (3) doi:10.1002/ppul.20563
Raby Benjamin A, Soto-Quiros Manuel E, Avila Lydiana, Lake Stephen L, Murphy Amy, et al. 2007. "Sex-specific linkage to total serum immunoglobulin E in families of children with asthma in Costa Rica." Human molecular genetics 16 (3) doi:10.1093/hmg/ddl447
Hersh Craig P, Washko George R, Jacobson Francine L, Gill Ritu, Estepar Raul San Jose, et al. 2007. "Interobserver variability in the determination of upper lobe-predominant emphysema." Chest 131 (2) doi:10.1378/chest.06-1040
Celedón Juan C, Soto-Quiros Manuel E, Avila Lydiana, Lake Stephen L, Liang Catherine, et al. 2007. "Significant linkage to airway responsiveness on chromosome 12q24 in families of children with asthma in Costa Rica." Human genetics 120 (5) doi:10.1007/s00439-006-0255-5
Silverman Edwin K 2007. "Haplotype thinking in lung disease." Proceedings of the American Thoracic Society 4 (1) doi:10.1513/pats.200607-145JG
Hersh Craig P, DeMeo Dawn L, Reilly John J, Silverman Edwin K 2007. "Xenobiotic metabolizing enzyme gene polymorphisms predict response to lung volume reduction surgery." Respiratory research 8 doi:10.1186/1465-9921-8-59

2006

Hersh Craig P, DeMeo Dawn L, Raby Benjamin A, Litonjua Augusto A, Sylvia Jody S, et al. 2006. "Genetic linkage and association analysis of COPD-related traits on chromosome 8p." COPD 3 (4) doi:
Silverman Edwin K 2006. "Progress in chronic obstructive pulmonary disease genetics." Proceedings of the American Thoracic Society 3 (5) doi:10.1513/pats.200603-092AW
Hersh Craig P, Demeo Dawn L, Lazarus Ross, Celedón Juan C, Raby Benjamin A, et al. 2006. "Genetic association analysis of functional impairment in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 173 (9) doi:10.1164/rccm.200509-1452OC
Raby Benjamin A, Van Steen Kristel, Lazarus Ross, Celedón Juan C, Silverman Edwin K, Weiss Scott T 2006. "Eotaxin polymorphisms and serum total IgE levels in children with asthma." The Journal of allergy and clinical immunology 117 (2) doi:10.1016/j.jaci.2005.10.041
Demeo Dawn L, Mariani Thomas J, Lange Christoph, Srisuma Sorachai, Litonjua Augusto A, et al. 2006. "The SERPINE2 gene is associated with chronic obstructive pulmonary disease." American journal of human genetics 78 (2) doi:10.1086/499828
Estépar Raúl San José, Washko George G, Silverman Edwin K, Reilly John J, Kikinis Ron, Westin Carl-Fredrik 2006. "Accurate airway wall estimation using phase congruency." Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention 9 (Pt 2) doi:
Raby Benjamin A, Hwang Eun-Sook, Van Steen Kristel, Tantisira Kelan, Peng Stanford, et al. 2006. "T-bet polymorphisms are associated with asthma and airway hyperresponsiveness." American journal of respiratory and critical care medicine 173 (1) doi:10.1164/rccm.200503-505OC

2005

Kelleher Cassandra M, Silverman Edwin K, Broekelmann Thomas, Litonjua Augusto A, Hernandez Melvin, et al. 2005. "A functional mutation in the terminal exon of elastin in severe, early-onset chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 33 (4) doi:10.1165/rcmb.2005-0206OC
DeMeo Dawn L, Reilly John J, Ginns Leo C, Sylvia Jody S, Silverman Edwin K 2005. "Concordance of genotypes in pre- and post-lung transplantation DNA samples." American journal of respiratory cell and molecular biology 33 (4) doi:10.1165/rcmb.2005-0142OC
Randolph Adrienne G, Lange Christoph, Silverman Edwin K, Lazarus Ross, Weiss Scott T 2005. "Extended haplotype in the tumor necrosis factor gene cluster is associated with asthma and asthma-related phenotypes." American journal of respiratory and critical care medicine 172 (6) doi:10.1164/rccm.200501-122OC
Choudhry Shweta, Avila Pedro C, Nazario Sylvette, Ung Ngim, Kho Jennifer, et al. 2005. "CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthma." American journal of respiratory and critical care medicine 172 (2) doi:10.1164/rccm.200409-1232OC
Van Steen Kristel, McQueen Matthew B, Herbert Alan, Raby Benjamin, Lyon Helen, et al. 2005. "Genomic screening and replication using the same data set in family-based association testing." Nature genetics 37 (7) doi:10.1038/ng1582
Hersh Craig P, Demeo Dawn L, Lange Christoph, Litonjua Augusto A, Reilly John J, et al. 2005. "Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations." American journal of respiratory cell and molecular biology 33 (1) doi:10.1165/rcmb.2005-0073OC
Choudhry Shweta, Ung Ngim, Avila Pedro C, Ziv Elad, Nazario Sylvette, et al. 2005. "Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma." American journal of respiratory and critical care medicine 171 (6) doi:10.1164/rccm.200409-1286OC
Levy Hara, Raby Benjamin A, Lake Stephen, Tantisira Kelan G, Kwiatkowski David, et al. 2005. "Association of defensin beta-1 gene polymorphisms with asthma." The Journal of allergy and clinical immunology 115 (2) doi:10.1016/j.jaci.2004.11.013

2004

DeMeo Dawn L, Celedón Juan C, Lange Christoph, Reilly John J, Chapman Harold A, et al. 2004. "Genome-wide linkage of forced mid-expiratory flow in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 170 (12) doi:10.1164/rccm.200404-524OC
Raby Benjamin A, Lazarus Ross, Silverman Edwin K, Lake Steven, Lange Christoph, et al. 2004. "Association of vitamin D receptor gene polymorphisms with childhood and adult asthma." American journal of respiratory and critical care medicine 170 (10) doi:10.1164/rccm.200404-447OC
Hersh Craig P, DeMeo Dawn L, Al-Ansari Essam, Carey Vincent J, Reilly John J, et al. 2004. "Predictors of survival in severe, early onset COPD." Chest 126 (5) doi:10.1378/chest.126.5.1443
Randolph Adrienne G, Lange Christoph, Silverman Edwin K, Lazarus Ross, Silverman Eric S, et al. 2004. "The IL12B gene is associated with asthma." American journal of human genetics 75 (4) doi:10.1086/424886
Lazarus Ross, Raby Benjamin A, Lange Christoph, Silverman Edwin K, Kwiatkowski David J, et al. 2004. "TOLL-like receptor 10 genetic variation is associated with asthma in two independent samples." American journal of respiratory and critical care medicine 170 (6) doi:10.1164/rccm.200404-491OC
Celedón Juan C, Lange Christoph, Raby Benjamin A, Litonjua Augusto A, Palmer Lyle J, et al. 2004. "The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD)." Human molecular genetics 13 (15) doi:10.1093/hmg/ddh171
Tantisira Kelan G, Lake Stephen, Silverman Eric S, Palmer Lyle J, Lazarus Ross, et al. 2004. "Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids." Human molecular genetics 13 (13) doi:10.1093/hmg/ddh149
Litonjua Augusto A, Silverman Edwin K, Tantisira Kelan G, Sparrow David, Sylvia Jody S, Weiss Scott T 2004. "Beta 2-adrenergic receptor polymorphisms and haplotypes are associated with airways hyperresponsiveness among nonsmoking men." Chest 126 (1) doi:10.1378/chest.126.1.66
Raby Benjamin A, Silverman Edwin K, Kwiatkowski David J, Lange Christoph, Lazarus Ross, Weiss Scott T 2004. "ADAM33 polymorphisms and phenotype associations in childhood asthma." The Journal of allergy and clinical immunology 113 (6) doi:10.1016/j.jaci.2004.03.035
Wright Robert O, Silverman Edwin K, Schwartz Joel, Tsaih Shring-Wern, Senter Jody, et al. 2004. "Association between hemochromatosis genotype and lead exposure among elderly men: the normative aging study." Environmental health perspectives 112 (6) doi:
Burchard Esteban González, Avila Pedro C, Nazario Sylvette, Casal Jesus, Torres Alfonso, et al. 2004. "Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma." American journal of respiratory and critical care medicine 169 (3) doi:10.1164/rccm.200309-1293OC
Lyon Helen, Lange Christoph, Lake Stephen, Silverman Edwin K, Randolph Adrienne G, et al. 2004. "IL10 gene polymorphisms are associated with asthma phenotypes in children." Genetic epidemiology 26 (2) doi:10.1002/gepi.10298
Lange Christoph, van Steen Kristel, Andrew Toby, Lyon Helen, DeMeo Dawn L, et al. 2004. "A family-based association test for repeatedly measured quantitative traits adjusting for unknown environmental and/or polygenic effects." Statistical applications in genetics and molecular biology 3 doi:10.2202/1544-6115.1067
Horvath Steve, Xu Xin, Lake Stephen L, Silverman Edwin K, Weiss Scott T, Laird Nan M 2004. "Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics." Genetic epidemiology 26 (1) doi:10.1002/gepi.10295
Weiss Scott T, Lake Stephen L, Silverman Eric S, Silverman Edwin K, Richter Brent, et al. 2004. "Asthma steroid pharmacogenetics: a study strategy to identify replicated treatment responses." Proceedings of the American Thoracic Society 1 (4) doi:10.1513/pats.200409-043MS

2003

Wright Robert O, Hu Howard, Silverman Edwin K, Tsaih Shirng W, Schwartz Joel, et al. 2003. "Apolipoprotein E genotype predicts 24-month bayley scales infant development score." Pediatric research 54 (6) doi:10.1203/01.PDR.0000090927.53818.DE
Lind Denise L, Choudhry Shweta, Ung Ngim, Ziv Elad, Avila Pedro C, et al. 2003. "ADAM33 is not associated with asthma in Puerto Rican or Mexican populations." American journal of respiratory and critical care medicine 168 (11) doi:10.1164/rccm.200306-877OC
Silverman Edwin K, Kwiatkowski David J, Sylvia Jody S, Lazarus Ross, Drazen Jeffrey M, et al. 2003. "Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program." The Journal of allergy and clinical immunology 112 (5) doi:10.1016/S0091
Lange Christoph, DeMeo Dawn, Silverman Edwin K, Weiss Scott T, Laird Nan M 2003. "Using the noninformative families in family-based association tests: a powerful new testing strategy." American journal of human genetics 73 (4) doi:10.1086/378591
Raby Benjamin A, Silverman Edwin K, Lazarus Ross, Lange Christoph, Kwiatkowski David J, Weiss Scott T 2003. "Chromosome 12q harbors multiple genetic loci related to asthma and asthma-related phenotypes." Human molecular genetics 12 (16) doi:
Palmer Lyle J, Celedón Juan C, Chapman Harold A, Speizer Frank E, Weiss Scott T, Silverman Edwin K 2003. "Genome-wide linkage analysis of bronchodilator responsiveness and post-bronchodilator spirometric phenotypes in chronic obstructive pulmonary disease." Human molecular genetics 12 (10) doi:
Lange Christoph, Silverman Edwin K, Xu Xin, Weiss Scott T, Laird Nan M 2003. "A multivariate family-based association test using generalized estimating equations: FBAT-GEE." Biostatistics (Oxford, England) 4 (2) doi:10.1093/biostatistics/4.2.195
DeMeo Dawn L, Silverman Edwin K 2003. "Genetics of chronic obstructive pulmonary disease." Seminars in respiratory and critical care medicine 24 (2) doi:10.1055/s-2003-39014
Lange Christoph, Lyon Helen, DeMeo Dawn, Raby Benjamin, Silverman Edwin K, Weiss Scott T 2003. "A new powerful non-parametric two-stage approach for testing multiple phenotypes in family-based association studies." Human heredity 56 (1-3) doi:73728
Lazarus Ross, Klimecki Walter T, Raby Benjamin A, Vercelli Donata, Palmer Lyle J, et al. 2003. "Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies." Genomics 81 (1) doi:

2002

Raby Benjamin A, Klimecki Walter T, Laprise Catherine, Renaud Yannick, Faith Janet, et al. 2002. "Polymorphisms in toll-like receptor 4 are not associated with asthma or atopy-related phenotypes." American journal of respiratory and critical care medicine 166 (11) doi:10.1164/rccm.200207-634OC
Lazarus Ross, Vercelli Donata, Palmer Lyle J, Klimecki Walt J, Silverman Edwin K, et al. 2002. "Single nucleotide polymorphisms in innate immunity genes: abundant variation and potential role in complex human disease." Immunological reviews 190 doi:
Lazarus Ross, Klimecki Walter T, Palmer Lyle J, Kwiatkowski David J, Silverman Edwin K, et al. 2002. "Single-nucleotide polymorphisms in the interleukin-10 gene: differences in frequencies, linkage disequilibrium patterns, and haplotypes in three United States ethnic groups." Genomics 80 (2) doi:
Silverman Edwin K, Palmer Lyle J, Mosley Jonathan D, Barth Matthew, Senter Jody M, et al. 2002. "Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease." American journal of human genetics 70 (5) doi:10.1086/340316
Soto-Quiros Manuel E, Silverman Edwin K, Hanson Lars A, Weiss Scott T, Celedón Juan C 2002. "Maternal history, sensitization to allergens, and current wheezing, rhinitis, and eczema among children in Costa Rica." Pediatric pulmonology 33 (4) doi:
Silverman Edwin K, Mosley Jonathan D, Palmer Lyle J, Barth Matthew, Senter Jody M, et al. 2002. "Genome-wide linkage analysis of severe, early-onset chronic obstructive pulmonary disease: airflow obstruction and chronic bronchitis phenotypes." Human molecular genetics 11 (6) doi: