Rupp Jan

Top coauthors of Rupp Jan

Solbach Werner (23 papers)

Maass Matthias (17 papers)

Shima Kensuke (12 papers)

Gieffers Jens (12 papers)

Dalhoff Klaus (11 papers)

List of Rupp Jan publications


Mahnke Justus, Schumacher Valéa, Ahrens Stefanie, Käding Nadja, Feldhoff Lea Marie, et al. 2016. "Interferon Regulatory Factor 4 controls TH1 cell effector function and metabolism." Scientific reports 6 doi:10.1038/srep35521
Shima Kensuke, Coopmeiners Jonas, Graspeuntner Simon, Dalhoff Klaus, Rupp Jan 2016. "Impact of micro-environmental changes on respiratory tract infections caused by intracellular bacteria." FEBS letters doi:10.1002/1873-3468.12353
Schuchardt Larissa, Rupp Jan 2016. "Chlamydia trachomatis as the Cause of Infectious Infertility: Acute, Repetitive or Persistent Long-Term Infection?" Current topics in microbiology and immunology doi:10.1007/82_2016_15
Weckmann Markus, Schultheiss Christiane, Hollaender Anneke, Bobis Ingrid, Rupp Jan, Kopp Matthias V 2016. "Treatment with rhDNase in patients with cystic fibrosis alters in-vitro CHIT-1 activity of isolated leucocytes." Clinical and experimental immunology doi:10.1111/cei.12827
Fecher Roger A, Horwath Michael C, Friedrich Dirk, Rupp Jan, Deepe George S 2016. "Inverse Correlation between IL-10 and HIF-1α in Macrophages Infected with Histoplasma capsulatum." Journal of immunology (Baltimore, Md. : 1950) doi:10.4049/jimmunol.1600342
Pagel Julia, Hartz Annika, Figge Julia, Gille Christian, Eschweiler Simon, et al. 2016. "Regulatory T-cell frequencies are increased in preterm infants with clinical early onset sepsis." Clinical and experimental immunology doi:10.1111/cei.12810
Härtel Christoph, Hartz Annika, Bahr Lina, Gille Christian, Gortner Ludwig, et al. 2016. "Media Stories on NICU Outbreaks Lead to an Increased Prescription Rate of Third-Line Antibiotics in the Community of Neonatal Care." Infection control and hospital epidemiology doi:10.1017/ice.2016.95
Forstner Christina, Rohde Gernot, Rupp Jan, Schuette Hartwig, Ott Sebastian R, et al. 2016. "Community-acquired Haemophilus influenzae pneumonia - New insights from the CAPNETZ study." The Journal of infection 72 (5) doi:10.1016/j.jinf.2016.02.010
Suttorp Norbert, Welte Tobias, Marre Reinhard, Stenger Steffen, Pletz Mathias, et al. 2016. "[CAPNETZ : The competence network for community-acquired pneumonia (CAP)]." Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 59 (4) doi:10.1007/s00103-016-2318-7
Pletz Mathias W, Ewig Santiago, Rohde Gernot, Schuette Hartwig, Rupp Jan, et al. 2016. "Impact of pneumococcal vaccination in children on serotype distribution in adult community-acquired pneumonia using the serotype-specific multiplex urinary antigen detection assay." Vaccine doi:10.1016/j.vaccine.2016.03.052
Härtel Christoph, Hartz Annika, Pagel Julia, Rupp Jan, Stein Anja, et al. 2016. "NOD2 Loss-of-Function Mutations and Risks of Necrotizing Enterocolitis or Focal Intestinal Perforation in Very Low-birth-weight Infants." Inflammatory bowel diseases 22 (2) doi:10.1097/MIB.0000000000000658
Bollinger Thomas, Bollinger Annalena, Gies Sydney, Feldhoff Lea, Solbach Werner, Rupp Jan 2016. "Transcription regulates HIF-1α expression in CD4(+) T cells." Immunology and cell biology 94 (1) doi:10.1038/icb.2015.64
Knobloch Jürgen, Chikosi Sarah-Jane, Yanik Sarah, Rupp Jan, Jungck David, Koch Andrea 2016. "A systemic defect in Toll-like receptor 4 signaling increases lipopolysaccharide-induced suppression of IL-2-dependent T-cell proliferation in COPD." American journal of physiology. Lung cellular and molecular physiology 310 (1) doi:10.1152/ajplung.00367.2014


Kohlmann Friedrich, Shima Kensuke, Rupp Jan, Solbach Werner, Hilgenfeld Rolf, Hansen Guido 2015. "Production, crystallization and X-ray diffraction analysis of the protease CT441 from Chlamydia trachomatis." Acta crystallographica. Section F, Structural biology communications 71 (Pt 12) doi:10.1107/S2053230X15020518
Sarkar Arup, Möller Sonja, Bhattacharyya Asima, Behnen Martina, Rupp Jan, et al. 2015. "Mechanisms of apoptosis inhibition in Chlamydia pneumoniae-infected neutrophils." International journal of medical microbiology : IJMM 305 (6) doi:10.1016/j.ijmm.2015.04.006
Shima Kensuke, Klinger Matthias, Schütze Stefan, Kaufhold Inga, Solbach Werner, et al. 2015. "The role of endoplasmic reticulum-related BiP/GRP78 in interferon gamma-induced persistent Chlamydia pneumoniae infection." Cellular microbiology 17 (7) doi:10.1111/cmi.12416
Kolditz Martin, Ewig Santiago, Klapdor Benjamin, Schütte Hartwig, Winning Johannes, et al. 2015. "Community-acquired pneumonia as medical emergency: predictors of early deterioration." Thorax 70 (6) doi:10.1136/thoraxjnl-2014-206744
Dumke Roger, Schnee Christiane, Pletz Mathias W, Rupp Jan, Jacobs Enno, et al. 2015. "Mycoplasma pneumoniae and Chlamydia spp. infection in community-acquired pneumonia, Germany, 2011-2012." Emerging infectious diseases 21 (3) doi:10.3201/eid2103.140927
Wagner Christopher, Goldmann Torsten, Rohmann Kristina, Rupp Jan, Marwitz Sebastian, et al. 2015. "Budesonide Inhibits Intracellular Infection with Non-Typeable Haemophilus influenzae Despite Its Anti-Inflammatory Effects in Respiratory Cells and Human Lung Tissue: A Role for p38 MAP Kinase." Respiration; international review of thoracic diseases 90 (5) doi:10.1159/000439226
Weinmaier Thomas, Hoser Jonathan, Eck Sebastian, Kaufhold Inga, Shima Kensuke, et al. 2015. "Genomic factors related to tissue tropism in Chlamydia pneumoniae infection." BMC genomics 16 doi:10.1186/s12864-015-1377-8
Kohlmann Friedrich, Shima Kensuke, Hilgenfeld Rolf, Solbach Werner, Rupp Jan, Hansen Guido 2015. "Structural basis of the proteolytic and chaperone activity of Chlamydia trachomatis CT441." Journal of bacteriology 197 (1) doi:10.1128/JB.02140-14


Bollinger Thomas, Gies Sydney, Naujoks Julius, Feldhoff Lea, Bollinger Annalena, et al. 2014. "HIF-1α- and hypoxia-dependent immune responses in human CD4+CD25high T cells and T helper 17 cells." Journal of leukocyte biology 96 (2) doi:10.1189/jlb.3A0813-426RR
Härtel Christoph, Pagel Julia, Rupp Jan, Bendiks Meike, Guthmann Florian, et al. 2014. "Prophylactic use of Lactobacillus acidophilus/Bifidobacterium infantis probiotics and outcome in very low birth weight infants." The Journal of pediatrics 165 (2) doi:10.1016/j.jpeds.2014.04.029
Bermbach Saskia, Weinhold Karina, Roeder Thomas, Petersen Frank, Kugler Christian, et al. 2014. "Mechanisms of cilia-driven transport in the airways in the absence of mucus." American journal of respiratory cell and molecular biology 51 (1) doi:10.1165/rcmb.2012-0530OC
Käding Nadja, Szaszák Márta, Rupp Jan 2014. "Imaging of Chlamydia and host cell metabolism." Future microbiology 9 (4) doi:10.2217/fmb.14.13
Jerchel Stefan, Kaufhold Inga, Schuchardt Larissa, Shima Kensuke, Rupp Jan 2014. "Host immune responses after hypoxic reactivation of IFN-γ induced persistent Chlamydia trachomatis infection." Frontiers in cellular and infection microbiology 4 doi:10.3389/fcimb.2014.00043


Shima Kensuke, Klinger Matthias, Solbach Werner, Rupp Jan 2013. "Activities of First-Choice Antimicrobials against Gamma Interferon-Treated Chlamydia trachomatis Differ in Hypoxia." Antimicrobial agents and chemotherapy 57 (6) doi:10.1128/AAC.02211-12
Müller Constanze, Dietz Inga, Tziotis Dimitrios, Moritz Franco, Rupp Jan, Schmitt-Kopplin Philippe 2013. "Molecular cartography in acute Chlamydia pneumoniae infections-a non-targeted metabolomics approach." Analytical and bioanalytical chemistry 405 (15) doi:10.1007/s00216-013-6732-5
Szaszák Márta, Shima Kensuke, Käding Nadja, Hannus Michael, Solbach Werner, Rupp Jan 2013. "Host metabolism promotes growth of Chlamydia pneumoniae in a low oxygen environment." International journal of medical microbiology : IJMM doi:10.1016/j.ijmm.2013.03.005
Szaszák Márta, Chang Jiun Chiun, Leng Weinan, Rupp Jan, Ojcius David M, Kelley Anne Myers 2013. "Characterizing the intracellular distribution of metabolites in intact Chlamydia-infected cells by Raman and two-photon microscopy." Microbes and infection / Institut Pasteur doi:10.1016/j.micinf.2013.03.005
Rotta Detto Loria Johannes, Rohmann Kristina, Droemann Daniel, Kujath Peter, Rupp Jan, et al. 2013. "Nontypeable Haemophilus Influenzae Infection Upregulates the NLRP3 Inflammasome and Leads to Caspase-1-Dependent Secretion of Interleukin-1β - A Possible Pathway of Exacerbations in COPD." PloS one 8 (6) doi:10.1371/journal.pone.0066818
Schmidt Silvia K, Ebel Sebastian, Keil Eric, Woite Claudia, Ernst Joachim F, et al. 2013. "Regulation of IDO Activity by Oxygen Supply: Inhibitory Effects on Antimicrobial and Immunoregulatory Functions." PloS one 8 (5) doi:10.1371/journal.pone.0063301


Puzik Alexander, Rupp Jan, Tröger Birte, Göpel Wolfgang, Herting Egbert, Härtel Christoph 2012. "Insulin-like growth factor-I regulates the neonatal immune response in infection and maturation by suppression of IFN-γ." Cytokine 60 (2) doi:10.1016/j.cyto.2012.07.025
Dietz Inga, Jerchel Stefan, Szaszák Márta, Shima Kensuke, Rupp Jan 2012. "When oxygen runs short: the microenvironment drives host-pathogen interactions." Microbes and infection / Institut Pasteur 14 (4) doi:10.1016/j.micinf.2011.11.003
Nitschke Martin, Sayk Friedhelm, Härtel Christoph, Roseland Rahel Tabea, Hauswaldt Susanne, et al. 2012. "Association between azithromycin therapy and duration of bacterial shedding among patients with Shiga toxin-producing enteroaggregative Escherichia coli O104:H4." JAMA : the journal of the American Medical Association 307 (10) doi:10.1001/jama.2012.264
Jerchel Stefan, Knebel Gudrun, König Peter, Bohlmann Michael K, Rupp Jan 2012. "A human fallopian tube model for investigation of C. trachomatis infections." Journal of visualized experiments : JoVE (66) doi:10.3791/4036


Christian Jan G, Heymann Julia, Paschen Stefan A, Vier Juliane, Schauenburg Linda, et al. 2011. "Targeting of a chlamydial protease impedes intracellular bacterial growth." PLoS pathogens 7 (9) doi:10.1371/journal.ppat.1002283
Szaszák Márta, Steven Philipp, Shima Kensuke, Orzekowsky-Schröder Regina, Hüttmann Gereon, et al. 2011. "Fluorescence lifetime imaging unravels C. trachomatis metabolism and its crosstalk with the host cell." PLoS pathogens 7 (7) doi:10.1371/journal.ppat.1002108
Shima Kensuke, Szaszák Márta, Solbach Werner, Gieffers Jens, Rupp Jan 2011. "Impact of a low-oxygen environment on the efficacy of antimicrobials against intracellular Chlamydia trachomatis." Antimicrobial agents and chemotherapy 55 (5) doi:10.1128/AAC.01655-10
Knobloch Jürgen, Schild Katharina, Jungck David, Urban Katja, Müller Katja, et al. 2011. "The T-helper cell type 1 immune response to gram-negative bacterial infections is impaired in COPD." American journal of respiratory and critical care medicine 183 (2) doi:10.1164/rccm.201002-0199OC


Roth Anna, König Peter, van Zandbergen Ger, Klinger Matthias, Hellwig-Bürgel Thomas, et al. 2010. "Hypoxia abrogates antichlamydial properties of IFN-γ in human fallopian tube cells in vitro and ex vivo." Proceedings of the National Academy of Sciences of the United States of America 107 (45) doi:10.1073/pnas.1008178107
Shima Kensuke, Kuhlenbäumer Gregor, Rupp Jan 2010. "Chlamydia pneumoniae infection and Alzheimer's disease: a connection to remember?" Medical microbiology and immunology 199 (4) doi:10.1007/s00430-010-0162-1
Bunk Sebastian, Schaffert Hanne, Schmid Bianca, Goletz Christoph, Zeller Sabine, et al. 2010. "Chlamydia pneumoniae-induced memory CD4+ T-cell activation in human peripheral blood correlates with distinct antibody response patterns." Clinical and vaccine immunology : CVI 17 (5) doi:10.1128/CVI.00209-09
Borcherding Frauke, Nitschke Martin, Hundorfean Gheorghe, Rupp Jan, von Smolinski Dorthe, et al. 2010. "The CD40-CD40L pathway contributes to the proinflammatory function of intestinal epithelial cells in inflammatory bowel disease." The American journal of pathology 176 (4) doi:10.2353/ajpath.2010.090461
Drömann Daniel, Rupp Jan, Rohmann Kristina, Osbahr Sinia, Ulmer Artur J, et al. 2010. "The TGF-beta-pseudoreceptor BAMBI is strongly expressed in COPD lungs and regulated by nontypeable Haemophilus influenzae." Respiratory research 11 doi:10.1186/1465-9921-11-67
Bellmann-Weiler Rosa, Martinz Verena, Kurz Katharina, Engl Sabine, Feistritzer Clemens, et al. 2010. "Divergent modulation of Chlamydia pneumoniae infection cycle in human monocytic and endothelial cells by iron, tryptophan availability and interferon gamma." Immunobiology 215 (9-10) doi:10.1016/j.imbio.2010.05.021


Kern Jan Marco, Maass Viola, Rupp Jan, Maass Matthias 2009. "Proliferative stimulation of the vascular Endothelin-1 axis in vitro and ex vivo by infection with Chlamydia pneumoniae." Thrombosis and haemostasis 102 (4) doi:10.1160/TH09-02-0128
Härtel Christoph, Rupp Jan, Iblher Peter, Puzik Alexander, Osthues Ines, et al. 2009. "Immunomodulatory effects of Sanglifehrin A in the innate and acquired immune response of neonatal whole blood cells." Immunobiology 214 (3) doi:10.1016/j.imbio.2008.08.003
Rupp Jan, Pfleiderer Lisa, Jugert Christiane, Moeller Sonja, Klinger Matthias, et al. 2009. "Chlamydia pneumoniae hides inside apoptotic neutrophils to silently infect and propagate in macrophages." PloS one 4 (6) doi:10.1371/journal.pone.0006020


Xu Feng, Droemann Daniel, Rupp Jan, Shen Huahao, Wu Xiaohong, et al. 2008. "Modulation of the inflammatory response to Streptococcus pneumoniae in a model of acute lung tissue infection." American journal of respiratory cell and molecular biology 39 (5) doi:10.1165/rcmb.2007-0328OC
Härtel Christoph, Rupp Jan, Hoegemann Anne, Bohler Annegret, Spiegler Juliane, et al. 2008. "159C>T CD14 genotype--functional effects on innate immune responses in term neonates." Human immunology 69 (6) doi:10.1016/j.humimm.2008.04.011
Bunk Sebastian, Susnea Iuliana, Rupp Jan, Summersgill James T, Maass Matthias, et al. 2008. "Immunoproteomic identification and serological responses to novel Chlamydia pneumoniae antigens that are associated with persistent C. pneumoniae infections." Journal of immunology (Baltimore, Md. : 1950) 180 (8) doi:
Steven Philipp, Rupp Jan, Hüttmann Gereon, Koop Norbert, Lensing Carmen, et al. 2008. "Experimental induction and three-dimensional two-photon imaging of conjunctiva-associated lymphoid tissue." Investigative ophthalmology & visual science 49 (4) doi:10.1167/iovs.07-0809
Rupp Jan, Solbach Werner, Gieffers Jens 2008. "Variation in the mutation frequency determining quinolone resistance in Chlamydia trachomatis serovars L2 and D." The Journal of antimicrobial chemotherapy 61 (1) doi:10.1093/jac/dkm447


Rupp Jan, Gieffers Jens, Klinger Matthias, van Zandbergen Ger, Wrase Robert, et al. 2007. "Chlamydia pneumoniae directly interferes with HIF-1alpha stabilization in human host cells." Cellular microbiology 9 (9) doi:10.1111/j.1462-5822.2007.00948.x
Rupp Jan, Solbach Werner, Gieffers Jens 2007. "Prevalence, genetic conservation and transmissibility of the Chlamydia pneumoniae bacteriophage (phiCpn1)." FEMS microbiology letters 273 (1) doi:10.1111/j.1574-6968.2007.00785.x
Droemann Daniel, Rupp Jan, Goldmann Torsten, Uhlig Ulrike, Branscheid Detlev, et al. 2007. "Disparate innate immune responses to persistent and acute Chlamydia pneumoniae infection in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 175 (8) doi:10.1164/rccm.200607-926OC
Rattei Thomas, Ott Stephan, Gutacker Michaela, Rupp Jan, Maass Matthias, et al. 2007. "Genetic diversity of the obligate intracellular bacterium Chlamydophila pneumoniae by genome-wide analysis of single nucleotide polymorphisms: evidence for highly clonal population structure." BMC genomics 8 doi:10.1186/1471-2164-8-355


Wissel Heide, Burkhardt Wolfram, Rupp Jan, Wauer Roland R, Rüdiger Mario 2006. "Perfluorocarbons decrease Chlamydophila pneumoniae-mediated inflammatory responses of rat type II pneumocytes in vitro." Pediatric research 60 (3) doi:10.1203/01.pdr.0000233033.82664.91
Rupp Jan, Solbach Werner, Gieffers Jens 2006. "Single-nucleotide-polymorphism-specific PCR for quantification and discrimination of Chlamydia pneumoniae genotypes by use of a "locked" nucleic acid." Applied and environmental microbiology 72 (5) doi:10.1128/AEM.72.5.3785-3787.2006


von Aulock Sonja, Rupp Jan, Gueinzius Katja, Maass Matthias, Hermann Corinna 2005. "Critical investigation of the CD14 promoter polymorphism: lack of a role for in vitro cytokine response and membrane CD14 expression." Clinical and diagnostic laboratory immunology 12 (10) doi:10.1128/CDLI.12.10.1254-1256.2005
Schaaf Bernhard, Rupp Jan, Müller-Steinhardt Michael, Kruse Jan, Boehmke Florian, et al. 2005. "The interleukin-6 -174 promoter polymorphism is associated with extrapulmonary bacterial dissemination in Streptococcus pneumoniae infection." Cytokine 31 (4) doi:10.1016/j.cyto.2005.05.008
Krüll Matthias, Maass Matthias, Suttorp Norbert, Rupp Jan 2005. "Chlamydophila pneumoniae. Mechanisms of target cell infection and activation." Thrombosis and haemostasis 94 (2) doi:10.1267/THRO05020319
Siewert Katrin, Rupp Jan, Klinger Matthias, Solbach Werner, Gieffers Jens 2005. "Growth cycle-dependent pharmacodynamics of antichlamydial drugs." Antimicrobial agents and chemotherapy 49 (5) doi:10.1128/AAC.49.5.1852-1856.2005
Rupp Jan, Hellwig-Burgel Thomas, Wobbe Viola, Seitzer Ulrike, Brandt Ernst, Maass Matthias 2005. "Chlamydia pneumoniae infection promotes a proliferative phenotype in the vasculature through Egr-1 activation in vitro and in vivo." Proceedings of the National Academy of Sciences of the United States of America 102 (9) doi:10.1073/pnas.0407759102
Mitusch Rolf, Luedemann Jan, Wood William G, Berger Klaus, Schminke Ulf, et al. 2005. "Asymptomatic carotid atherosclerosis is associated with circulating chlamydia pneumoniae DNA in younger normotensive subjects in a general population survey." Arteriosclerosis, thrombosis, and vascular biology 25 (2) doi:10.1161/01.ATV.0000151284.49967.a7
Rupp Jan, Koch Marcus, van Zandbergen Ger, vanZandbergen Ger, Solbach Werner, et al. 2005. "Transmission of Chlamydia pneumoniae infection from blood monocytes to vascular cells in a novel transendothelial migration model." FEMS microbiology letters 242 (2) doi:10.1016/j.femsle.2004.11.010
Rupp Jan, Gebert Andreas, Solbach Werner, Maass Matthias 2005. "Serine-to-asparagine substitution in the GyrA gene leads to quinolone resistance in moxifloxacin-exposed Chlamydia pneumoniae." Antimicrobial agents and chemotherapy 49 (1) doi:10.1128/AAC.49.1.406-407.2005
Goldmann Torsten, Drömann Daniel, Marzouki Marouane, Schimmel Udo, Debel Karsten, et al. 2005. "Tissue microarrays from HOPE-fixed specimens allow for enhanced high throughput molecular analyses in paraffin-embedded material." Pathology, research and practice 201 (8-9) doi:10.1016/j.prp.2005.07.006


Rupp Jan, Berger Mario, Reiling Norbert, Gieffers Jens, Lindschau Carsten, et al. 2004. "Cox-2 inhibition abrogates Chlamydia pneumoniae-induced PGE2 and MMP-1 expression." Biochemical and biophysical research communications 320 (3) doi:10.1016/j.bbrc.2004.05.210
Rupp Jan, Droemann Daniel, Goldmann Torsten, Zabel Peter, Solbach Werner, et al. 2004. "Alveolar epithelial cells type II are major target cells for C. pneumoniae in chronic but not in acute respiratory infection." FEMS immunology and medical microbiology 41 (3) doi:10.1016/j.femsim.2004.03.004
Dittrich Ralf, Dragonas Charalampos, Mueller Andreas, Maltaris Theodoros, Rupp Jan, et al. 2004. "Endothelial Chlamydia pneumoniae infection promotes oxidation of LDL." Biochemical and biophysical research communications 319 (2) doi:10.1016/j.bbrc.2004.04.192
Gieffers Jens, Rupp Jan, Gebert Andreas, Solbach Werner, Klinger Matthias 2004. "First-choice antibiotics at subinhibitory concentrations induce persistence of Chlamydia pneumoniae." Antimicrobial agents and chemotherapy 48 (4) doi:
van Zandbergen Ger, Gieffers Jens, Kothe Henning, Rupp Jan, Bollinger Annalena, et al. 2004. "Chlamydia pneumoniae multiply in neutrophil granulocytes and delay their spontaneous apoptosis." Journal of immunology (Baltimore, Md. : 1950) 172 (3) doi:


Gieffers Jens, Durling Luke, Ouellette Scot P, Rupp Jan, Maass Matthias, et al. 2003. "Genotypic differences in the Chlamydia pneumoniae tyrP locus related to vascular tropism and pathogenicity." The Journal of infectious diseases 188 (8) doi:10.1086/378692
Dechend Ralf, Gieffers Jens, Dietz Rainer, Joerres Achim, Rupp Jan, et al. 2003. "Hydroxymethylglutaryl coenzyme A reductase inhibition reduces Chlamydia pneumoniae-induced cell interaction and activation." Circulation 108 (3) doi:10.1161/01.CIR.0000083367.93022.78