Barnes Peter J

Top coauthors of Barnes Peter J

Adcock Ian M (78 papers)

Ito Kazuhiro (60 papers)

Kharitonov Sergei A (41 papers)

Donnelly Louise E (28 papers)

Caramori Gaetano (23 papers)

List of Barnes Peter J publications

2016

Barnes Peter J 2016. "Glucocorticosteroids." Handbook of experimental pharmacology doi:10.1007/164_2016_62
Pelleg Amir, Schulman Edward S, Barnes Peter J 2016. "Extracellular ATP in Obstructive Airway Diseases." Chest doi:10.1016/j.chest.2016.06.045
Usmani Omar S, Singh Dave, Spinola Monica, Bizzi Andrea, Barnes Peter J 2016. "The prevalence of small airways disease in adult asthma: A systematic literature review." Respiratory medicine 116 doi:10.1016/j.rmed.2016.05.006
Barnes Peter J 2016. "Inflammatory mechanisms in patients with chronic obstructive pulmonary disease." The Journal of allergy and clinical immunology 138 (1) doi:10.1016/j.jaci.2016.05.011
Barnes Peter J 2016. "Kinases as Novel Therapeutic Targets in Asthma and Chronic Obstructive Pulmonary Disease." Pharmacological reviews 68 (3) doi:10.1124/pr.116.012518
Verbanck Sylvia, Ghorbaniasl Ghader, Biddiscombe Martyn F, Dragojlovic Dusica, Ricks Nathan, et al. 2016. "Inhaled Aerosol Distribution in Human Airways: A Scintigraphy-Guided Study in a 3D Printed Model." Journal of aerosol medicine and pulmonary drug delivery doi:10.1089/jamp.2016.1291
Cosío Borja G, Shafiek Hanna, Iglesias Amanda, Yanez Aina, Cordova Rocio, et al. 2016. "Oral Low-Dose Theophylline on Top of Inhaled Fluticasone-Salmeterol Does Not Reduce Exacerbations in Patients with Severe COPD: A Pilot Clinical Trial." Chest doi:10.1016/j.chest.2016.04.011
Costa Claudia, Traves Suzanne L, Tudhope Susan J, Fenwick Peter S, Belchamber Kylie B R, et al. 2016. "Enhanced monocyte migration to CXCR3 and CCR5 chemokines in COPD." The European respiratory journal doi:10.1183/13993003.01642-2015
Lee Jin, Machin Matthew, Russell Kirsty E, Pavlidis Stelios, Zhu Jie, et al. 2016. "Corticosteroid modulation of immunoglobulin expression and B-cell function in COPD." FASEB journal : official publication of the Federation of American Societies for Experimental Biology doi:10.1096/fj.201500135
Mitani Akihisa, Ito Kazuhiro, Vuppusetty Chaitanya, Barnes Peter J, Mercado Nicolas 2016. "Restoration of Corticosteroid Sensitivity in Chronic Obstructive Pulmonary Disease by Inhibition of Mammalian Target of Rapamycin." American journal of respiratory and critical care medicine 193 (2) doi:10.1164/rccm.201503-0593OC
Kobayashi Yoshiki, Ito Kazuhiro, Kanda Akira, Tomoda Koich, Miller-Larsson Anna, et al. 2016. "Protein tyrosine phosphatase PTP-RR regulates corticosteroid sensitivity." Respiratory research 17 (1) doi:10.1186/s12931-016-0349-0
Russell Kirsty E, Chung Kian Fan, Clarke Colin J, Durham Andrew L, Mallia Patrick, et al. 2016. "The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD." PloS one 11 (1) doi:10.1371/journal.pone.0146102
Footitt Joseph, Mallia Patrick, Durham Andrew L, Ho W Eugene, Trujillo-Torralbo Maria-Belen, et al. 2016. "Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD." Chest 149 (1) doi:10.1378/chest.14-2637
Maneechotesuwan Kittipong, Kasetsinsombat Kanda, Wongkajornsilp Adisak, Barnes Peter J 2016. "Simvastatin up-regulates adenosine deaminase and suppresses osteopontin expression in COPD patients through an IL-13-dependent mechanism." Respiratory research 17 (1) doi:10.1186/s12931-016-0424-6
Poletti Donatella, Iannini Valeria, Casolari Paolo, Contoli Marco, Papi Alberto, et al. 2016. "Nasal inflammation and its response to local glucocorticoid regular treatment in patients with persistent non-allergic rhinitis: a pilot study." Journal of inflammation (London, England) 13 doi:10.1186/s12950-016-0134-3
Bewley Martin A, Belchamber Kylie B R, Chana Kirandeep K, Budd Richard C, Donaldson Gavin, et al. 2016. "Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD." PloS one 11 (9) doi:10.1371/journal.pone.0163139

2015

Leaker Brian R, Scadding Glenis, Jones C Richard, Barnes Peter J 2015. "Using magnetic resonance imaging to quantify the inflammatory response following allergen challenge in allergic rhinitis." Immunity, inflammation and disease 3 (4) doi:10.1002/iid3.86
Gao Wei, Yuan Cheng, Zhang Jingying, Li Lingling, Yu Like, et al. 2015. "Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury." Clinical science (London, England : 1979) 129 (12) doi:10.1042/CS20150273
van de Kant Kim D G, Paredi Paolo, Meah Sally, Kalsi Harpal S, Barnes Peter J, Usmani Omar S 2015. "The effect of body weight on distal airway function and airway inflammation." Obesity research & clinical practice doi:10.1016/j.orcp.2015.10.005
Ngkelo Anta, Hoffmann Roland F, Durham Andrew L, Marwick John A, Brandenburg Simone M, et al. 2015. "Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD." American journal of physiology. Lung cellular and molecular physiology 309 (10) doi:10.1152/ajplung.00077.2015
Maneechotesuwan Kittipong, Wongkajornsilp Adisak, Adcock Ian M, Barnes Peter J 2015. "Simvastatin Suppresses Airway IL-17 and Upregulates IL-10 in Patients With Stable COPD." Chest 148 (5) doi:10.1378/chest.14-3138
Gastaldi Ada Clarice, Paredi Paolo, Talwar Anjana, Meah Sally, Barnes Peter J, Usmani Omar S 2015. "Oscillating Positive Expiratory Pressure on Respiratory Resistance in Chronic Obstructive Pulmonary Disease With a Small Amount of Secretion: A Randomized Clinical Trial." Medicine 94 (42) doi:10.1097/MD.0000000000001845
Bikov Andras, Pride Neil B, Goldman Michael D, Hull James H, Horvath Ildiko, et al. 2015. "Glottal Aperture and Buccal Airflow Leaks Critically Affect Forced Oscillometry Measurements." Chest 148 (3) doi:10.1378/chest.14-2644
Barnes Peter J 2015. "Therapeutic approaches to asthma-chronic obstructive pulmonary disease overlap syndromes." The Journal of allergy and clinical immunology 136 (3) doi:10.1016/j.jaci.2015.05.052
Wiegman Coen H, Michaeloudes Charalambos, Haji Gulammehdi, Narang Priyanka, Clarke Colin J, et al. 2015. "Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease." The Journal of allergy and clinical immunology 136 (3) doi:10.1016/j.jaci.2015.01.046
Basoglu Ozen K, Barnes Peter J, Kharitonov Sergei A, Pelleg Amir 2015. "Effects of Aerosolized Adenosine 5'-Triphosphate in Smokers and Patients With COPD." Chest 148 (2) doi:10.1378/chest.14-2285
Barnes Peter J 2015. "Identifying Molecular Targets for New Drug Development for Chronic Obstructive Pulmonary Disease: What Does the Future Hold?" Seminars in respiratory and critical care medicine 36 (4) doi:10.1055/s-0035-1555611
Gao Wei, Li Lingling, Wang Yujie, Zhang Sini, Adcock Ian M, et al. 2015. "Bronchial epithelial cells: The key effector cells in the pathogenesis of chronic obstructive pulmonary disease?" Respirology (Carlton, Vic.) 20 (5) doi:10.1111/resp.12542
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar A, et al. 2015. "An official American Thoracic Society/European Respiratory Society statement: research questions in COPD." European respiratory review : an official journal of the European Respiratory Society 24 (136) doi:10.1183/16000617.00000315
Haghgoo Seyyed Mortaza, Allameh Abdolamir, Mortaz Esmaeil, Garssen Johan, Folkerts Gert, et al. 2015. "Pharmacogenomics and targeted therapy of cancer: Focusing on non-small cell lung cancer." European journal of pharmacology 754 doi:10.1016/j.ejphar.2015.02.029
Mercado Nicolas, Ito Kazuhiro, Barnes Peter J 2015. "Accelerated ageing of the lung in COPD: new concepts." Thorax 70 (5) doi:10.1136/thoraxjnl-2014-206084
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar, et al. 2015. "An official American Thoracic Society/European Respiratory Society statement: research questions in COPD." The European respiratory journal 45 (4) doi:10.1183/09031936.00009015
Celli Bartolome R, Decramer Marc, Wedzicha Jadwiga A, Wilson Kevin C, Agustí Alvar, et al. 2015. "An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 191 (7) doi:10.1164/rccm.201501-0044ST
Leaker Brian R, Barnes Peter J, Jones C Richard, Tutuncu Ahmet, Singh Dave 2015. "Efficacy and safety of nebulized glycopyrrolate for administration using a high efficiency nebulizer in patients with chronic obstructive pulmonary disease." British journal of clinical pharmacology 79 (3) doi:10.1111/bcp.12517
Barnes Peter J 2015. "Mechanisms of development of multimorbidity in the elderly." The European respiratory journal 45 (3) doi:10.1183/09031936.00229714
Bi Hui, Zhou Ji, Wu Dandan, Gao Wei, Li Lingling, et al. 2015. "Microarray analysis of long non-coding RNAs in COPD lung tissue." Inflammation research : official journal of the European Histamine Research Society ... [et al.] 64 (2) doi:10.1007/s00011-014-0790-9
Mortaz Esmaeil, Adcock Ian M, Tabarsi Payam, Masjedi Mohammad Reza, Mansouri Davood, et al. 2015. "Interaction of Pattern Recognition Receptors with Mycobacterium Tuberculosis." Journal of clinical immunology 35 (1) doi:10.1007/s10875-014-0103-7
Higaki Manabu, Wada Hiroo, Mikura Shinichiro, Yasutake Tetsuo, Nakamura Masuo, et al. 2015. "Interleukin-10 modulates pulmonary neutrophilic inflammation induced by cigarette smoke exposure." Experimental lung research 41 (10) doi:10.3109/01902148.2015.1096315
Fenwick Peter S, Macedo Patricia, Kilty Iain C, Barnes Peter J, Donnelly Louise E 2015. "Effect of JAK Inhibitors on Release of CXCL9, CXCL10 and CXCL11 from Human Airway Epithelial Cells." PloS one 10 (6) doi:10.1371/journal.pone.0128757
Barnes Peter J, Burney Peter G J, Silverman Edwin K, Celli Bartolome R, Vestbo Jørgen, et al. 2015. "Chronic obstructive pulmonary disease." Nature reviews. Disease primers 1 doi:10.1038/nrdp.2015.76

2014

Mortaz Esmaeil, Adcock Ian M, Barnes Peter J 2014. "Sarcoidosis: Role of non-tuberculosis mycobacteria and Mycobacterium tuberculosis." International journal of mycobacteriology 3 (4) doi:10.1016/j.ijmyco.2014.10.008
Wu Dandan, Zhou Ji, Bi Hui, Li Lingling, Gao Wei, et al. 2014. "CCL11 as a potential diagnostic marker for asthma?" The Journal of asthma : official journal of the Association for the Care of Asthma 51 (8) doi:10.3109/02770903.2014.917659
Di Stefano Antonino, Caramori Gaetano, Barczyk Adam, Vicari Chiara, Brun Paola, et al. 2014. "Innate immunity but not NLRP3 inflammasome activation correlates with severity of stable COPD." Thorax 69 (6) doi:10.1136/thoraxjnl-2012-203062
Michaeloudes Charalambos, Mercado Nicolas, Clarke Colin, Bhavsar Pankaj K, Adcock Ian M, et al. 2014. "Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression." Journal of immunology (Baltimore, Md. : 1950) 192 (10) doi:10.4049/jimmunol.1301984
Dhariwal Jaideep, Tennant Rachel C, Hansell David M, Westwick John, Walker Christoph, et al. 2014. "Smoking cessation in COPD causes a transient improvement in spirometry and decreases micronodules on high-resolution CT imaging." Chest 145 (5) doi:10.1378/chest.13-2220
Barnes Peter J 2014. "Cellular and molecular mechanisms of chronic obstructive pulmonary disease." Clinics in chest medicine 35 (1) doi:10.1016/j.ccm.2013.10.004
Wiegman Coen H, Li Feng, Clarke Colin J, Jazrawi Elen, Kirkham Paul, et al. 2014. "A comprehensive analysis of oxidative stress in the ozone-induced lung inflammation mouse model." Clinical science (London, England : 1979) 126 (6) doi:10.1042/CS20130039
Kirkham Paul A, Whiteman Matthew, Winyard Paul G, Caramori Gaetano, Gordon Fabiana, et al. 2014. "Impact of theophylline/corticosteroid combination therapy on sputum hydrogen sulfide levels in patients with COPD." The European respiratory journal doi:10.1183/09031936.00131513
Kobayashi Yoshiki, Bossley Cara, Gupta Atul, Akashi Kenichi, Tsartsali Lemonia, et al. 2014. "Passive smoking impairs histone deacetylase-2 in children with severe asthma." Chest 145 (2) doi:10.1378/chest.13-0835
Barnes Peter J 2014. "Glucocorticoids." Chemical immunology and allergy 100 doi:10.1159/000359984
Hashemian Seyed Mohamad Reza, Mortaz Esmaeil, Tabarsi Payam, Jamaati Hamidreza, Maghsoomi Zohreh, et al. 2014. "Elevated CXCL-8 expression in bronchoalveolar lavage correlates with disease severity in patients with acute respiratory distress syndrome resulting from tuberculosis." Journal of inflammation (London, England) 11 doi:10.1186/1476-9255-11-21
Barczyk Adam, Pierzchala Wladyslaw, Caramori Gaetano, Wiaderkiewicz Ryszard, Kaminski Marcin, et al. 2014. "Decreased percentage of CD4(+)Foxp3(+)TGF-β(+) and increased percentage of CD4(+)IL-17(+) cells in bronchoalveolar lavage of asthmatics." Journal of inflammation (London, England) 11 doi:10.1186/1476-9255-11-22
Khan Younis M, Kirkham Paul, Barnes Peter J, Adcock Ian M 2014. "Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells." PloS one 9 (4) doi:10.1371/journal.pone.0095051
Liang Zhike, Zhang Qingling, Thomas Catherine Mr, Chana Kirandeep K, Gibeon David, et al. 2014. "Impaired macrophage phagocytosis of bacteria in severe asthma." Respiratory research 15 doi:10.1186/1465-9921-15-72
Chana Kirandeep K, Fenwick Peter S, Nicholson Andrew G, Barnes Peter J, Donnelly Louise E 2014. "Identification of a distinct glucocorticosteroid-insensitive pulmonary macrophage phenotype in patients with chronic obstructive pulmonary disease." The Journal of allergy and clinical immunology 133 (1) doi:10.1016/j.jaci.2013.08.044
Singh Richa, Mackay Alexander J, Patel Anant Rc, Garcha Davinder S, Kowlessar Beverly S, et al. 2014. "Inflammatory thresholds and the species-specific effects of colonising bacteria in stable chronic obstructive pulmonary disease." Respiratory research 15 doi:10.1186/s12931-014-0114-1
Mercado Nicolas, Kizawa Yasuo, Ueda Keitaro, Xiong Yeping, Kimura Genki, et al. 2014. "Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers." PloS one 9 (2) doi:10.1371/journal.pone.0088168
Paredi Paolo, Kharitonov Sergei A, Meah Sally, Barnes Peter J, Usmani Omar S 2014. "A novel approach to partition central and peripheral airway nitric oxide." Chest 145 (1) doi:10.1378/chest.13-0843
Zhu Alling, Ge Dehai, Zhang Jingying, Teng Yue, Yuan Cheng, et al. 2014. "Sputum myeloperoxidase in chronic obstructive pulmonary disease." European journal of medical research 19 doi:10.1186/2047-783X-19-12
Kankaanranta Hannu, Ilmarinen Pinja, Zhang Xianzhi, Adcock Ian M, Lahti Aleksi, et al. 2014. "Tumour necrosis factor-α regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-κB and AP-1." PloS one 9 (2) doi:10.1371/journal.pone.0090298
Leaker Brian R, Singh Dave, Ali Ferhana Y, Barnes Peter J, O'Connor Brian 2014. "The effect of the novel phosphodiesterase-4 inhibitor MEM 1414 on the allergen induced responses in mild asthma." BMC pulmonary medicine 14 doi:10.1186/1471-2466-14-166

2013

Paschalaki Koralia E, Starke Richard D, Hu Yanhua, Mercado Nicolas, Margariti Andriana, et al. 2013. "Dysfunction of endothelial progenitor cells from smokers and chronic obstructive pulmonary disease patients due to increased DNA damage and senescence." Stem cells (Dayton, Ohio) 31 (12) doi:10.1002/stem.1488
Hakim Amir, Barnes Peter J, Adcock Ian M, Usmani Omar S 2013. "Importin-7 mediates glucocorticoid receptor nuclear import and is impaired by oxidative stress, leading to glucocorticoid insensitivity." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27 (11) doi:10.1096/fj.12-222604
Haque Rubaiyat, Hakim Amir, Moodley Thunicia, Torrego Alfonso, Essilfie-Quaye Sarah, et al. 2013. "Inhaled long-acting β2 agonists enhance glucocorticoid receptor nuclear translocation and efficacy in sputum macrophages in COPD." The Journal of allergy and clinical immunology 132 (5) doi:10.1016/j.jaci.2013.07.038
Papi Alberto, Contoli Marco, Adcock Ian M, Bellettato Cinzia, Padovani Anna, et al. 2013. "Rhinovirus infection causes steroid resistance in airway epithelium through nuclear factor κB and c-Jun N-terminal kinase activation." The Journal of allergy and clinical immunology doi:10.1016/j.jaci.2013.05.028
Bikov Andras, Paschalaki Koralia, Logan-Sinclair Ron, Horváth Ildiko, Kharitonov Sergei A, et al. 2013. "Standardised exhaled breath collection for the measurement of exhaled volatile organic compounds by proton transfer reaction mass spectrometry." BMC pulmonary medicine 13 (1) doi:10.1186/1471-2466-13-43
Barnes Peter J 2013. "New anti-inflammatory targets for chronic obstructive pulmonary disease." Nature reviews. Drug discovery 12 (7) doi:
Kirkham Paul A, Barnes Peter J 2013. "Oxidative stress in COPD." Chest 144 (1) doi:10.1378/chest.12-2664
Durham Andrew L, McLaren Alistair, Hayes Brian P, Caramori Gaetano, Clayton Chris L, et al. 2013. "Regulation of Wnt4 in chronic obstructive pulmonary disease." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27 (6) doi:10.1096/fj.12-217083
Barnes Peter J 2013. "Theophylline." American journal of respiratory and critical care medicine doi:10.1164/rccm.201302-0388PP
Binia Aristea, Van Stiphout Nicole, Liang Liming, Michel Sven, Bhavsar Pankaj K, et al. 2013. "A Polymorphism Affecting MYB Binding within the Promoter of the PDCD4 Gene is Associated with Severe Asthma in Children." Human mutation doi:10.1002/humu.22340
To Masako, Takagi Dai, Akashi Kenichi, Kano Ichino, Haruki Kosuke, et al. 2013. "Sputum PAI-1 elevation by oxidative stress-dependent NF-κB activation in chronic obstructive pulmonary disease." Chest doi:10.1378/chest.12-2381
Maneechotesuwan Kittipong, Kasetsinsombat Kanda, Wongkajornsilp Adisak, Barnes Peter J 2013. "Decreased indoleamine 2,3-dioxygenase activity and IL-10/IL-17A ratio in patients with COPD." Thorax 68 (4) doi:10.1136/thoraxjnl-2012-202127
Kobayashi Yoshiki, Wada Hiroo, Rossios Christos, Takagi Dai, Higaki Manabu, et al. 2013. "A novel macrolide solithromycin exerts superior anti-inflammatory effect via NF-κB inhibition." The Journal of pharmacology and experimental therapeutics 345 (1) doi:10.1124/jpet.112.200733
Barnes Peter J 2013. "Development of New Drugs for COPD." Current medicinal chemistry 20 (12) doi:
Barnes Peter J 2013. "Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease." The Journal of allergy and clinical immunology 131 (3) doi:10.1016/j.jaci.2012.12.1564
Brown Stephanie M, Koarai Akira, Sturton Richard G, Nicholson Andrew G, Barnes Peter J, Donnelly Louise E 2013. "A role for M2 and M3 muscarinic receptors in the contraction of rat and human small airways." European journal of pharmacology 702 (1-3) doi:10.1016/j.ejphar.2013.01.054
Vestbo Jørgen, Hurd Suzanne S, Agustí Alvar G, Jones Paul W, Vogelmeier Claus, et al. 2013. "Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary." American journal of respiratory and critical care medicine 187 (4) doi:10.1164/rccm.201204-0596PP
Kimura Genki, Ueda Keitaro, Eto Shouichi, Watanabe Yuji, Masuko Takashi, et al. 2013. "Toll-like receptor 3 stimulation causes corticosteroid-refractory airway neutrophilia and hyperresponsiveness in mice." Chest doi:10.1378/chest.12-2610
Leaker Brian R, Barnes Peter J, O'Connor Brian 2013. "Inhibition of LPS-induced airway neutrophilic inflammation in healthy volunteers with an oral CXCR2 antagonist." Respiratory research 14 doi:10.1186/1465-9921-14-137
Mortaz Esmaeil, Adcock Ian M, Folkerts Gert, Barnes Peter J, Paul Vos Arjan, Garssen Johan 2013. "Probiotics in the management of lung diseases." Mediators of inflammation 2013 doi:10.1155/2013/751068
Montuschi Paolo, Mores Nadia, Trové Andrea, Mondino Chiara, Barnes Peter J 2013. "The electronic nose in respiratory medicine." Respiration; international review of thoracic diseases 85 (1) doi:10.1159/000340044

2012

Gelb Arthur F, Barnes Peter J, George Steven C, Ricciardolo Fabio L M, DiMaria Giussepe, Zamel Noe 2012. "Review of exhaled nitric oxide in chronic obstructive pulmonary disease." Journal of breath research 6 (4) doi:10.1088/1752-7155/6/4/047101
Mallia Patrick, Footitt Joseph, Sotero Rosa, Jepson Annette, Contoli Marco, et al. 2012. "Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 186 (11) doi:10.1164/rccm.201205-0806OC
Barnes Peter J 2012. "New drugs for asthma." Seminars in respiratory and critical care medicine 33 (6) doi:10.1055/s-0032-1326965
Louis Renaud, Schleich Florence, Barnes Peter J 2012. "Corticosteroids: still at the frontline in asthma treatment?" Clinics in chest medicine 33 (3) doi:10.1016/j.ccm.2012.05.004
Kobayashi Yoshiki, Mercado Nicolas, Miller-Larsson Anna, Barnes Peter J, Ito Kazuhiro 2012. "Increased corticosteroid sensitivity by a long acting β2 agonist formoterol via β2 adrenoceptor independent protein phosphatase 2A activation." Pulmonary pharmacology & therapeutics 25 (3) doi:10.1016/j.pupt.2012.02.005
To Masako, Yamamura Satoshi, Akashi Kenichi, Charron Catherine E, Barnes Peter J, Ito Kazuhiro 2012. "Defect of adaptation to hypoxia in patients with COPD due to reduction of histone deacetylase 7." Chest 141 (5) doi:10.1378/chest.11-1536
Donnelly Louise E, Barnes Peter J 2012. "Defective phagocytosis in airways disease." Chest 141 (4) doi:10.1378/chest.11-2348
Antczak Adam, Ciebiada Maciej, Kharitonov Sergei A, Gorski Pawel, Barnes Peter J 2012. "Inflammatory markers: exhaled nitric oxide and carbon monoxide during the ovarian cycle." Inflammation 35 (2) doi:10.1007/s10753-011-9345-1
Montuschi Paolo, Paris Debora, Melck Dominique, Lucidi Vincenzina, Ciabattoni Giovanni, et al. 2012. "NMR spectroscopy metabolomic profiling of exhaled breath condensate in patients with stable and unstable cystic fibrosis." Thorax 67 (3) doi:10.1136/thoraxjnl-2011-200072
Usmani Omar S, Barnes Peter J 2012. "Assessing and treating small airways disease in asthma and chronic obstructive pulmonary disease." Annals of medicine 44 (2) doi:10.3109/07853890.2011.585656
Yao Xin, Zha Wangjian, Song Wei, He Haiyan, Huang Mao, et al. 2012. "Coordinated regulation of IL-4 and IL-13 expression in human T cells: 3C analysis for DNA looping." Biochemical and biophysical research communications 417 (3) doi:10.1016/j.bbrc.2011.12.069
Osoata Grace O, Ito Misako, Elliot Mark, Hogg James, Barnes Peter J, Ito Kazuhiro 2012. "Reduced denitration activity in peripheral lung of chronic obstructive pulmonary disease." Tanaffos 11 (4) doi:
Barnes Peter J, Nicolini Gabriele, Bizzi Andrea, Spinola Monica, Singh Dave 2012. "Do inhaled corticosteroid/long-acting beta2-agonist fixed combinations provide superior clinical benefits compared with separate inhalers? A literature reappraisal." Allergy and asthma proceedings : the official journal of regional and state allergy societies 33 (2) doi:10.2500/aap.2012.33.3512
Barnes Peter J 2012. "Severe asthma: advances in current management and future therapy." The Journal of allergy and clinical immunology 129 (1) doi:10.1016/j.jaci.2011.11.006
Yuan Cheng, Zhou Lin, Cheng Jiyun, Zhang Jingying, Teng Yue, et al. 2012. "Statins as potential therapeutic drug for asthma?" Respiratory research 13 doi:10.1186/1465-9921-13-108
Tomita Katsuyuki, Caramori Gaetano, Ito Kazuhiro, Sano Hiroyuki, Lim Sam, et al. 2012. "STAT6 expression in T cells, alveolar macrophages and bronchial biopsies of normal and asthmatic subjects." Journal of inflammation (London, England) 9 doi:10.1186/1476-9255-9-5
Mercado Nicolas, Hakim Amir, Kobayashi Yoshiki, Meah Sally, Usmani Omar S, et al. 2012. "Restoration of corticosteroid sensitivity by p38 mitogen activated protein kinase inhibition in peripheral blood mononuclear cells from severe asthma." PloS one 7 (7) doi:10.1371/journal.pone.0041582

2011

Essilfie-Quaye Sarah, Ito Kazuhiro, Ito Misako, Kharitonov Sergei A, Barnes Peter J 2011. "Comparison of Symbicort® versus Pulmicort® on steroid pharmacodynamic markers in asthma patients." Respiratory medicine 105 (12) doi:10.1016/j.rmed.2011.08.020
Montuschi Paolo, Barnes Peter J 2011. "New perspectives in pharmacological treatment of mild persistent asthma." Drug discovery today 16 (23-24) doi:10.1016/j.drudis.2011.09.005
Mercado Nicholas, To Yasuo, Kobayashi Yoshiki, Adcock Ian M, Barnes Peter J, Ito Kazuhiro 2011. "p38 mitogen-activated protein kinase-γ inhibition by long-acting β2 adrenergic agonists reversed steroid insensitivity in severe asthma." Molecular pharmacology 80 (6) doi:10.1124/mol.111.071993
Gajdocsi Reka, Bikov Andras, Antus Balazs, Horvath Ildiko, Barnes Peter J, Kharitonov Sergei A 2011. "Assessment of reproducibility of exhaled hydrogen peroxide concentration and the effect of breathing pattern in healthy subjects." Journal of aerosol medicine and pulmonary drug delivery 24 (6) doi:10.1089/jamp.2011.0875
Rossios Christos, To Yasuo, To Masako, Ito Misako, Barnes Peter J, et al. 2011. "Long-acting fluticasone furoate has a superior pharmacological profile to fluticasone propionate in human respiratory cells." European journal of pharmacology 670 (1) doi:10.1016/j.ejphar.2011.08.022
Barnes Peter J 2011. "Interview with Peter Barnes." Future medicinal chemistry 3 (13) doi:10.4155/fmc.11.100
Kirkham Paul A, Caramori Gaetano, Casolari Paolo, Papi Alberto A, Edwards Matt, et al. 2011. "Oxidative stress-induced antibodies to carbonyl-modified protein correlate with severity of chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 184 (7) doi:10.1164/rccm.201010-1605OC
Nicholson Grant C, Kariyawasam Harsha H, Tan Andrew J, Hohlfeld Jens M, Quinn Deborah, et al. 2011. "The effects of an anti-IL-13 mAb on cytokine levels and nasal symptoms following nasal allergen challenge." The Journal of allergy and clinical immunology 128 (4) doi:10.1016/j.jaci.2011.05.013
Barnes Peter J 2011. "Biochemical basis of asthma therapy." The Journal of biological chemistry 286 (38) doi:10.1074/jbc.R110.206466
To Masako, Ito Kazuhiro, Ausin Pilar M, Kharitonov Sergei A, Barnes Peter J 2011. "Osteoprotegerin in sputum is a potential biomarker in COPD." Chest 140 (1) doi:10.1378/chest.10-1608
Barnes Peter J 2011. "Pathophysiology of allergic inflammation." Immunological reviews 242 (1) doi:10.1111/j.1600-065X.2011.01020.x
Teng Yue, Sun Peili, Zhang Jingying, Yu Rongbin, Bai Jianling, et al. 2011. "Hydrogen peroxide in exhaled breath condensate in patients with asthma: a promising biomarker?" Chest 140 (1) doi:10.1378/chest.10-2816
Pridgeon Carol, Bugeon Laurence, Donnelly Louise, Straschil Ursula, Tudhope Susan J, et al. 2011. "Regulation of IL-17 in chronic inflammation in the human lung." Clinical science (London, England : 1979) 120 (12) doi:10.1042/CS20100417
Caramori Gaetano, Adcock Ian M, Casolari Paolo, Ito Kazuhiro, Jazrawi Elen, et al. 2011. "Unbalanced oxidant-induced DNA damage and repair in COPD: a link towards lung cancer." Thorax 66 (6) doi:10.1136/thx.2010.156448
Barnes Peter J 2011. "Glucocorticosteroids: current and future directions." British journal of pharmacology 163 (1) doi:10.1111/j.1476-5381.2010.01199.x
Mercado Nicolas, To Yasuo, Ito Kazuhiro, Barnes Peter J 2011. "Nortriptyline reverses corticosteroid insensitivity by inhibition of phosphoinositide-3-kinase-δ." The Journal of pharmacology and experimental therapeutics 337 (2) doi:10.1124/jpet.110.175950
Mercado Nicolas, Thimmulappa Rajesh, Thomas Catherine M R, Fenwick Peter S, Chana Kirandeep K, et al. 2011. "Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress." Biochemical and biophysical research communications 406 (2) doi:10.1016/j.bbrc.2011.02.035
Mortaz Esmaeil, Masjedi Mohammad Reza, Barnes Peter J, Adcock Ian M 2011. "Epigenetics and chromatin remodeling play a role in lung disease." Tanaffos 10 (4) doi:
Antczak Adam, Piotrowski Wojciech, Marczak Jerzy, Ciebiada Maciej, Gorski Pawel, Barnes Peter J 2011. "Correlation between eicosanoids in bronchoalveolar lavage fluid and in exhaled breath condensate." Disease markers 30 (5) doi:10.3233/DMA-2011-0776
O'Connor Brian J, Collarini Sara, Poli Gianluigi, Brindicci Caterina, Spinola Monica, et al. 2011. "Rapid effects of extrafine beclomethasone dipropionate/formoterol fixed combination inhaler on airway inflammation and bronchoconstriction in asthma: a randomised controlled trial." BMC pulmonary medicine 11 doi:10.1186/1471-2466-11-60
Kobayashi Yoshiki, Mercado Nicolas, Barnes Peter J, Ito Kazuhiro 2011. "Defects of protein phosphatase 2A causes corticosteroid insensitivity in severe asthma." PloS one 6 (12) doi:10.1371/journal.pone.0027627
Caramori Gaetano, Lasagna Lisa, Casalini Angelo G, Adcock Ian M, Casolari Paolo, et al. 2011. "Immune response to Mycobacterium tuberculosis infection in the parietal pleura of patients with tuberculous pleurisy." PloS one 6 (7) doi:10.1371/journal.pone.0022637
Adcock Ian M, Caramori Gaetano, Barnes Peter J 2011. "Chronic obstructive pulmonary disease and lung cancer: new molecular insights." Respiration; international review of thoracic diseases 81 (4) doi:10.1159/000324601

2010

Maneechotesuwan Kittipong, Ekjiratrakul Wuttichai, Kasetsinsombat Kanda, Wongkajornsilp Adisak, Barnes Peter J 2010. "Statins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase." The Journal of allergy and clinical immunology 126 (4) doi:10.1016/j.jaci.2010.08.005
To Yasuo, Ito Kazuhiro, Kizawa Yasuo, Failla Marco, Ito Misako, et al. 2010. "Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 182 (7) doi:10.1164/rccm.200906-0937OC
Barnes Peter J, Dweik Raed A, Gelb Arthur F, Gibson Peter G, George Steven C, et al. 2010. "Exhaled nitric oxide in pulmonary diseases: a comprehensive review." Chest 138 (3) doi:10.1378/chest.09-2090
Finney-Hayward Tricia K, Popa Mariana Oana, Bahra Parmjit, Li Su, Poll Christopher T, et al. 2010. "Expression of transient receptor potential C6 channels in human lung macrophages." American journal of respiratory cell and molecular biology 43 (3) doi:10.1165/rcmb.2008-0373OC
Cooper Philip R, Poll Christopher T, Barnes Peter J, Sturton R Graham 2010. "Involvement of IL-13 in tobacco smoke-induced changes in the structure and function of rat intrapulmonary airways." American journal of respiratory cell and molecular biology 43 (2) doi:10.1165/rcmb.2009-0117OC
Barnes Peter J 2010. "New therapies for asthma: is there any progress?" Trends in pharmacological sciences 31 (7) doi:10.1016/j.tips.2010.04.009
Barnes Peter J, Pocock Stuart J, Magnussen Helgo, Iqbal Amir, Kramer Benjamin, et al. 2010. "Integrating indacaterol dose selection in a clinical study in COPD using an adaptive seamless design." Pulmonary pharmacology & therapeutics 23 (3) doi:10.1016/j.pupt.2010.01.003
Ford Paul A, Durham Andrew L, Russell Richard E K, Gordon Fabiana, Adcock Ian M, Barnes Peter J 2010. "Treatment effects of low-dose theophylline combined with an inhaled corticosteroid in COPD." Chest 137 (6) doi:10.1378/chest.09-2363
Barnes Peter J 2010. "Mechanisms and resistance in glucocorticoid control of inflammation." The Journal of steroid biochemistry and molecular biology 120 (2-3) doi:10.1016/j.jsbmb.2010.02.018
Montuschi Paolo, Santonico Marco, Mondino Chiara, Pennazza Giorgio, Mantini Giulia, et al. 2010. "Diagnostic performance of an electronic nose, fractional exhaled nitric oxide, and lung function testing in asthma." Chest 137 (4) doi:10.1378/chest.09-1836
Varani Katia, Caramori Gaetano, Vincenzi Fabrizio, Tosi Alice, Barczyk Adam, et al. 2010. "Oxidative/nitrosative stress selectively altered A(2B) adenosine receptors in chronic obstructive pulmonary disease." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 24 (4) doi:10.1096/fj.09-139485
Barnes Peter J 2010. "Theophylline." Pharmaceuticals (Basel, Switzerland) 3 (3) doi:10.3390/ph3030725
Barnes Peter J 2010. "Inhaled Corticosteroids." Pharmaceuticals (Basel, Switzerland) 3 (3) doi:10.3390/ph3030514
Paredi Paolo, Goldman Michael, Alamen Almahdi, Ausin Pilar, Usmani Omar S, et al. 2010. "Comparison of inspiratory and expiratory resistance and reactance in patients with asthma and chronic obstructive pulmonary disease." Thorax 65 (3) doi:10.1136/thx.2009.120790
Zhang Jingying, Yao Xin, Yu Rongbin, Bai Jianling, Sun Yun, et al. 2010. "Exhaled carbon monoxide in asthmatics: a meta-analysis." Respiratory research 11 doi:10.1186/1465-9921-11-50
Barnes Peter J 2010. "Inhaled corticosteroids in COPD: a controversy." Respiration; international review of thoracic diseases 80 (2) doi:10.1159/000315416
Montuschi Paolo, Barnes Peter J, Ciabattoni Giovanni 2010. "Measurement of 8-isoprostane in exhaled breath condensate." Methods in molecular biology (Clifton, N.J.) 594 doi:10.1007/978-1-60761-411-1_5
Brindicci Caterina, Kharitonov Sergei A, Ito Misako, Elliott Mark W, Hogg James C, et al. 2010. "Nitric oxide synthase isoenzyme expression and activity in peripheral lung tissue of patients with chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 181 (1) doi:10.1164/rccm.200904-0493OC
Barnes Peter J 2010. "New therapies for chronic obstructive pulmonary disease." Medical principles and practice : international journal of the Kuwait University, Health Science Centre 19 (5) doi:10.1159/000316368

2009

Charron Catherine E, Chou Pai-Chien, Coutts David J C, Kumar Vaibhav, To Masako, et al. 2009. "Hypoxia-inducible factor 1alpha induces corticosteroid-insensitive inflammation via reduction of histone deacetylase-2 transcription." The Journal of biological chemistry 284 (52) doi:10.1074/jbc.M109.025387
Barnes Peter J 2009. "The cytokine network in chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 41 (6) doi:10.1165/rcmb.2009-0220TR
Barnes Peter J 2009. "Targeting the epigenome in the treatment of asthma and chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 6 (8) doi:10.1513/pats.200907-071DP
Barnes Peter J 2009. "Histone deacetylase-2 and airway disease." Therapeutic advances in respiratory disease 3 (5) doi:10.1177/1753465809348648
Stockley Robert A, Mannino David, Barnes Peter J 2009. "Burden and pathogenesis of chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 6 (6) doi:10.1513/pats.200904-016DS
Nakamaru Yuji, Vuppusetty Chaitanya, Wada Hiroo, Milne Jill C, Ito Misako, et al. 2009. "A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23 (9) doi:10.1096/fj.08-125468
Caramori Gaetano, Casolari Paolo, Di Gregorio Carmela, Saetta Marina, Baraldo Simonetta, et al. 2009. "MUC5AC expression is increased in bronchial submucosal glands of stable COPD patients." Histopathology 55 (3) doi:10.1111/j.1365-2559.2009.03377.x
Salvi Sundeep S, Barnes Peter J 2009. "Chronic obstructive pulmonary disease in non-smokers." Lancet 374 (9691) doi:10.1016/S0140-6736(09)61303-9
Hansel Trevor T, Barnes Peter J 2009. "New drugs for exacerbations of chronic obstructive pulmonary disease." Lancet 374 (9691) doi:10.1016/S0140-6736(09)61342-8
Osoata Grace O, Yamamura Satoshi, Ito Misako, Vuppusetty Chaitanya, Adcock Ian M, et al. 2009. "Nitration of distinct tyrosine residues causes inactivation of histone deacetylase 2." Biochemical and biophysical research communications 384 (3) doi:10.1016/j.bbrc.2009.04.128
Osoata Grace O, Hanazawa Toyoyuki, Brindicci Caterina, Ito Misako, Barnes Peter J, et al. 2009. "Peroxynitrite elevation in exhaled breath condensate of COPD and its inhibition by fudosteine." Chest 135 (6) doi:10.1378/chest.08-2105
Papi Alberto, Caramori Gaetano, Adcock Ian M, Barnes Peter J 2009. "Rescue treatment in asthma. More than as-needed bronchodilation." Chest 135 (6) doi:10.1378/chest.08-2536
Barnes Peter J, Adcock Ian M 2009. "Glucocorticoid resistance in inflammatory diseases." Lancet 373 (9678) doi:10.1016/S0140-6736(09)60326-3
Maneechotesuwan Kittipong, Yao Xin, Ito Kazuhiro, Jazrawi Elen, Usmani Omar S, et al. 2009. "Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease." PLoS medicine 6 (5) doi:10.1371/journal.pmed.1000076
Wenzel Sally E, Barnes Peter J, Bleecker Eugene R, Bousquet Jean, Busse William, et al. 2009. "A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma." American journal of respiratory and critical care medicine 179 (7) doi:10.1164/rccm.200809-1512OC
Marwick John A, Caramori Gaetano, Stevenson Christopher S, Casolari Paolo, Jazrawi Elen, et al. 2009. "Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice." American journal of respiratory and critical care medicine 179 (7) doi:10.1164/rccm.200810-1570OC
Brindicci Caterina, Ito Kazuhiro, Torre Olga, Barnes Peter J, Kharitonov Sergei A 2009. "Effects of aminoguanidine, an inhibitor of inducible nitric oxide synthase, on nitric oxide production and its metabolites in healthy control subjects, healthy smokers, and COPD patients." Chest 135 (2) doi:10.1378/chest.08-0964
Barnes Peter J 2009. "Role of HDAC2 in the pathophysiology of COPD." Annual review of physiology 71 doi:10.1146/annurev.physiol.010908.163257
Maneechotesuwan Kittipong, Wamanuttajinda Valla, Kasetsinsombat Kanda, Huabprasert Sukit, Yaikwawong Metha, et al. 2009. "Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma." The Journal of allergy and clinical immunology 123 (1) doi:10.1016/j.jaci.2008.10.018
Ito Kazuhiro, Barnes Peter J 2009. "COPD as a disease of accelerated lung aging." Chest 135 (1) doi:10.1378/chest.08-1419

2008

Marwick John A, Wallis Gillian, Meja Koremu, Kuster Bernhard, Bouwmeester Tewis, et al. 2008. "Oxidative stress modulates theophylline effects on steroid responsiveness." Biochemical and biophysical research communications 377 (3) doi:10.1016/j.bbrc.2008.10.065
O'Byrne Paul M, Naya Ian P, Kallen Anders, Postma Dirkje S, Barnes Peter J 2008. "Increasing doses of inhaled corticosteroids compared to adding long-acting inhaled beta2-agonists in achieving asthma control." Chest 134 (6) doi:10.1378/chest.08-1018
Barnes Peter J 2008. "Emerging pharmacotherapies for COPD." Chest 134 (6) doi:10.1378/chest.08-1385
Barnes Peter J 2008. "Future treatments for chronic obstructive pulmonary disease and its comorbidities." Proceedings of the American Thoracic Society 5 (8) doi:10.1513/pats.200807-069TH
Ito Kazuhiro, Herbert Cristan, Siegle Jessica S, Vuppusetty Chaitanya, Hansbro Nicole, et al. 2008. "Steroid-resistant neutrophilic inflammation in a mouse model of an acute exacerbation of asthma." American journal of respiratory cell and molecular biology 39 (5) doi:10.1165/rcmb.2008-0028OC
Barnes Peter J 2008. "The cytokine network in asthma and chronic obstructive pulmonary disease." The Journal of clinical investigation 118 (11) doi:10.1172/JCI36130
Barnes Peter J, Baldock Clive, Meikle Steven R, Fulton Roger R 2008. "Benchmarking of a motion sensing system for medical imaging and radiotherapy." Physics in medicine and biology 53 (20) doi:10.1088/0031-9155/53/20/019
Erin Edward M, Zacharasiewicz Angela S, Nicholson Grant C, Tan Andrew J, Neighbour Helen, et al. 2008. "Rapid effect of inhaled ciclesonide in asthma: a randomized, placebo-controlled study." Chest 134 (4) doi:10.1378/chest.07-2575
Lucidi Vincenzina, Ciabattoni Giovanni, Bella Sergio, Barnes Peter J, Montuschi Paolo 2008. "Exhaled 8-isoprostane and prostaglandin E(2) in patients with stable and unstable cystic fibrosis." Free radical biology & medicine 45 (6) doi:10.1016/j.freeradbiomed.2008.06.026
Kaur Manminder, Holden Neil S, Wilson Sylvia M, Sukkar Maria B, Chung Kian Fan, et al. 2008. "Effect of beta2-adrenoceptor agonists and other cAMP-elevating agents on inflammatory gene expression in human ASM cells: a role for protein kinase A." American journal of physiology. Lung cellular and molecular physiology 295 (3) doi:10.1152/ajplung.00046.2008
Adcock Ian M, Barnes Peter J 2008. "Molecular mechanisms of corticosteroid resistance." Chest 134 (2) doi:10.1378/chest.08-0440
Barnes Peter J 2008. "Role of GATA-3 in allergic diseases." Current molecular medicine 8 (5) doi:
Pedersen Lars, Lund Thomas K, Barnes Peter J, Kharitonov Sergei A, Backer Vibeke 2008. "Airway responsiveness and inflammation in adolescent elite swimmers." The Journal of allergy and clinical immunology 122 (2) doi:10.1016/j.jaci.2008.04.041
Sturton Graham, Persson Carl, Barnes Peter J 2008. "Small airways: an important but neglected target in the treatment of obstructive airway diseases." Trends in pharmacological sciences 29 (7) doi:10.1016/j.tips.2008.04.003
Perttunen Heli, Moilanen Eeva, Zhang Xianzhi, Barnes Peter J, Kankaanranta Hannu 2008. "Beta2-agonists potentiate corticosteroid-induced neutrophil survival." COPD 5 (3) doi:10.1080/15412550802092969
Barnes Peter J 2008. "Frontrunners in novel pharmacotherapy of COPD." Current opinion in pharmacology 8 (3) doi:10.1016/j.coph.2008.03.001
Ahmad Tehireem, Barnes Peter J, Adcock Ian M 2008. "Overcoming steroid insensitivity in smoking asthmatics." Current opinion in investigational drugs (London, England : 2000) 9 (5) doi:
Barnes Peter J 2008. "Immunology of asthma and chronic obstructive pulmonary disease." Nature reviews. Immunology 8 (3) doi:10.1038/nri2254
Erin Edward M, Jenkins Gavin R, Kon Onn Min, Zacharasiewicz Angela S, Nicholson Grant C, et al. 2008. "Optimized dialysis and protease inhibition of sputum dithiothreitol supernatants." American journal of respiratory and critical care medicine 177 (2) doi:10.1164/rccm.200603-311OC
Leaker Brian R, O'Connor B, Hansel Trevor T, Barnes Peter J, Meng Lixen, et al. 2008. "Safety of regadenoson, an adenosine A2A receptor agonist for myocardial perfusion imaging, in mild asthma and moderate asthma patients: a randomized, double-blind, placebo-controlled trial." Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 15 (3) doi:10.1016/j.nuclcard.2008.02.009
Maneechotesuwan Kittipong, Supawita Sirinya, Kasetsinsombat Kanda, Wongkajornsilp Adisak, Barnes Peter J 2008. "Sputum indoleamine-2, 3-dioxygenase activity is increased in asthmatic airways by using inhaled corticosteroids." The Journal of allergy and clinical immunology 121 (1) doi:10.1016/j.jaci.2007.10.011
Sturton Richard G, Trifilieff Alexandre, Nicholson Andrew G, Barnes Peter J 2008. "Pharmacological characterization of indacaterol, a novel once daily inhaled 2 adrenoceptor agonist, on small airways in human and rat precision-cut lung slices." The Journal of pharmacology and experimental therapeutics 324 (1) doi:10.1124/jpet.107.129296
Costa Claudia, Rufino Rogerio, Traves Suzanne L, Lapa E Silva Jose Roberto, Barnes Peter J, Donnelly Louise E 2008. "CXCR3 and CCR5 chemokines in induced sputum from patients with COPD." Chest 133 (1) doi:10.1378/chest.07-0393
Tudhope Susan J, Finney-Hayward Tricia K, Nicholson Andrew G, Mayer Ruth J, Barnette Mary S, et al. 2008. "Different mitogen-activated protein kinase-dependent cytokine responses in cells of the monocyte lineage." The Journal of pharmacology and experimental therapeutics 324 (1) doi:10.1124/jpet.107.127670

2007

Montuschi Paolo, Mondino Chiara, Koch Pierluigi, Ciabattoni Giovanni, Barnes Peter J, Baviera Giuseppe 2007. "Effects of montelukast treatment and withdrawal on fractional exhaled nitric oxide and lung function in children with asthma." Chest 132 (6) doi:10.1378/chest.07-1587
Tudhope Susan J, Catley Matthew C, Fenwick Peter S, Russell Richard E K, Rumsey William L, et al. 2007. "The role of IkappaB kinase 2, but not activation of NF-kappaB, in the release of CXCR3 ligands from IFN-gamma-stimulated human bronchial epithelial cells." Journal of immunology (Baltimore, Md. : 1950) 179 (9) doi:
Rabe Klaus F, Hurd Suzanne, Anzueto Antonio, Barnes Peter J, Buist Sonia A, et al. 2007. "Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary." American journal of respiratory and critical care medicine 176 (6) doi:10.1164/rccm.200703-456SO
Brindicci Caterina, Ito Kazuhiro, Barnes Peter J, Kharitonov Sergei A 2007. "Effect of an inducible nitric oxide synthase inhibitor on differential flow-exhaled nitric oxide in asthmatic patients and healthy volunteers." Chest 132 (2) doi:10.1378/chest.06-3046
Maneechotesuwan Kittipong, Essilfie-Quaye Sarah, Kharitonov Sergei A, Adcock Ian M, Barnes Peter J 2007. "Loss of control of asthma following inhaled corticosteroid withdrawal is associated with increased sputum interleukin-8 and neutrophils." Chest 132 (1) doi:10.1378/chest.06-2982
Barnes Peter J 2007. "New molecular targets for the treatment of neutrophilic diseases." The Journal of allergy and clinical immunology 119 (5) doi:10.1016/j.jaci.2007.01.015
Newton Robert, Holden Neil S, Catley Matthew C, Oyelusi Wale, Leigh Richard, et al. 2007. "Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IkappaB kinase inhibitors." The Journal of pharmacology and experimental therapeutics 321 (2) doi:10.1124/jpet.106.118125
Brindicci Caterina, Ito Kazuhiro, Barnes Peter J, Kharitonov Sergei A 2007. "Differential flow analysis of exhaled nitric oxide in patients with asthma of differing severity." Chest 131 (5) doi:10.1378/chest.06-2531
Paredi Paolo, Ward Simon, Cramer Derek, Barnes Peter J, Kharitonov Sergei A 2007. "Normal bronchial blood flow in COPD is unaffected by inhaled corticosteroids and correlates with exhaled nitric oxide." Chest 131 (4) doi:10.1378/chest.06-2154
Maneechotesuwan Kittipong, Xin Yao, Ito Kazuhiro, Jazrawi Elen, Lee Kang-Yun, et al. 2007. "Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3." Journal of immunology (Baltimore, Md. : 1950) 178 (4) doi:
Williams Andrew E, Moschos Sterghios A, Perry Mark M, Barnes Peter J, Lindsay Mark A 2007. "Maternally imprinted microRNAs are differentially expressed during mouse and human lung development." Developmental dynamics : an official publication of the American Association of Anatomists 236 (2) doi:10.1002/dvdy.21047
Barnes Peter J 2007. "The problem of cough and development of novel antitussives." Pulmonary pharmacology & therapeutics 20 (4) doi:10.1016/j.pupt.2006.11.001
Nicholson Grant C, Tennant Rachel C, Carpenter Donald C, Sarau Henry M, Kon Onn Min, et al. 2007. "A novel flow cytometric assay of human whole blood neutrophil and monocyte CD11b levels: upregulation by chemokines is related to receptor expression, comparison with neutrophil shape change, and effects of a chemokine receptor (CXCR2) antagonist." Pulmonary pharmacology & therapeutics 20 (1) doi:10.1016/j.pupt.2005.11.009

2006

Vasavda Nisha, Eichholtz Thomas, Takahashi Atsushi, Affleck Karen, Matthews John G, et al. 2006. "Expression of nonmuscle cofilin-1 and steroid responsiveness in severe asthma." The Journal of allergy and clinical immunology 118 (5) doi:10.1016/j.jaci.2006.07.039
Kharitonov Sergei A, Barnes Peter J 2006. "Exhaled biomarkers." Chest 130 (5) doi:10.1378/chest.130.5.1541
Barnes Peter J 2006. "New therapies for asthma." Trends in molecular medicine 12 (11) doi:10.1016/j.molmed.2006.09.006
Donnelly Louise E, Barnes Peter J 2006. "Chemokine receptors as therapeutic targets in chronic obstructive pulmonary disease." Trends in pharmacological sciences 27 (10) doi:10.1016/j.tips.2006.08.001
Erin Edward M, Leaker Brian R, Nicholson Grant C, Tan Andrew J, Green Linda M, et al. 2006. "The effects of a monoclonal antibody directed against tumor necrosis factor-alpha in asthma." American journal of respiratory and critical care medicine 174 (7) doi:10.1164/rccm.200601-072OC
Barnes Peter J 2006. "Transcription factors in airway diseases." Laboratory investigation; a journal of technical methods and pathology 86 (9) doi:10.1038/labinvest.3700456
Paraskakis Emmanouil, Brindicci Caterina, Fleming Louise, Krol Renata, Kharitonov Sergei A, et al. 2006. "Measurement of bronchial and alveolar nitric oxide production in normal children and children with asthma." American journal of respiratory and critical care medicine 174 (3) doi:10.1164/rccm.200506-962OC
Catley Matthew C, Sukkar Maria B, Chung K Fan, Jaffee Bruce, Liao Sha-Mei, et al. 2006. "Validation of the anti-inflammatory properties of small-molecule IkappaB Kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and IKK2 in human airways smooth muscle." Molecular pharmacology 70 (2) doi:10.1124/mol.106.023150
Montuschi Paolo, Mondino Chiara, Koch Pierluigi, Barnes Peter J, Ciabattoni Giovanni 2006. "Effects of a leukotriene receptor antagonist on exhaled leukotriene E4 and prostanoids in children with asthma." The Journal of allergy and clinical immunology 118 (2) doi:10.1016/j.jaci.2006.04.010
Hew Mark, Bhavsar Pankaj, Torrego Alfons, Meah Sally, Khorasani Nadia, et al. 2006. "Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma." American journal of respiratory and critical care medicine 174 (2) doi:10.1164/rccm.200512-1930OC
Barnes Peter J, Chowdhury Badrul, Kharitonov Sergei A, Magnussen Helgo, Page Clive P, et al. 2006. "Pulmonary biomarkers in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 174 (1) doi:10.1164/rccm.200510-1659PP
Barnes Peter J 2006. "How corticosteroids control inflammation: Quintiles Prize Lecture 2005." British journal of pharmacology 148 (3) doi:10.1038/sj.bjp.0706736
Hansel Trevor T, Benezet Olivier, Kafé Henri, Ponitz Hans-Hermann, Cheung David, et al. 2006. "A multinational, 12-week, randomized study comparing the efficacy and tolerability of ciclesonide and budesonide in patients with asthma." Clinical therapeutics 28 (6) doi:10.1016/j.clinthera.2006.06.014
Barczyk Adam, Pierzchała Władysław, Kon Onn M, Cosio Borja, Adcock Ian M, Barnes Peter J 2006. "Cytokine production by bronchoalveolar lavage T lymphocytes in chronic obstructive pulmonary disease." The Journal of allergy and clinical immunology 117 (6) doi:10.1016/j.jaci.2006.02.013
Barnes Peter J 2006. "Receptor heterodimerization: a new level of cross-talk." The Journal of clinical investigation 116 (5) doi:10.1172/JCI28535
Barnes Peter J 2006. "Corticosteroids: the drugs to beat." European journal of pharmacology 533 (1-3) doi:10.1016/j.ejphar.2005.12.052
Varani Katia, Caramori Gaetano, Vincenzi Fabrizio, Adcock Ian, Casolari Paolo, et al. 2006. "Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 173 (4) doi:10.1164/rccm.200506-869OC
Ito Kazuhiro, Yamamura Satoshi, Essilfie-Quaye Sarah, Cosio Borja, Ito Misako, et al. 2006. "Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression." The Journal of experimental medicine 203 (1) doi:10.1084/jem.20050466
Biddiscombe Martyn F, Barnes Peter J, Usmani Omar S 2006. "Generating monodisperse pharmacological aerosols using the spinning-top aerosol generator." Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 19 (3) doi:10.1089/jam.2006.19.245
Rogers Duncan F, Barnes Peter J 2006. "Treatment of airway mucus hypersecretion." Annals of medicine 38 (2) doi:10.1080/07853890600585795
Lex Christiane, Zacharasiewicz Angela, Payne Donald N R, Wilson Nicola M, Nicholson Andrew G, et al. 2006. "Exhaled breath condensate cysteinyl leukotrienes and airway remodeling in childhood asthma: a pilot study." Respiratory research 7 doi:10.1186/1465-9921-7-63
Barnes Peter J 2006. "Reduced histone deacetylase in COPD: clinical implications." Chest 129 (1) doi:10.1378/chest.129.1.151
Lee Kang-Yun, Ito Kazuhiro, Hayashi Ryuji, Jazrawi Elen P I, Barnes Peter J, Adcock Ian M 2006. "NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription." Journal of immunology (Baltimore, Md. : 1950) 176 (1) doi:
Barnes Peter J 2006. "Drugs for asthma." British journal of pharmacology 147 Suppl 1 doi:10.1038/sj.bjp.0706437
Barnes Peter J 2006. "Novel signal transduction modulators for the treatment of airway diseases." Pharmacology & therapeutics 109 (1-2) doi:10.1016/j.pharmthera.2005.08.001

2005

Usmani Omar S, Biddiscombe Martyn F, Barnes Peter J 2005. "Regional lung deposition and bronchodilator response as a function of beta2-agonist particle size." American journal of respiratory and critical care medicine 172 (12) doi:10.1164/rccm.200410-1414OC
Adcock Ian M, Ito Kazuhiro, Barnes Peter J 2005. "Histone deacetylation: an important mechanism in inflammatory lung diseases." COPD 2 (4) doi:
Barnes Peter J 2005. "Emerging targets for COPD therapy." Current drug targets. Inflammation and allergy 4 (6) doi:
Barnes Peter J 2005. "Targeting histone deacetylase 2 in chronic obstructive pulmonary disease treatment." Expert opinion on therapeutic targets 9 (6) doi:10.1517/14728222.9.6.1111
Ricciardolo Fabio L M, Caramori Gaetano, Ito Kazuhiro, Capelli Armando, Brun Paola, et al. 2005. "Nitrosative stress in the bronchial mucosa of severe chronic obstructive pulmonary disease." The Journal of allergy and clinical immunology 116 (5) doi:10.1016/j.jaci.2005.06.034
Basoglu Ozen K, Pelleg Amir, Essilfie-Quaye Sarah, Brindicci Caterina, Barnes Peter J, Kharitonov Sergei A 2005. "Effects of aerosolized adenosine 5'-triphosphate vs adenosine 5'-monophosphate on dyspnea and airway caliber in healthy nonsmokers and patients with asthma." Chest 128 (4) doi:10.1378/chest.128.4.1905
Maneechotesuwan Kittipong, Essilfie-Quaye Sarah, Meah Sally, Kelly Claire, Kharitonov Sergei A, et al. 2005. "Formoterol attenuates neutrophilic airway inflammation in asthma." Chest 128 (4) doi:10.1378/chest.128.4.1936
Biernacki Wojciech A, Kharitonov Sergei A, Biernacka Helen M, Barnes Peter J 2005. "Effect of montelukast on exhaled leukotrienes and quality of life in asthmatic patients." Chest 128 (4) doi:10.1378/chest.128.4.1958
Hansel Trevor T, Neighbour Helen, Erin Edward M, Tan Andrew J, Tennant Rachel C, et al. 2005. "Glycopyrrolate causes prolonged bronchoprotection and bronchodilatation in patients with asthma." Chest 128 (4) doi:10.1378/chest.128.4.1974
Usmani Omar S, Ito Kazuhiro, Maneechotesuwan Kittipong, Ito Misako, Johnson Malcolm, et al. 2005. "Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy." American journal of respiratory and critical care medicine 172 (6) doi:10.1164/rccm.200408-1041OC
Kharitonov Sergei A, Walker Lynda, Barnes Peter J 2005. "Repeatability of standardised nasal nitric oxide measurements in healthy and asthmatic adults and children." Respiratory medicine 99 (9) doi:10.1016/j.rmed.2005.02.019
Barnes Peter J 2005. "Molecular mechanisms and cellular effects of glucocorticosteroids." Immunology and allergy clinics of North America 25 (3) doi:10.1016/j.iac.2005.05.003
Sharma Rakesh, Bolger Aidan P, Rauchhaus Mathias, von Haehling Stephan, Doehner Wolfram, et al. 2005. "Cellular endotoxin desensitization in patients with severe chronic heart failure." European journal of heart failure 7 (5) doi:10.1016/j.ejheart.2004.09.014
Wada Hiroo, Kagoshima Masahiko, Ito Kazuhiro, Barnes Peter J, Adcock Ian M 2005. "5-Azacytidine suppresses RNA polymerase II recruitment to the SLPI gene." Biochemical and biophysical research communications 331 (1) doi:10.1016/j.bbrc.2005.03.138
Ito Kazuhiro, Ito Misako, Elliott W Mark, Cosio Borja, Caramori Gaetano, et al. 2005. "Decreased histone deacetylase activity in chronic obstructive pulmonary disease." The New England journal of medicine 352 (19) doi:10.1056/NEJMoa041892
Catley Matthew C, Chivers Joanna E, Holden Neil S, Barnes Peter J, Newton Robert 2005. "Validation of IKK beta as therapeutic target in airway inflammatory disease by adenoviral-mediated delivery of dominant-negative IKK beta to pulmonary epithelial cells." British journal of pharmacology 145 (1) doi:10.1038/sj.bjp.0706170
Haque Rubaiyat A, Usmani Omar S, Barnes Peter J 2005. "Chronic idiopathic cough: a discrete clinical entity?" Chest 127 (5) doi:10.1378/chest.127.5.1710
Usmani Omar S, Belvisi Maria G, Patel Hema J, Crispino Natascia, Birrell Mark A, et al. 2005. "Theobromine inhibits sensory nerve activation and cough." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19 (2) doi:10.1096/fj.04-1990fje
Paredi Paolo, Kharitonov Sergei A, Barnes Peter J 2005. "Correlation of exhaled breath temperature with bronchial blood flow in asthma." Respiratory research 6 doi:10.1186/1465-9921-6-15
Adcock Ian M, Cosio Borja, Tsaprouni Loukia, Barnes Peter J, Ito Kazuhiro 2005. "Redox regulation of histone deacetylases and glucocorticoid-mediated inhibition of the inflammatory response." Antioxidants & redox signaling 7 (1-2) doi:10.1089/ars.2005.7.144
Antczak Adam, Kharitonov Sergei A, Montuschi Paolo, Gorski Pawel, Barnes Peter J 2005. "Inflammatory response to sputum induction measured by exhaled markers." Respiration; international review of thoracic diseases 72 (6) doi:10.1159/000086721
Shahid Sukhbir K, Kharitonov Sergei A, Wilson Nicola M, Bush Andrew, Barnes Peter J 2005. "Exhaled 8-isoprostane in childhood asthma." Respiratory research 6 doi:10.1186/1465-9921-6-79
Montuschi Paolo, Martello Simona, Felli Marialinda, Mondino Chiara, Barnes Peter J, Chiarotti Marcello 2005. "Liquid chromatography/mass spectrometry analysis of exhaled leukotriene B4 in asthmatic children." Respiratory research 6 doi:10.1186/1465-9921-6-119
Barnes Peter J 2005. "Theophylline in chronic obstructive pulmonary disease: new horizons." Proceedings of the American Thoracic Society 2 (4) doi:10.1513/pats.200504-024SR
Barnes Peter J 2005. "Introduction: how can we improve asthma management?" Current medical research and opinion 21 Suppl 4 doi:10.1185/030079905X61712
Barnes Peter J 2005. "Achieving asthma control." Current medical research and opinion 21 Suppl 4 doi:10.1185/030079905X61730

2004

Barnes Peter J 2004. "The role of anticholinergics in chronic obstructive pulmonary disease." The American journal of medicine 117 Suppl 12A doi:
Barnes Peter J 2004. "New drugs for asthma." Discovery medicine 4 (24) doi:
Barnes Peter J 2004. "Mediators of chronic obstructive pulmonary disease." Pharmacological reviews 56 (4) doi:10.1124/pr.56.4.2
Montuschi Paolo, Barnes Peter J, Roberts L Jackson 2004. "Isoprostanes: markers and mediators of oxidative stress." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 18 (15) doi:10.1096/fj.04-2330rev
Smith Susan J, Cieslinski Lenora B, Newton Robert, Donnelly Louise E, Fenwick Peter S, et al. 2004. "Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a selective inhibitor of phosphodiesterase 7: in vitro studies in human monocytes, lung macrophages, and CD8+ T-lymphocytes." Molecular pharmacology 66 (6) doi:10.1124/mol.104.002246
Donnelly Louise E, Barnes Peter J 2004. "Acidic mammalian chitinase--a potential target for asthma therapy." Trends in pharmacological sciences 25 (10) doi:10.1016/j.tips.2004.08.002
Donnelly Louise E, Newton Robert, Kennedy Gina E, Fenwick Peter S, Leung Rachel H F, et al. 2004. "Anti-inflammatory effects of resveratrol in lung epithelial cells: molecular mechanisms." American journal of physiology. Lung cellular and molecular physiology 287 (4) doi:10.1152/ajplung.00110.2004
Barnes Peter J 2004. "New drugs for asthma." Nature reviews. Drug discovery 3 (10) doi:10.1038/nrd1524
Barnes Peter J 2004. "The size of the problem of managing asthma." Respiratory medicine 98 Suppl B doi:
Mondino Chiara, Ciabattoni Giovanni, Koch Pierluigi, Pistelli Riccardo, Trové Andrea, et al. 2004. "Effects of inhaled corticosteroids on exhaled leukotrienes and prostanoids in asthmatic children." The Journal of allergy and clinical immunology 114 (4) doi:10.1016/j.jaci.2004.06.054
Chivers Joanna E, Cambridge Lisa M, Catley Matthew C, Mak Judith C, Donnelly Louise E, et al. 2004. "Differential effects of RU486 reveal distinct mechanisms for glucocorticoid repression of prostaglandin E release." European journal of biochemistry / FEBS 271 (20) doi:10.1111/j.1432-1033.2004.04342.x
Cosio Borja G, Tsaprouni Loukia, Ito Kazuhiro, Jazrawi Elen, Adcock Ian M, Barnes Peter J 2004. "Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages." The Journal of experimental medicine 200 (5) doi:10.1084/jem.20040416
Ichinose Masakazu, Barnes Peter J 2004. "Cytokine-directed therapy in asthma." Current drug targets. Inflammation and allergy 3 (3) doi:
Traves Suzanne L, Smith Susan J, Barnes Peter J, Donnelly Louise E 2004. "Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2." Journal of leukocyte biology 76 (2) doi:10.1189/jlb.1003495
Cosío Borja G, Mann Buphinder, Ito Kazuhiro, Jazrawi Elen, Barnes Peter J, et al. 2004. "Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma." American journal of respiratory and critical care medicine 170 (2) doi:10.1164/rccm.200305-659OC
Barnes Peter J 2004. "COPD: is there light at the end of the tunnel?" Current opinion in pharmacology 4 (3) doi:10.1016/j.coph.2004.03.001
Matthews John G, Ito Kazuhiro, Barnes Peter J, Adcock Ian M 2004. "Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients." The Journal of allergy and clinical immunology 113 (6) doi:10.1016/j.jaci.2004.03.018
Carpagnano Giovanna E, Barnes Peter J, Francis Jackie, Wilson Nicola, Bush Andrew, Kharitonov Sergei A 2004. "Breath condensate pH in children with cystic fibrosis and asthma: a new noninvasive marker of airway inflammation?" Chest 125 (6) doi:
Meja Koremu K, Catley Matthew C, Cambridge Lisa M, Barnes Peter J, Lum Hazel, et al. 2004. "Adenovirus-mediated delivery and expression of a cAMP-dependent protein kinase inhibitor gene to BEAS-2B epithelial cells abolishes the anti-inflammatory effects of rolipram, salbutamol, and prostaglandin E2: a comparison with H-89." The Journal of pharmacology and experimental therapeutics 309 (2) doi:10.1124/jpet.103.060020
Catley Matthew C, Cambridge Lisa M, Nasuhara Yasuyuki, Ito Kazuhiro, Chivers Joanna E, et al. 2004. "Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-kappaB DNA binding." The Journal of biological chemistry 279 (18) doi:10.1074/jbc.M400765200
Bergmann Martin W, Staples Karl J, Smith Susan J, Barnes Peter J, Newton Robert 2004. "Glucocorticoid inhibition of granulocyte macrophage-colony-stimulating factor from T cells is independent of control by nuclear factor-kappaB and conserved lymphokine element 0." American journal of respiratory cell and molecular biology 30 (4) doi:10.1165/rcmb.2003-0295OC
Bergmann Martin W, Staples Karl J, Barnes Peter J, Newton Robert 2004. "Nuclear factor-kappaB does not mediate the inhibitory effects of dexamethasone on granulocyte-macrophage colony-stimulating factor expression." Immunology 111 (4) doi:10.1111/j.0019-2805.2004.01833.x
Barnes Peter J 2004. "Asthma guidelines: recommendations versus reality." Respiratory medicine 98 Suppl A doi:
Barnes Peter J 2004. "Alveolar macrophages as orchestrators of COPD." COPD 1 (1) doi:10.1081/COPD-120028701
Yuda Hisamichi, Adachi Yukihiko, Taguchi Osamu, Gabazza Esteban C, Hataji Osamu, et al. 2004. "Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice." Blood 103 (6) doi:10.1182/blood-2003-06-1980
Koch Andrea, Giembycz Mark, Ito Kazuhiro, Lim Sam, Jazrawi Elen, et al. 2004. "Mitogen-activated protein kinase modulation of nuclear factor-kappaB-induced granulocyte macrophage-colony-stimulating factor release from human alveolar macrophages." American journal of respiratory cell and molecular biology 30 (3) doi:10.1165/rcmb.2003-0122OC
Barnes Peter J, Ito Kazuhiro, Adcock Ian M 2004. "Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase." Lancet 363 (9410) doi:10.1016/S0140-6736(04)15650-X
Holden Neil S, Catley Matthew C, Cambridge Lisa M, Barnes Peter J, Newton Robert 2004. "ICAM-1 expression is highly NF-kappaB-dependent in A549 cells. No role for ERK and p38 MAPK." European journal of biochemistry / FEBS 271 (4) doi:
Bowler Russell P, Barnes Peter J, Crapo James D 2004. "The role of oxidative stress in chronic obstructive pulmonary disease." COPD 1 (2) doi:
Kankaanranta Hannu, Lahdensuo Aarne, Moilanen Eeva, Barnes Peter J 2004. "Add-on therapy options in asthma not adequately controlled by inhaled corticosteroids: a comprehensive review." Respiratory research 5 doi:10.1186/1465-9921-5-17
Usmani Omar S, Biddiscombe Martyn F, Underwood S Richard, Barnes Peter J 2004. "Characterization of the generation of radiolabeled monodisperse albuterol particles using the spinning-top aerosol generator." Journal of nuclear medicine : official publication, Society of Nuclear Medicine 45 (1) doi:
Hansel Trevor T, Tennant Rachel C, Tan Andrew J, Higgins Lorna A, Neighbour Helen, et al. 2004. "Theophylline: mechanism of action and use in asthma and chronic obstructive pulmonary disease." Drugs of today (Barcelona, Spain : 1998) 40 (1) doi:
Barnes Peter J, Hansel Trevor T 2004. "Prospects for new drugs for chronic obstructive pulmonary disease." Lancet 364 (9438) doi:10.1016/S0140-6736(04)17025-6
Horváth Ildikó, Donnelly Louise E, Kiss András, Balint Beata, Kharitonov Sergei A, Barnes Peter J 2004. "Exhaled nitric oxide and hydrogen peroxide concentrations in asthmatic smokers." Respiration; international review of thoracic diseases 71 (5) doi:10.1159/000080630
Kharitonov Sergei A, Barnes Peter J 2004. "Effects of corticosteroids on noninvasive biomarkers of inflammation in asthma and chronic obstructive pulmonary disease." Proceedings of the American Thoracic Society 1 (3) doi:10.1513/pats.200402-011MS
Adcock Ian M, Ito Kaz, Barnes Peter J 2004. "Glucocorticoids: effects on gene transcription." Proceedings of the American Thoracic Society 1 (3) doi:10.1513/pats.200402-001MS
Barnes Peter J 2004. "Corticosteroid resistance in airway disease." Proceedings of the American Thoracic Society 1 (3) doi:10.1513/pats.200402-014MS
Barnes Peter J 2004. "Distribution of receptor targets in the lung." Proceedings of the American Thoracic Society 1 (4) doi:10.1513/pats.200409-045MS

2003

Barnes Peter J 2003. "Cytokine-directed therapies for the treatment of chronic airway diseases." Cytokine & growth factor reviews 14 (6) doi:
Bucchioni Enrica, Kharitonov Sergei A, Allegra Luigi, Barnes Peter J 2003. "High levels of interleukin-6 in the exhaled breath condensate of patients with COPD." Respiratory medicine 97 (12) doi:
Allen Maxine, Heinzmann Andrea, Noguchi Emiko, Abecasis Gonçalo, Broxholme John, et al. 2003. "Positional cloning of a novel gene influencing asthma from chromosome 2q14." Nature genetics 35 (3) doi:10.1038/ng1256
Usmani Omar S, Biddiscombe Martyn F, Nightingale Julia A, Underwood S Richard, Barnes Peter J 2003. "Effects of bronchodilator particle size in asthmatic patients using monodisperse aerosols." Journal of applied physiology (Bethesda, Md. : 1985) 95 (5) doi:10.1152/japplphysiol.00525.2003
Carpagnano Giovanna E, Kharitonov Sergei A, Resta Onofrio, Foschino-Barbaro Maria P, Gramiccioni Enzo, Barnes Peter J 2003. "8-Isoprostane, a marker of oxidative stress, is increased in exhaled breath condensate of patients with obstructive sleep apnea after night and is reduced by continuous positive airway pressure therapy." Chest 124 (4) doi:
Patel Hema J, Birrell Mark A, Crispino Natascia, Hele David J, Venkatesan Priya, et al. 2003. "Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guinea-pigs by cannabinoid (CB2) receptor activation." British journal of pharmacology 140 (2) doi:10.1038/sj.bjp.0705435
Staples Karl J, Bergmann Martin W, Barnes Peter J, Newton Robert 2003. "Evidence for post-transcriptional regulation of interleukin-5 by dexamethasone." Immunology 109 (4) doi:
Csoma Zsuzsanna, Bush Andrew, Wilson Nicola M, Donnelly Louise, Balint Beatrix, et al. 2003. "Nitric oxide metabolites are not reduced in exhaled breath condensate of patients with primary ciliary dyskinesia." Chest 124 (2) doi:
von Haehling Stephan, Genth-Zotz Sabine, Sharma Rakesh, Bolger Aidan P, Doehner Wolfram, et al. 2003. "The relationship between age and production of tumour necrosis factor-alpha in healthy volunteers and patients with chronic heart failure." International journal of cardiology 90 (2-3) doi:
Catley Matthew C, Chivers Joanna E, Cambridge Lisa M, Holden Neil, Slater Donna M, et al. 2003. "IL-1beta-dependent activation of NF-kappaB mediates PGE2 release via the expression of cyclooxygenase-2 and microsomal prostaglandin E synthase." FEBS letters 547 (1-3) doi:
Hansel Trevor T, Kharitonov Sergei A, Donnelly Louise E, Erin Edward M, Currie Mark G, et al. 2003. "A selective inhibitor of inducible nitric oxide synthase inhibits exhaled breath nitric oxide in healthy volunteers and asthmatics." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 17 (10) doi:10.1096/fj.02-0633fje
Baraldi Eugenio, Ghiro Laura, Piovan Vania, Carraro Silvia, Ciabattoni Giovanni, et al. 2003. "Increased exhaled 8-isoprostane in childhood asthma." Chest 124 (1) doi:
Zhang Xianzhi, Msc, Moilanen Eeva, Lahti Aleksi, Hämäläinen Mari, et al. 2003. "Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5." The Journal of allergy and clinical immunology 112 (1) doi:
Barnes Peter J 2003. "Anti-leukotrienes: here to stay?" Current opinion in pharmacology 3 (3) doi:
Tennant Rachel C, Erin Edward M, Barnes Peter J, Hansel Trevor T 2003. "Long-acting beta 2-adrenoceptor agonists or tiotropium bromide for patients with COPD: is combination therapy justified?" Current opinion in pharmacology 3 (3) doi:
Zhang Youming, Leaves Nicholas I, Anderson Gavin G, Ponting Chris P, Broxholme John, et al. 2003. "Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma." Nature genetics 34 (2) doi:10.1038/ng1166
Nabeyrat Elodie, Jones Gina E, Fenwick Peter S, Barnes Peter J, Donnelly Louise E 2003. "Mitogen-activated protein kinases mediate peroxynitrite-induced cell death in human bronchial epithelial cells." American journal of physiology. Lung cellular and molecular physiology 284 (6) doi:10.1152/ajplung.00178.2002
Carpagnano Giovanna E, Barnes Peter J, Geddes Duncan M, Hodson Margaret E, Kharitonov Sergei A 2003. "Increased leukotriene B4 and interleukin-6 in exhaled breath condensate in cystic fibrosis." American journal of respiratory and critical care medicine 167 (8) doi:10.1164/rccm.200203-179OC
Beeh Kai M, Kornmann Oliver, Buhl Roland, Culpitt Sarah V, Giembycz Mark A, Barnes Peter J 2003. "Neutrophil chemotactic activity of sputum from patients with COPD: role of interleukin 8 and leukotriene B4." Chest 123 (4) doi:
Biddiscombe Martyn F, Usmani Omar S, Barnes Peter J 2003. "A system for the production and delivery of monodisperse salbutamol aerosols to the lungs." International journal of pharmaceutics 254 (2) doi:
Kharitonov Sergei A, Barnes Peter J 2003. "Nitric oxide, nitrotyrosine, and nitric oxide modulators in asthma and chronic obstructive pulmonary disease." Current allergy and asthma reports 3 (2) doi:
Smith Susan J, Brookes-Fazakerley Steven, Donnelly Louise E, Barnes Peter J, Barnette Mary S, Giembycz Mark A 2003. "Ubiquitous expression of phosphodiesterase 7A in human proinflammatory and immune cells." American journal of physiology. Lung cellular and molecular physiology 284 (2) doi:10.1152/ajplung.00170.2002
Hoyt Jeffrey C, Robbins Richard A, Habib Michael, Springall David R, Buttery Lee D K, et al. 2003. "Cigarette smoke decreases inducible nitric oxide synthase in lung epithelial cells." Experimental lung research 29 (1) doi:
Barnes Peter J 2003. "New treatments for chronic obstructive pulmonary disease." Annali dell'Istituto superiore di sanità 39 (4) doi:
Culpitt Sarah V, Rogers Duncan F, Shah Pallav, De Matos Carmen, Russell Richard E K, et al. 2003. "Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 167 (1) doi:10.1164/rccm.200204-298OC
Barnes Peter J 2003. "New concepts in chronic obstructive pulmonary disease." Annual review of medicine 54 doi:10.1146/annurev.med.54.101601.152209
Barnes Peter J 2003. "Therapy of chronic obstructive pulmonary disease." Pharmacology & therapeutics 97 (1) doi:

2002

Paredi Paolo, Kharitonov Sergei A, Barnes Peter J 2002. "Analysis of expired air for oxidation products." American journal of respiratory and critical care medicine 166 (12 Pt 2) doi:10.1164/rccm.2206012
Csoma Zsuzsanna, Kharitonov Sergei A, Balint Beatrix, Bush Andrew, Wilson Nicola M, Barnes Peter J 2002. "Increased leukotrienes in exhaled breath condensate in childhood asthma." American journal of respiratory and critical care medicine 166 (10) doi:10.1164/rccm.200203-233OC
Montuschi Paolo, Nightingale Julia A, Kharitonov Sergei A, Barnes Peter J 2002. "Ozone-induced increase in exhaled 8-isoprostane in healthy subjects is resistant to inhaled budesonide." Free radical biology & medicine 33 (10) doi:
Mattos Waldo, Lim Sam, Russell Richard, Jatakanon Anon, Chung K Fan, Barnes Peter J 2002. "Matrix metalloproteinase-9 expression in asthma: effect of asthma severity, allergen challenge, and inhaled corticosteroids." Chest 122 (5) doi:
Carpagnano Giovanna E, Kharitonov Sergei A, Resta Onofrio, Foschino-Barbaro Maria P, Gramiccioni Enzo, Barnes Peter J 2002. "Increased 8-isoprostane and interleukin-6 in breath condensate of obstructive sleep apnea patients." Chest 122 (4) doi:
Russell Richard E K, Thorley Andrew, Culpitt Sarah V, Dodd Sara, Donnelly Louise E, et al. 2002. "Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases, cysteine, and serine proteases." American journal of physiology. Lung cellular and molecular physiology 283 (4) doi:10.1152/ajplung.00020.2002
Eynott Paul R, Groneberg David A, Caramori Gaetano, Adcock Ian M, Donnelly Louise E, et al. 2002. "Role of nitric oxide in allergic inflammation and bronchial hyperresponsiveness." European journal of pharmacology 452 (1) doi:
Tomita Katsuyuki, Caramori Gaetano, Lim Sam, Ito Kazuhiro, Hanazawa Toyoyuki, et al. 2002. "Increased p21(CIP1/WAF1) and B cell lymphoma leukemia-x(L) expression and reduced apoptosis in alveolar macrophages from smokers." American journal of respiratory and critical care medicine 166 (5) doi:
Hansel Trevor T, Barnes Peter J 2002. "Tiotropium bromide: a novel once-daily anticholinergic bronchodilator for the treatment of COPD." Drugs of today (Barcelona, Spain : 1998) 38 (9) doi:
Antczak Adam, Montuschi Paolo, Kharitonov Sergei, Gorski Pawel, Barnes Peter J 2002. "Increased exhaled cysteinyl-leukotrienes and 8-isoprostane in aspirin-induced asthma." American journal of respiratory and critical care medicine 166 (3) doi:10.1164/rccm.2101021
Ito Kazuhiro, Caramori Gaetano, Lim Sam, Oates Tim, Chung K Fan, et al. 2002. "Expression and activity of histone deacetylases in human asthmatic airways." American journal of respiratory and critical care medicine 166 (3) doi:10.1164/rccm.2110060
Ito Kazuhiro, Lim Sam, Caramori Gaetano, Cosio Borja, Chung K Fan, et al. 2002. "A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression." Proceedings of the National Academy of Sciences of the United States of America 99 (13) doi:10.1073/pnas.132556899
Bryan Shannon A, Jose Peter J, Topping Joanna R, Wilhelm Robert, Soderberg Carol, et al. 2002. "Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists." American journal of respiratory and critical care medicine 165 (12) doi:10.1164/rccm.200111-059OC
Barnes Peter J 2002. "New treatments for COPD." Nature reviews. Drug discovery 1 (6) doi:10.1038/nrd820
Birrell Mark A, Crispino Natascia, Hele David J, Patel Hema J, Yacoub Magdi H, et al. 2002. "Effect of dopamine receptor agonists on sensory nerve activity: possible therapeutic targets for the treatment of asthma and COPD." British journal of pharmacology 136 (4) doi:10.1038/sj.bjp.0704758
Culpitt Sarah V, de Matos Carmen, Russell Richard E, Donnelly Louise E, Rogers Duncan F, Barnes Peter J 2002. "Effect of theophylline on induced sputum inflammatory indices and neutrophil chemotaxis in chronic obstructive pulmonary disease." American journal of respiratory and critical care medicine 165 (10) doi:
De Souza Patricia M, Kankaanranta Hannu, Michael Ashour, Barnes Peter J, Giembycz Mark A, Lindsay Mark A 2002. "Caspase-catalyzed cleavage and activation of Mst1 correlates with eosinophil but not neutrophil apoptosis." Blood 99 (9) doi:
Russell Richard E K, Culpitt Sarah V, DeMatos Carmen, Donnelly Louise, Smith Michael, et al. 2002. "Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by alveolar macrophages from patients with chronic obstructive pulmonary disease." American journal of respiratory cell and molecular biology 26 (5) doi:10.1165/ajrcmb.26.5.4685
Nightingale Julia A, Rogers Duncan F, Barnes Peter J 2002. "Comparison of the effects of salmeterol and formoterol in patients with severe asthma." Chest 121 (5) doi:
Montuschi Paolo, Barnes Peter J 2002. "Analysis of exhaled breath condensate for monitoring airway inflammation." Trends in pharmacological sciences 23 (5) doi:
Shahid Sukhbir K, Kharitonov Sergei A, Wilson Nicola M, Bush Andrew, Barnes Peter J 2002. "Increased interleukin-4 and decreased interferon-gamma in exhaled breath condensate of children with asthma." American journal of respiratory and critical care medicine 165 (9) doi:10.1164/rccm.2108082
Montuschi Paolo, Barnes Peter J 2002. "Exhaled leukotrienes and prostaglandins in asthma." The Journal of allergy and clinical immunology 109 (4) doi:
Irusen Elvis, Matthews John G, Takahashi Atsushi, Barnes Peter J, Chung Kian F, Adcock Ian M 2002. "p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma." The Journal of allergy and clinical immunology 109 (4) doi:
Hislop Alison A, Mak Judith C W, Kelly David, Reader Jayne A, Barnes Peter J, Haworth Sheila G 2002. "Postnatal changes in beta-adrenoceptors in the lung and the effect of hypoxia induced pulmonary hypertension of the newborn." British journal of pharmacology 135 (6) doi:10.1038/sj.bjp.0704597
Tomita Katsuyuki, Lim Sam, Hanazawa Toyoyuki, Usmani Omar, Stirling Rob, et al. 2002. "Attenuated production of intracellular IL-10 and IL-12 in monocytes from patients with severe asthma." Clinical immunology (Orlando, Fla.) 102 (3) doi:10.1006/clim.2001.5176
Mak Judith C W, Chuang Tsu Tshen, Harris Carol A, Barnes Peter J 2002. "Increased expression of G protein-coupled receptor kinases in cystic fibrosis lung." European journal of pharmacology 436 (3) doi:
Mak Judith C W, Hisada Takeshi, Salmon Michael, Barnes Peter J, Chung K Fan 2002. "Glucocorticoids reverse IL-1beta-induced impairment of beta-adrenoceptor-mediated relaxation and up-regulation of G-protein-coupled receptor kinases." British journal of pharmacology 135 (4) doi:10.1038/sj.bjp.0704545
Paredi Paolo, Kharitonov Sergei A, Barnes Peter J 2002. "Faster rise of exhaled breath temperature in asthma: a novel marker of airway inflammation?" American journal of respiratory and critical care medicine 165 (2) doi:10.1164/ajrccm.165.2.2103053
Kharitonov Sergei A, Barnes Peter J 2002. "Biomarkers of some pulmonary diseases in exhaled breath." Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 7 (1) doi:10.1080/13547500110104233
Kankaanranta Hannu, Giembycz Mark A, Barnes Peter J, Haddad El-Bdaoui, Saarelainen Seppo, et al. 2002. "Hydrogen peroxide reverses IL-5 afforded eosinophil survival and promotes constitutive human eosinophil apoptosis." International archives of allergy and immunology 127 (1) doi:48171
Donnelly Louise E, Barnes Peter J 2002. "Expression and regulation of inducible nitric oxide synthase from human primary airway epithelial cells." American journal of respiratory cell and molecular biology 26 (1) doi:10.1165/ajrcmb.26.1.4477
Barnes Peter J 2002. "Cytokine modulators as novel therapies for asthma." Annual review of pharmacology and toxicology 42 doi:10.1146/annurev.pharmtox.42.111901.111143
Barnes Peter J 2002. "Current and future therapies for airway mucus hypersecretion." Novartis Foundation symposium 248 doi:
Barnes Peter J 2002. "Advances in chronic obstructive pulmonary disease." Transactions of the Medical Society of London 119 doi: